Alchornea laxiflora

Ethnobotanical Studies

Clinical Trials

Salivary Fluoride Retention: A Comparative Analysis between Fluoride Containing Chewing Sticks and a Non Herbal Fluoridated Toothpaste.

Emeke U et al (2019).
J Contemp Dent Pract.
PubMed:
31204331

Studies

Alchornea laxiflora (Benth.) Pax & K. Hoffman extract protects against lead-induced neurodegeneration in cockerel chickens.

Summary

Study used (EaAL) leaves to counter lead-induced neurodegeneration in cockerels. EaAL reduced neuropathologies, restored myelin, outperforming Vitamin C. Exercise caution at 200 mg/kg.

Neuroscience
Esan OO et al (2024).
IBRO Neurosci Rep.
DOI:
10.1016/j.ibneur.2024.06.004
PubMed:
39006923

Integrating network pharmacology with molecular docking to rationalize the ethnomedicinal use of Alchornea laxiflora (Benth.) Pax & K. Hoffm. for efficient treatment of depression.

Summary

The study identified bioactive compounds in Alchornea laxiflora with potential antidepressant effects through molecular docking and network pharmacology. Key targets include SRC, EGFR, PIK3R1, AKT1, and MAPK1, suggesting a role in treating depression via PI3K-Akt and MAPK signaling pathways.

EthnobotanyNeuroscience
Jain NK et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1290398
PubMed:
38505421

Appraising the therapeutical potentials of Alchornea laxiflora (Benth.) Pax & K. Hoffm., an underexplored medicinal herb: A systematic review.

Jain NK et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.958453
PubMed:
36545314

Antibacterial and Antibiofilm Activity of Selected Medicinal Plant Leaf Extracts Against Pathogens Implicated in Poultry Diseases.

Olawuwo OS, Famuyide IM and McGaw LJ (2022).
Front Vet Sci.
DOI:
10.3389/fvets.2022.820304
PubMed:
35310417

Biosynthesis of zinc oxide nanoparticles using leaf extracts of Alchornea laxiflora and its tyrosinase inhibition and catalytic studies.

Ekennia A et al (2021).
Micron.
DOI:
10.1016/j.micron.2020.102964
PubMed:
33232905

Evaluation of botanical powders and extracts from Nigerian plants as protectants of maize grains against maize weevil, Sitophilus zeamais (Motschulsky) [Coleoptera: Curculionidae].

Ileke KD et al (2020).
Biocatal Agric Biotechnol.
DOI:
10.1016/j.bcab.2020.101702
PubMed:
32834890

Protective Effects of Crude Plant Extracts against Aminochrome-induced toxicity in Human Astrocytoma Cells: Implications for Parkinson's Disease.

Summary

The compound aminochrome can cause brain damage and a Parkinson's-like condition. The enzyme GSTM2 in brain cells can protect against aminochrome, but sometimes the protection is not strong enough. Some medicines made from plants may also protect against aminochrome damage.

Neuroscience
Ngoungoure VLN et al (2019).
Clin Pharmacol Transl Med.
PubMed:
31321384

Antibacterial activities of the methanol extracts of Albizia adianthifolia, Alchornea laxiflora, Laportea ovalifolia and three other Cameroonian plants against multi-drug resistant Gram-negative bacteria.

Tchinda CF et al (2017).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2016.01.033
PubMed:
28490970

Antimalarial, antiplasmodial and analgesic activities of root extract of Alchornea laxiflora.

Pain
Okokon JE, Augustine NB and Mohanakrishnan D (2017).
Pharm Biol.
DOI:
10.1080/13880209.2017.1285947
PubMed:
28183236

Cytotoxicity of methanol extracts of 10 Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines.

Cancer
Kuete V et al (2016).
BMC Complement Altern Med.
DOI:
10.1186/s12906-016-1253-3
PubMed:
27484842

Evaluation of Antibacterial and Antifungal Properties of Alchornea laxiflora (Benth.) Pax. & Hoffman.

Antimicrobial
Akinpelu DA et al (2015).
Evid Based Complement Alternat Med.
DOI:
10.1155/2015/684839
PubMed:
25688278

Antioxidant properties of extracts from Alchornea laxiflora (Benth) Pax and Hoffman.

Farombi EO et al (2003).
Phytother Res.
PubMed:
12916064

Bioactive chemical constituents from Alchornea laxiflora (benth) pax and hoffman.

Ogundipe OO et al (2001).
J Ethnopharmacol.
PubMed:
11274829