Carica papaya

Common Names: papaya, pawpaw

Ethnobotanical Studies

Clinical Trials

Fermented Carica papaya and Morinda citrifolia as Perspective Food Supplements for the Treatment of Post-COVID Symptoms: Randomized Placebo-Controlled Clinical Laboratory Study.

Fermented food supplements improved clinical symptoms, reduced inflammation, and increased immune function in COVID-19 patients, according to a study with 188 participants. The findings suggest that fermented tropical fruits may effectively decrease post-COVID symptoms through immune-modulating, redox balancing, and pro-energy mechanisms.

Kharaeva Z et al (2022).
Nutrients.
PubMed:
35684003

Effectiveness of dried Carica papaya seeds against human intestinal parasitosis: a pilot study.

Okeniyi JA et al (2007).
J Med Food.
PubMed:
17472487

Studies

Pesticide Exposure in the Cultivation of Carica papaya L. and Capsicum annuum L. in Rural Areas of Oaxaca, Mexico.

Bernardino-Hernández HU et al (2024).
Int J Environ Res Public Health.
PubMed:
39200670

Research on the Isolation of Endophytic Fungi from Papaya and the Prevention of Colletotrichum gloeosporioides.

Lv J et al (2024).
J Fungi (Basel).
PubMed:
39194876

First report of Erwinia papayae associated with papaya mushy canker disease in Guam.

Delorm JG and Dulla GFJ (2024).
Plant Dis.
PubMed:
39115951

Hybrid nanoparticles combining nanoselenium-mediated Carica papaya extract and trimethyl chitosan for combating clinical multidrug-resistant bacteria.

Gamal AA et al (2024).
Int J Biol Macromol.
PubMed:
39089553

Essential oils inhibiting Alternaria alternata and Colletotrichum gloeosporioides: a review.

Review
Radice M et al (2024).
Nat Prod Res.
PubMed:
39082305

Exploring the extraction, functional properties, and industrial applications of papain from Carica papaya.

Review
Choudhary R et al (2024).
J Sci Food Agric.
PubMed:
39077990

Carica Papaya leaf-infused metal oxide nanocomposite: a green approach towards water treatment and antibacterial applications.

Aswini R et al (2024).
Environ Geochem Health.
PubMed:
39060662

First Report of Colletotrichum gigasporum causing Anthracnose of chili pepper in South Korea.

Choi HW et al (2024).
Plant Dis.
PubMed:
39054605

Differential expression of microRNAs in response to Papaya ringspot virus infection in differentially responding genotypes of papaya (Carica papaya L.) and its wild relative.

Patil BL and Tripathi S (2024).
Front Plant Sci.
PubMed:
38966149

Isolation and characterization of plant-derived exosome-like nanoparticles from Carica papaya L. fruit and their potential as anti-inflammatory agent.

Iriawati I et al (2024).
PLoS One.
PubMed:
38959219

Environmental profiling of gold nanoparticles by flavonoids fractionalization from carrica papaya leaf extract for photocatalytic debasement of organic contaminants and it's cyto-toxic analysis.

Summary

Carica papaya leaf extract used to create eco-friendly gold nanoparticles with efficient photocatalytic and anticancer properties, demonstrating potential for environmental remediation and medical applications.

Sathya TA et al (2024).
Environ Res.
PubMed:
38942259

Carica papaya L. sex chromosome review and physical mapping of the serk 2, svp-like and mdar 4 sequences.

Summary

Researchers mapped serk 2, svp-like, and mdar 4 genes in Carica papaya, confirming diploidy and identifying sex chromosomes. This procedure can be applied to other genes, aiding in cytogenetic mapping and providing new insights into chromosome structure and evolution.

Dornela AF et al (2024).
Sci Rep.
PubMed:
38937542

Phytochemical Study of the Anthelminthic Potential of Guadeloupean Plant Biodiversity.

Summary

Researchers investigated the anthelmintic potential of plant extracts on gastrointestinal parasites in ruminants. Plants with high polyphenolic content were tested for their effectiveness against Rudolphi. This study aims to find alternative treatments for parasite infections in animals.

Cabald T et al (2024).
Pharmaceuticals (Basel).
PubMed:
38931441

Complete genome sequence and phylogenetic analysis of a newly discovered fusagra-like virus infecting Carica papaya in Ecuador.

