Antidesma bunius

Common Names: bignay

Ethnobotanical Studies

Studies

Integrating Computational Methods in Network Pharmacology and In Silico Screening to Uncover Multi-targeting Phytochemicals against Aberrant Protein Glycosylation in Lung Cancer.

Summary

This work explores the potential of certain plant compounds to interact with cancer-associated glycoproteins. The researchers used computational methods and docking approaches to identify phytochemicals from selected plants with drug-like properties. They created a network to analyze the interactions between the compounds and glycoproteins. Several compounds, including α-pinene, cyanomaclurin, genistein, and quercetin, showed potential in binding to known cancer biomarkers. The researchers also performed cytotoxicity assays on plant extracts, finding that certain extracts had growth inhibitory activity against lung cancer cells. This research could help further understand the cytotoxic activities of these plant compounds.

Cancer
Grijaldo SJB et al (2023).
ACS Omega.
DOI:
10.1021/acsomega.2c07542
PubMed:
37332828

Chemical constituents of Antidesma bunius aerial parts and the anti-AGEs activity of selected compounds.

Nguyen-Ngoc H et al (2022).
Phytochemistry.
DOI:
10.1016/j.phytochem.2022.113300
PubMed:
35798090

In vitro lipid-lowering properties of the fruits of two bignay [Antidesma bunius (L.) Spreng] cultivars as affected by maturity stage and thermal processing.

Crieta BRA et al (2021).
Food Chem (Oxf).
DOI:
10.1016/j.fochms.2021.100020
PubMed:
35415628

Acute oral toxicity assessment of ethanolic extracts of Antidesma bunius (L.) Spreng fruits in mice.

Muñoz MNM et al (2021).
Toxicol Rep.
DOI:
10.1016/j.toxrep.2021.06.010
PubMed:
34221900

Inhibitory Effect of Antidesma bunius Fruit Extract on Carbohydrate Digestive Enzymes Activity and Protein Glycation In Vitro.

Aksornchu P et al (2020).
Antioxidants (Basel).
DOI:
10.3390/antiox10010032
PubMed:
33396768

Anthocyanin-rich fraction from Thai berries interferes with the key steps of lipid digestion and cholesterol absorption.

Chamnansilpa N et al (2020).
Heliyon.
DOI:
10.1016/j.heliyon.2020.e05408
PubMed:
33204882

The potential of antioxidant-rich Maoberry (Antidesma bunius) extract on fat metabolism in liver tissues of rats fed a high-fat diet.

Ngamlerst C et al (2019).
BMC Complement Altern Med.
DOI:
10.1186/s12906-019-2716-0
PubMed:
31684925

Standard reference material (SRM) DNA barcode library approach for authenticating Antidesma bunius (L.) Spreng. (bignay) derived herbal medicinal products.

Genetics
Alfeche NKG et al (2019).
Food Addit Contam Part A Chem Anal Control Expo Risk Assess.
DOI:
10.1080/19440049.2019.1670868
PubMed:
31596175

Maoberry (Antidesma bunius) Improves Glucose Metabolism, Triglyceride Levels, and Splenic Lesions in High-Fat Diet-Induced Hypercholesterolemic Rats.

Udomkasemsab A et al (2019).
J Med Food.
DOI:
10.1089/jmf.2018.4203
PubMed:
30277837

Bitter Fruit: Inverse Associations Between PTC and Antidesma bunius Perception.

Wooding SP et al (2018).
Chem Senses.
DOI:
10.1093/chemse/bjy044
PubMed:
29982450

Taste Perception of Antidesma bunius Fruit and Its Relationships to Bitter Taste Receptor Gene Haplotypes.

Risso D et al (2018).
Chem Senses.
DOI:
10.1093/chemse/bjy037
PubMed:
29878085