Berberis vulgaris

Common Names: berbéris vulgaire, common barberry, épine-vinette, European barberry, vinetteier

Ethnobotanical Studies

Studies

Effects of Berberis vulgaris, and its active constituent berberine on cytochrome P450: a review.

Review
Bathaei P, Imenshahidi M and Hosseinzadeh H (2024).
Naunyn Schmiedebergs Arch Pharmacol.
DOI:
10.1007/s00210-024-03326-x
PubMed:
39141022

Pharmacological Potential of Three Berberine-Containing Plant Extracts Obtained from Berberis vulgaris L., Mahonia aquifolium (Pursh) Nutt., and Phellodendron amurense Rupr.

Ciorîță A et al (2024).
Biomedicines.
DOI:
10.3390/biomedicines12061339
PubMed:
38927546

Berberine mitigates diclofenac-induced intestinal mucosal mechanical barrier dysfunction through the restoration of autophagy by inhibiting exosome-mediated lncRNA H19.

Gastroenterology
He R et al (2024).
Inflammopharmacology.
DOI:
10.1007/s10787-024-01487-y
PubMed:
38758516

Berberis vulgaris L. Root Extract as a Multi-Target Chemopreventive Agent against Colon Cancer Causing Apoptosis in Human Colon Adenocarcinoma Cell Lines.

Summary

BVR root extract from L. () showed promising chemopreventive effects against colon cancer cells, inducing programmed cell death and altering gene expression related to apoptosis. BVR also demonstrated antioxidant and anti-inflammatory properties. Consider using BVR as a comprehensive chemopreventive agent in colorectal cancer.

CancerGastroenterology
Och A et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25094786
PubMed:
38732003

Herbal Treatments for Obesity: A Review.

Summary

TL;DR: Obesity is linked to many health issues. FDA-approved drugs have side effects. Herbal plants like Berberis vulgaris and Aloe vera are effective and safe alternatives. Consider using them for cost-effective and novel treatments.

Obesity
Gasmi A et al (2024).
Curr Med Chem.
DOI:
10.2174/0109298673287491240315055726
PubMed:
38509683

Berberine: A natural modulator of immune cells in multiple sclerosis.

Summary

Berberine may have immunomodulatory effects on T cell subsets and dendritic cells, impacting cytokines involved in multiple sclerosis. Research suggests potential therapeutic benefits for treating MS.

Review Neuroscience
Yazdanpanah E et al (2024).
Immun Inflamm Dis.
DOI:
10.1002/iid3.1213
PubMed:
38477663

Development of halochromic electrospun labels for non-invasive shelf life assessment of rainbow trout (Oncorhynchus mykiss): Incorporation of barberry anthocyanin extract in protein-based smart packaging.

Aliakbari FS et al (2024).
Food Sci Technol Int.
DOI:
10.1177/10820132231219779
PubMed:
38374619

Anti-inflammatory, antioxidant, and immunomodulatory effects of Berberis vulgaris and its constituent berberine, experimental and clinical, a review.

Summary

Review on Berberis vulgaris (barberry) and berberine highlights their potential as anti-inflammatory and antioxidant agents. They inhibit pro-inflammatory cytokines, increase anti-inflammatory cytokines, scavenge free radicals, and reduce oxidative stress. They show promise in various diseases, but further research is required for optimal use and safety.

Review Immunology
Shakeri F et al (2024).
Phytother Res.
DOI:
10.1002/ptr.8077
PubMed:
38358731

Effect of berberine on cognitive function and β-amyloid precursor protein in Alzheimer's disease models: a systematic review and meta-analysis.

Summary

Study evaluates the effects of berberine on Alzheimer's disease. Results show that it improves cognitive function and reduces the expression of amyloid precursor protein, suggesting potential neuroprotective effects. (40 words, 232 characters)

Neuroscience
Liu JY et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1301102
PubMed:
38293672

Recombination in the wheat stem rust pathogen mediated by an indigenous barberry species in Spain.

Rodriguez-Algaba J et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1322406
PubMed:
38293628

Effects of Berberis vulgaris fruit extract on oxidative stress status in the kidney and liver of diabetic rats.

Summary

Research investigated the effects of fruit extract on oxidative stress in diabetic rats. Understanding oxidative stress in diabetes can help us develop strategies for prevention and treatment.

DiabetesImmunology
Ahmadi M, Hadjzadeh MA and Rajaei Z (2024).
J Complement Integr Med.
DOI:
10.1515/jcim-2023-0163
PubMed:
38282343

Fruits of Wild-Grown Shrubs for Health Nutrition.

Review
Stabnikova O, Stabnikov V and Paredes-López O (2024).
Plant Foods Hum Nutr.
DOI:
10.1007/s11130-024-01144-3
PubMed:
38280176

Chitosan/alginate scaffold enhanced with Berberis vulgaris extract for osteocyte differentiation of ovine fetal stem cells.

