Cinnamomum zeylanicum

Ethnobotanical Studies

Clinical Trials

Effect of cinnamon spice on continuously monitored glycemic response in adults with prediabetes: a 4-week randomized controlled crossover trial.

Researchers conducted a meta-analysis on cinnamon's effects on blood glucose levels, finding inconclusive results. More research is needed to determine potential health benefits.

Zelicha H et al (2024).
Am J Clin Nutr.
PubMed:
38290699

Effectiveness of a Food Supplement Based on Glucomannan, D-Chiro-Inositol, Cinnamomum zeylanicum Blume and Inulin in Patients with Metabolic Syndrome.

Citarrella R et al (2024).
Nutrients.
PubMed:
38257142

Effectiveness of cinnamon in the reduction of lipid levels in people with diabetes: a randomized clinical trial.

Researchers studied the impact of cinnamon on lipid levels in individuals with diabetes. Care about the findings if you want to explore natural ways to manage lipid levels in diabetes.

Lira Neto JCG et al (2023).
Rev Gaucha Enferm.
PubMed:
37909519

Cinnamon (Cinnamomum cassia) water extract improves diarrhea symptoms by changing the gut environment: a randomized controlled trial.

Cinnamon water extract (CWE) improved diarrhea symptoms, increased colonic transit time, and altered gut microbiota composition by increasing certain metabolites and changing microbial groups.

Park SY et al (2023).
Food Funct.
PubMed:
36655542

Cinnamomum zeylanicum (Ceylon cinnamon) as a potential pharmaceutical agent for type-2 diabetes mellitus: study protocol for a randomized controlled trial.

This study investigates the potential anti-diabetic effects of Sri Lankan cinnamon extract in patients with type-2 diabetes, which has not been explored before.

Ranasinghe P et al (2017).
Trials.
PubMed:
28962661

Studies

Cinnamon extracts, trans-cinnamaldehyde and trans-cinnamic acid inhibit HDAC 1 activity.

Koyu H et al (2024).
Food Funct.
PubMed:
39145543

Enhanced repellent and anti-nutritional activities of polymeric nanoparticles containing essential oils against red flour beetle, Tribolium castaneum.

Khandehroo F et al (2024).
Sci Rep.
PubMed:
39127742

Electron beam irradiation developed cinnamon oil- (polyvinyl alcohol/gum tragacanth)/graphene oxide dressing hydrogels: Antimicrobial and healing assessments.

Summary

Researchers developed wound dressings using TG, PVA, GO, and CMO with electron beam irradiation. Improved gel content, antimicrobial activity, and wound healing efficacy. CMO-(PVA/TG)-GO dressings show promise for wound care.

Elshahawy MF et al (2024).
Int J Biol Macromol.
PubMed:
39098683

Improving the performance of kraft paper by cinnamon essential oil/soybean protein isolate microcapsules and konjac glucomannan for citrus preservation.

Liu Y et al (2024).
Int J Biol Macromol.
PubMed:
39094880

Pectin-based cinnamon essential oil Pickering emulsion film with two-sided differential wettability: A major role in the spatial distribution of microdroplets.

Yu Y et al (2024).
Int J Biol Macromol.
PubMed:
39084975

Effect of cinnamon as a Chinese herbal medicine on markers of cardiovascular risk in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials.

Summary

Study found that cinnamon supplementation can improve cardiovascular risk markers in women with PCOS. Cinnamon's anti-inflammatory and insulin-sensitizing properties make it a potential therapeutic agent for PCOS-related cardiovascular complications.

Xiaomei Z and Xiaoyan F (2024).
Eur J Obstet Gynecol Reprod Biol.
PubMed:
39053085

Investigation of the Antitrichomonal Activity of Cinnamaldehyde, Carvacrol and Thymol and Synergy with Metronidazole.

