Chrysanthemum indicum

Ethnobotanical Studies

Studies

Buddleoside-rich Chrysanthemum indicum L. extract modulates macrophage-mediated inflammation to prevent metabolic syndrome induced by unhealthy diet.

Immunology
Zhou Y et al (2024).
BMC Complement Med Ther.
DOI:
10.1186/s12906-024-04583-2
PubMed:
39179999

Prevention of supercritical carbon dioxide fluid extract from Chrysanthemum indicum Linnén on cutaneous squamous cell carcinomas progression following UV irradiation in mice.

Luo QH et al (2024).
Exp Ther Med.
DOI:
10.3892/etm.2024.12619
PubMed:
38979021

Optimal harvest period and quality control markers of cultivated Flos Chrysanthemi Indici using untargeted/targeted metabolomics, chemometric analysis and in vivo study.

Yang P et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118533
PubMed:
38971347

Assessment of the Cu phytoremediation potential of Chrysanthemum indicum L. and Tagetes erecta L. using analysis of growth and physiological characteristics.

Nosratabadi S et al (2024).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-024-33941-3
PubMed:
38872040

The haplotype-resolved genome of diploid Chrysanthemum indicum unveils new acacetin synthases genes and their evolutionary history.

Genetics
Hou Z et al (2024).
Plant J.
DOI:
10.1111/tpj.16854
PubMed:
38864745

Comparative transcriptome analysis provides molecular insights into heterosis of waterlogging tolerance in Chrysanthemum indicum.

Summary

Study analyzed genetic mechanisms of heterosis for waterlogging tolerance in chrysanthemum using RNA-seq. Results could improve breeding methods for better plant resilience.

Review Genetics
Su J et al (2024).
BMC Plant Biol.
DOI:
10.1186/s12870-024-04954-4
PubMed:
38594635

Evaluation of Environmental Factor Effects on the Polyphenol and Flavonoid Content in the Leaves of Chrysanthemum indicum L. and Its Habitat Suitability Prediction Mapping.

Phytochemistry
Uranishi R et al (2024).
Molecules.
DOI:
10.3390/molecules29050927
PubMed:
38474439

Enhancing phosphate-solubilising microbial communities through artificial selection.

Faller L, Leite MFA and Kuramae EE (2024).
Nat Commun.
DOI:
10.1038/s41467-024-46060-x
PubMed:
38388537

Deep eutectic solvent combined with soybean as an efficient approach to enhance the content of apigenin in the Chrysanthemum indicum L. extract.

Thu Hang N et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2024.138793
PubMed:
38382256

Handelin alleviates cachexia- and aging-induced skeletal muscle atrophy by improving protein homeostasis and inhibiting inflammation.

Summary

Handelin, a compound from Chrysanthemum indicum, improves muscle health in aging worms. This study investigates its protective effects and mechanisms in a mouse muscle atrophy model induced by cachexia and aging.

Immunology
Zhang HJ et al (2023).
J Cachexia Sarcopenia Muscle.
DOI:
10.1002/jcsm.13381
PubMed:
38009816

Effect of E. cava and C. indicum Complex Extract on Phorbol 12-Myristate 13-Acetate (PMA)-Stimulated Inflammatory Response in Human Pulmonary Epithelial Cells and Particulate Matter (PM)(2.5)-Induced Pulmonary Inflammation in Mice.

Summary

The study found that the natural composite ED could reduce lung inflammation caused by fine particulate matter. It inhibited gene expression and reduced cellular accumulation and mucus secretion, indicating its potential as a therapeutic agent for respiratory diseases.

Immunology
Lee SG, Park CH and Kang H (2023).
Pharmaceutics.
DOI:
10.3390/pharmaceutics15112621
PubMed:
38004599

Two new quinolinone glycoalkaloids from Chrysanthemum indicum L. and their antimicrobial activity.

Summary

Researchers discovered two new compounds in L. plant through phytochemical investigation. Compound demonstrated significant antimicrobial effects against various pathogens, making it potentially valuable for developing new antimicrobial drugs.

