Anisodus acutangulus

Ethnobotanical Studies

Studies

A chromosome-level genome assembly of anesthetic drug-producing Anisodus acutangulus provides insights into its evolution and the biosynthesis of tropane alkaloids.

Summary

Researchers studied Tropane alkaloids in Anisodus acutangulus to understand its genome and biosynthesis pathways. This can lead to better manipulation of plants for anesthetic, analgesic, and spasmolytic effects.

Zhou W et al (2024).
Plant Commun.
PubMed:
37660252

Building Microbial Hosts for Heterologous Production of N-Methylpyrrolinium.

Ping Y et al (2019).
ACS Synth Biol.
PubMed:
30691267

Efficient biosynthesis of rare natural product scopolamine using E. coli cells expressing a S14P/K97A mutant of hyoscyamine 6β-hydroxylase AaH6H.

Cao YD et al (2015).
J Biotechnol.
PubMed:
26239231

Enhancing the production of tropane alkaloids in transgenic Anisodus acutangulus hairy root cultures by over-expressing tropinone reductase I and hyoscyamine-6β-hydroxylase.

Kai G et al (2012).
Mol Biosyst.
PubMed:
22955966

Functional identification of hyoscyamine 6β-hydroxylase from Anisodus acutangulus and overproduction of scopolamine in genetically-engineered Escherichia coli.

Kai G et al (2011).
Biotechnol Lett.
PubMed:
21380527

Molecular cloning and characterization of two tropinone reductases in Anisodus acutangulus and enhancement of tropane alkaloid production in AaTRI-transformed hairy roots.

Kai G et al (2009).
Biotechnol Appl Biochem.
PubMed:
19751215

Molecular characterization and expression analysis of two distinct putrescine N-methyltransferases from roots of Anisodus acutangulus.

Kai G et al (2009).
Physiol Plant.
PubMed:
19055544

Molecular cloning and characterization of a new cDNA encoding hyoscyamine 6beta-hydroxylase from roots of Anisodus acutangulus.

Kai G et al (2007).
J Biochem Mol Biol.
PubMed:
17927905