Common Names: carambola
A study on Averrhoa carambola fruit found it rich in nutrients and vitamins, with higher antioxidant activity and potential health benefits. It could be a valuable source of nutraceutical compounds.
This study investigated the effects of Averrhoa carambola L. fruit polyphenols (ACFP) on obesity-related complications in mice. ACFP showed protective effects against hyperlipidemia, hepatic steatosis, and hyperglycemia. The mechanisms of action underlying these effects were also examined.
Star fruit toxicity can cause both kidney and neurological problems, especially in individuals with prior renal impairment. A review of ten case series and 28 case reports found that acute oxalate nephropathy with tubulointerstitial nephritis or tubular necrosis was common. Neurotoxicity manifestations ranged from hiccups to status epilepticus. The main substances causing nephrotoxicity and neurotoxicity were oxalate and caramboxin, which inhibits GABA binding and activates glutamatergic receptors. Early detection and renal replacement therapy can improve outcomes. Animal studies shed light on the underlying mechanisms of toxicity.