Cornejo-Franco JF et al (2024).
Arch Virol.
PubMed:
38902586

Valorization of pawpaw (Carica papaya L.) leaves as a source of polyphenols by ionic liquid-based microwave-assisted extraction: Comparison with other extraction methods and bioactivity evaluation.

Cao D et al (2024).
Food Chem X.
PubMed:
38855093

Antifungal activity of Carica papaya fruit extract against Microsporum canis: in vitro and in vivo study.

Summary

Study tested () fruit extract effectiveness against scalp ringworm fungus, including . Shows potential as alternative treatment, but further research on active compounds and toxicity needed.

Aljuhani S et al (2024).
Front Microbiol.
PubMed:
38803379

Employing fruit juices to hydrolyze edible bird's nest and enhance the antioxidant, anti-tyrosinase, and wound-healing activities of the hydrolysates.

Nguyen TP et al (2024).
Heliyon.
PubMed:
38778992

Evaluation of five medicinal plants for the management of Sitophilus oryzae in stored rice and identification of insecticidal compound.

Mohammad MY et al (2024).
Heliyon.
PubMed:
38770290

Impact of water combined wet ball milling extraction and functional evaluation of dietary fiber from papaya (Carica papaya L).

Jiang G et al (2024).
Food Chem X.
PubMed:
38746781

Valorization applications of pineapple and papaya byproducts in food industry.

Review
Oliver-Simancas R et al (2024).
Compr Rev Food Sci Food Saf.
PubMed:
38720571

Knowledge and practices of traditional management of child malnutrition and associated pathologies in Benin.

Vissoh ACS et al (2024).
J Ethnobiol Ethnomed.
PubMed:
38693543

Evaluation of the effect of Carica papaya seed on the growth performance of fattening rabbits.

Konmy B et al (2024).
Trop Anim Health Prod.
PubMed:
38642256

Comparative proteomic analysis of papaya bud flowers reveals metabolic signatures and pathways driving hermaphrodite development.

Pereira Duarte R et al (2024).
Sci Rep.
PubMed:
38632280

Transcriptome, Plant Hormone, and Metabolome Analysis Reveals the Mechanism of Purple Pericarp Formation in 'Zihui' Papaya (Carica papaya L.).

Summary

'Zihui' papaya has purple pericarp due to upregulation of genes involved in anthocyanin synthesis. Understanding this mechanism can enhance fruit marketability and improve visual appeal.

Wu X et al (2024).
Molecules.
PubMed:
38611765

High-Value Compounds in Papaya By-Products (Carica papaya L. var. Formosa and Aliança): Potential Sustainable Use and Exploitation.

Vinha AF et al (2024).
Plants (Basel).
PubMed:
38611538

Antimicrobial and antibiofilm effect of cannabinoids from Cannabis sativa against methicillin-resistant Staphylococcus aureus (MRSA) causing bovine mastitis.

Summary

Researchers identified Cannabis sativa L. as a potent inhibitor of MRSA, with cannabidiol and Δ9-THC showing bactericidal action. This plant-based alternative may help combat antimicrobial resistance in bovine biofilm-associated MRSA infections.

Roshan M et al (2024).
Int Microbiol.
PubMed:
38568425

Anthelmintic screening of Bangladeshi medicinal plants and related phytochemicals using in vitro and in silico methods: An ethnobotanical perspective.

Summary

Researchers studied medicinal plants used by indigenous communities in Bangladesh for helminth infections. Discovering phytochemicals with anthelmintic activity could lead to new drugs to combat drug-resistant helminthiases in underdeveloped regions.

Khairuzzaman M et al (2024).
J Ethnopharmacol.
PubMed:
38565411

Safety of Oral Carica papaya L. Leaf 10% Ethanolic Extract for Acute and Chronic Toxicity Tests in Sprague Dawley Rats.

Taychaworaditsakul W et al (2024).
Toxics.
PubMed:
38535931

An Insight into Viscosity and Conductivity in the Formulation of Co-axial Electrospun Carica papaya Leaf Extract.