Özel Y et al (2024).
Turkiye Parazitol Derg.
PubMed:
38958374

Physicochemical Characterization of Yogurt Fortified with Microencapsulated Cinnamon (Cinnamomum zeylanicum) and Its Effects on Metabolic Syndrome Induced in Rabbits (Oryctolagus cuniculus).

Riós Pérez MF et al (2024).
J Med Food.
PubMed:
38910556

Characteristics of corn starch/polyvinyl alcohol composite film with improved flexibility and UV shielding ability by novel approach combining chemical cross-linking and physical blending.

Wei HN et al (2024).
Food Chem.
PubMed:
38901078

Single and combined application of bacteriophage and cinnamon oils against pathogenic Listeria monocytogenes in milk and smoked salmon.

Maung AT et al (2024).
Int J Food Microbiol.
PubMed:
38878706

Microbial load reduction in stored raw beef meat using chitosan/starch-based active packaging films incorporated with cellulose nanofibers and cinnamon essential oil.

K S et al (2024).
Meat Sci.
PubMed:
38878411

Enhancing Therapeutic Efficacy of Cinnamon Essential Oil by Nanoemulsification for Intravaginal Treatment of Candida Vaginitis.

Lin YT et al (2024).
Int J Nanomedicine.
PubMed:
38828194

Properties and application of antioxidant and antibacterial composite films based on methylcellulose and spine grape pomace fabricated by thermos-compression molding.

Dai M et al (2024).
Food Chem.
PubMed:
38788649

Biological fate, functional properties, and design strategies for oral delivery systems for cinnamaldehyde.

Review
Weng X, Ho CT and Lu M (2024).
Food Funct.
PubMed:
38767618

Potential fungicidal and antiaflatoxigenic effects of cinnamon essential oils on Aspergillus flavus inhabiting the stored wheat grains.

Gwad MMA et al (2024).
BMC Plant Biol.
PubMed:
38741071

Exploring non-cytotoxic, antioxidant, and anti-inflammatory properties of selenium nanoparticles synthesized from Gymnema sylvestre and Cinnamon cassia extracts for herbal nanomedicine.

Bi Bi S et al (2024).
Microb Pathog.
PubMed:
38734323

Exploring the mechanism of action of the combination of cinnamon and motherwort in the treatment of benign prostatic hyperplasia: A network pharmacology study.

Yang J et al (2024).
Medicine (Baltimore).
PubMed:
38669415

In Vitro and In Vivo Anti-Inflammatory Activity of a Combination of Extracts from Cinnamomum zeylanicum, Alpinia galanga, and Withania somnifera used in Unani Medicine.

Shiffa M et al (2024).
Altern Ther Health Med.
PubMed:
38581340

3D printed cinnamon essential oil/banana peel carbon dots loaded corn starch/gelatin bilayer film with enhanced functionality for food packaging application.

Chen K et al (2024).
Food Chem.
PubMed:
38574719

Antimicrobial activity of essential oils against biofilms formed in dental acrylic resin: a systematic review of in vitro studies.

Summary

Study evaluated essential oils for antimicrobial activity against biofilms on dental acrylic resin. EOs of and showed higher action than standard treatments. EOs could be effective in reducing biofilm on dental acrylic resin.

Carvalho-Silva JM et al (2024).
Biofouling.
PubMed:
38538551

An in vitro study elucidating the synergistic effects of aqueous cinnamon extract and an anti-TNF-α biotherapeutic: implications for a complementary and alternative therapy for non-responders.

Khedkar S and Khan MA (2024).
BMC Complement Med Ther.
PubMed:
38521924

CoSn(OH)(6) nanocubes as a solid sorbent for the effective preconcentration of copper ions in cinnamon (Cinnamomum zeylanicum) extract.

Bahçıvan A et al (2024).
Food Chem.
PubMed:
38513484

Enhancing fluconazole reactivation against Candida auris: efficacy of Cinnamomum zeylanicum essential oil versus cinnamaldehyde.

