Cicer microphyllum

Ethnobotanical Studies

Gyirong Valley, Tibet, China

Uses: Food: fruit, raw

DOI:: 10.1186/s13002-022-00565-1
PubMed:: 36401315

Ladakh, Trans-Himalayan Region, India

Uses: Exhilarate and purify the blood.

DOI:: 10.3390/biology10090827
PubMed:: 34571704

Studies

Cryoconservation of in vitro grown shoot tips of Cicer microphyllum: A crop wild relative of chickpea.

Chander S et al (2023).; Cryo Letters.
PubMed:: 38311930

Promastigotes of Leishmania donovani exhibited sensitivity towards the high altitudinal plant Cicer microphyllu m.

Keshav P, Goyal DK and Kaur S (2021).; Curr Res Parasitol Vector Borne Dis.
DOI:: 10.1016/j.crpvbd.2021.100040
PubMed:: 35284854

Characterization of Seed Proteome Profile of Wild and Cultivated Chickpeas of India.

Dhar S et al (2021).; Protein Pept Lett.
DOI:: 10.2174/0929866527666200910164118
PubMed:: 32914710

Estrogen Receptor β Mediated Neuroprotective Efficacy of Cicer microphyllum Seed Extract in Global Hypoxia.

Summary

Researchers investigated the potential of Cicer microphyllum seed extract (CSE) to reduce neurodegeneration and improve memory in rats exposed to chronic hypoxia (low oxygen levels). CSE reduced neurodegeneration and dendritic atrophy in CA1 neurons and improved memory in hypoxic rats. This was attributed to antioxidant activity, activation of estrogen receptor beta (ERβ), and phosphorylation of extracellular signal regulated kinase (ERK1/2), resulting in increased expression of PSD-95. CSE also promoted dendritic arborization and independent of brain derived neurotrophic factor (BDNF) mediated signalling mechanisms. The findings suggest the neuroprotective potential of CSE in hypoxia and provide evidence for involvement of estrogen receptor and pCREB-mediated nootropic effect of the extract. Toxicological studies show that CSE is safe for consumption.

Endocrinology Neuroscience

Sharma D et al (2017).; Neurochem Res.
DOI:: 10.1007/s11064-017-2395-5
PubMed:: 28861754

Transcriptome landscape of perennial wild Cicer microphyllum uncovers functionally relevant molecular tags regulating agronomic traits in chickpea.

Genetics

Srivastava R et al (2016).; Sci Rep.
DOI:: 10.1038/srep33616
PubMed:: 27680662

Isolation, cytotoxic evaluation, and simultaneous quantification of eight bioactive secondary metabolites from Cicer microphyllum by high-performance thin-layer chromatography.

Phytochemistry

Dar AA et al (2015).; J Sep Sci.
DOI:: 10.1002/jssc.201500861
PubMed:: 26412260

Construction of cold induced subtracted cDNA library from Cicer microphyllum and transcript characterization of identified novel wound induced gene.

Genetics

Singh RK et al (2013).; Protoplasma.
DOI:: 10.1007/s00709-012-0429-z
PubMed:: 22798049

Alcoholic extract of Cicer microphyllum augments Th1 immune response in normal and chronically stressed Swiss albino mice.

Kour K et al (2011).; J Pharm Pharmacol.
DOI:: 10.1111/j.2042-7158.2010.01195.x
PubMed:: 21235592

Metallothionein-like gene from Cicer microphyllum is regulated by multiple abiotic stresses.

Singh RK et al (2011).; Protoplasma.
DOI:: 10.1007/s00709-010-0249-y
PubMed:: 21161305