Tan SM et al (2024).
Drug Dev Ind Pharm.
PubMed:
38530403

SAR, Molecular Docking and Molecular Dynamic Simulation of Natural Inhibitors against SARS-CoV-2 Mpro Spike Protein.

Summary

Plant compound kaempferol was found to have strong binding affinity with SARS-CoV-2 main protease, suggesting potential for new COVID-19 treatment. This research could lead to the development of effective antiviral drugs.

Salamat A et al (2024).
Molecules.
PubMed:
38474656

Identification and Validation of Key Genes Related to Preferred Flavour Profiles in Australian Commercial Papaya (Carica papaya L.).

Zhou Z et al (2024).
Int J Mol Sci.
PubMed:
38474290

Draft genome sequence of Staphylococcus auricularis PAPLE_T1 isolate of Carica papaya revealing biosynthetic clusters for beneficial metabolites.

Adefiranye OO et al (2024).
Microbiol Resour Announc.
PubMed:
38456700

Effect of cinnamon essential oil/ γ-cyclodextrin inclusion complex on papaya quality and shelf-life.

Phan C et al (2024).
J Sci Food Agric.
PubMed:
38445761

Dataset on acido-biocatalysis of agro solid wastes in acidic medium for the conversion of pink solo Carica papaya seed oil to biodiesel fuel.

Nyorere O et al (2024).
Data Brief.
PubMed:
38439991

G-site residue S67 is involved in the fungicide-degrading activity of a tau class glutathione S-transferase from Carica papaya.

Wang SY et al (2024).
J Biol Chem.
PubMed:
38417796

Effects of Carica papaya peel meal-based diets on rabbit bucks' spermiogram and reaction time.

Shettima I et al (2024).
Trop Anim Health Prod.
PubMed:
38386155

TcSERPIN, an inhibitor that interacts with cocoa defense proteins and has biotechnological potential against human pathogens.

Ferreira MM et al (2024).
Front Plant Sci.
PubMed:
38348273

Evaluation of microbiome and physico-chemical profiles of fresh fruits of Musa paradisiaca, Citrus sinensis and Carica papaya at different ripening stages: Implication to quality and safety management.

Kifle DR et al (2024).
PLoS One.
PubMed:
38289915

Comprehensive investigation of BZR gene family in four dicots and the function of PtBZR9 and PtBZR12 under drought stress.

Wang L et al (2024).
Plant Physiol Biochem.
PubMed:
38266559

The Role of Plant Latex in Virus Biology.

Review
Merchán-Gaitán JB et al (2023).
Viruses.
PubMed:
38257746

Integrative Analysis of Oleosin Genes Provides Insights into Lineage-Specific Family Evolution in Brassicales.

Zou Z, Zhang L and Zhao Y (2024).
Plants (Basel).
PubMed:
38256833

First report of Ageratum yellow vein virus infecting papaya in Lampung, Indonesia.

Helina S et al (2024).
Mol Biol Rep.
PubMed:
38227086

Ethnobotanical study on medicinal plants in Melit area (North Darfur), Western Sudan.

Summary

This study aims to document the medicinal plants used in traditional medicine in the Melit area of North Darfur State, Sudan. This information is important for understanding and preserving ethnobotanical knowledge in this region.

Muhakr MAYM et al (2024).
J Ethnobiol Ethnomed.
PubMed:
38172804

Evaluation of supplemented protein-L-isoaspartate-O-methyltransferase (PIMT) gene of Carica papaya and Ricinus communis in stress survival of Escherichia coli BL21(DE3) cells.

Gupta A et al (2024).
Prep Biochem Biotechnol.
PubMed:
38170207

Genome-Wide Identification and Expression Pattern Profiling of the Aquaporin Gene Family in Papaya (Carica papaya L.).

Zeng Q et al (2023).
Int J Mol Sci.
PubMed:
38139107

First report of anthracnose fruit rot of papaya caused by Colletotrichum gigasporum in China.

He Y et al (2023).
Plant Dis.
PubMed:
38127631

Complete genome sequencing and construction of full-length infectious cDNA clone of papaya ringspot virus-HYD isolate and its efficient in planta expression.

Gupta P et al (2023).
Front Microbiol.
PubMed:
38107852

Medicinal plants used for management of diabetes and hypertension in Ghana.

