Chloranthus holostegius

Ethnobotanical Studies

Studies

Sesquiterpene dimers with a rare skeleton from Chloranthus holostegius exhibiting multidrug resistance reversal activity in vitro and in vivo.

Wang S et al (2024).
Fitoterapia.
DOI:
10.1016/j.fitote.2024.106125
PubMed:
39019239

Lindenane sesquiterpenoid dimers with NLRP3 inflammasome inhibitory activities from Chloranthus holostegius var. shimianensis.

Xiao L et al (2024).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2024.117087
PubMed:
38964178

Chlorahololide D, a Lindenane-Type Sesquiterpenoid Dimer from Chloranthus holostegius Suppressing Breast Cancer Progression.

Summary

Chlorahololide D, a compound found in plants, has potential as an anti-breast cancer drug. It blocks cell growth, triggers apoptosis, inhibits cell migration, and has anti-angiogenesis effects. More studies are needed to confirm its efficacy.

Cancer
Li Y et al (2023).
Molecules.
DOI:
10.3390/molecules28207070
PubMed:
37894550

Lindenane sesquiterpenoid dimers from Chloranthus holostegius with anti-neuroinflammatory activities in BV-2 microglia.

Summary

Scientists discovered fifteen previously unknown compounds, called chloranholides F-T, in the Chloranthus holostegius plant. These compounds show promising anti-inflammatory effects, inhibiting the production of the inflammatory mediator NO. Two specific compounds also suppressed the activity of iNOS and COX-2 enzymes.

Neuroscience
Zhan ZC et al (2023).
Phytochemistry.
DOI:
10.1016/j.phytochem.2023.113859
PubMed:
37709158

Chlotrichenes A and B, Two Lindenane Sesquiterpene Dimers with Highly Fused Carbon Skeletons from Chloranthus holostegius.

Chi J et al (2019).
Org Lett.
DOI:
10.1021/acs.orglett.8b04046
PubMed:
30652878

Chlorahololides A and B, two potent and selective blockers of the potassium channel isolated from Chloranthus holostegius.

Yang SP et al (2007).
Org Lett.
PubMed:
17263543

Phylogeny of Saururaceae based on mitochondrial matR gene sequence data.

Genetics
Meng SW et al (2002).
J Plant Res.
PubMed:
12884129