Di Vito M et al (2024).
Microbiol Spectr.
PubMed:
38483141

Using Essential Oils to Reduce Yersinia enterocolitica in Minced Meat and in Biofilms.

Vidaković Knežević S et al (2024).
Foods.
PubMed:
38472919

A Systematic Review Evaluating Cinnamon's Effects on Glucose Utilizing a Ranking System to Assess Bias and Study Quality.

Bakhach H et al (2024).
J Med Food.
PubMed:
38466959

Assessing the efficacy of cinnamon compounds against H. pylori through molecular docking, MD Simulations and ADMET analyses.

Sarwar MF et al (2024).
PLoS One.
PubMed:
38466698

Effect of cinnamon essential oil/ γ-cyclodextrin inclusion complex on papaya quality and shelf-life.

Phan C et al (2024).
J Sci Food Agric.
PubMed:
38445761

Zein and tannic acid hybrid particles improving physical stability, controlled release properties, and antimicrobial activity of cinnamon essential oil loaded Pickering emulsions.

Summary

Tannic acid and cinnamon essential oil loaded Pickering emulsion improves food preservation with enhanced stability and antimicrobial activity. Ideal for co-loading multiple agents for effective delivery system.

Fan S et al (2024).
Food Chem.
PubMed:
38428085

Evaluation of the efficacy of cinnamon oil on Aspergillus flavus and Fusarium proliferatum growth and mycotoxin production on paddy and polished rice: Towards a mitigation strategy.

Phan LTK et al (2024).
Int J Food Microbiol.
PubMed:
38422676

Effect of TEMPO-oxidized bacterial cellulose nanofibers stabilized Pickering emulsion of cinnamon essential oil on structure and properties of gelatin composite films.

Li D et al (2024).
Int J Biol Macromol.
PubMed:
38401581

Regulation of overexpressed efflux pump encoding genes by cinnamon oil and trimethoprim to abolish carbapenem-resistant Acinetobacter baumannii clinical strains.

Saleh NM et al (2024).
BMC Microbiol.
PubMed:
38331716

Elimination of detached Listeria monocytogenes from the biofilm on stainless steel surfaces during milk and cheese processing using natural plant extracts.

El-Sawy YNA et al (2024).
Sci Rep.
PubMed:
38280925

Application of HPLC-UV combined with chemometrics for the detection and quantification of 'true cinnamon' adulteration.

Pages-Rebull J et al (2024).
Talanta.
PubMed:
38266436

Screening of Multitarget Compounds against Acetaminophen Hepatic Toxicity Using In Silico, In Vitro, and In Vivo Approaches.

Ali M et al (2024).
Molecules.
PubMed:
38257341

Effect of pin-to-plate atmospheric cold plasma (ACP) on microbial load and physicochemical properties in cinnamon, black pepper, and fennel.

Kahar SP, Shelar A and Annapure US (2024).
Food Res Int.
PubMed:
38225121

Preparation of bioactive film based on chitosan and essential oils mixture for enhanced preservation of food products.

Mouhoub A et al (2024).
Int J Biol Macromol.
PubMed:
38219942

Effects of swimming training in hot and cold temperatures combined with cinnamon supplementation on HbA1C levels, TBC1D1, and TBC1D4 in diabetic rats.

Summary

Researchers studied the impact of cold water swimming exercise and cinnamon supplements on HbA1C levels and two genes in diabetic rats. This non-drug approach could help prevent and improve diabetes in developing countries.

Tayebi SM et al (2024).
Nutr Diabetes.
PubMed:
38195613

Preparation and characterization of starch/PBAT film containing hydroxypropyl-β-cyclodextrin/ethyl lauroyl arginate/cinnamon essential oil microcapsules and its application in the preservation of strawberry.

Hu D et al (2024).
Int J Biol Macromol.
PubMed:
38185302

Coated composite paper with nano-chitosan/cinnamon essential oil-nanoemulsion containing grafted CNC@ZnO nanohybrid; synthesis, characterization and inhibitory activity on Escherichia coli biofilm developed on grey zucchini.