Summary

This study investigated medicinal plants used by herbalists in Ghana for managing diabetes and hypertension. 39 species of plants were identified, 18 for hypertension, 12 for diabetes, and 9 for both. Some of these plants have potential therapeutic benefits, but clinical studies are needed for confirmation.

Asafo-Agyei T et al (2023).
Heliyon.
PubMed:
38076168

Unveiling the Potent Fibrino(geno)lytic, Anticoagulant, and Antithrombotic Effects of Papain, a Cysteine Protease from Carica papaya Latex Using κ-Carrageenan Rat Tail Thrombosis Model.

Yang HR et al (2023).
Int J Mol Sci.
PubMed:
38069092

Fabrication, organoleptic evaluation and in vitro characterization of cream loaded with Carica papaya seed extract.

Sarfraz M et al (2023).
J Cosmet Dermatol.
PubMed:
38050657

Time-Dependent Proteomic Signatures Associated with Embryogenic Callus Induction in Carica papaya L.

Xavier LR et al (2023).
Plants (Basel).
PubMed:
38005788

Analysis of Carica papaya Informs Lineage-Specific Evolution of the Aquaporin (AQP) Family in Brassicales.

Zou Z, Zheng Y and Xie Z (2023).
Plants (Basel).
PubMed:
38005748

The synthesis of papaya fruit flavor-related linalool was regulated by CpTPS18 and CpNAC56.

Yao Y et al (2023).
Plant Reprod.
PubMed:
37966580

Antioxidant activity of Carica papaya & Persea americana fruits against cadmium induced neurotoxicity, nephrotoxicity, and hepatotoxicity in rats with a computational approach.

Summary

Researchers investigated the harmful effects of cadmium on cells, including liver damage, neurotoxicity, and cancer. Current treatments have side effects, so finding safe ways to remove cadmium from the body is crucial.

Anjum S et al (2023).
J Trace Elem Med Biol.
PubMed:
37944220

Human schistosomiasis in Nigeria: present status, diagnosis, chemotherapy, and herbal medicines.

Summary

Nigeria has the highest burden of schistosomiasis in the world. This review summarizes the distribution, prevalence, diagnosis, treatment, and preventive measures. Limited use of diagnostic tools and preventive chemotherapy contribute to the high endemicity in Nigeria. The country has potential for discovering biomarkers and novel plant-derived treatments.

Review Cancer
Saidu U et al (2023).
Parasitol Res.
PubMed:
37851179

Effect of papaya (Carica papaya) seed as phytogenic feed additives on egg performance, egg quality and blood serum biochemical constituents of layer hens.

Dissa M, Yesuf YK and Belete E (2023).
Vet Med Sci.
PubMed:
37846947

Unripe Carica papaya Fresh Fruit Extract Protects against Methylglyoxal-Mediated Aging in Human Dermal Skin Fibroblasts.

Wattanapitayakul SK et al (2023).
Prev Nutr Food Sci.
PubMed:
37842248

Rutin extraction from female Carica papaya Linn. using ultrasound and microwave-assisted extractive methods: Optimization and extraction efficiencies.

Chew SK et al (2023).
Heliyon.
PubMed:
37810831

Blood and carcass characteristics of grower rabbits fed diets containing pawpaw (Carica papaya L.) leaf protein concentrate.

Agbonghae OW and Nwokoro SO (2023).
Trop Anim Health Prod.
PubMed:
37776386

Growth performance and nutrient digestibility of growing rabbits fed diets containing pawpaw (Carica papaya L.) leaf protein concentrate.

Agbonghae OW and Nwokoro SO (2023).
Trop Anim Health Prod.
PubMed:
37768437

Genomic and Transcriptomic Insights into the Evolution and Divergence of MIKC-Type MADS-Box Genes in Carica papaya.

Dai Y et al (2023).
Int J Mol Sci.
PubMed:
37762345

Regulation of Embden-Meyerhof-Parnas (EMP) Pathway and Tricarboxylic Acid (TCA) Cycle Concerning Aberrant Chilling Injury Behavior in Postharvest Papaya (Carica papaya L.).

