Cinnamomum verum

Common Names: cinnamon

Ethnobotanical Studies

Studies

Innovative treatments for obesity and NAFLD: A bibliometric study on antioxidants, herbs, phytochemicals, and natural compounds.

Summary

Scientists analyzed research trends on antioxidants, herbs, and natural compounds for obesity and NAFLD. China, Korea, and USA are main contributors. Key compounds include resveratrol, curcumin, and quercetin. Study provides valuable insights for future research on obesity and NAFLD treatments.

Review Obesity
Pezzino S et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e35498
PubMed:
39220898

γCyclodextrin-assisted Aqueous Extract of Cinnamon for Cancer and Stress Management.

Summary

Tossers used Cyclodextrin to extract potent bioactive compounds from Cinnamon for potential medical benefits. Relevant for lab research on herbal remedies.

Cancer
Shi Y et al (2024).
Curr Top Med Chem.
DOI:
10.2174/0115680266309291240808114508
PubMed:
39171474

Medicinal Plants Cultivated in Egypt with Antiviral Potential: A Systematic Review.

Summary

Researchers studied antiviral properties of medicinal plants in Egypt, showing potential for treating serious viral diseases. Important due to high mortality rates, lack of cures, and emergence of resistant strains.

Antimicrobial
Elkhouly AM et al (2024).
Altern Ther Health Med.
PubMed:
39110055

Synergistic Interaction of Certain Essential Oils and Their Active Compounds with Fluconazole against Azole-resistant Strains of Cryptococcus neoformans.

Khan MSA et al (2024).
Ann Afr Med.
DOI:
10.4103/aam.aam_197_23
PubMed:
39034564

Bioinspired chitosan based functionalization of biomedical implant surfaces for enhanced hemocompatibility, antioxidation and anticoagulation potential: an in silico and in vitro study.

Hassan S et al (2024).
RSC Adv.
DOI:
10.1039/d4ra00796d
PubMed:
38952927

Synergistic Antibacterial Properties of Silver Nanoparticles and Its Reducing Agent from Cinnamon Bark Extract.

Granja Alvear A et al (2024).
Bioengineering (Basel).
DOI:
10.3390/bioengineering11050517
PubMed:
38790383

Antidepressant-Like Effects of Cinnamomum verum on Open-Space Forced Swim-Induced Depression in Mice.

Summary

Researchers tested cinnamon's antidepressant effects on mice with induced depression. Cinnamon decreased immobility time in a forced swim test, showing potential as a natural antidepressant. Consider cinnamon for its anti-depressant qualities.

Neuroscience
Yusha'u Y, Aminu Hanafi A and Muhammad Adam U (2023).
Niger J Physiol Sci.
DOI:
10.54548/njps.v38i2.11
PubMed:
38696678

Cinnamaldehyde attenuates streptozocin-induced diabetic osteoporosis in a rat model by modulating netrin-1/DCC-UNC5B signal transduction.

Summary

Cinnamaldehyde (CMD) improves bone strength and structure in diabetic osteoporosis (DOP) rats by inhibiting osteoclast activity through netrin-1/DCC/UNC5B signaling pathway. Relevant for treating bone diseases in diabetic patients.

ArthritisDiabetes
Ji S et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1367806
PubMed:
38628640

Nuclear Magnetic Resonance Fingerprints and Mini DNA Markers for the Authentication of Cinnamon Species Ingredients Used in Food and Natural Health Products.

GeneticsPhytochemistry
Ragupathy S et al (2024).
Plants (Basel).
DOI:
10.3390/plants13060841
PubMed:
38592863

Enzyme-Based Antiviral Potential of Cinnamomum verum J. Presl. Essential Oil and Its Major Component (E)-Cinnamaldehyde.

Summary

Researchers found that J. Presl. bark essential oil, specifically ()-cinnamaldehyde, inhibits key enzymes involved in viral entry. This could be promising for developing antiviral treatments.

AntimicrobialPhytochemistry
Karadağ AE et al (2024).
ACS Omega.
DOI:
10.1021/acsomega.3c09595
PubMed:
38559956

A Systematic Review Evaluating Cinnamon's Effects on Glucose Utilizing a Ranking System to Assess Bias and Study Quality.

