Alpinia galanga

Common Names: greater galangal

Ethnobotanical Studies

Clinical Trials

Effects of a ginger extract on knee pain in patients with osteoarthritis.

Altman RD and Marcussen KC (2001).
Arthritis Rheum.
PubMed:
11710709

Studies

New labdane diterpenoids from Alpinia galanga: A new type of GLP-1 secretagogues targeting the PKA-CREB and PI3K-Akt signaling axes.

Liu P et al (2024).
Arch Pharm (Weinheim).
DOI:
10.1002/ardp.202400383
PubMed:
39031533

Chemical Compositions and Fumigation Effects of Essential Oils Derived from Cardamom, Elettaria cardamomum (L.) Maton, and Galangal, Alpinia galanga (L.) Willd, against Red Flour Beetle, Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae).

Wanna R, Khaengkhan P and Bozdoğan H (2024).
Plants (Basel).
DOI:
10.3390/plants13131845
PubMed:
38999684

Encapsulation of Alpinia leaf essential oil in nanophytosome-embedded gel as novel strategy to treat periodontal infections: evaluation of antimicrobial effectiveness, pharmacokinetic, in vitro-ex vivo correlation and in silico studies.

Summary

Researchers created a new gel containing essential oil from tea tree leaves to fight gum disease. This could lead to more effective treatment options for periodontal infections in the future.

AntimicrobialPhytochemistry
Satapathy BS et al (2024).
J Microencapsul.
DOI:
10.1080/02652048.2024.2354234
PubMed:
38829223

Terpenoids from Alpinia galanga and their acetylcholinesterase inhibitory activity.

Summary

Researchers isolated new compounds from Zingiberaceae seeds, determining their structures and configurations. Some showed acetylcholinesterase inhibitory activity, potentially useful for neurological treatments.

Neuroscience
Zhou B et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2346269
PubMed:
38683975

In Vitro and In Vivo Anti-Inflammatory Activity of a Combination of Extracts from Cinnamomum zeylanicum, Alpinia galanga, and Withania somnifera used in Unani Medicine.

Immunology
Shiffa M et al (2024).
Altern Ther Health Med.
PubMed:
38581340

Harnessing nature's potential: Alpinia galanga methanolic extract mediated green synthesis of silver nanoparticle, characterization and evaluation of anti-neoplastic activity.

Ahmad E et al (2024).
Bioprocess Biosyst Eng.
DOI:
10.1007/s00449-024-02993-7
PubMed:
38509420

Ternary composite degradable plastics based on Alpinia galanga essential oil Pickering emulsion templates: A potential multifunctional active packaging.

Phytochemistry
Liang W et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.128580
PubMed:
38052283

Immunomodulatory effects and mechanisms of the extracts and secondary compounds of Zingiber and Alpinia species: a review.

Summary

Review analyzes immunomodulatory effects of and species on immune system via inflammation-related pathways. Extracts and secondary compounds show potential for clinical development in treating chronic inflammatory disorders.

Review Immunology
Yuandani et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1222195
PubMed:
37533631

Anti-inflammatory effect of Alpinia galanga extract on acute inflammatory cell model of peripheral blood mononuclear cells stimulated with TNF-α.

Immunology
Cahyono B, Suzery M and Amalina ND (2023).
Med Glas (Zenica).
DOI:
10.17392/1561-23
PubMed:
37300465

Computational investigation of phytochemicals identified from medicinal plant extracts against tuberculosis.

Ponnusamy N, Pillai G and Arumugam M (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2213341
PubMed:
37211911

Assessing the effect of Alpinia galanga extract on the treatment of SSRI-induced erectile dysfunction: A randomized triple-blind clinical trial.

Akbarzadeh F et al (2023).
Front Psychiatry.
DOI:
10.3389/fpsyt.2023.1105828
PubMed:
37143784

(1'S)-1'-Acetoxyeugenol Acetate Enhances Glucose-Stimulated Insulin Secretion.