Huang L et al (2023).
Int J Mol Sci.
PubMed:
37762201

TiO(2) incorporated into a blend of biopolymeric matrices improves film properties and affects the postharvest conservation of papaya fruits under UV light.

de Menezes FLG et al (2023).
Food Chem.
PubMed:
37690129

Anti-Inflammatory and Anti-Oxidative Effects of Polysaccharides Extracted from Unripe Carica papaya L. Fruit.

Lin TY et al (2023).
Antioxidants (Basel).
PubMed:
37627501

Phytochemical Extract from Carica papaya Leaves and Punica granatum Seeds as Therapy Against Cognitive Impairment in a Murine Model.

Summary

Scientists identified potential compounds, carpaine and punicalagin, in Carica papaya leaves and Punica granatum, that may improve cognition. These compounds were tested on rats, which showed improved memory and reduced GFAP expression in the hippocampus. Promising candidates for treating MCI and MND. (44 words, 260 characters)

Gonzalez-Ruiz C et al (2023).
Mol Neurobiol.
PubMed:
37626269

Exploring genetic diversity in inbred papaya lines for fruit quality in advanced stage of improvement.

Santana JGS et al (2023).
Sci Rep.
PubMed:
37596489

Genome-Wide Analysis of WRKY and NAC Transcription Factors in Carica papaya L. and Their Possible Role in the Loss of Drought Tolerance by Recent Cultivars through the Domestication of Their Wild Ancestors.

Summary

The study analyzed two families of transcription factors involved in drought response and found that the wild genotype showed higher expression levels than the commercial genotype, suggesting their importance in drought tolerance. The results also suggest that commercial genotypes may have lost their ability to respond to drought.

Arroyo-Álvarez E et al (2023).
Plants (Basel).
PubMed:
37570929

Anticancer potential of Carica papaya Linn black seed extract against human colon cancer cell line: in vitro study.

Summary

Papaya seeds may have anti-cancer properties, potentially benefiting colorectal cancer and other types, warranting further research for therapeutic purposes.

Mahrous NS and Noseer EA (2023).
BMC Complement Med Ther.
PubMed:
37516866

Improvement in the Stability and Bioaccessibility of Carotenoid and Carotenoid Esters from a Papaya By-Product Using O/W Emulsions.

Lara-Abia S et al (2023).
Foods.
PubMed:
37509746

Hypolipidaemic effects of papaya (Carica papaya L.) juice on rats fed on a high fat and fructose diet.

Matsuane C et al (2023).
J Nutr Sci.
PubMed:
37457684

Ameliorative effect of ethanolic extract of Carica papaya leaves on hyper-cholesterolemic rats: The egg yolk induced model.

Ademuyiwa OH et al (2023).
Heliyon.
PubMed:
37441376

Trace Elemental and Heavy Metal Levels in Frequently Consumed Local Vegetables of Three Chronic Kidney Disease-Prevalent Villages.

Murthy GN and Yadav PBS (2023).
Biol Trace Elem Res.
PubMed:
37428412

Screening for potential novel probiotic Levilactobacillus brevis RAMULAB52 with antihyperglycemic property from fermented Carica papaya L.

Sreepathi N et al (2023).
Front Microbiol.
PubMed:
37408641

In-silico screening and identification of potential drug-like compounds for dengue-associated thrombocytopenia from Carica papaya leaf extracts.

Banjan B et al (2023).
J Biomol Struct Dyn.
PubMed:
37394810

Mercuric Chloride Induced Nephrotoxicity: Ameliorative Effect of Carica papaya Leaves Confirmed by Histopathology, Immunohistochemistry, and Gene Expression Studies.

Maria Francis Y et al (2023).
ACS Omega.
PubMed:
37360438

In Vitro and In Vivo Cysticidal Effects of Carica Papaya Cell Suspensions.

Guzmán C et al (2023).
Infect Immun.
PubMed:
37341599

Identification and characterization of the LDAP family revealed GhLDAP2_Dt enhances drought tolerance in cotton.

Zhao Y et al (2023).
Front Plant Sci.
PubMed:
37260939

A Comparative Analysis of Effectiveness of Recombinant Interleukin-11 Versus Papaya Leaf Extract for Treatment of Thrombocytopenia: A Review.

