Acorus tatarinowii

Ethnobotanical Studies

Studies

Dosage sensitivity shapes balanced expression and gene longevity of homoeologs after whole-genome duplications in angiosperms.

Genetics
Shi T et al (2024).
Plant Cell.
DOI:
10.1093/plcell/koae227
PubMed:
39121058

New Value of Acorus tatarinowii/gramineus Leaves as a Dietary Source for Dementia Prevention.

Summary

Leaves of Schott and Solander show promise in treating dementia. Simple crush powder has strongest effect on tauopathy and other pathologies. Potential dietary source for dementia prevention.

Neuroscience
Umeda T et al (2024).
Nutrients.
DOI:
10.3390/nu16111589
PubMed:
38892521

[Analysis of active components of Acorus tatarinowii extracts and its activity against dust mites].

Wang H et al (2024).
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi.
DOI:
10.16250/j.32.1374.2023034
PubMed:
38857963

Acorus tatarinowii oils exert protective effects on microglia-mediated inflammatory injury via restoring gut microbiota composition in experimental stroke rats.

Summary

Researchers studied the effects of Acorus tatarinowii oils on microglial inflammation after ischemic stroke. Results showed AT oils reduced cerebral damage, inflammation, and improved gut microbiota balance. Gut microbiota played a crucial role in the protective effects of AT oils.

CardiologyGastroenterologyImmunologyNeuroscience
Huang Y et al (2024).
Brain Res Bull.
DOI:
10.1016/j.brainresbull.2024.110990
PubMed:
38821245

Molecular mechanism of Chang Shen Hua volatile oil modulating brain cAMP-PKA-CREB pathway to improve depression-like behavior in rats.

Summary

Researchers combined essential oils from Acorus tatarinowii and Panax ginseng with Albizia julibrissin flower oil to create a new treatment called CSHVO for depression. CSHVO's effects and mechanisms are still unknown.

Neuroscience
Zhang S et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155729
PubMed:
38772184

Modified Amber Particles as a Stabilizer to Construct Oil-in-Water Pickering Emulsions for Improved Thermal Stability of Acorus tatarinowii Essential Oil.

Phytochemistry
Qu Z et al (2024).
ACS Omega.
DOI:
10.1021/acsomega.3c08110
PubMed:
38764633

Structural identification and anti-neuroinflammatory effect of a heteropolysaccharide ATP50-3 from Acorus tatarinowii rhizome.

Summary

Crude polysaccharide AT50 from Acorus tatarinowii improves memory and reduces neuroinflammation in Alzheimer's disease mice. Novel heteropolysaccharide ATP50-3 inhibits proinflammatory factors, showing potential for AD treatment.

Neuroscience
Yu Q et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.131254
PubMed:
38565362

The investigation of thermal stability and GC-MS analysis of Acorus tatarinowii and Atractylodes lancea volatile oils treated by β cyclodextrin inclusion and Pickering emulsion technologies.

Chen ZY et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e25909
PubMed:
38439839

Polygala tenuifolia and Acorus tatarinowii in the treatment of Alzheimer's disease: a systematic review and meta-analysis.

Summary

Researchers evaluated the clinical efficacy and safety of a combination of two Chinese herbal formulas, PT and AT, for the treatment of Alzheimer's disease. The combination showed potential in improving cognition and functioning without increasing adverse events, but the quality of evidence is low.

Neuroscience
Zhang Y et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1268000
PubMed:
38283842

β-asarone improves cognitive impairment and alleviates autophagy in mice with vascular dementia via the cAMP/PKA/CREB pathway.

Summary

Researchers investigated the potential of β-asarone, a compound found in a plant called Acorus tatarinowii Schott, to reduce damage in cells deprived of oxygen and improve learning and memory. The study aims to determine if β-asarone can alleviate cerebral ischemic injury in mice with vascular dementia by acting through the cAMP/PKA/CREB pathway.

Neuroscience
Ning Z et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.155215
PubMed:
38039902

Acori Tatarinowii Rhizoma prevents the fluoxetine-induced multiple-drug resistance of Escherichia coli against antibiotics.

Wu J et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.155232
PubMed:
38006809

Multi-Chromosomal Mitochondrial Genome of Medicinal Plant Acorus tatarinowii (Acoraceae): Firstly Reported from Acorales Order.

Summary

Scientists analyzed the mitochondrial genome of Acorus tatarinowii, a traditional Chinese medicinal plant, revealing unique genes, complex chromosome structures, codon usage, repetitive sequences, and RNA editing sites. This enriches mitochondrial genome knowledge for Acoraceae and benefits other species as a reference.