Antimicrobial
Zhu Q et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2262719
PubMed:
37752790

Isocucurbic Acid Derivaties and Soluble Epoxide Hydroxylase Inhibitors from the Flowers of Chrysanthemum indicum L.

Thi Thu Trang B, Kim JH and Luyen BTT (2023).
Chem Biodivers.
DOI:
10.1002/cbdv.202301242
PubMed:
37690996

Identification of Efficacy-Associated Markers to Discriminate Flos Chrysanthemum and Flos Chrysanthemi Indici Based on Fingerprint-Activity Relationship Modeling: A Combined Evaluation over Chemical Consistence and Quality Consistence.

Liu F et al (2023).
Molecules.
DOI:
10.3390/molecules28176254
PubMed:
37687083

Comparative analysis of organellar genomes between diploid and tetraploid Chrysanthemum indicum with its relatives.

Summary

Study analyzed diploid and tetraploid plant plastomes and mitogenomes, identifying unique sequences in tetraploids and variations in mitogenome structure. Findings can aid in studying organellar genome evolution and have applications in conservation, breeding, and gene banking.

Genetics
Liu H et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1228551
PubMed:
37662149

ED Formula, a Complex of Ecklonia cava and Chrysanthemum indicum, Ameliorates Airway Inflammation in Lipopolysaccharide-Stimulated RAW Macrophages and Ovalbumin-Induced Asthma Mouse Model.

Summary

The study found that a formulation called ED, made from certain natural substances, has anti-inflammatory properties. It reduced inflammation in cells and in an asthma model, indicating its potential as a new treatment for inflammatory respiratory diseases.

AsthmaImmunology
Kang H et al (2023).
Pharmaceuticals (Basel).
DOI:
10.3390/ph16081185
PubMed:
37631100

Optimization of β-Cyclodextrin-Assisted Extraction of Apigenin and Luteolin from Chrysanthemum indicum L. Using Response Surface Methodology Combined with Different Optimization Algorithms and Evaluation of Its Antioxidant Capacity.

Immunology
Nguyen Thu H, Nguyen Thu H and Nguyen-Van P (2023).
Chem Biodivers.
DOI:
10.1002/cbdv.202300873
PubMed:
37440297

Germacrane-type sesquiterpenoids from the flowers of Chrysanthemum indicum with hepatoprotective activity.

Liu Y et al (2023).
Food Chem Toxicol.
DOI:
10.1016/j.fct.2023.113850
PubMed:
37225032

Evaluation of inducing activity of CIP elicitors from diverse sources based on monosaccharide composition and physiological indicators.

Luo G et al (2023).
J Plant Physiol.
DOI:
10.1016/j.jplph.2023.154002
PubMed:
37149979

Developing a UV-visible reporter-assisted CRISPR/Cas9 gene editing system to alter flowering time in Chrysanthemum indicum.

Genetics
Liu L et al (2023).
Plant Biotechnol J.
DOI:
10.1111/pbi.14062
PubMed:
37128708

Evaluation of Chrysanthemi Indici Flos germplasms based on nine bioactive constituents and color parameters.

Li J et al (2023).
PLoS One.
DOI:
10.1371/journal.pone.0283498
PubMed:
37083577

Systematic review on the anxiolytic and hypnotic effects of flower extracts in in vivo pre-clinical studies published from 2010 to 2020.

Summary

Researchers conducted a systematic review of scientific articles published between 2010 and 2020 that evaluated the anxiolytic, sedative, and/or hypnotic effects of flower extracts in pre-clinical animal models. They found that some flower extracts have an anxiolytic effect comparable to diazepam, but their therapeutic utility in anxiety disorders needs more investigation. The study compiled the characteristics of anxiety studies in animal models, evaluated locomotor activity, and the hypnotic effect of the extracts. The study revealed that matricaria chamomilla had a sedative effect, and 23 other flower plants had anxiolytic effects. However, more reliable behavioral tests and better experimental designs are needed to obtain more conclusive evidence with clinical significance.