Karami-Eshkaftaki Z et al (2024).
Int J Biol Macromol.
PubMed:
38158064

Enhanced mechanical properties and antibacterial activities of chitosan films through incorporating zein-gallic acid conjugate stabilized cinnamon essential oil Pickering emulsion.

Yang L et al (2024).
Int J Biol Macromol.
PubMed:
38143071

Effects of Cinnamon (Cinnamomum zeylanicum) Extract on Adipocyte Differentiation in 3T3-L1 Cells and Lipid Accumulation in Mice Fed a High-Fat Diet.

Oh J et al (2023).
Nutrients.
PubMed:
38140369

The Inhibition of Mitogen-Activated Protein Kinases (MAPKs) and NF-κB Underlies the Neuroprotective Capacity of a Cinnamon/Curcumin/Turmeric Spice Blend in Aβ-Exposed THP-1 Cells.

Summary

A spice blend of cinnamon bark and turmeric root extracts (CCSB) showed strong antioxidant properties and reduced inflammation in brain cells exposed to β-amyloid. It has potential as a treatment for Alzheimer's disease.

Maugeri A et al (2023).
Molecules.
PubMed:
38138438

Insecticidal plants as trade opportunities and use by small vegetable producers: an example using essential oils to control Diaphania hyalinata (Lepidoptera: Crambidae).

Silva IMD et al (2023).
An Acad Bras Cienc.
PubMed:
38126611

Determination of descriptors for the principal flavor compounds of the cinnamons of commerce by gas chromatography and liquid-liquid partition.

Ariyasena TC, Hewage KP and Poole CF (2024).
J Chromatogr A.
PubMed:
38113578

Systematic analysis of antimicrobial activity, phytochemistry, and in silico molecular interaction of selected essential oils and their formulations from different Indian spices against foodborne bacteria.

Summary

Indian spice essential oils such as cardamom, clove, cinnamon, and bay leaves exhibit antibacterial properties, with cinnamon and a cardamom-cinnamon blend being the most effective. Cinnamon oil's active compounds bind to bacterial proteins, increasing susceptibility to the oil, making these oils potential weapons against foodborne pathogens.

Gupta N et al (2023).
Heliyon.
PubMed:
38107328

Biodegradable PBAT/PLA blend films incorporated with turmeric and cinnamomum powder: A potential alternative for active food packaging.

de Castro LLRL et al (2024).
Food Chem.
PubMed:
38100869

Consequences of dietary cinnamon and ginger oils supplementation on blood biochemical parameters, oxidative status, and tissue histomorphology of growing Japanese quails.

Abd El-Hack ME et al (2024).
Poult Sci.
PubMed:
38096669

Cinnamomi cortex extract mitigated monosodium urate-induced acute gouty arthritis in rats through nuclear factor-κB-NOD-like receptor thermal protein domain associated protein 3 signaling pathway.

Zhang G et al (2024).
J Vet Med Sci.
PubMed:
38030283

Adjuvant Effect of Cinnamon Polyphenolic Components in Colorectal Cancer Cell Lines.

Summary

Cinnamon extracts, when co-administered with the anticancer drug cetuximab, reduce the required drug dose for colorectal cancer treatment. These extracts induce apoptosis in cancer cells and may be used as adjuvants to minimize side effects of the drug.

Palmioli A et al (2023).
Int J Mol Sci.
PubMed:
38003308

Synergistic bactericidal mechanisms of RF energy simultaneously combined with cinnamon essential oil or epsilon-polylysine against Salmonella revealed at cellular and metabolic levels.

Xu Y, Guan X and Wang S (2024).
Int J Food Microbiol.
PubMed:
37907022

Repellent effects of Chinese cinnamon oil on nymphal ticks of Haemaphysalis longicornis, Rhipicephalus haemaphysaloides, and Hyalomma asiaticum.

