Artemisia absinthium

Common Names: absinth sagewort, common sagewort, absinth wormwood, absinthium

Ethnobotanical Studies

Studies

Total Mineral Content in Raw Materials of Ten Medicinal Plants from Roadside Biotopes of Voronezh Oblast.

Dyakova NA et al (2024).
Dokl Biol Sci.
DOI:
10.1134/S0012496624701126
PubMed:
39128956

Phytoconstituent Profiling and Antifungal Efficacy of Artemisia absinthium L.: Towards Sustainable Bio-Fungicide Development.

Summary

Study on Artemisia absinthium leaf extract shows potent antifungal activity against Fusarium oxysporum, Penicillium digitatum, and Alternaria solani. Fraction 4 contains 27 unique compounds, including Bruceine B, Guanidine, and Ethyl alpha-d-glucoside as strong inhibitors of key fungal enzymes. Potential natural alternative to synthetic fungicides.

Antimicrobial
Akhtar R and Kumar TS (2024).
Appl Biochem Biotechnol.
DOI:
10.1007/s12010-024-05030-1
PubMed:
39115786

Fabrication and Evaluation of a Soy Protein Isolate/Collagen/Sodium Alginate Multifunctional Bilayered Wound Dressing: Release of Cinnamaldehyde, Artemisia absinthium, and Oxygen.

Esmaeili J et al (2024).
ACS Appl Bio Mater.
DOI:
10.1021/acsabm.4c00611
PubMed:
39041410

Corrigendum: Essential Oils prime epigenetic and metabolomic changes in tomato defense against Fusarium oxysporum.

Soudani S et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2024.1443732
PubMed:
38978521

Essential Oil and Smoke Components of Artemisia absinthium and Hagenia abyssinica.

Summary

Scientists analyzed the essential oils and smoke components of and from Ethiopia. Compounds found may have medicinal benefits, providing potential new treatments or insights.

Phytochemistry
Kebie N and Sisay MA (2024).
Int J Food Sci.
DOI:
10.1155/2024/9949040
PubMed:
38938551

Effectiveness of some plant extracts in biocontrol of induced onion basal rot disease in greenhouse conditions.

Hegazy MGA et al (2024).
AMB Express.
DOI:
10.1186/s13568-024-01721-4
PubMed:
38874641

Antifeedant, antifungal and nematicidal compounds from the endophyte Stemphylium solani isolated from wormwood.

Summary

Scientists studied a fungal endophyte from Artemisia absinthium for biopesticidal properties. Isolate Aa22 showed antifungal, insect antifeedant, and nematicidal activities. Three compounds were isolated, including a new one, with potential for biopesticide development.

Antimicrobial
Diaz CE et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-64467-w
PubMed:
38867066

Analyzing The Chemical Constituents and In Vitro Biological Effects of Extracts Artemisia absinthium L. Extracts Obtained Using Different Methodologies and Solvents.

Yagi S et al (2024).
Chem Biodivers.
DOI:
10.1002/cbdv.202400893
PubMed:
38779862

Plant cultural indicators of forest resources from the Himalayan high mountains: implications for improving agricultural resilience, subsistence, and forest restoration.

Haq SM et al (2024).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-024-00685-w
PubMed:
38659048

Effects of Artemisia absinthium on broiler chicken coccidiosis: a systematic review and meta-analysis.

Review
Hezil N et al (2024).
Avian Pathol.
DOI:
10.1080/03079457.2024.2342882
PubMed:
38616734

Chemical Composition and Biocontrol Activity of Different Essential Oils against Soil-Borne Fungal Pathogens.

Akdeniz Y and Kesimci TG (2024).
Plant Pathol J.
DOI:
10.5423/PPJ.OA.01.2024.0002
PubMed:
38606448

Exploring anti-inflammatory and antioxidant-related quality markers of Artemisia absinthium L. based on spectrum-effect relationship.

Immunology
Wubuli A et al (2024).
Phytochem Anal.
DOI:
10.1002/pca.3350
PubMed:
38591190

In vivo assessment of the antiparasitic effects of Allium sativum L. and Artemisia absinthium L. against gastrointestinal parasites in swine from low-input farms.

Băieş MH et al (2024).
BMC Vet Res.
DOI:
10.1186/s12917-024-03983-3
PubMed:
38561770

Antibacterial Effect of Eight Essential Oils against Bacteria Implicated in Bovine Mastitis and Characterization of Primary Action Mode of Thymus capitatus Essential Oil.

