Arnebia euchroma

Ethnobotanical Studies

Studies

A class of geranylquinol-derived polycyclic meroterpenoids from Arnebia euchroma against heart failure by reducing excessive autophagy and apoptosis in cardiomyocytes.

Summary

Scientists isolated new compounds from a plant, studied their structures and biosynthetic pathways, and found some had cardioprotective effects on heart cells by modulating cellular pathways. Important for drug development and understanding cardiac health.

Cardiology
Zhao LH et al (2024).
Bioorg Chem.
DOI:
10.1016/j.bioorg.2024.107691
PubMed:
39116524

A review on traditional medicine used for burn treatment.

Hoveidamanesh S et al (2024).
J Burn Care Res.
DOI:
10.1093/jbcr/irae152
PubMed:
39102254

Rapid identification and determination of adulteration in medicinal Arnebiae Radix by combining near infrared spectroscopy with chemometrics.

Li X et al (2024).
Spectrochim Acta A Mol Biomol Spectrosc.
DOI:
10.1016/j.saa.2024.124437
PubMed:
38772180

Harmony in nature: understanding the cultural and ecological aspects of plant use in Ladakh.

Angmo K et al (2024).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-024-00670-3
PubMed:
38486266

Inhibitory and preventive effects of Arnebia euchroma (Royle) Johnst. root extract on Streptococcus mutans and dental caries in rats.

Wu Z et al (2024).
BDJ Open.
DOI:
10.1038/s41405-024-00196-6
PubMed:
38431610

The healing effect of a mixture of Arnebia euchroma and animal fat on burn wounds in rats in comparison with sulfadiazine.

Dehkordi SH et al (2024).
J Wound Care.
DOI:
10.12968/jowc.2024.33.Sup2a.xiv
PubMed:
38324421

[Correlation between rhizosphere environment and content of medicinal components of Arnebia euchroma].

Zhang JZ et al (2023).
Zhongguo Zhong Yao Za Zhi.
DOI:
10.19540/j.cnki.cjcmm.20230725.101
PubMed:
38114209

[Effect of acetylalkannin from Arnebia euchroma on proliferation, migration, and invasion of human melanoma A375 cells].

Kang YY et al (2023).
Zhongguo Zhong Yao Za Zhi.
DOI:
10.19540/j.cnki.cjcmm.20230509.401
PubMed:
37802847

Euchronin A-F isolated from the Arnebia euchroma (Royle) Johnst. and their anti-proliferative activities in vitro.

Summary

Six new compounds called euchronin A-F and nine known compounds were discovered in Arnebia euchroma. Compounds 2 and 4 showed strong anti-proliferative activity against HaCaT cells, reducing cell viability to 38.83% and 68.44% at 25 μM concentration.

Cancer
Zhang ZP et al (2023).
J Nat Med.
DOI:
10.1007/s11418-023-01738-2
PubMed:
37658159

High-resolution neuraminidase inhibition profiling of Arnebia euchroma (Royle) I.M. Johnst. based on HR-MS and target isolation: An example study of anti-infectious constituents in traditional Chinese medicine.

Huang Y et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117074
PubMed:
37619859

Integrating human footprint with ensemble modelling identifies priority habitats for conservation: a case study in the distributional range of Arnebia euchroma, a vulnerable species.

Sofi II, Shah MA and Ganie AH (2023).
Environ Monit Assess.
DOI:
10.1007/s10661-023-11528-8
PubMed:
37395941

β-acetoxyisovalerylalkannin suppresses proliferation and induces ROS-based mitochondria-mediated apoptosis in human melanoma cells.

Xu F et al (2023).
J Asian Nat Prod Res.
DOI:
10.1080/10286020.2023.2221648
PubMed:
37310856

The discovery and characterization of AeHGO in the branching route from shikonin biosynthesis to shikonofuran in Arnebia euchroma.

Wang R et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1160571
PubMed:
37180378

The Potential of Medicinal Plants and Natural Products in the Treatment of Burns and Sunburn-A Review.

Review
Skowrońska W and Bazylko A (2023).
Pharmaceutics.
DOI:
10.3390/pharmaceutics15020633
PubMed:
36839954

Characterization of Arnebia euchroma PGT homologs involved in the biosynthesis of shikonin.

Wang S et al (2023).
Plant Physiol Biochem.
DOI:
10.1016/j.plaphy.2023.02.012
PubMed:
36780721

Shikonin potentiates therapeutic efficacy of oxaliplatin through reactive oxygen species-mediated intrinsic apoptosis and endoplasmic reticulum stress in oxaliplatin-resistant colorectal cancer cells.

Cancer
Zhang Z et al (2023).
Drug Dev Res.
DOI:
10.1002/ddr.22044
PubMed:
36779379

Screening and characterization estrogen receptor ligands from Arnebia euchroma (Royle) Johnst. via affinity ultrafiltration LC-MS and molecular docking.

Endocrinology
Zhu L et al (2022).
Front Plant Sci.
DOI:
10.3389/fpls.2022.1012553
PubMed:
36420029

Liver protection and hemostatic effects of medicinal plant Arnebia euchroma (Royle) I.M.Johnst extract in a rat model.

Ablat N et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.115739
PubMed:
36126784

Eight new arnebinol B-based meroterpenoids with planar chirality in the constrained 6/10/5 tricyclic skeleton from Arnebia euchroma and their cytotoxicities.

Yan HW et al (2022).
Bioorg Chem.
DOI:
10.1016/j.bioorg.2022.106091
PubMed:
36029650

Discrimination of Zicao Samples Based on DNA Barcoding and HPTLC Fingerprints, and Identification of (22E)-Ergosta-4,6,8(14),22-tetraen-3-one As a Marker Compound.

Genetics
Kretschmer N et al (2022).
Planta Med.
DOI:
10.1055/a-1855-1778
PubMed:
35868331

Current status and medicinal prominence of Arnebia euchroma (Ratanjot): A critically endangered plant of trans-Himalayan region.

Devi S et al (2022).
Recent Pat Biotechnol.
DOI:
10.2174/1872208316666220718154341
PubMed:
35850652

Relayed chromatography - Countercurrent chromatography in series with liquid chromatography for the separation of natural products.

Phytochemistry
Huang J, He JM and Mu Q (2022).
J Chromatogr A.
DOI:
10.1016/j.chroma.2022.463205
PubMed:
35709606

Comparing the Effectiveness of Arnebia euchroma with ClotrimazoleVaginal Cream for the Treatment of Vulvovaginal Candidiasis: A Randomized Controlled Triple-Blind Trial.

Mohammadi S et al (2022).
Iran J Nurs Midwifery Res.
DOI:
10.4103/ijnmr.ijnmr_330_20
PubMed:
35419264

Arnebia euchroma, a Plant Species of Cold Desert in the Himalayas, Harbors Beneficial Cultivable Endophytes in Roots and Leaves.

Jain R et al (2021).
Front Microbiol.
DOI:
10.3389/fmicb.2021.696667
PubMed:
34335527

Insights into the mechanism of Arnebia euchroma on leukemia via network pharmacology approach.

Cancer
Wang B et al (2020).
BMC Complement Med Ther.
DOI:
10.1186/s12906-020-03106-z
PubMed:
33109189

Anti-angiogenic effect of Shikonin in rheumatoid arthritis by downregulating PI3K/AKT and MAPKs signaling pathways.

Arthritis
Liu C et al (2020).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2020.113039
PubMed:
32497675

The Healing Effect of Arnebia Euchroma Ointment versus Silver Sulfadiazine on Burn Wounds in Rat.

Nasiri E et al (2015).
World J Plast Surg.
PubMed:
26284182