Genetics
Tang J et al (2023).
Gene.
DOI:
10.1016/j.gene.2023.147847
PubMed:
37774807

Differential interference of copper with endophytic bacterial inoculation: Atrazine decontamination in Acorus tatarinowii and culture solution.

Wang X et al (2023).
Environ Pollut.
DOI:
10.1016/j.envpol.2023.122523
PubMed:
37683758

Neurovascular glial unit: A target of phytotherapy for cognitive impairments.

Summary

Herbal medicines may be useful for treating cognitive impairment in Alzheimer's disease and vascular dementia, by targeting dysfunction in the neurovascular glial unit.

Neuroscience
Chen L et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.155009
PubMed:
37573807

Herb pair of Polygala tenuifolia Willd and Acorus tatarinowii Schott decoction attenuates seizures and alleviates anxiety in mice: Evidence for modulating inflammation, alleviating oxidative stress and mediating GABA pathway.

Summary

PTAT decoction, a traditional medicine, showed significant antiepileptic and anxiolytic effects in mice through modulation of GABA neurotransmission and reduction of inflammation, suggesting potential as a natural treatment for epilepsy.

ImmunologyNeuroscience
Xie Y et al (2023).
Pak J Pharm Sci.
PubMed:
37530166

Domesticating aquatic plants in hydroponic systems to demonstrate and advance phytoremediation of the artificial sweetener acesulfame.

Ma X et al (2023).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2023.164806
PubMed:
37308013

Acorus tatarinowii Schott: A Review of Its Botany, Traditional Uses, Phytochemistry, and Pharmacology.

Summary

Schott is a medicinal plant used in empirical medicine for various diseases. It has many compounds that provide pharmacological effects, especially for brain and nervous system diseases.

Review Phytochemistry
Wang M et al (2023).
Molecules.
DOI:
10.3390/molecules28114525
PubMed:
37299001

Diversity and traditional knowledge of medicinal plants used by Shui people in Southwest China.

Liu S et al (2023).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-023-00594-4
PubMed:
37254191

β-asarone prolongs sleep via regulating the level of glutamate in the PVN.

Liu H et al (2023).
Biochem Biophys Res Commun.
DOI:
10.1016/j.bbrc.2023.05.010
PubMed:
37149985

Fumigant toxicity and behavioral alterations of six plant essential oils against the red fire ant (Solenopsis invicta Buren).

Fu J et al (2023).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-023-27329-y
PubMed:
37126171

Chemical composition and anticonvulsant activities of herb pair of Gastrodia elata Blume-Acorus tatarinowii Schott decoction on experimentally induced seizures in mice.

He X et al (2023).
Metab Brain Dis.
DOI:
10.1007/s11011-023-01211-9
PubMed:
37043151

Alpha-Asarone Ameliorates Neurological Dysfunction of Subarachnoid Hemorrhagic Rats in Both Acute and Recovery Phases via Regulating the CaMKII-Dependent Pathways.

Gao X et al (2023).
Transl Stroke Res.
DOI:
10.1007/s12975-023-01139-3
PubMed:
36781743

Essential oil of Acorus tatarinowii Schott inhibits neuroinflammation by suppressing NLRP3 inflammasome activation in 3 × Tg-AD transgenic mice.

Summary

Researchers studied the effects of Shi chang pu (SCP-oil) on the neuroinflammation of Alzheimer's disease. SCP-oil is the main active component of Acorus tatarinowii Schott, a herbal used for AD treatment in China. Results showed that SCP-oil reduced neuroinflammation in the brains of AD model rats by inhibiting the activation of microglia. This study suggests that SCP-oil may have potential as a therapeutic agent for AD.

ImmunologyNeurosciencePhytochemistry
Xu Z et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.154695
PubMed:
36774844

Therapeutic Potential of Active Components from Acorus gramineus and Acorus tatarinowii in Neurological Disorders and Their Application in Korean Medicine.

Review
Kim CJ et al (2022).
J Pharmacopuncture.
DOI:
10.3831/KPI.2022.25.4.326
PubMed:
36628348

Efficacy and safety of traditional Chinese medicine for the treatment of epilepsy: A updated meta-analysis of randomized controlled trials.

Summary

This study evaluated Traditional Chinese Medicine (TCM) for treating epilepsy. The efficacy and safety of TCM were tested. Results showed that TCM was effective and safe in treating epilepsy. This suggests that TCM could be a potential alternative treatment option for epilepsy patients.