Summary

This review examines the use of recombinant interleukin-11 (rhIL-11) and papaya leaf extract (CPLE) for treating thrombocytopenia. rhIL-11 is an FDA-approved treatment with side effects and high cost, while CPLE is a potentially cost-effective alternative.

Review Immunology
Mishra KP et al (2023).
Indian J Clin Biochem.
PubMed:
37234180

Life Table Parameters of Tetranychus merganser Boudreaux (Acari: Tetranychidae) on Five Host Plants.

Segura-Martínez MTJ et al (2023).
Insects.
PubMed:
37233101

Potential Plant-Based New Antiplasmodial Agent Used in Papua Island, Indonesia.

Review
Indradi RB et al (2023).
Plants (Basel).
PubMed:
37176870

Mechanism underlying Fanmugua () leaf multicomponent synergistic therapy for anemia: data mining based on hematopoietic network.

Lihong J et al (2023).
J Tradit Chin Med.
PubMed:
37147756

Potential therapeutic effect of Carica papaya leaves extract on immune response, biochemical and hematological mechanisms on cecal ligation and puncture model of sepsis in rats: an in vivo study.

Usmani J et al (2023).
3 Biotech.
PubMed:
37131965

Characterization of Green and Yellow Papaya (Carica papaya) for Anti-Diabetic Activity in Liver and Myoblast Cells and Wound-Healing Activity in Fibroblast Cells.

Li H et al (2023).
Nutrients.
PubMed:
37111148

Fusarium verticillioides Causing Root and Stem Rot in Papaya (Carica papaya) in Mexico.

Vega Gutiérrez TA et al (2023).
Plant Dis.
PubMed:
37079012

Spatial and Compositional Variations in Fruit Characteristics of Papaya (Carica papaya cv. Tainung No. 2) during Ripening.

Chung SW et al (2023).
Plants (Basel).
PubMed:
37050092

Uses of Papaya Leaf and Seaweed Supplementations for Controlling Glucose Homeostasis in Diabetes.

Review Diabetes
Nyakundi BB and Yang J (2023).
Int J Mol Sci.
PubMed:
37047820

Effect of chitosan with different molecular weights on the antifungal activity against Colletotrichum gloeosporioides and activation of the non-enzymatic antioxidant system on infected papaya.

López-Zazueta BA et al (2023).
J Food Sci.
PubMed:
37042208

Waste to value transformation: Converting Carica papaya seeds into green fluorescent carbon dots for simultaneous selective detection and degradation of tetracycline hydrochloride in water.

Laddha H et al (2023).
Environ Res.
PubMed:
37003557

Discovery of Potential Phytochemicals from Carica papaya Targeting BRCA-1 in Breast Cancer Treatment.

Ibrahim A et al (2023).
Appl Biochem Biotechnol.
PubMed:
36988843

Hypoglycemic Potential of Carica papaya in Liver Is Mediated through IRS-2/PI3K/SREBP-1c/GLUT2 Signaling in High-Fat-Diet-Induced Type-2 Diabetic Male Rats.

Roy JR et al (2023).
Toxics.
PubMed:
36977005

Evaluation of imazalil dissipation/migration in postharvest papaya using low-temperature partition extraction and GC-MS analysis.

de Freitas JF et al (2023).
Food Chem.
PubMed:
36963133

Antiviral and ROS scavenging potential of Carica papaya Linn and Psidium guajava leaves extract against HIV-1 infection.

Jadaun P et al (2023).
BMC Complement Med Ther.
PubMed:
36934258

Biopesticide efficacy of four plant essential oils against papaya mealybug, Paracoccus marginatus Williams and Granara de Willink (Hemiptera: Pseudococcidae).

Mwanauta RW, Ndakidemi PA and Venkataramana PB (2023).
Heliyon.
PubMed:
36923866

Plant Growth, Yield, and Fruit Size Improvements in 'Alicia' Papaya Multiplied by Grafting.

Salinas I et al (2023).
Plants (Basel).
PubMed:
36904050

Alteration of surface morphologies and chemical composition of cuticle in response to chilling injury in papaya (Carica papaya L.) after harvest.

Huang H and Wang L (2023).
Food Chem.
PubMed:
36870151

Cytotoxic Activity of the Ethyl Acetate Extract of Iraqi Carica papaya Leaves in Breast and Lung Cancer Cell Lines.

