Scientists isolated secondary metabolites from Agrimonia pilosa for potential anti-colorectal cancer properties. Traditional medicine in Asia commonly uses it for enteritis and diarrhea treatment.
BHQJ is a traditional Chinese herbal remedy made from 7 plants. It effectively treats cough asthma and reduces airway inflammation.
Flavonoids from Agrimonia pilosa Ledeb improved insulin resistance and treated type 2 diabetes by reducing oxidative stress and inflammation, providing potential for natural and effective treatments.
Research explores dysbiosis in gut microbiota, genetic, immunological, and environmental factors in ulcerative colitis & Crohn's disease. Medicinal plants/compounds regulate NLRP3 inflammasome & reduce inflammation, offering treatment potential. Clinical validation and effective treatments development necessary.
The mixture extract from Ledeb (AP) and Bunge (SM) reduces pain and inflammation in arthritis through COX-1, COX-2, NF-κB, TNF-α, and IL-6 attenuation. Potential arthritis treatment.
Researchers examined the pain-relieving effects of Agrimonia pilosa Ledeb extract in mice. They found that oral administration of the extract (200 mg/kg) reduced pain as measured by various tests. The extract also reduced the nociceptive response to a substance that causes pain when injected into the spinal cord. The antinociceptive effect was blocked by a drug that blocks alpha-2 adrenergic receptors, but not by drugs that block opioid or serotonergic receptors. These findings suggest that Agrimonia pilosa Ledeb extract has pain-relieving properties, and that it may work by affecting alpha-2 adrenergic receptors.