Meta-Analysis Neuroscience
Lu H et al (2023).
Epilepsy Res.
DOI:
10.1016/j.eplepsyres.2022.107075
PubMed:
36603453

The Combination of Individual Herb of Mi-Jian-Chang-Pu Formula Exerts a Synergistic Effect in the Treatment of Ischemic Stroke in Rats.

Summary

Scientists studied the neuroprotective effects of the traditional Chinese medicine formula Mi-Jian-Chang-Pu on ischemic stroke (IS) using pharmacodynamics, pharmacokinetics, and metabolomics. They tested the individual herbs and major active components of the formula on rats with MCAO-induced brain damage. The study found that MJCPF had a synergistic effect, demonstrating small infarct volume and improved neural function. The levels of inflammatory factors were brought closer to normal. The formula also promoted drug absorption greater than other compounds tested. The findings suggest the scientific potential of TMC formulas in treating ischemic stroke.

CardiologyNeuroscience
Lu F et al (2022).
Oxid Med Cell Longev.
DOI:
10.1155/2022/9365760
PubMed:
36312894

Explore the Therapeutic Composition and Mechanism of Schisandra chinensis-Acorus tatarinowii Schott on Alzheimer's Disease by Using an Integrated Approach on Chemical Profile, Network Pharmacology, and UPLC-QTOF/MS-Based Metabolomics Analysis.

Summary

Researchers investigated the potential of traditional Chinese medicines Schisandra chinensis and Acorus tatarinowii Schott in Alzheimer's disease treatment and found them to have neuroprotective effects. Although the main anti-Alzheimer's compounds and functional mechanisms are unknown, clinical studies have proven their effectiveness. Further research could lead to a better understanding of these traditional medicines and their potential use in treating Alzheimer's disease.

Neuroscience
Chen J et al (2022).
Oxid Med Cell Longev.
DOI:
10.1155/2022/6362617
PubMed:
35860432

[Exploration on mechanism of Polygalae Radix and Acori Tatarinowii Rhizoma in treating Alzheimer's disease based on network pharmacology and experimental verification].

Summary

Scientists used network pharmacology, molecular docking, and animal tests to investigate the effects of Polygala tenuifolia and Acorus tatarinowii in treating Alzheimer's disease (AD). By analyzing active ingredients and targets of the traditional Chinese medicines, they identified core targets and pathways involved in AD. Mice with cognitive impairment were given the treatments, which improved learning and memory abilities and reduced neuron damage. The results suggest that P. tenuifolia and A. tatarinowii have potential for treating AD through multiple components, targets, and pathways.

Neuroscience
Su SJ et al (2022).
Zhongguo Zhong Yao Za Zhi.
DOI:
10.19540/j.cnki.cjcmm.20211216.707
PubMed:
35851129

Asymmetric interaction and concurrent remediation of copper and atrazine by Acorus tatarinowii in an aquatic system.

Wang X et al (2022).
J Hazard Mater.
DOI:
10.1016/j.jhazmat.2022.128888
PubMed:
35483262

Natural volatile oils derived from herbal medicines: A promising therapy way for treating depressive disorder.

Review
Zhang Y et al (2021).
Pharmacol Res.
DOI:
10.1016/j.phrs.2020.105376
PubMed:
33316383

Bioactivities of serotonin transporter mediate antidepressant effects of Acorus tatarinowii Schott.

Summary

A. tatarinowii Schott, a traditional Chinese medicine, has been used for centuries to treat neuropsychiatric and digestive disorders. Several studies have shown that it has antidepressant effects, but the mechanisms by which it works are still unknown.

Neuroscience
Zhang FH et al (2019).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2019.111967
PubMed:
31128148

Bioactive Nitrogenous Compounds from Acorus tatarinowii.

Feng XL et al (2016).
Magn Reson Chem.
DOI:
10.1002/mrc.4393
PubMed:
26640008

The effects of Acorus tatarinowii Schott on 5-HT concentrations, TPH2 and 5-HT1B expression in the dorsal raphe of exercised rats.

Summary

In a study, researchers investigated the effects of Acorus tatarinowii Schott, an herb used in traditional Chinese medicine, on treadmill running endurance in rats. They also looked at the levels of certain neurotransmitters and proteins in the rats' brains. The results showed that the rats who were given the herb had greater endurance and increased levels of serotonin, a neurotransmitter that can affect mood and behavior. The researchers suggest that Acorus tatarinowii Schott may have potential as an anti-fatigue supplement, but more research is needed to fully understand its effects on the central nervous system.

Neuroscience
Zhu M et al (2014).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2014.10.026
PubMed:
25456438

Phenylpropanes from Acorus tatarinowii.

Hu J and Feng X (2000).
Planta Med.
PubMed:
11105577