Ananas comosus

Common Names: pineapple

Ethnobotanical Studies

Clinical Trials

An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.

Colletti A et al (2024).
Nutrients.
DOI:
10.3390/nu16060784
PubMed:
38542694

Studies

Modulation of Growth and Mycotoxigenic Potential of Pineapple Fruitlet Core Rot Pathogens during In Vitro Interactions.

Vignassa M et al (2024).
Toxins (Basel).
DOI:
10.3390/toxins16080344
PubMed:
39195754

Characterization of Six Ampeloviruses Infecting Pineapple in Reunion Island Using a Combination of High-Throughput Sequencing Approaches.

Massé D et al (2024).
Viruses.
DOI:
10.3390/v16071146
PubMed:
39066307

In Vivo Glycemic Response of Fruit-Based Mango (Mangifera indica) and Pineapple (Ananas comosus) Bars in In Vitro and In Silico Enzyme Inhibitory Effects Studies.

Summary

Study showed mango and pineapple bars have low postprandial glycemic response, lower GI/GL, and inhibit α-amylase/α-glucosidase activity, promoting glycemic control and making them a healthy snack option.

Diabetes
Pérez-Beltrán YE et al (2024).
Foods.
DOI:
10.3390/foods13142258
PubMed:
39063344

Exploring the Therapeutic Potential of Bromelain: Applications, Benefits, and Mechanisms.

Review
Kansakar U et al (2024).
Nutrients.
DOI:
10.3390/nu16132060
PubMed:
38999808

Stable isotope dilution assay and HS-SPME-GCMS quantification of key aroma volatiles of Australian pineapple (Ananas comosus) cultivars.

George J et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2024.139956
PubMed:
38843713

Melanoloma viatrix Hendel (Diptera, Richardiidae): New Pest of Pineapple Plantations in the North of Brazil.

Adaime R et al (2024).
Neotrop Entomol.
DOI:
10.1007/s13744-024-01151-8
PubMed:
38833136

Employing fruit juices to hydrolyze edible bird's nest and enhance the antioxidant, anti-tyrosinase, and wound-healing activities of the hydrolysates.

Immunology
Nguyen TP et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e30879
PubMed:
38778992

Valorization applications of pineapple and papaya byproducts in food industry.

Review
Oliver-Simancas R et al (2024).
Compr Rev Food Sci Food Saf.
DOI:
10.1111/1541-4337.13359
PubMed:
38720571

Valorization of Pineapple (Ananas comosus) By-Products in Milk Coffee Beverage: Influence on Bioaccessibility of Phenolic Compounds.

Phytochemistry
Kocakaplan ZB et al (2024).
Plant Foods Hum Nutr.
DOI:
10.1007/s11130-024-01183-w
PubMed:
38696134

Bromelain as a natural anti-inflammatory drug: a systematic review.

Summary

Bromelain, a compound from pineapple, reduces inflammation by decreasing cytokine secretion and promoting healing. Useful for treating various diseases.

Review Immunology
Alves Nobre T et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2342553
PubMed:
38676413

Green synthesis of iron-doped graphene quantum dots: an efficient nanozyme for glucose sensing.

Li X et al (2024).
Nanoscale Horiz.
DOI:
10.1039/d4nh00024b
PubMed:
38568029

Anthelmintic screening of Bangladeshi medicinal plants and related phytochemicals using in vitro and in silico methods: An ethnobotanical perspective.

Summary

Researchers studied medicinal plants used by indigenous communities in Bangladesh for helminth infections. Discovering phytochemicals with anthelmintic activity could lead to new drugs to combat drug-resistant helminthiases in underdeveloped regions.

Ethnobotany
Khairuzzaman M et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118132
PubMed:
38565411

Current Uses of Bromelain in Children: A Narrative Review.

Review
Locci C, Chicconi E and Antonucci R (2024).
Children (Basel).
DOI:
10.3390/children11030377
PubMed:
38539412

Nutritional Composition and Therapeutic Potential of Pineapple Peel - A Comprehensive Review.

Farid A et al (2024).
Chem Biodivers.
DOI:
10.1002/cbdv.202400315
PubMed:
38484117

Effectiveness of Bacillus subtilis ANT01 and Rhizobium sp. 11B on the control of fusarium wilt in pineapple (Ananas comosus).

Adriano-Anaya L et al (2024).
PeerJ.
DOI:
10.7717/peerj.16871
PubMed:
38464753

Bromelain.