Bakhach H et al (2024).
J Med Food.
DOI:
10.1089/jmf.2023.0277
PubMed:
38466959

Regulation of overexpressed efflux pump encoding genes by cinnamon oil and trimethoprim to abolish carbapenem-resistant Acinetobacter baumannii clinical strains.

Genetics
Saleh NM et al (2024).
BMC Microbiol.
DOI:
10.1186/s12866-024-03194-8
PubMed:
38331716

Elimination of detached Listeria monocytogenes from the biofilm on stainless steel surfaces during milk and cheese processing using natural plant extracts.

El-Sawy YNA et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-52394-9
PubMed:
38280925

Ethnobotanical study on medicinal plant knowledge among three ethnic groups in peri-urban areas of south-central Ethiopia.

Ethnobotany
Tamene S et al (2023).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-023-00629-w
PubMed:
37996915

In vitro and in silico prediction of antibacterial interaction between essential oils via graph embedding approach.

Yabuuchi H et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-46377-5
PubMed:
37919469

In Vitro Antioxidant and In Vivo Antigenotoxic Features of a Series of 61 Essential Oils and Quantitative Composition-Activity Relationships Modeled through Machine Learning Algorithms.

Immunology
Mladenović M et al (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12101815
PubMed:
37891894

Synergistic combination of Cinnamomum verum and Syzygium aromaticum treatment for cutaneous leishmaniasis and investigation of their molecular mechanism of action.

Essid R et al (2023).
Int J Environ Health Res.
DOI:
10.1080/09603123.2023.2267470
PubMed:
37855230

Synergistic Antibiofilm Action of Cinnamomum verum and Brazilian Green Propolis Hydroethanolic Extracts against Multidrug-Resistant Strains of Acinetobacter baumannii and Pseudomonas aeruginosa and Their Biocompatibility on Human Keratinocytes.

Meccatti VM et al (2023).
Molecules.
DOI:
10.3390/molecules28196904
PubMed:
37836747

Contribution to the improvement of the nutritional and functional properties of bread by incorporating cinnamon powder (Cinnamomum verum).

Bouatenin KMJ et al (2023).
Food Sci Nutr.
DOI:
10.1002/fsn3.3564
PubMed:
37823129

Chloroplast genome, nuclear ITS regions, mitogenome regions, and Skmer analysis resolved the genetic relationship among Cinnamomum species in Sri Lanka.

Summary

This study genetically characterizes Cinnamomum species, including Ceylon Cinnamon, using chloroplast genomes, nuclear ITS regions, and mitochondrial genes. It identifies the chloroplast gene ycf1 as a barcode and an indel region in ycf1 that differentiates C. verum from India and Sri Lanka.

Genetics
Bandaranayake PCG et al (2023).
PLoS One.
DOI:
10.1371/journal.pone.0291763
PubMed:
37729154

Cheminformatics and systems pharmacology approaches to unveil the potential plant bioactives to combat COVID-19.

Summary

Scientists used systems pharmacology and cheminformatics to identify 13 bioactive compounds from plants that have potential to counteract COVID-19. These compounds target specific genes related to the virus and showed better efficacy than current drugs. This study supports the use of natural products in developing new treatments for the disease.

COVID-19
Muralitharan D, Varadharajan V and Venkidasamy B (2023).
J Mol Recognit.
DOI:
10.1002/jmr.3055
PubMed:
37658788

Use of elemental profiles determined by energy-dispersive X-ray fluorescence and multivariate analyses to detect adulteration in Ceylon cinnamon.

Ghidotti M et al (2023).
Anal Bioanal Chem.
DOI:
10.1007/s00216-023-04817-1
PubMed:
37587311

Anti-Candida and Anti-Leishmanial Activities of Encapsulated Cinnamomum verum Essential Oil in Chitosan Nanoparticles.

Summary

Researchers optimized a technique to encapsulate essential oils in chitosan nanoparticles. The nanoparticles showed strong antibacterial, antifungal, and antiparasitic activity, making them a potential treatment for skin infections.

Phytochemistry
Essid R et al (2023).
Molecules.
DOI:
10.3390/molecules28155681
PubMed:
37570651

Proximate composition and mineral content of spices increasingly employed in the Mediterranean diet.