Review Neuroscience
Meneses C et al (2023).
Phytother Res.
DOI:
10.1002/ptr.7830
PubMed:
37039741

Water Extract of Chrysanthemum indicum L. Flower Inhibits Capsaicin-Induced Systemic Low-Grade Inflammation by Modulating Gut Microbiota and Short-Chain Fatty Acids.

Immunology
Yang B et al (2023).
Nutrients.
DOI:
10.3390/nu15051069
PubMed:
36904069

Integrative metabolome and transcriptome analyses reveal the molecular mechanism underlying variation in floral scent during flower development of Chrysanthemum indicum var. aromaticum.

Genetics
Zhu L et al (2022).
Front Plant Sci.
DOI:
10.3389/fpls.2022.919151
PubMed:
36733600

Comparison of the Chemical Components, Efficacy and Mechanisms of Action of Chrysanthemum morifolium Flower and Its Wild Relative Chrysanthemum indicum Flower against Liver-Fire Hyperactivity Syndrome of Hypertension via Integrative Analyses.

Cardiology
Wang Y et al (2022).
Int J Mol Sci.
DOI:
10.3390/ijms232213767
PubMed:
36430265

Treatment effects of phosphorylated Chrysanthemum indicum polysaccharides on duck viral hepatitis by protecting mitochondrial function from oxidative damage.

Qiu T et al (2022).
Vet Microbiol.
DOI:
10.1016/j.vetmic.2022.109600
PubMed:
36395693

Genome-Wide Characterization of Chrysanthemum indicum Nuclear Factor Y, Subunit C Gene Family Reveals the Roles of CiNF-YCs in Flowering Regulation.

Genetics
Wang X et al (2022).
Int J Mol Sci.
DOI:
10.3390/ijms232112812
PubMed:
36361603

Linarin ameliorates dextran sulfate sodium-induced colitis in C57BL/6J mice via the improvement of intestinal barrier, suppression of inflammatory responses and modulation of gut microbiota.

Immunology
Jin C et al (2022).
Food Funct.
DOI:
10.1039/d2fo02128e
PubMed:
36155608

Novel Integrated Tiered Cumulative Risk Assessment of Heavy Metals in Food Homologous Traditional Chinese Medicine Based on a Real-Life-Exposure Scenario.

Zuo TT et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.908986
PubMed:
35814235

Two new guaianolide-type sesquiterpenoids with NO inhibitory activity from Chrysanthemum indicum.

Xue JF et al (2023).
J Asian Nat Prod Res.
DOI:
10.1080/10286020.2022.2091991
PubMed:
35771726

Biochemical and Physiological Changes during Early Adventitious Root Formation in Chrysanthemum indicum Linné Cuttings.

Ghimire BK et al (2022).
Plants (Basel).
DOI:
10.3390/plants11111440
PubMed:
35684213

Cosmos white rot: First characterization, physiology, host range, disease resistance, and chemical control.

Jahan R et al (2022).
J Basic Microbiol.
DOI:
10.1002/jobm.202200098
PubMed:
35642304

Transgenic Chrysanthemum indicum overexpressing cin-miR396a exhibits altered plant development and reduced salt and drought tolerance.

Liu X et al (2021).
Plant Physiol Biochem.
DOI:
10.1016/j.plaphy.2021.09.035
PubMed:
34619595

Chrysanthemum indicum suppresses adipogenesis by inhibiting mitotic clonal expansion in 3T3-L1 preadipocytes.

Genetics
Kim WJ et al (2021).
J Food Biochem.
DOI:
10.1111/jfbc.13896
PubMed:
34368979

Chrysanthemum indicum and Chrysanthemum morifolium: Chemical Composition of Their Essential Oils and Their Potential Use as Natural Preservatives with Antimicrobial and Antioxidant Activities.

AntimicrobialPhytochemistry
Youssef FS et al (2020).
Foods.
DOI:
10.3390/foods9101460
PubMed:
33066507

Molecular and morphological discrimination of Chrysanthemum indicum using allele-specific PCR and T-shaped trichome.

Genetics
Abid S et al (2020).
Mol Biol Rep.
DOI:
10.1007/s11033-020-05844-2
PubMed:
32974840