Review
(2024).
PubMed:
38381908

First Report of Leaf Spot of Pineapple (Ananas comosus (L.) Merr Caused by Neoscytalidium dimidiatum in Malaysia.

Afifah M et al (2024).
Plant Dis.
DOI:
10.1094/PDIS-09-23-1796-PDN
PubMed:
38254324

Utilization of Ananas comosus Crown Residue Husk as a Sustainable Strength Additive for EPR/LDPE Blend Composites.

Kumar J et al (2024).
ACS Omega.
DOI:
10.1021/acsomega.3c07697
PubMed:
38250353

Energy Partitioning and Latent Heat Flux Driving Factors of the CAM Plant Pineapple (Ananas comosus (L.) Merril) Grown in the South Subtropical China.

Liu Z et al (2023).
Plants (Basel).
DOI:
10.3390/plants13010021
PubMed:
38202329

Integrative Analysis of Metabolome and Transcriptome Provides Insights into the Mechanism of Flower Induction in Pineapple (Ananas comosus (L.) Merr.) by Ethephon.

Genetics
Lin W et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242417133
PubMed:
38138962

Bromelain regulates TRP channels to induce orofacial nociception relief in adult zebrafish.

Summary

Bromelain, found in pineapple, reduces orofacial pain in zebrafish by inhibiting TRP channels. This supports the use of bromelain as a pain reliever and shows its connection to TRP channel modulation.

Pain
Ribeiro SRL et al (2023).
Biochem Biophys Rep.
DOI:
10.1016/j.bbrep.2023.101598
PubMed:
38075000

Genome-Wide Identification and Characterization of Gibberellic Acid-Stimulated Arabidopsis Gene Family in Pineapple (Ananas comosus).

Genetics
Yang M et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242317063
PubMed:
38069384

Green Synthesis of Zinc Oxide Nanoparticles Using Ananas comosus Extract: Preparation, Characterization, and Antimicrobial Efficacy.

Summary

Scientists used AC extract to synthesize zinc oxide nanoparticles (ZnO-NPs). The NPs showed strong antimicrobial activity against , suggesting a potential solution for addressing associated infections.

Antimicrobial
Shah T, Surendar S and Singh S (2023).
Cureus.
DOI:
10.7759/cureus.47535
PubMed:
38021724

Genome Assembly and Microsatellite Marker Development Using Illumina and PacBio Sequencing in the Carex pumila (Cyperaceae) from Korea.

Genetics
Kim KR et al (2023).
Genes (Basel).
DOI:
10.3390/genes14112063
PubMed:
38003006

Solid-State Fermented Pineapple Peel: A Novel Food Ingredient with Antioxidant and Anti-Inflammatory Properties.

Immunology
Ortega-Hernández E et al (2023).
Foods.
DOI:
10.3390/foods12224162
PubMed:
38002219

Genome-wide identification of PEBP gene family in pineapple reveal its potential functions in flowering.

Summary

This study investigates the role of PEBP in regulating flowering time and morphogenesis in pineapple. It identifies 11 PEBP family members and explores their expression patterns. Overexpression of a specific gene resulted in early flowering, and potential flower regulators were identified. Valuable insights into pineapple flower development and guidance for future studies are provided.

Genetics
Zhang X et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1277436
PubMed:
37965004

Virtual screening, molecular docking, molecular dynamics, and MM-GBSA approaches identify prospective fructose-1,6-bisphosphatase inhibitors from pineapple for diabetes management.

Summary

Scientists discovered a potential antidiabetic compound in pineapple waste that inhibits the enzyme FBPase. More research is needed for efficacy and safety evaluation.

Diabetes
Hossain MS et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2276889
PubMed:
37916669

Draft genome of Lysinibacillus fusiformis PwPw_T2 isolated from Ananas comosus revealing acetic acid producing and xenobiotic degrading enzymes.

Summary

PwPw_T2 is an organism found in a deteriorating sample from Nigeria. It may have enzymes that produce acetic acid and break down harmful compounds. This could be useful in dealing with food waste and biotechnology.

Genetics
Adefiranye OO et al (2023).
Microbiol Resour Announc.
DOI:
10.1128/MRA.00753-23
PubMed:
37909746

Antibacterial Activity of Selected Fruit Juices against Multidrug-Resistant Bacterial Pathogens Involved in Urinary Tract and Sexually Transmitted Infections among Tribal Women in Madhya Pradesh, India.