Al Dhaheri AS et al (2023).
J Nutr Sci.
DOI:
10.1017/jns.2023.52
PubMed:
37528827

Antimicrobial Efficacy of Essential Oils and Their Combination Against Microorganisms Associated With Postradiation Therapy in Patients With Head and Neck Cancer: An In Vitro Study.

Summary

Cinnamon and Cajeput essential oils (EOs) showed good antimicrobial activity against common microorganisms in head and neck cancer patients post-radiotherapy, comparable to chlorhexidine.

AntimicrobialCancer
Shah MA et al (2023).
Cureus.
DOI:
10.7759/cureus.40768
PubMed:
37485104

Choice Modeling for the Commercial Cultivation of Underutilized Aromatic Plants for Producing Mosquito Repellents: Targeting Rural Sector Income Generation.

Munugoda KD et al (2023).
Econ Bot.
DOI:
10.1007/s12231-023-09573-y
PubMed:
37359047

Development of species-specific ISSR-derived SCAR marker for early discrimination between Cinnamomum verum and Cinnamomum cassia.

Gangwar H et al (2023).
Mol Biol Rep.
DOI:
10.1007/s11033-023-08578-z
PubMed:
37306873

Evaluation of the Effectiveness of an Herbal Formulation of Boswellia sacra Flueck. In Improving Cognitive and Behavioral Symptoms in Patients with Cognitive Impairment and Alzheimer's Disease.

Summary

Researchers investigated an herbal formula for improving symptoms in patients with mild cognitive impairment (MCI) and mild-to-moderate Alzheimer's disease (AD). The study aimed to evaluate the effectiveness of the formula on cognitive and behavioral symptoms. The findings might suggest future treatment options for MCI and AD patients.

Neuroscience
Panahishokouh M et al (2023).
J Res Pharm Pract.
DOI:
10.4103/jrpp.jrpp_73_22
PubMed:
37304222

Digested Cinnamon (Cinnamomum verum J. Presl) Bark Extract Modulates Claudin-2 Gene Expression and Protein Levels under TNFα/IL-1β Inflammatory Stimulus.

GeneticsImmunology
Lonati E et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24119201
PubMed:
37298151

Validation of γ-radiation and their effect on phenolic compounds, antioxidant activity, and microbial load of fennel (Foeniculum vulgare) seeds and cinnamon (Cinnamomum verum) sticks.

ImmunologyPhytochemistry
Ahmed SM and Hassan AB (2023).
Food Sci Nutr.
DOI:
10.1002/fsn3.3233
PubMed:
37051350

Bioactive Compositions of Cinnamon (Cinnamomum verum J. Presl) Extracts and Their Capacities in Suppressing SARS-CoV-2 Spike Protein Binding to ACE2, Inhibiting ACE2, and Scavenging Free Radicals.

Summary

Cinnamon extracts contain bioactive compounds that can inhibit the activity of the virus and increase antioxidant activity, potentially reducing the risk of COVID-19 infection. Ethanol extract showed higher phenolic content and greater free radical scavenging activity compared to water extract, indicating cinnamon's preventive properties against SARS-CoV-2.

COVID-19
Xie Z et al (2023).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.3c00285
PubMed:
36940448

Analyzing cross-talk of EPO and EGF genes along with evaluating therapeutic potential of Cinnamomum verum in cigarette-smoke-induced lung pathophysiology in rat model.

Genetics
Anwar H et al (2023).
Food Sci Nutr.
DOI:
10.1002/fsn3.3188
PubMed:
36911850

Combined antidiabetic potential of camel milk yogurt with Cinnamomum verum and Stevia rebaudiana by using rodent modelling.

Diabetes
Hameed A et al (2023).
J Food Sci Technol.
DOI:
10.1007/s13197-023-05671-w
PubMed:
36908342

Antioxidant and Anti-Inflammatory Effect of Cinnamon (Cinnamomum verum J. Presl) Bark Extract after In Vitro Digestion Simulation.

Immunology
Pagliari S et al (2023).
Foods.
DOI:
10.3390/foods12030452
PubMed:
36765979

Cinnamomum verum extract inhibits NOX2/ROS and PKCδ/JNK/AP-1/NF-κB pathway-mediated inflammatory response in PMA-stimulated THP-1 monocytes.

Immunology
Kim NY et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.154685
PubMed:
36753827

Ovicidal toxicity of plant essential oils and their major constituents against two mosquito vectors and their non-target aquatic predators.