Zhou Y et al (2023).
Exp Appl Acarol.
PubMed:
37870735

Antifungal activity of volatile organic compounds from essential oils against the postharvest pathogens Botrytis cinerea, Monilinia fructicola, Monilinia fructigena, and Monilinia laxa.

Summary

Plant essential oils (EOs) were tested for their antifungal activity against gray mold and brown rot. Results showed that certain EOs inhibited the growth of the fungi, suggesting their potential use for controlling these diseases in fruit and vegetable storage.

Álvarez-García S, Moumni M and Romanazzi G (2023).
Front Plant Sci.
PubMed:
37860258

Synergistic combination of Cinnamomum verum and Syzygium aromaticum treatment for cutaneous leishmaniasis and investigation of their molecular mechanism of action.

Essid R et al (2023).
Int J Environ Health Res.
PubMed:
37855230

Synergistic Antibiofilm Action of Cinnamomum verum and Brazilian Green Propolis Hydroethanolic Extracts against Multidrug-Resistant Strains of Acinetobacter baumannii and Pseudomonas aeruginosa and Their Biocompatibility on Human Keratinocytes.

Meccatti VM et al (2023).
Molecules.
PubMed:
37836747

Combined antifungal effects of the vapor phases of Zataria multiflora and Cinnamomum zeylanicum essential oils against Aspergillus flavus and Penicillium citrinum in vitro and cheese.

Summary

This study found that the vapor phases of ZEO and CEO, containing thymol and cinnamaldehyde, had strong antifungal effects against fungi in vitro and in cheese. They could be used as natural antifungals in cheese production, replacing synthetic preservatives.

Imaz L, Aliakbarlu J and Lin L (2023).
Food Sci Nutr.
PubMed:
37823120

The effect of cinnamon supplementation on glycemic control in patients with type 2 diabetes mellitus: An updated systematic review and dose-response meta-analysis of randomized controlled trials.

Summary

This meta-analysis of 24 randomized controlled trials found that cinnamon supplementation significantly reduced fasting blood sugar, insulin resistance, and hemoglobin A1C levels in patients with type 2 diabetes. Cinnamon may be an effective adjunct therapy for managing diabetes.

Meta-Analysis Diabetes
Moridpour AH et al (2024).
Phytother Res.
PubMed:
37818728

Enrichment of cinnamaldehyde from Cinnamomum cassia by electroosmotic coupled particle-assisted solvent flotation.

Yan C et al (2023).
J Chromatogr A.
PubMed:
37778100

Evaluation of the antibacterial activity of cinnamon essential oil and its individual compounds on Aggregatibacter actinomycetemcomitans isolated from black extrinsic tooth stain: an in vitro study.

Lotfy WA, Matar MA and Alkersh BM (2023).
Eur Arch Paediatr Dent.
PubMed:
37747658

Chloroplast genome, nuclear ITS regions, mitogenome regions, and Skmer analysis resolved the genetic relationship among Cinnamomum species in Sri Lanka.

Summary

This study genetically characterizes Cinnamomum species, including Ceylon Cinnamon, using chloroplast genomes, nuclear ITS regions, and mitochondrial genes. It identifies the chloroplast gene ycf1 as a barcode and an indel region in ycf1 that differentiates C. verum from India and Sri Lanka.

Bandaranayake PCG et al (2023).
PLoS One.
PubMed:
37729154

Co-encapsulation of Paprika and Cinnamon Oleoresins by Spray Drying in a Mayonnaise Model: Bioaccessibility of Carotenoids Using in vitro Digestion.

Ferraz MC et al (2023).
Plant Foods Hum Nutr.
PubMed:
37721655

Enhanced mechanical and functional properties of chitosan/polyvinyl alcohol/hydroxypropyl methylcellulose/alizarin composite film by incorporating cinnamon essential oil and tea polyphenols.

