Common Names: carob, St. John's bread
This study evaluated the effects of Ganoderma lucidum and Ceratonia siliqua on blood parameters and anthropometric measures in women with fibromyalgia. The results did not show any significant differences, suggesting these supplements may not be effective. Further studies are needed to confirm these findings.
Researchers studied how carob extract and silver nanoparticles loaded with carob extract interact with the drug donepezil-HCl in treating dementia. Important for understanding potential herb-drug interactions in dementia treatment.
This study sequenced the entire genome of L and made the data publicly available. It could be useful for your lab's research and inform future experiments.
Researchers investigated the effects of carob extract and simvastatin on rats fed a high-cholesterol diet. They found that the combination reduced weight gain, lowered cholesterol levels, increased adiponectin, decreased leptin, and improved liver health. Carob may have potential in treating dyslipidemia and obesity.
Carob, a Mediterranean tree pod, is rich in fiber, vitamins, and minerals. It has potential health benefits including anti-diabetic and anti-inflammatory properties. This study explores carob extract's effect on gut health and glucose metabolism, potentially leading to new functional foods for managing chronic illnesses.
Scientists prepared and analyzed extracts from locust bean pulp and gum, identifying 76 phenolic compounds. The extracts showed antimicrobial activity and strong antioxidant properties, making them potential natural alternatives for medicinal industry additives.
Study: The carob tree has various medicinal properties and is used in traditional medicine. It contains compounds with antihypertensive, antidepressant, anti-obesity, and antihyperglycemic activities. This review explores the taxonomy, traditional uses, and biological properties of the carob tree (L.).
The Carob tree, also known as "L'Kharrûb" in Morocco, has been traditionally used for treating various ailments. To understand its properties, we analyzed the chemical composition of the ethanolic extract of carob leaves (CSEE) and conducted several tests. The CSEE extract, rich in phenolic acids and flavonoids, exhibited potent antioxidant activity, comparable to ascorbic acid. It also showed broad-spectrum antibacterial activity but moderate effectiveness against fungi. Additionally, the extract demonstrated dose-dependent inhibition of human breast cancer cell lines. At lower concentrations, it did not induce DNA damage, but a higher concentration showed genotoxic effects. Computational analysis predicted potential biological activities and evaluated the toxicity of the extract's constituents. This research provides valuable insights into the medicinal properties of the Carob tree.
Researchers investigated the effects of Ceratonia siliqua extract on Alzheimer's disease (AD) in mice. AD is caused by several factors including neuroinflammation, oxidative stress, and amyloid buildup. Mice injected with amyloid-β42, a protein involved in AD, were treated with the extract. The extract improved brain function and reduced AD symptoms, including inflammation and oxidative stress. Researchers found that the extract works by modulating specific pathways, which are involved in AD, in an α7-nAChR-dependent manner. The study suggests that Ceratonia siliqua could be a promising treatment for AD.
Carob seed peels (CSP) were orally administered to mice to evaluate their impact on the negative symptoms of schizophrenia. Behavioral tests were performed, and oxidative stress levels were evaluated by analyzing antioxidant enzyme levels. Both extracts showed remarkable antioxidant activity and proved to enhance cognitive impairment in animal models of schizophrenia while confirming the correlation between oxidative stress and psychiatric disorders. The study highlights the use of natural antioxidants in the improvement of cognitive impairment in schizophrenia.
Ethanol extracts of L. leaves can alleviate pain by blocking pain signals. The plant also has various other benefits like neuroprotection, lowering blood pressure, and reducing inflammation.
This study investigated the therapeutic effects of Carob pods on asthma and hypertension. The plant extract showed bronchorelaxant and vasorelaxant properties, and was safe to use without any adverse effects.