Artemisia afra

Ethnobotanical Studies

Studies

Identification of South African Plant-Based Bioactive Compounds as Potential Inhibitors against the SARS-CoV-2 Receptor.

Summary

Researchers studied South African medicinal plants for bioactive compounds inhibiting SARS-CoV-2 binding to ACE2 receptors. Identified promising compounds like sesaminol glucoside could lead to new phytotherapeutics.

Mkolo NM et al (2024).
Pharmaceuticals (Basel).
PubMed:
39065672

An O-methylflavone from Artemisia afra kills non-replicating hypoxic Mycobacterium tuberculosis.

Kellogg JJ et al (2024).
J Ethnopharmacol.
PubMed:
38944359

An updated inventory of medicinal and ritual plants of southern Africa.

Cornelius SF and Van Wyk BE (2024).
J Ethnopharmacol.
PubMed:
38763369

Differential Anti-Fibrotic and Remodeling Responses of Human Dermal Fibroblasts to Artemisia sp., Artemisinin, and Its Derivatives.

Weathers P et al (2024).
Molecules.
PubMed:
38731597

Comparative Bioactive Compounds and Mineral Properties of South African and Lesotho Artemisia afra (Jacq.) Genotypes.

Rafiri M, Sedibe MM and Dikane GMH (2024).
Plants (Basel).
PubMed:
38674538

The Indiscriminate Chemical Makeup of Secondary Metabolites Derived from Endophytes Harvested from Aloe barbadensis Miller in South Africa's Limpopo Region.

Nchabeleng MM, Fonkui TY and Ezekiel G (2024).
Molecules.
PubMed:
38542933

Assessing the Efficiency of Antimicrobial Plant Extracts from Artemisia afra and Eucalyptus globulus as Coatings for Textiles.

Summary

Study examined plant extracts as textile coatings, showing varying antimicrobial effectiveness. Hexanoic extract was most potent against bacteria, methanolic extract showed antibacterial properties but reduced post-laundering. Findings inform use of plant extracts in textile antimicrobial coatings.

Nortjie E et al (2024).
Plants (Basel).
PubMed:
38498494

Correction: Suh Nchang et al. Knowledge about Asymptomatic Malaria and Acceptability of Using Artemisia afra Tea among Health Care Workers (HCWs) in Yaoundé, Cameroon: A Cross-Sectional Survey. Int. J. Environ. Res. Public Health 2023, 20, 6309.

Suh Nchang A et al (2024).
Int J Environ Res Public Health.
PubMed:
38248575

Extractives from Artemisia afra with Anti-Bacterial and Anti-Fungal Properties.

Summary

Scientists isolated secondary metabolites from the roots of and tested their anti-fungal, anti-bacterial, and cytotoxicity activities. They discovered eight new compounds with potential medicinal uses, including compounds with anti-fungal and anti-bacterial properties. These compounds showed no toxicity in Vero cells.

Molokoane TL et al (2023).
Plants (Basel).
PubMed:
37836110

Knowledge about Asymptomatic Malaria and Acceptability of Using Artemisia afra Tea among Health Care Workers (HCWs) in Yaoundé, Cameroon: A Cross-Sectional Survey.

Suh Nchang A et al (2023).
Int J Environ Res Public Health.
PubMed:
37444156

Secondary Metabolites Isolated from Artemisia afra and Artemisia annua and Their Anti-Malarial, Anti-Inflammatory and Immunomodulating Properties-Pharmacokinetics and Pharmacodynamics: A Review.

Summary

This review summarizes the phytochemical composition and pharmacological properties of two species from the Asteraceae family, including their potential as anti-malarial and anti-inflammatory agents. The toxicity of these plants and other genus species is also discussed.

Review Immunology
Shinyuy LM et al (2023).
Metabolites.
PubMed:
37233654

Expression of the Fab enzymes (Fab I and Fab Z) from Plasmodium falciparum after exposure to Artemisia afra plant extracts and drugs screening.

Kane NF et al (2023).
J Parasit Dis.
PubMed:
36910309

Artemisia afra and Artemisia annua Extracts Have Bactericidal Activity against Mycobacterium tuberculosis in Physiologically Relevant Carbon Sources and Hypoxia.

Kiani BH et al (2023).
Pathogens.
PubMed:
36839499

Anti-Salmonella activity of plant species in the Benin republic: Artemisia afra and Detarium senegalense with promising in vitro and in vivo activities.

Amoussa AMO et al (2023).
Biomed Pharmacother.
PubMed:
36521244

Geographical and seasonal phytochemical variation of Artemisia afra Jacq. ex Willd.

Olivier D, van der Kooy F and Gerber M (2023).
Phytochem Anal.
PubMed:
36464634

Bioprospecting of Essential Oil-Bearing Plants: Rapid Screening of Volatile Organic Compounds Using Headspace Bubble-in-Drop Single-Drop Microextraction for Gas Chromatography Analysis.

Letseka TE et al (2022).
Plants (Basel).
PubMed:
36297773

Artemisia extracts differ from artemisinin effects on human hepatic CYP450s 2B6 and 3A4 in vitro.

Kane NF et al (2022).
J Ethnopharmacol.
PubMed:
35934190

Antiviral activity of medicinal plant-derived products against SARS-CoV-2.

Summary

Extracts and phytocompounds from medicinal plants have been shown to have antiviral activity against SARS-CoV-2. These plant products impede the virus from attaching to host cells and prevent its multiplication inside the cell. They also have an immunomodulatory effect by controlling the release of cytokines associated with SARS-CoV-2 infections. These findings demonstrate the potential of plant-based treatments for COVID-19.

de Oliveira JR et al (2022).
Exp Biol Med (Maywood).
PubMed:
35894129

Antibacterial Effects of Artemisia afra Leaf Crude Extract Against Some Selected Multi-Antibiotic Resistant Clinical Pathogens.

Haile AB and Jiru TM (2022).
Ethiop J Health Sci.
PubMed:
35813676

Traditional uses of wild and tended plants in maintaining ecosystem services in agricultural landscapes of the Eastern Cape Province in South Africa.

Maroyi A et al (2022).
J Ethnobiol Ethnomed.
PubMed:
35292046

Traditionally used polyherbals in a southern African therapeutic context.

Review
Van Vuuren SF, Motlhatlego KE and Netshia V (2022).
J Ethnopharmacol.
PubMed:
35017037

Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites.

Ashraf K et al (2021).
Life Sci Alliance.
PubMed:
34857648

Validating a sensitive LCMS method for the quantitation of artemisinin in Artemisia spp. including material used in retracted clinical trials.

Lee BJ et al (2022).
J Pharm Biomed Anal.
PubMed:
34763209

Artemisia annua and Artemisia afra extracts exhibit strong bactericidal activity against Mycobacterium tuberculosis.

Martini MC et al (2020).
J Ethnopharmacol.
PubMed:
32730878

Ne pas jeter le bébé avec l'eau de son bain. A propos d'Artemisia afra.

Pays JF et al (2019).
Bull Soc Pathol Exot.
PubMed:
31825186

Artemisia afra, a controversial herbal remedy or a treasure trove of new drugs?

Review
du Toit A and van der Kooy F (2019).
J Ethnopharmacol.
PubMed:
31376515

Pulmonary effects and disposition of luteolin and Artemisia afra extracts in isolated perfused lungs.

Joel Mjiqiza S, Abraham Syce J and Chibuzo Obikeze K (2013).
J Ethnopharmacol.
PubMed:
23920249