Yu H et al (2023).
Int J Biol Macromol.
PubMed:
37714243

Modulation of quorum sensing and biofilm of Gram-negative bacterial pathogens by Cinnamomum zeylanicum L.

Qais FA et al (2023).
Microsc Res Tech.
PubMed:
37660303

Anti-Inflammatory Effects and Macrophage Activation Induced by Bioavailable Cinnamon Polyphenols in Mice.

Song Y et al (2023).
Mol Nutr Food Res.
PubMed:
37658489

Cinnamon modulates the pharmacodynamic & pharmacokinetic of amlodipine in hypertensive rats.

Abdelrahman IA et al (2023).
Saudi Pharm J.
PubMed:
37638214

Investigating the effects of chitosan/ tragacanth gum/ polyvinyl alcohol composite coating incorporated with cinnamon essential oil nanoemulsion on safety and quality features of chicken breast fillets during storage in the refrigerator.

Azadi A et al (2023).
Int J Biol Macromol.
PubMed:
37634769

Effect of Spice Incorporation on Sensory and Physico-chemical Properties of Matcha-Based Hard Candy.

Dhawan K et al (2023).
ACS Omega.
PubMed:
37599978

In Vitro high-throughput toxicological assessment of E-cigarette flavors on human bronchial epithelial cells and the potential involvement of TRPA1 in cinnamon flavor-induced toxicity.

Effah F et al (2023).
Toxicology.
PubMed:
37595738

Use of elemental profiles determined by energy-dispersive X-ray fluorescence and multivariate analyses to detect adulteration in Ceylon cinnamon.

Ghidotti M et al (2023).
Anal Bioanal Chem.
PubMed:
37587311

Anti-Candida and Anti-Leishmanial Activities of Encapsulated Cinnamomum verum Essential Oil in Chitosan Nanoparticles.

Summary

Researchers optimized a technique to encapsulate essential oils in chitosan nanoparticles. The nanoparticles showed strong antibacterial, antifungal, and antiparasitic activity, making them a potential treatment for skin infections.

Essid R et al (2023).
Molecules.
PubMed:
37570651

Influence of diluent on antimicrobial activity of cinnamon bark essential oil vapor against Staphylococcus aureus and Salmonella enterica on a laboratory medium and beef jerky.

Summary

Researchers studied the impact of chemical diluents on the antimicrobial activity of cinnamon bark essential oil vapor, finding that the type of diluent used influences its effectiveness against bacteria. This knowledge is crucial for creating effective decontamination methods for food and food-contact surfaces with essential oils.

Lee T et al (2023).
Food Microbiol.
PubMed:
37567638

The effect of cinnamon consumption on lipid profile, oxidative stress, and inflammation biomarkers in adults: An umbrella meta-analysis of randomized controlled trials.

Summary

Cinnamon has potential health benefits for heart health but the evidence is conflicting. This study aims to provide a definitive answer by analyzing multiple studies on the topic.

Meta-Analysis Immunology
Sarmadi B et al (2023).
Nutr Metab Cardiovasc Dis.
PubMed:
37500345

Encapsulation and delivery systems of cinnamon essential oil for food preservation applications.

Summary

Cinnamon essential oil (CEO) can be used as a natural food preservative, but its low solubility and degradability are limitations. Encapsulation and delivery systems like spray drying and liposomes have been developed to improve CEO's efficiency, enhancing food preservation and extending shelf life.

Zhang W et al (2023).
Adv Colloid Interface Sci.
PubMed:
37480830

The Effect of Cinnamon on Glycolipid Metabolism: A Dose-Response Meta-Analysis of Randomized Controlled Trials.

Meta-Analysis
Yu T et al (2023).
Nutrients.
PubMed:
37447309

Comparison of Chemical Compositions and Antioxidant Activity of Essential Oils from Litsea Cubeba, Cinnamon, Anise, and Eucalyptus.