Phytochemistry
Aouadhi C et al (2024).
Antibiotics (Basel).
DOI:
10.3390/antibiotics13030237
PubMed:
38534672

Oviposition Deterrent Activity of Some Wild Plants for Adult Females of Chrysomya albiceps with Medical and Veterinary Importance.

Abu El-Ghiet UM et al (2024).
Pak J Biol Sci.
DOI:
10.3923/pjbs.2024.8.17
PubMed:
38413393

Chemical composition and toxicity of Moroccan mentha spicata and Artemisia absinthium essential oils against Pthorimaea operculella, the potato moth.

Mahboub F et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2320740
PubMed:
38403974

Nanoemulsion and nanoencapsulation of a hydroethanolic extract of Nettle (Urtica dioica) and Wormwood (Artemisia absinthium): comparison of antibacterial and anticancer activity.

Summary

This study investigated the effects of nanoemulsion and nanoencapsulation of Nettle and Wormwood extracts on antibacterial and anticancer activity. The formulations showed increased activity, especially CCNW, making them potentially useful in food and pharmaceutical industries.

Cancer
Rahmani Z et al (2024).
Front Chem.
DOI:
10.3389/fchem.2024.1266573
PubMed:
38292020

Biological Potential and Therapeutic Effectiveness of Artemetin from Traditional to Modern Medicine: An Update on Pharmacological Activities and Analytical Aspects.

Patel K and Patel DK (2024).
Recent Adv Antiinfect Drug Discov.
DOI:
10.2174/0127724344266027231215105620
PubMed:
38275071

Antipyretic activity of the hydro-alcoholic extract of Artemisia absinthium L. as a standalone and as an adjuvant with barley water against yeast-induced pyrexia in albino Wistar rats.

Bhat MM et al (2023).
J Complement Integr Med.
DOI:
10.1515/jcim-2023-0307
PubMed:
38109312

Larvicidal, pupalicidal and adulticidal effects of Artemisia absinthium L. against dengue vector Aedes aegypti (Diptera: Culicidae) in Jazan region, K.S.A.

Areshi S et al (2023).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2023.103853
PubMed:
38020224

Total Flavonoids in Artemisia absinthium L. and Evaluation of Its Anticancer Activity.

Summary

The study used ultrasound-assisted enzymatic hydrolysis to improve the yield of flavonoids in L. They identified Cynaroside and Astragalin as potential anticancer compounds that inhibit cervical cancer growth by regulating signaling proteins. These compounds also induce apoptosis by increasing ROS levels.

CancerPhytochemistry
He M et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242216348
PubMed:
38003540

In Vitro Assessment of the Antidiabetic and Anti-Inflammatory Potential of Artemisia absinthium, Artemisia vulgaris and Trigonella foenum-graecum Extracts Processed Using Membrane Technologies.

Summary

This study analyzed the antidiabetic and anti-inflammatory potential of certain herbs. The extracts from showed high inhibitory activity on α-amylase and LOX, while extracts from showed increased α-amylase inhibition activity and extracts from showed pronounced LOX inhibition activity.

DiabetesImmunology
Neagu E et al (2023).
Molecules.
DOI:
10.3390/molecules28207156
PubMed:
37894635

The anticancer and antibacterial potential of bioactive secondary metabolites derived From bacterial endophytes in association with Artemisia absinthium.

Summary

Researchers explored the diversity of bacteria in the medicinal plant A. absinthium and discovered that P. aeruginosa SD01 has potent antimicrobial and anticancer properties, specifically against S. aureus and MRSA. This study identified several bioactive secondary metabolites that could be used in drug discovery.

Cancer
Damavandi MS, Shojaei H and Esfahani BN (2023).
Sci Rep.
DOI:
10.1038/s41598-023-45910-w
PubMed:
37891400

Secretome profiling of Artemisia absinthium extract-loaded polymeric nanoparticle-treated MCF-7 and MDA-MB-231 revealed perturbation in microtubule assembly and cell migration.

Kauser S et al (2023).
Front Oncol.
DOI:
10.3389/fonc.2023.1209168
PubMed:
37719007

The aqueous extract of Artemisia Absinthium L. stimulates HO-1/MT-1/Cyp450 signaling pathway via oxidative stress regulation induced by aluminium oxide nanoparticles (α and γ) animal model.

Immunology
Karami E et al (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-04121-6
PubMed:
37670294

The Role of Plant-Derived Natural Products in the Management of Inflammatory Bowel Disease-What Is the Clinical Evidence So Far?

Summary

Researchers reviewed the use of plant-derived natural products, such as Curcumin and Mastiha, in the management of inflammatory bowel diseases (IBD). These products have antioxidant, anti-inflammatory, and immunomodulatory properties, and may offer an alternative or complementary treatment to standard medications.

