Carissa spinarum

Ethnobotanical Studies

Studies

From desert flora to cancer therapy: systematic exploration of multi-pathway mechanisms using network pharmacology and molecular modeling approaches.

Summary

Researchers investigated Saudi Arabian flora compounds in treating ovarian cancer, identifying key genes and pathways. Compounds like ascorbic acid and hispidulin showed promising interactions with AKT1 and VEGFA proteins, suggesting potential for future anti-cancer treatments.

Cancer
Alblihy A et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1345415
PubMed:
38666020

Phytonutritional and Sensorial Assessment of a Novel Functional Beverage Formulated from an Underutilized Fruit of Carissa spinarum L.

Mamoona T et al (2023).
ACS Omega.
DOI:
10.1021/acsomega.3c03386
PubMed:
37720775

The traditional use of wild edible plants in pastoral and agro-pastoral communities of Mieso District, eastern Ethiopia.

Tahir M et al (2023).
Trop Med Health.
DOI:
10.1186/s41182-023-00505-z
PubMed:
36814353

Antidepressant-Like Activity of Solvent Fractions of the Root Bark of Carissa spinarum Linn. (Apocynaceae) in Rodents Involves Multiple Signaling Pathways.

Summary

Scientists researched the use of root bark from Linn. plants in the treatment of depression based on claims in Ethiopian folkloric medicine. They found that crude extracts of the bark had an antidepressant-like effect in rodents. This research suggests that Linn. root bark may have potential as a natural treatment for depression.

Neuroscience
Ali HS and Engidawork E (2022).
J Exp Pharmacol.
DOI:
10.2147/JEP.S386015
PubMed:
36531440

Woody Species Composition, Plant Communities, and Environmental Determinants in Gennemar Dry Afromontane Forest, Southern Ethiopia.

Ahmed S, Lemessa D and Seyum A (2022).
Scientifica (Cairo).
DOI:
10.1155/2022/7970435
PubMed:
35784587

"Photovoltaic response of Carissa spinarum berry extract in dye-sensitized solar cell".

Ahmad PA and Mir FA (2022).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-022-21584-1
PubMed:
35750905

Strychnos Potatorum L. Seed Polysaccharide-Based Stimuli-Responsive Hydrogels and Their Silver Nanocomposites for the Controlled Release of Chemotherapeutics and Antimicrobial Applications.

Antimicrobial
Nagaraja K et al (2022).
ACS Omega.
DOI:
10.1021/acsomega.2c00131
PubMed:
35474817

Phytochemical Investigation and Determination of Antibacterial Activity of Solvent Leave Extracts of Carissa spinarum.

Phytochemistry
Ayalew Tiruneh T et al (2022).
Infect Drug Resist.
DOI:
10.2147/IDR.S352049
PubMed:
35281572

Acyl Quinic Acid Derivatives Screened Out from Carissa spinarum by SOD-Affinity Ultrafiltration LC-MS and Their Antioxidative and Hepatoprotective Activities.

Liu Y et al (2021).
Antioxidants (Basel).
DOI:
10.3390/antiox10081302
PubMed:
34439550

Medicinal Plants Used for the Treatment of Erectile Dysfunction in Ethiopia: A Systematic Review.

Asmerom D et al (2021).
Biomed Res Int.
DOI:
10.1155/2021/6656406
PubMed:
34212038

Micro and nanoemulsions of Carissa spinarum fruit polyphenols, enhances anthocyanin stability and anti-quorum sensing activity: Comparison of degradation kinetics.

Nazareth MS et al (2021).
Food Chem.
DOI:
10.1016/j.foodchem.2021.129876
PubMed:
33940472

Cytotoxicity, Acute, and Subacute Study of Hydroalcoholic Root Extract of Carissa spinarum L. on Wistar Rats.

Dossou-Yovo KM et al (2021).
J Med Food.
DOI:
10.1089/jmf.2020.0065
PubMed:
33180011

Bioactive compounds from Carissa spinarum.

Wangteeraprasert R et al (2012).
Phytother Res.
DOI:
10.1002/ptr.4607
PubMed:
22308099

Proteomic study of Carissa spinarum in response to combined heat and drought stress.

Zhang M et al (2010).
Proteomics.
DOI:
10.1002/pmic.200900637
PubMed:
20661954