Liu S et al (2023).
Molecules.
PubMed:
37446712

Synergistic interaction of clove, cinnamon, and eucalyptus essential oils impregnated in cellulose acetate electrospun fibers as antibacterial agents against Staphylococcus aureus.

Amarante JF et al (2023).
Braz J Microbiol.
PubMed:
37391674

Effects of Supplementation with an Herbal Mixture on the Antioxidant Capacity of Milk.

Stobiecka M et al (2023).
Animals (Basel).
PubMed:
37370523

Development of species-specific ISSR-derived SCAR marker for early discrimination between Cinnamomum verum and Cinnamomum cassia.

Gangwar H et al (2023).
Mol Biol Rep.
PubMed:
37306873

Cinnamon Oil-Loaded Nanoliposomes with Potent Antibacterial and Antibiofilm Activities.

Ellboudy NM et al (2023).
Molecules.
PubMed:
37298980

Biochemical, structural characterization and in-vitro evaluation of antioxidant, antibacterial, cytotoxic, and antidiabetic activities of nanosuspensions of Cinnamomum zeylanicum bark extract.

Nawaz A et al (2023).
Front Chem.
PubMed:
37214484

Cinnamaldehyde-Rich Cinnamon Extract Induces Cell Death in Colon Cancer Cell Lines HCT 116 and HT-29.

Summary

This study found that a cinnamon extract containing cinnamaldehyde has anti-cancer effects on colorectal cancer cells by inhibiting cell viability, proliferation, migration, inducing cell cycle arrest, causing mitochondrial stress, and activating apoptotic proteins.

Nile A et al (2023).
Int J Mol Sci.
PubMed:
37175897

A hydroxypropyl methylcellulose/hydroxypropyl starch nanocomposite film reinforced with chitosan nanoparticles encapsulating cinnamon essential oil: Preparation and characterization.

Yu X et al (2023).
Int J Biol Macromol.
PubMed:
37116838

Emulsions containing composite (clove, oregano, and cinnamon) essential oils: Phase inversion preparation, physicochemical properties and antibacterial mechanism.

Hu J et al (2023).
Food Chem.
PubMed:
37105117

Effects of cinnamon essential oil-loaded Pickering emulsion on the structure, properties and application of chayote tuber starch-based composite films.

Wu H et al (2023).
Int J Biol Macromol.
PubMed:
37062380

Nanoencapsulation of Grapefruit Seed Extract and Cinnamon Oil for Oral Health: Preparation, In Vitro, and Clinical Antimicrobial Activities.

Choi YS, Lee JS and Lee HG (2023).
J Agric Food Chem.
PubMed:
36988548

Bio-guided chemical characterization and nano-formulation studies of selected edible volatile oils with potentials antibacterial and anti-SARS-CoV-2 activities.

Summary

Selected essential oils (EOs) with promising antibacterial and antiviral properties against SARS-CoV-2 and bacteria were identified, along with suggested nano-emulsion dosage form. Mechanisms of antiviral activity were explored.

Refaey MS et al (2023).
Arab J Chem.
PubMed:
36969951

Bioactive Compositions of Cinnamon (Cinnamomum verum J. Presl) Extracts and Their Capacities in Suppressing SARS-CoV-2 Spike Protein Binding to ACE2, Inhibiting ACE2, and Scavenging Free Radicals.

Summary

Cinnamon extracts contain bioactive compounds that can inhibit the activity of the virus and increase antioxidant activity, potentially reducing the risk of COVID-19 infection. Ethanol extract showed higher phenolic content and greater free radical scavenging activity compared to water extract, indicating cinnamon's preventive properties against SARS-CoV-2.

Xie Z et al (2023).
J Agric Food Chem.
PubMed:
36940448

Cinnamon Oil Encapsulated with Silica Nanoparticles: Chemical Characterization and Evaluation of Insecticidal Activity Against the Rice Moth, Corcyra cephalonica.