Review Immunology
Davila MM and Papada E (2023).
Life (Basel).
DOI:
10.3390/life13081703
PubMed:
37629560

Development of Nanosuspension of Artemisia absinthium Extract as Novel Drug Delivery System to Enhance Its Bioavailability and Hepatoprotective Potential.

Jahan N et al (2023).
J Funct Biomater.
DOI:
10.3390/jfb14080433
PubMed:
37623677

New Evidence for Artemisia absinthium as an Alternative to Classical Antibiotics: Chemical Analysis of Phenolic Compounds, Screening for Antimicrobial Activity.

Summary

This study evaluated the antimicrobial activity of methanol extracts of an herb, finding broad-spectrum antibacterial and antifungal activity. It identified 90 compounds, including new ones, and showed the safety of the extracts. This suggests the potential use of the herb as an alternative to antibiotics for addressing bacterial resistance.

AntimicrobialPhytochemistry
Liu Z et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms241512044
PubMed:
37569422

Pre-clinical toxicity assessment of Artemisia absinthium extract-loaded polymeric nanoparticles associated with their oral administration.

Kauser S et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1196842
PubMed:
37492095

Umbelliprenin induces autophagy and apoptosis while inhibits cancer cell stemness in pancreatic cancer cells.

Summary

Umbelliprenin, a compound found in Artemisia absinthium L., has demonstrated its ability to induce apoptosis and exhibit antitumor effects in different types of cancers. However, its potential role in treating human pancreatic cancer remains unclear. Investigating the antitumor effect of umbelliprenin specifically in pancreatic cancer could provide valuable insights into potential therapeutic options for this challenging disease.

Cancer
Wang H et al (2023).
Cancer Med.
DOI:
10.1002/cam4.6170
PubMed:
37409635

Structure-based virtual screening of anti-breast cancer compounds from Artemisia absinthium-insights through molecular docking, pharmacokinetics, and molecular dynamic simulations.

Summary

A study investigated the potential use of a natural breast cancer medicine with low side effects. Researchers extracted and identified compounds from leaf powder using advanced technology. They then tested the compounds' ability to bind to breast cancer receptors and found that one compound, 3',4',5,7-Tetrahydroxyisoflavanone (THIF), showed stronger binding than standard drugs. Additional analysis showed that THIF had good drugability and lower toxicity. Molecular dynamics simulation revealed structural changes during protein-ligand interaction. Overall, this research suggests that THIF has potential as an anti-breast cancer drug. (Words: 79)

Cancer
Gnanaselvan S, Yadav SA and Manoharan SP (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2212805
PubMed:
37194295

Gastroprotective effect of Artemisia absinthium L.: A medicinal plant used in the treatment of digestive disorders.

Boeing T et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116488
PubMed:
37059247

Keeping Healthy in Your Skin-Plants and Fungi Used by Indigenous Himalayan Communities to Treat Dermatological Ailments.

Dermatology
Haq SM et al (2023).
Plants (Basel).
DOI:
10.3390/plants12071575
PubMed:
37050200

Two in vitro assays and UHPLC-HRMS quantification of targeted metabolomic profiles for proof of concept of the anthelmintic activity of medicinal plants and their association with polyphenols.

Meza Ocampos G et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116453
PubMed:
37019160

Artemisia absinthium extract attenuates the quinolinic acid-induced cell injury in OLN-93 cells.

Rashidi R et al (2023).
Curr Drug Discov Technol.
DOI:
10.2174/1570163820666230330105331
PubMed:
36998142

The In Vitro Anticoccidial Activity of Some Herbal Extracts against Eimeria spp. Oocysts Isolated from Piglets.

Bǎieş MH et al (2023).
Pathogens.
DOI:
10.3390/pathogens12020258
PubMed:
36839530

The effects of Artemisia absinthium L. on scopolamine-induced learning and memory impairment and brain tissue oxidative damage in adult rats.

Summary

Researchers investigated how Lactobacillus (L.) affects memory impairment caused by scopolamine in rats. They also looked at its impact on oxidative damage to brain tissue. The study's findings could reveal the potential of Lactobacillus as a preventive and therapeutic measure for memory disorders.

Neuroscience
Rahimi M et al (2023).
Avicenna J Phytomed.
DOI:
10.22038/AJP.2022.62851.2991
PubMed:
36698740

Removal of Pb ions using green Co(3)O(4) nanoparticles: Simulation, modeling, adsorption, and biological studies.

