Calotropis procera

Common Names: mudar, roostertree

Ethnobotanical Studies

Studies

Facile synthesis of silver nanoparticles using Calotropis procera leaves: unraveling biological and electrochemical potentials.

Nagime PV et al (2024).
Discov Nano.
DOI:
10.1186/s11671-024-04090-w
PubMed:
39227530

In Silico Analysis of Calotropis procera-Derived Phytochemicals Targeting 3CL Proteoase of SARS-CoV-2.

Summary

Scientists studied phytochemicals from Calotropis Procera as potential drugs against the main protease (3CLp) of SARS-CoV-2. 11 phytochemicals showed promise with strong binding affinity and reactivity. These compounds could be developed as effective drugs against COVID-19.

COVID-19
Shafique T et al (2024).
Mol Biotechnol.
DOI:
10.1007/s12033-024-01253-z
PubMed:
39177861

In Silico Screening of Phytocompounds from West African Traditional Medicine and Molecular Docking Targeting Dengue Virus Protein NS2B/NS3.

Kantagba YMK et al (2024).
Stud Health Technol Inform.
DOI:
10.3233/SHTI240492
PubMed:
39176820

Investigation of bioactive phytochemical compounds of the Ethiopian medicinal plant using GC-MS and FTIR.

Summary

Study on medicinal plant extracts for treating warts showed presence of various bioactive compounds with anti-bacterial, analgesic, anti-inflammatory properties. Effective against gram-positive bacteria. Traditional therapy uses this plant for wart treatment.

Phytochemistry
Adem Endris Y, Abdu KY and Abate SG (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e34687
PubMed:
39170564

Bio-bleaching of ankara pulp with xylanase-producing bacterial consortium for sustainable handmade paper production.

Rajput M et al (2024).
Curr Res Microb Sci.
DOI:
10.1016/j.crmicr.2024.100262
PubMed:
39148722

Tapping the potential of Calotropis procera hairy roots for cardiac glycosides production and their identification using UHPLC/QTOF-MS.

Summary

Scientists established hairy root cultures from different explants of a plant using a specific strain. High transformation frequency achieved. Identified 10 cardiac glycosides in hairy root extracts. Valuable for production of cardiac glycosides and future research.

CardiologyPhytochemistry
Djerdjouri A et al (2024).
3 Biotech.
DOI:
10.1007/s13205-024-04035-1
PubMed:
39144068

Diesel removal in non-aqueous phase by fibres from Calotropis procera: kinetic, isothermal and sorption potential evaluation.

de França MRG et al (2024).
Environ Technol.
DOI:
10.1080/09593330.2024.2375005
PubMed:
38972300

Calotropis procera and the Pharmacological Properties of Its Aqueous Leaf Extract: A Review.

Review
Habeeb A, Ramesh S and Shanmugam R (2024).
Cureus.
DOI:
10.7759/cureus.60354
PubMed:
38883127

Effectiveness of some plant extracts in biocontrol of induced onion basal rot disease in greenhouse conditions.

Hegazy MGA et al (2024).
AMB Express.
DOI:
10.1186/s13568-024-01721-4
PubMed:
38874641

Angiogenic protein profiling, phytochemical screening and in silico anti-cancer targets validation of stem, leaves, fruit, and seeds of Calotropis procera in human liver and breast cancer cell lines.

Summary

Researchers studied C. procera for potential anticancer properties. Extracts showed antiangiogenic and anticancer capabilities with minimal side effects. Identifying novel targets for liver cancer treatment. Important for developing innovative medications.

CancerPhytochemistry
Khan MF et al (2024).
Environ Res.
DOI:
10.1016/j.envres.2024.119180
PubMed:
38795948

Ethnobotanical assessment of antidiabetic medicinal plants in District Karak, Pakistan.

Summary

Study examines use of plant-based traditional medicines for treating diabetes in Karak, Pakistan. Results could lead to new treatments for diabetes, which is a major global health issue.

DiabetesEthnobotany
Nazar A et al (2024).
BMC Complement Med Ther.
DOI:
10.1186/s12906-024-04462-w
PubMed:
38658923

Assessment of bioremediation potential of Calotropis procera and Nerium oleander for sustainable management of vehicular released metals in roadside soils.