Attia RG et al (2023).
Neotrop Entomol.
PubMed:
36913124

Proposal of novel ApoE4 inhibitors from the natural spice Cinnamon for the treatment of Alzheimer's disease: Ab initio molecular simulations.

Summary

Researchers used molecular techniques to investigate the interactions between apolipoprotein E4 (ApoE4) and cinnamon-derived compounds for developing effective diagnostic strategies and treatment for Alzheimer's disease (AD). Epicatechin was found to have the highest binding affinity to ApoE4 by forming strong hydrogen bonds with specific residues. Adding a hydroxyl group to epicatechin increased its binding affinity to ApoE4, indicating promising therapeutic candidates for AD.

Shaji D et al (2023).
Biophys Chem.
PubMed:
36898350

Exploring Myocardial Ischemia-Reperfusion Injury Mechanism of Cinnamon by Network Pharmacology, Molecular Docking, and Experiment Validation.

Xue T et al (2023).
Comput Math Methods Med.
PubMed:
36873789

Preparation and characterization of functionalized chitosan/polyvinyl alcohol composite films incorporated with cinnamon essential oil as an active packaging material.

Pan Q et al (2023).
Int J Biol Macromol.
PubMed:
36870659

The Application of Cinnamon Twig Extract as an Inhibitor of Listeriolysin O against Listeria monocytogenes Infection.

Hou X et al (2023).
Molecules.
PubMed:
36838612

Investigating the effects of Ceylon cinnamon water extract on HepG2 cells for Type 2 diabetes therapy.

Azimian L et al (2023).
Cell Biochem Funct.
PubMed:
36779418

In Vitro Evaluation of Antiprotozoal Properties, Cytotoxicity Effect and Anticancer Activity of New Essential-Oil Based Phytoncide Mixtures.

Iwiński H et al (2023).
Molecules.
PubMed:
36771061

Cinnamomum verum extract inhibits NOX2/ROS and PKCδ/JNK/AP-1/NF-κB pathway-mediated inflammatory response in PMA-stimulated THP-1 monocytes.

Kim NY et al (2023).
Phytomedicine.
PubMed:
36753827

Cinnamon allergic contact cheilitis.

Bernaola J et al (2023).
Contact Dermatitis.
PubMed:
36753046

Evaluation of on-site testing methods with a novel 3-in-1 miniaturized spectroscopic device for cinnamon screening.

Sudarsh S and Müller-Maatsch J (2023).
Talanta.
PubMed:
36736268

Macroscopic and microscopic study on floral biology and pollination of Cinnamomum verum Blume (Sri Lankan).

Hathurusinghe BM, Pushpakumara DKNG and Bandaranayake PCG (2023).
PLoS One.
PubMed:
36730137

Effects of biochars derived from four crop straws on a Cd-polluted cinnamon soil.

Tong X et al (2023).
Environ Sci Pollut Res Int.
PubMed:
36692727

Edible coating enriched with cinnamon oil reduces the oxidative stress and improves the quality of strawberry fruit stored at room temperature.

Piechowiak T and Skóra B (2023).
J Sci Food Agric.
PubMed:
36683377

Research Note: Responses of broiler chickens to in ovo feeding with clove and cinnamon extract under hot-humid environments.

Akosile OA et al (2023).
Poult Sci.
PubMed:
36621097

Chemopreventive Effect of Cinnamon and Its Bioactive Compounds in a Rat Model of Premalignant Prostate Carcinogenesis.

Gopalakrishnan S et al (2023).
Cancer Prev Res (Phila).
PubMed:
36517462

Rapid and non-destructive cinnamon authentication by NIR-hyperspectral imaging and classification chemometrics tools.

Cruz-Tirado JP et al (2023).
Spectrochim Acta A Mol Biomol Spectrosc.
PubMed:
36512964

Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report.

Patel K, Howard M and Tate B (2023).
Contact Dermatitis.
PubMed:
36461791

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