Phytochemistry
Moungthipmalai T et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-29421-2
PubMed:
36746998

Macroscopic and microscopic study on floral biology and pollination of Cinnamomum verum Blume (Sri Lankan).

Hathurusinghe BM, Pushpakumara DKNG and Bandaranayake PCG (2023).
PLoS One.
DOI:
10.1371/journal.pone.0271938
PubMed:
36730137

Assessment of angiotensin converting enzyme inhibitory activity and quality attributes of yoghurt enriched with Cinnamomum verum, Elettaria cardamomum, Beta vulgaris and Brassica oleracea.

Abdullah R et al (2023).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2023.103556
PubMed:
36698857

Synthesis and characterization of activated carbon supported bimetallic Pd based nanoparticles and their sensor and antibacterial investigation.

Ameen F et al (2023).
Environ Res.
DOI:
10.1016/j.envres.2023.115287
PubMed:
36640937

Rapid and non-destructive cinnamon authentication by NIR-hyperspectral imaging and classification chemometrics tools.

Cruz-Tirado JP et al (2023).
Spectrochim Acta A Mol Biomol Spectrosc.
DOI:
10.1016/j.saa.2022.122226
PubMed:
36512964

Zingiber officinale, Phyllanthus emblica, Cinnamomum verum, and Curcuma longa to Prevent Type 2 Diabetes: an Integrative Review.

Diabetes
Subodhini Wijewardhana U et al (2022).
Curr Diabetes Rev.
DOI:
10.2174/1573399819666221124104401
PubMed:
36424773

Cinnamomum verum J. Presl. Bark essential oil: in vitro investigation of anti-cholinesterase, anti-BACE1, and neuroprotective activity.

Summary

Six plant essential oils commonly used in Iranian Traditional Medicine for memory improvement were tested for their ability to inhibit cholinesterase, an enzyme whose inhibition is a key target in the treatment of Alzheimer's disease. The plants tested were cinnamon, myrtle, rue, dill, nutmeg, and saffron. These findings may support the continued use of these natural remedies for memory improvement and suggest the potential of using these plants for developing drugs to treat AD.

NeurosciencePhytochemistry
Saeedi M et al (2022).
BMC Complement Med Ther.
DOI:
10.1186/s12906-022-03767-y
PubMed:
36401242

Safety and efficacy of feed additives consisting of essential oils from the bark and the leaves of Cinnamomum verum J. Presl (cinnamon bark oil and cinnamon leaf oil) for use in all animal species (FEFANA asbl).

Phytochemistry
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) et al (2022).
EFSA J.
DOI:
10.2903/j.efsa.2022.7601
PubMed:
36304835

Cinnamomum verum J. Presl Bark Contains High Contents of Nicotinamide Mononucleotide.

Yan J et al (2022).
Molecules.
DOI:
10.3390/molecules27207054
PubMed:
36296647

Microscopic visualization of the antibiofilm potential of essential oils against Staphylococcus aureus and Klebsiella pneumoniae.

Phytochemistry
Sarwar W, Ali Q and Ahmed S (2022).
Microsc Res Tech.
DOI:
10.1002/jemt.24243
PubMed:
36250506

Safety and efficacy of a feed additive consisting of a tincture from the bark of Cinnamomum verum J. Presl (cinnamon tincture) for use in all animal species (FEFANA asbl).

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) et al (2021).
EFSA J.
DOI:
10.2903/j.efsa.2021.6986
PubMed:
34934461

Analysis of the effectiveness of cinnamon (Cinnamomum verum) in the reduction of glycemic and lipidic levels of adults with type 2 diabetes: A study protocol.

Diabetes
Neto JCGL et al (2020).
Medicine (Baltimore).
DOI:
10.1097/MD.0000000000018553
PubMed:
31895796

Herbal Medicine for Oligomenorrhea and Amenorrhea: A Systematic Review of Ancient and Conventional Medicine.

Review
Moini Jazani A et al (2018).
Biomed Res Int.
DOI:
10.1155/2018/3052768
PubMed:
29744355

Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial.

EndocrinologyObesity
Arentz S et al (2017).
Phytother Res.
DOI:
10.1002/ptr.5858
PubMed:
28685911