Lee D et al (2023).
Plants (Basel).
DOI:
10.3390/plants12030579
PubMed:
36771665

In vitro antioxidant, anti-inflammatory, and anticancer activities of mixture Thai medicinal plants.

Immunology
Jongrungraungchok S et al (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-03862-8
PubMed:
36765341

Profiling of phytochemicals using LC-ESI-MS(2) , in vitro, in vivo characterization and cosmeceutical effects of Alpinia galanga (wild) extract loaded emulgel.

Phytochemistry
Khan MS, Adnan Q and Akhtar N (2023).
J Cosmet Dermatol.
DOI:
10.1111/jocd.15623
PubMed:
36718832

Pheophorbide-a as a Light-Triggered Liposomal Switch: For the Controlled Release of Alpinia galanga (A. galanga) Essential Oil and Its Stability, Antioxidant, and Antibacterial Activity Assessment.

Phytochemistry
Ge X et al (2023).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.2c07082
PubMed:
36629793

Lactating buffalos' productive performance, ruminal kinetics, nutrients digestibility and oxidative status as response to supplementing diets with alpinia galanga.

Khattab MSA et al (2022).
Anim Biotechnol.
DOI:
10.1080/10495398.2022.2146588
PubMed:
36394215

Evaluation of Phenolic Content Diversity along with Antioxidant/Pro-Oxidant, Glutathione Transferase Inhibition, and Cytotoxic Potential of Selected Commonly Used Plants.

Phytochemistry
Guneidy RA et al (2022).
Prev Nutr Food Sci.
DOI:
10.3746/pnf.2022.27.3.282
PubMed:
36313063

Stability Study of Alpinia galanga Constituents and Investigation of Their Membrane Permeability by ChemGPS-NP and the Parallel Artificial Membrane Permeability Assay.

Simon A et al (2022).
Pharmaceutics.
DOI:
10.3390/pharmaceutics14091967
PubMed:
36145715

Assessment of fresh Alpinia galanga (A. galanga) drying techniques for the chemical composition of essential oil and its antioxidant and biological activity.

Phytochemistry
Ge X et al (2022).
Food Chem.
DOI:
10.1016/j.foodchem.2022.133314
PubMed:
35636195

The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA(A) Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform.

Summary

A study investigated the binding of oil (AGO) and its compounds to GABA receptors in rat cortical membranes and computational modeling. Results show that AGO and methyl eugenol modulate GABA receptors, suggesting their anesthetic activity in mammals is associated with GABA receptor modulation. An oil-in-water nanoemulsion containing 20% w/w AGO (NE-AGO) was formulated and showed promising potential for human anesthesia with increased specific [H]muscimol binding and high tolerance by normal human cells.

Neuroscience
Khumpirapang N et al (2022).
Pharmaceutics.
DOI:
10.3390/pharmaceutics14030650
PubMed:
35336025

Journey of Alpinia galanga from kitchen spice to nutraceutical to folk medicine to nanomedicine.

Review
Ramanunny AK et al (2022).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.115144
PubMed:
35227783

Complete Chloroplast Genome Analysis of Two Important Medicinal Alpinia Species: Alpinia galanga and Alpinia kwangsiensis.

Genetics
Zhang Y et al (2021).
Front Plant Sci.
DOI:
10.3389/fpls.2021.705892
PubMed:
34975932

Isolation of new phytometabolites from Alpinia galanga willd rhizomes.

Sharma PK et al (2021).
Pak J Pharm Sci.
PubMed:
34799313

Combination of HRLC-MS with MPP and GNPS data analysis to identify major constituents of MtSK inhibitory Alpinia galanga extract.

Patrick M, Zhang Y and Calderón AI (2022).
Nat Prod Res.
DOI:
10.1080/14786419.2021.1916015
PubMed:
33951985

Pharmacological Effects of 1'-Acetoxychavicol Acetate, a Major Constituent in the Rhizomes of Alpinia galanga and Alpinia conchigera.

Review
Kojima-Yuasa A and Matsui-Yuasa I (2020).
J Med Food.
DOI:
10.1089/jmf.2019.4490
PubMed:
32069429