Singh S et al (2023).
Environ Res.
DOI:
10.1016/j.envres.2023.115335
PubMed:
36693464

Applicability of new sustainable and efficient green metal-based nanoparticles for removal of Cr(VI): Adsorption anti-microbial, and DFT studies.

Antimicrobial
Singh S et al (2023).
Environ Pollut.
DOI:
10.1016/j.envpol.2023.121105
PubMed:
36682618

Rumen fermentation, methane concentration, and blood metabolites of cattle receiving dietetical phytobiotic and cobalt (II) chloride.

Ryazanov V et al (2022).
Vet World.
DOI:
10.14202/vetworld.2022.2551-2557
PubMed:
36590132

Species-Specific Plant-Derived Nanoparticle Characteristics.

Viršilė A et al (2022).
Plants (Basel).
DOI:
10.3390/plants11223139
PubMed:
36432868

Spectral analysis and antibacterial effect of cold methanolic extract of Artemisia absinthium L.

Sultan MH and Moni SS (2022).
Braz J Biol.
DOI:
10.1590/1519-6984.264869
PubMed:
36417615

Phytochemical Profiling, Antioxidant, Antimicrobial and Cholinesterase Inhibitory Effects of Essential Oils Isolated from the Leaves of Artemisia scoparia and Artemisia absinthium.

AntimicrobialPhytochemistry
Khan FA et al (2022).
Pharmaceuticals (Basel).
DOI:
10.3390/ph15101221
PubMed:
36297333

Potential Ameliorative Effect of Artemisia Absinthium Supplement against Sodium Fluoride-Induced Prostatic Toxicity in Rats.

Shakir Saleh H, Yahya Kraidi S and Ali Mahdi W (2022).
Arch Razi Inst.
DOI:
10.22092/ARI.2022.357126.1982
PubMed:
36284952

In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity.

Genetics
Mazzari ALDA et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.826395
PubMed:
36278236

Combination of LC-Q-TOF-MS/MS, network pharmacology, and nanoemulsion approaches identifies active compounds of two Artemisia species responsible for tackling early diabetes-related metabolic complications in the liver.

Diabetes
Moulahoum H et al (2022).
Phytochem Anal.
DOI:
10.1002/pca.3159
PubMed:
35795911

In vitro evaluation of the effects of methanolic plant extracts on the embryonation rate of Ascaridia galli eggs.

Poulopoulou I et al (2022).
Vet Res Commun.
DOI:
10.1007/s11259-022-09958-9
PubMed:
35727416

Artemisia absinthium L. Aqueous and Ethyl Acetate Extracts: Antioxidant Effect and Potential Activity In Vitro and In Vivo against Pancreatic α-Amylase and Intestinal α-Glucosidase.

Gastroenterology
Hbika A et al (2022).
Pharmaceutics.
DOI:
10.3390/pharmaceutics14030481
PubMed:
35335858

Protective effect of Artemisia absinthium on 6-hydroxydopamine-induced toxicity in SH-SY5Y cell line.

Summary

This study explored the potential of to protect against the loss of dopaminergic neurons associated with Parkinson's disease. The researchers conducted experiments using SH-SY5Y cells and found that had neuroprotective and antioxidant effects on 6-OHDA-induced toxicity. These findings suggest that may have potential therapeutic benefits for individuals living with Parkinson's disease.

Neuroscience
Rashidi R et al (2021).
Avicenna J Phytomed.
PubMed:
34046320

Effect of Artemisia absinthium ethanolic extract on oxidative stress markers and the TLR4, S100A4, Bax and Bcl-2 genes expression in the kidney of STZ-induced diabetic rats.

DiabetesGenetics
Bagheri F et al (2020).
Horm Mol Biol Clin Investig.
DOI:
10.1515/hmbci-2020-0028
PubMed:
33079704

Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Wormwood (Artemisia absinthium).

Review
Batiha GE et al (2020).
Antibiotics (Basel).
DOI:
10.3390/antibiotics9060353
PubMed:
32585887

Herbal and plant therapy in patients with inflammatory bowel disease.

Review Immunology
Triantafyllidi A et al (2015).
Ann Gastroenterol.
PubMed:
25830661

Artemisia absinthium and Artemisia vulgaris: a comparative study of infusion polysaccharides.

Corrêa-Ferreira ML, Noleto GR and Oliveira Petkowicz CL (2014).
Carbohydr Polym.
DOI:
10.1016/j.carbpol.2013.10.096
PubMed:
24507342

Absinthe--a review.

Review
Lachenmeier DW et al (2006).
Crit Rev Food Sci Nutr.
PubMed:
16891209