Basim S and Kasim AA (2023).
Asian Pac J Cancer Prev.
PubMed:
36853308

A Capsid Protein Fragment of a Fusagra-like Virus Found in Carica papaya Latex Interacts with the 50S Ribosomal Protein L17.

Maurastoni M et al (2023).
Viruses.
PubMed:
36851755

Carica Papaya Reduces High Fat Diet and Streptozotocin-Induced Development of Inflammation in Adipocyte via IL-1β/IL-6/TNF-α Mediated Signaling Mechanisms in Type-2 Diabetic Rats.

Rebecca Roy J et al (2023).
Curr Issues Mol Biol.
PubMed:
36826001

Validation of a Real-Time PCR Assay for Identification of Fresh and Processed Carica papaya Botanical Material: Using Synthetic DNA to Supplement Specificity Evaluation.

Patel R et al (2023).
Foods.
PubMed:
36766059

Molecular Docking of Bacterial Protein Modulators and Pharmacotherapeutics of Carica papaya Leaves as a Promising Therapy for Sepsis: Synchronising In Silico and In Vitro Studies.

Usmani J et al (2023).
Molecules.
PubMed:
36677632

Pollution impact assessment of secondary iron smelting on soil and some medicinal herbs grown at Fasina community in Ile-Ife, Nigeria.

Akinlade GO et al (2023).
Environ Monit Assess.
PubMed:
36640219

Comparative transcriptomics and genomic analyses reveal differential gene expression related to Colletotrichum brevisporum resistance in papaya (Carica papaya L.).

Yang M et al (2022).
Front Plant Sci.
PubMed:
36618670

Effect of carpaine, a major alkaloid from Carica papaya leaves, on dengue virus-2 infection and replication-an in-vitro and in-silico study.

Alagarasu K et al (2023).
Phytother Res.
PubMed:
36587936

Papaya 'sticky' disease caused by virus 'couples': a challenge for disease detection and management.

Quito-Avila D et al (2022).
Plant Dis.
PubMed:
36572970

Experimental Studies on Thermal-Barrier-Coated Engine Fuelled by a Blend of Eucalyptus Oil And DEE.

Venkatesan EP et al (2022).
ACS Omega.
PubMed:
36570292

Dietary higenamine from Annonaceae family fruits as a possible source of unintentional doping.

Muniz-Santos R et al (2023).
Forensic Sci Int.
PubMed:
36529085

Isolation and characterization of carpaine and dihydroxy derivative of carpaine from leaves of Carica papaya: Development of fast HPLC method and standardization of formulations.

Summary

This study isolated and identified carpaine, a major alkaloid, from dried Carica papaya leaves. A fast HPLC method was developed to quantify carpaine in leaf extract and marketed formulations.

Jadhav K et al (2022).
J Chromatogr B Analyt Technol Biomed Life Sci.
PubMed:
36442395

Prophylactic and curative effects of Carica papaya Linn. pulp extract against carbon tetrachloride-induced hepatotoxicity in male rats.

Shaban NZ et al (2023).
Environ Sci Pollut Res Int.
PubMed:
36396758

Nephroprotective plant species used in traditional Mayan Medicine for renal-associated diseases.

Review
Castañeda R et al (2023).
J Ethnopharmacol.
PubMed:
36181985

Modification of the Helper Component Proteinase of Papaya Ringspot Virus Vietnam Isolate to Generate Attenuated Mutants for Disease Management by Cross Protection.

Tran TT et al (2023).
Phytopathology.
PubMed:
36129763

Carica papaya Leaf Juice for Dengue: A Scoping Review.

Review
Teh BP et al (2022).
Nutrients.
PubMed:
35458146

The Future of Carica papaya Leaf Extract as an Herbal Medicine Product.

Review
Hariono M et al (2021).
Molecules.
PubMed:
34834014

Therapeutic application of Carica papaya leaf extract in the management of human diseases.

Review
Singh SP et al (2020).
Daru.
PubMed:
32367410

Carica papaya extract in dengue: a systematic review and meta-analysis.

Meta-Analysis
Rajapakse S et al (2019).
BMC Complement Altern Med.
PubMed:
31601215

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