Anjum S et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-58897-9
PubMed:
38637588

Phytochemicals analysis and aflatoxin B(1) detoxification potential of leaves extract of Moringa oleifera and Calotropis procera.

Nisar N et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2342003
PubMed:
38625875

Calotropis procera extract inhibits prostate cancer through regulation of autophagy.

Summary

Calotropis procera leaf extract inhibits prostate cancer cell viability by regulating autophagy and ROS levels, making it a potential alternative therapy with fewer side effects.

Cancer
Singh P et al (2024).
J Cell Mol Med.
DOI:
10.1111/jcmm.18050
PubMed:
38400579

Calotropis procera: A double edged sword against glioblastoma, inhibiting glioblastoma cell line growth by targeting histone deacetylases (HDAC) and angiogenesis.

Saleh Alanazi SH et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e24406
PubMed:
38304784

Anti-Leishmania major activity of Calotropis procera extract by increasing ROS production and upregulating TNF-α, IFN-γ and iNOS mRNA expression under in vitro conditions.

Genetics
Amani S et al (2024).
Trop Med Health.
DOI:
10.1186/s41182-024-00578-4
PubMed:
38303082

Polyphenols-Rich Extract of Calotropis procera Alone and in Combination with Trichoderma Culture Filtrate for Biocontrol of Cantaloupe Wilt and Root Rot Fungi.

Nofal AM et al (2023).
Molecules.
DOI:
10.3390/molecules29010139
PubMed:
38202721

Assessment of Plant Growth-Promoting Parameters of Endophytes Isolated from Calotropis procera and Their Performance Under Irrigated and Non-irrigated Conditions.

Jaiswal S, Ojha A and Mishra SK (2023).
Curr Microbiol.
DOI:
10.1007/s00284-023-03570-z
PubMed:
38147132

Endophytic Alkalotolerant Plant Growth-Promoting Bacteria Render Maize (Zea mays L.) Growth Under Alkaline Stress.

Kar S et al (2023).
Curr Microbiol.
DOI:
10.1007/s00284-023-03557-w
PubMed:
38117393

Preliminary data on cytotoxicity and functional group assessment of a herb-mineral combination against colorectal carcinoma cell line.

Gastroenterology
Jayakumar R et al (2023).
J Complement Integr Med.
DOI:
10.1515/jcim-2023-0221
PubMed:
38016708

Bacterial endophytes inhabiting desert plants provide protection against seed rot caused by Fusarium verticillioides and promote growth in maize.

Dinango VN et al (2024).
Pest Manag Sci.
DOI:
10.1002/ps.7850
PubMed:
37886813

Structural and functional traits underlying the capacity of Calotropis procera to face different stress conditions.

Iqbal U, Hameed M and Ahmad F (2023).
Plant Physiol Biochem.
DOI:
10.1016/j.plaphy.2023.107992
PubMed:
37688901

Calotropis procera accumulates Uzarigenin and Calotropagenin in response to environmental lighting and drought.

Hassan S et al (2023).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2023.103622
PubMed:
36950364

First report of triterpenes pathway in Calotropis procera revealed to accumulate beta-amyrin.

Hassan S et al (2022).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2022.02.055
PubMed:
35844368

Calotropis Procera Induced Caspase-Dependent Apoptosis and Impaired Akt/mTOR Signaling in 4T1 Breast Cancer Cells.

Cancer
Rabelo ACS et al (2022).
Anticancer Agents Med Chem.
DOI:
10.2174/1871520622666220608122154
PubMed:
35676853

Induction of Catharanthus roseus Secondary Metabolites When Calotropis procera Was Used as Bio-Stimulant.

Abeed AHA et al (2021).
Plants (Basel).
DOI:
10.3390/plants10081623
PubMed:
34451668

Light/heat effects on RNA editing in chloroplast NADH-plastoquinone oxidoreductase subunit 2 (ndhB) gene of Calotropis (Calotropis procera).

Genetics
Ramadan AM et al (2020).
J Genet Eng Biotechnol.
DOI:
10.1186/s43141-020-00064-4
PubMed:
32915330

Calotropis procera attenuates chronic unpredictable mild stress-induced depression in experimental animals.

Neuroscience
Garabadu D, Srivastava N and Murti Y (2019).
Metab Brain Dis.
DOI:
10.1007/s11011-019-00471-8
PubMed:
31346860