Sharma P et al (2023).
J Pharmacopuncture.
DOI:
10.3831/KPI.2023.26.3.265
PubMed:
37799616

Effect of dielectric barrier discharge nonthermal plasma treatment on physicochemical, nutritional, and phytochemical quality attributes of pineapple [Ananas comosus (L.)] juice.

Phytochemistry
Pipliya S, Kumar S and Srivastav PP (2023).
J Food Sci.
DOI:
10.1111/1750-3841.16767
PubMed:
37755601

Phytochemical characterization, anti-diarrhoeal, analgesic, anti-inflammatory activities and toxicity profile of Ananas comosus (L.) Merr (pineapple) leaf in albino rats.

Summary

Researchers investigated the medicinal properties of pineapple leaf in treating various health issues. Understanding these properties can help in developing new treatments for diarrhoea, inflammation, pain, bacterial infections, and oedema.

ImmunologyPainPhytochemistry
Ugbogu EA et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117224
PubMed:
37748634

Towards a Multispectral Imaging System for Spatial Mapping of Chemical Composition in Fresh-Cut Pineapple (Ananas comosus).

Mollazade K, Hashim N and Zude-Sasse M (2023).
Foods.
DOI:
10.3390/foods12173243
PubMed:
37685176

Bromelain: a review of its mechanisms, pharmacological effects and potential applications.

Review
Kumar V et al (2023).
Food Funct.
DOI:
10.1039/d3fo01060k
PubMed:
37650738

Multiresponse optimization of the extrusion process for ready-to-eat snacks from pineapple byproducts and maize flour.

Vivar-Vera MA et al (2023).
J Food Sci.
DOI:
10.1111/1750-3841.16716
PubMed:
37548648

Modeling of the inactivation kinetics of aerobic mesophiles and yeasts and molds natural microbiota in nonthermal plasma-treated pineapple (Ananas comosus) juice.

Gastroenterology
Pipliya S, Kumar S and Srivastav PP (2023).
J Food Sci.
DOI:
10.1111/1750-3841.16721
PubMed:
37548638

High surface area activated carbon from a pineapple (ananas comosus) crown via microwave-ZnCl(2) activation for crystal violet and methylene blue dye removal: adsorption optimization and mechanism.

Hapiz A et al (2023).
Int J Phytoremediation.
DOI:
10.1080/15226514.2023.2241912
PubMed:
37545130

Identification of GA2ox Family Genes and Expression Analysis under Gibberellin Treatment in Pineapple (Ananas comosus (L.) Merr.).

Genetics
Zhu W et al (2023).
Plants (Basel).
DOI:
10.3390/plants12142673
PubMed:
37514287

Inhibition of carbohydrate hydrolyzing enzymes by a potential probiotic Levilactobacillus brevis RAMULAB49 isolated from fermented Ananas comosus.

Martiz RM et al (2023).
Front Microbiol.
DOI:
10.3389/fmicb.2023.1190105
PubMed:
37389344

Physical, Chemical, and Sensory Properties of a Turmeric-Fortified Pineapple Juice Beverage.

Sun X et al (2023).
Foods.
DOI:
10.3390/foods12122323
PubMed:
37372534

The Synergistic Mechanism of Photosynthesis and Antioxidant Metabolism between the Green and White Tissues of Ananas comosus var. bracteatus Chimeric Leaves.

Immunology
Lin D et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24119238
PubMed:
37298190

Bromelain supplementation and inflammatory markers: A systematic review of clinical trials.

Summary

Researchers examined the anti-inflammatory effects of bromelain, a natural enzyme from pineapple, in adults. It may be a promising alternative to reduce side effects of current anti-inflammatory drugs.

Review Immunology
Pereira IC et al (2023).
Clin Nutr ESPEN.
DOI:
10.1016/j.clnesp.2023.02.028
PubMed:
37202035

Efficacy and safety of bromelain: A systematic review and meta-analysis.

Review
Leelakanok N et al (2023).
Nutr Health.
DOI:
10.1177/02601060231173732
PubMed:
37157782

Genome-wide identification, phylogeny, and expression analysis of GRF transcription factors in pineapple (Ananas comosus).

Genetics
Yi W et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1159223
PubMed:
37123828

Integrated Metabolome and Transcriptome Analysis Reveals a Potential Mechanism for Water Accumulation Mediated Translucency in Pineapple (Ananas comosus (L.) Merr.) Fruit.

Genetics
Chen J et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24087199
PubMed:
37108358

Optimization of the pulp ratio of Ananas comosus, Citrullus lanatus and Psidium guajava and fermentation time in the production of a "fruit brandy".