Soltani L et al (2024).
Cell Biochem Funct.
DOI:
10.1002/cbf.3924
PubMed:
38269507

Berberis vulgaris L. extract supplementation exerts regulatory effects on the lifespan and healthspan of Drosophila through its antioxidant activity depending on the sex.

Immunology
Golubev D et al (2023).
Biogerontology.
DOI:
10.1007/s10522-023-10083-6
PubMed:
38150086

Heterogeneous Cellular Response of Primary and Metastatic Human Gastric Adenocarcinoma Cell Lines to Magnoflorine and Its Additive Interaction with Docetaxel.

Gastroenterology
Grabarska A et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242115511
PubMed:
37958494

Novel Core-shell Bioceramic Silica-Berberis vulgaris: Synthesis and Characterization.

Chawshli MF and Hamad SK (2023).
Cell Mol Biol (Noisy-le-grand).
DOI:
10.14715/cmb/2023.69.10.39
PubMed:
37953570

Evaluation of berberine nanoparticles as a strategy to modulate acetylcholinesterase activity.

Summary

Berberine-loaded solid dispersions (SD) show potential as inhibitors of acetylcholinesterase enzyme (AChE) for neurodegenerative disease treatment, with improved water solubility and cytotoxic effects on tumoral cells. The berberine SD also demonstrated no cytotoxicity/genotoxicity in testing, suggesting it could be a safe option.

Neuroscience
Leimann FV et al (2023).
Food Res Int.
DOI:
10.1016/j.foodres.2023.113295
PubMed:
37803607

Facile extraction of berberine from different plants, separation, and identification by thin-layer chromatography, high-performance liquid chromatography, and biological evaluation against Leishmaniosis.

Phytochemistry
Alam SD et al (2023).
J Sep Sci.
DOI:
10.1002/jssc.202300582
PubMed:
37675810

Evaluation of berberine pellet effect on clinical recovery time in COVID-19 outpatients: A pilot clinical trial.

Summary

Berberine, a medicinal compound with analgesic, anti-asthmatic, anti-inflammatory, and antiviral properties, was studied for its effect on COVID-19 outpatients. Understanding its impact could provide insights into treating respiratory distress syndrome caused by severe COVID-19.

COVID-19
Omidvar Tehrani S et al (2023).
Avicenna J Phytomed.
DOI:
10.22038/AJP.2022.21539
PubMed:
37654997

Evaluation of the Effect of Barberry Root (Berberis Vulgaris) on the Prevention of Metabolic Syndrome Caused by Atypical Antipsychotic Drugs in Patients with Schizophrenia: A Three-Blind Placebo-Controlled Clinical Trial.

Summary

This study aimed to investigate the potential of barberry root extract in preventing metabolic syndrome caused by antipsychotic drugs in patients with schizophrenia. However, the results showed that the extract was not effective in controlling the effects of these drugs on metabolic syndrome.

Neuroscience
Rostami H et al (2023).
Iran J Psychiatry.
DOI:
10.18502/ijps.v18i3.13015
PubMed:
37575603

Evaluation of the Antioxidant and Anti-Lipoxygenase Activity of Berberis vulgaris L. Leaves, Fruits, and Stem and Their LC MS/MS Polyphenolic Profile.

Immunology
Och A et al (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12071467
PubMed:
37508005

Species-specific influence of powdery mildew mycelium on the efficiency of PM accumulation by urban greenery.

Przybysz A et al (2023).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-023-28371-6
PubMed:
37351744

Flowers and Inflorescences of Selected Medicinal Plants as a Source of Triterpenoids and Phytosterols.

Edorh Tossa P et al (2023).
Plants (Basel).
DOI:
10.3390/plants12091838
PubMed:
37176893

Natural Anticancer Agents: Their Therapeutic Potential, Challenges,s and Promising Outcomes.

Summary

Plant-based drugs show potential for treating various types of cancer, with compounds like curcumin and quercetin having extensive research and promising results. This study reviews several plants and their key compounds with anticancer activity, highlighting potential clinical candidates.

Cancer
Tauro S et al (2023).
Curr Med Chem.
DOI:
10.2174/0929867330666230502113150
PubMed:
37138435

Magnoflorine from Berberis vulgaris Roots-Impact on Hippocampal Neurons in Mice after Short-Term Exposure.

Szalak R et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24087166
PubMed:
37108329

Inclusion of Berberis vulgaris leaf in the diet of fattening lambs: Effects on performance, nutrient intake, rumen fermentation, and carcass traits.

Vaghar Seyedin SM et al (2023).
J Anim Sci.
DOI:
10.1093/jas/skad131
PubMed:
37105718

Evaluation of Therapeutic Potential of Selected Plant-Derived Homeopathic Medicines for their Action against Cervical Cancer.

Cancer
Singh T et al (2023).
Homeopathy.
DOI:
10.1055/s-0042-1756436
PubMed:
36858077

The Berberis vulgaris L. extract berberine exerts its anti-oxidant effects to ameliorate cholesterol overloading-induced cell apoptosis in the primary mice hepatocytes: an in vitro study.