Ambindei WA et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e14910
PubMed:
37064441

Function of ALA Content in Porphyrin Metabolism Regulation of Ananas comosus var. bracteatus.

Adjei MO et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24065274
PubMed:
36982348

Small Auxin Up RNA (SAUR) gene family identification and functional genes exploration during the floral organ and fruit developmental stages in pineapple (Ananas comosus L.) and its response to salinity and drought stresses.

Genetics
Zhang Y et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.124061
PubMed:
36933586

Molecular Docking and In Vitro Studies of Ochratoxin A (OTA) Biodetoxification Testing Three Endopeptidases.

Orozco-Cortés PC et al (2023).
Molecules.
DOI:
10.3390/molecules28052019
PubMed:
36903263

First Report of Colletotrichum fructicola Causing Fruit Rot and Leaf-Tip Dieback on Pineapple in Northern Thailand.

Armand A, Hyde KD and Jayawardena RS (2023).
Plants (Basel).
DOI:
10.3390/plants12040971
PubMed:
36840319

ACE2-Inhibitory Effects of Bromelain and Ficin in Colon Cancer Cells.

Summary

Bromelain and ficin are extracts from plants used for medical purposes. A study found that these extracts decreased the viability of colon cancer cells and induced apoptosis (cell death) in a concentration-dependent manner. The researchers also observed a decrease in the expression of ACE2 protein, which has potential implications for the treatment of COVID-19.

COVID-19
Pakbin B et al (2023).
Medicina (Kaunas).
DOI:
10.3390/medicina59020301
PubMed:
36837502

Genome-Wide Identification and Characterization of R2R3-MYB Provide Insight into Anthocyanin Biosynthesis Regulation Mechanism of Ananas comosus var. bracteatus.

Genetics
Yang W et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24043133
PubMed:
36834551

Review of the Aroma Chemistry of Pineapple (Ananas comosus).

Review
George J et al (2023).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.2c08546
PubMed:
36827381

Bromelain extraction using single stage nanofiltration membrane process.

Misran E, Idris A and Ya'akob H (2023).
J Food Sci Technol.
DOI:
10.1007/s13197-022-05618-7
PubMed:
36618058

Genetic and phenotype recovery of Ananas comosus var. MD2 in response to ionizing radiation.

Ma S et al (2023).
Sci Rep.
DOI:
10.1038/s41598-022-26745-3
PubMed:
36604574

Genetic Diversity of Viral Populations Associated with Ananas Germplasm and Improvement of Virus Diagnostic Protocols.

Larrea-Sarmiento AE et al (2022).
Pathogens.
DOI:
10.3390/pathogens11121470
PubMed:
36558805

A critical review on pineapple (Ananas comosus) wastes for water treatment, challenges and future prospects towards circular economy.

Review
Tran TV et al (2023).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2022.158817
PubMed:
36116641

Ananas comosus Peels Extract as a New Natural Cosmetic Ingredient: Oil-in-Water (O/W) Topical Nano Cream Stability and Safety Evaluation.

Yahya NA et al (2022).
Evid Based Complement Alternat Med.
DOI:
10.1155/2022/2915644
PubMed:
35600954

Bromelain, a Group of Pineapple Proteolytic Complex Enzymes (Ananas comosus) and Their Possible Therapeutic and Clinical Effects. A Summary.

Review
Varilla C et al (2021).
Foods.
DOI:
10.3390/foods10102249
PubMed:
34681298

Ananas comosus (L) Merrill (pineapple) fruit peel extract demonstrates antimalarial, anti-nociceptive and anti-inflammatory activities in experimental models.

ImmunologyPain
Ajayi AM et al (2022).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2021.114576
PubMed:
34461191

Pineapple (Ananas comosus L.) By-Products Valorization: Novel Bio Ingredients for Functional Foods.

Santos DI et al (2021).
Molecules.
DOI:
10.3390/molecules26113216
PubMed:
34072026

Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective.

Review
Chakraborty AJ et al (2021).
Life (Basel).
DOI:
10.3390/life11040317
PubMed:
33917319

Pineapple (Ananas comosus): A comprehensive review of nutritional values, volatile compounds, health benefits, and potential food products.

Review
Mohd Ali M et al (2020).
Food Res Int.
DOI:
10.1016/j.foodres.2020.109675
PubMed:
33233252

Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update.

Review
Taussig SJ and Batkin S (1988).
J Ethnopharmacol.
PubMed:
3287010