Ye Z et al (2022).
In Vitro Cell Dev Biol Anim.
DOI:
10.1007/s11626-022-00737-z
PubMed:
36481977

Simple and Effective Derivatization of Amino Acids with 1-Fluoro-2-nitro-4-(trifluoromethyl)benzene in a Microwave Reactor for Determination of Free Amino Acids in Kombucha Beverages.

Jastrzębska A et al (2022).
Materials (Basel).
DOI:
10.3390/ma15207365
PubMed:
36295430

Interaction of Different Drying Methods and Storage on Appearance, Surface Structure, Energy, and Quality of Berberis vulgaris var. asperma.

Talebzadeh SL et al (2022).
Foods.
DOI:
10.3390/foods11193003
PubMed:
36230079

Pharmacokinetic of berberine, the main constituent of Berberis vulgaris L.: A comprehensive review.

Review
Khoshandam A, Imenshahidi M and Hosseinzadeh H (2022).
Phytother Res.
DOI:
10.1002/ptr.7589
PubMed:
36221815

Neuroprotective Effect of Root Extracts of Berberis Vulgaris (Barberry) on Oxidative Stress on SH-SY5Y Cells.

Summary

The study investigated the protective effects of barberry root extract and berberine against neuronal damage caused by oxidative stress. They tested this using a human cell line and found that both substances were able to protect against damage induced by hydrogen peroxide. These findings suggest that barberry root extract and berberine could potentially be used to treat neurodegenerative disorders like Alzheimer's disease.

Neuroscience
Rad ES et al (2022).
J Pharmacopuncture.
DOI:
10.3831/KPI.2022.25.3.
PubMed:
36186093

Antioxidant, Antibacterial, and Antifungal Activities of the Ethanolic Extract Obtained from Berberis vulgaris Roots and Leaves.

Antimicrobial
El-Zahar KM et al (2022).
Molecules.
DOI:
10.3390/molecules27186114
PubMed:
36144846

Partial substitution of alfalfa hay by Berberis vulgaris leaf modulated the growth performance, meat quality and antioxidant status of fattening lambs.

Seyedin SMV et al (2022).
Vet Med Sci.
DOI:
10.1002/vms3.934
PubMed:
36112758

Metabolic profile and antioxidant capacity of five Berberis leaves species: A comprehensive study to determine their potential as natural food or ingredient.

Nova-Baza D et al (2022).
Food Res Int.
DOI:
10.1016/j.foodres.2022.111642
PubMed:
36076377

Berbamine and thymoquinone exert protective effects against immune-mediated liver injury via NF-κB dependent pathway.

Kathem SH, Abdulsahib WK and Zalzala MH (2022).
Front Vet Sci.
DOI:
10.3389/fvets.2022.960981
PubMed:
35958317

Consumption of oils and anthocyanins may positively modulate PPAR-γ expression in chronic noncommunicable diseases: A systematic review.

Review
Brum ISDC et al (2022).
Nutr Res.
DOI:
10.1016/j.nutres.2022.06.004
PubMed:
35905655

The effects of Berberis vulgaris L. root extract on the opiate withdrawal syndrome and psychological factors: a randomized double-blind clinical trial.

Dabaghzadeh F et al (2021).
J Basic Clin Physiol Pharmacol.
DOI:
10.1515/jbcpp-2020-0327
PubMed:
34147041

A review on pain-relieving activity of berberine.

Review Pain
Hashemzaei M and Rezaee R (2021).
Phytother Res.
DOI:
10.1002/ptr.6984
PubMed:
33340158

The effects of Berberis vulgaris L. and Berberis aristata L. in metabolic syndrome patients: a systematic and meta-analysis study.

Roshanravan B et al (2020).
Arch Physiol Biochem.
DOI:
10.1080/13813455.2020.1828482
PubMed:
33040642

Berberine and barberry (Berberis vulgaris): A clinical review.

Review
Imenshahidi M and Hosseinzadeh H (2019).
Phytother Res.
DOI:
10.1002/ptr.6252
PubMed:
30637820

Berberis vulgaris: specifications and traditional uses.

Review
Rahimi-Madiseh M et al (2017).
Iran J Basic Med Sci.
DOI:
10.22038/IJBMS.2017.8690
PubMed:
28656092

Berberis vulgaris for cardiovascular disorders: a scoping literature review.

Review Cardiology
Abushouk AI, Salem AMA and Abdel-Daim MM (2017).
Iran J Basic Med Sci.
DOI:
10.22038/IJBMS.2017.8674
PubMed:
28656085

Berberine and Its Role in Chronic Disease.

Review
Cicero AF and Baggioni A (2016).
Adv Exp Med Biol.
PubMed:
27671811

Berberis Vulgaris and Berberine: An Update Review.

Review
Imenshahidi M and Hosseinzadeh H (2016).
Phytother Res.
DOI:
10.1002/ptr.5693
PubMed:
27528198