Cirsium japonicum

Common Names: Japanese thistle

Ethnobotanical Studies

Clinical Trials

A Complex of Cirsium japonicum var. maackii (Maxim.) Matisum. and Thymus vulgaris L. Improves Menopausal Symptoms and Supports Healthy Aging in Women.

Noh YH et al (2022).
J Med Food.
DOI:
10.1089/jmf.2021.K.0127
PubMed:
35320013

Studies

Predicting the distribution of potentially suitable habitat in China for Cirsium japonicum Fisch. ex DC. under future climate scenarios based on the R-optimized MaxEnt model.

Fang HQ et al (2024).
Ecol Evol.
DOI:
10.1002/ece3.11653
PubMed:
38983705

Study on the Compositional Analysis, Extraction Process, and Hemostatic and Anti-Inflammatory Activities of Cirsium japonicum Fisch. ex DC.-Cirsium setosum (Willd.) MB Extracts.

Immunology
Kong F et al (2024).
Molecules.
DOI:
10.3390/molecules29091918
PubMed:
38731410

Potential Antioxidant and Anti-Inflammatory Properties of Polyphenolic Compounds from Cirsium japonicum Extract.

Immunology
Kim HH et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25020785
PubMed:
38255858

Analysis of Genes Associated with Feeding Preference and Detoxification in Various Developmental Stages of Aglais urticae.

Genetics
Xi O, Guo W and Hu H (2024).
Insects.
DOI:
10.3390/insects15010030
PubMed:
38249036

Methanol Extracts from Cirsium japonicum DC. var. australe Kitam. and Their Active Components Reduce Intracellular Oxidative Stress in Caenorhabditis elegans.

Summary

This study explored the antioxidative ability of different parts of DC. var. Kitam. plant. Leaf extracts showed the highest dry weight and all parts contained silychristin and taxifolin. Flower, leaf, and stem extracts reduced oxidative stress, indicating the potential health benefits and use as a silymarin source.

Immunology
Yen PL et al (2023).
Molecules.
DOI:
10.3390/molecules28196923
PubMed:
37836767

Characterization of the glucuronidating pathway of pectolinarigenin, the major active constituent of the Chinese medicine Daji, in humans and its influence on biological activities.

Liu P et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117280
PubMed:
37797876

Protective Effects of Cirsium japonicum var. maackii Flower on Amyloid Beta(25-35)-Treated C6 Glial Cells.

Pang QQ et al (2023).
Life (Basel).
DOI:
10.3390/life13071453
PubMed:
37511827

Chlorogenic Acid of Cirsium japonicum Resists Oxidative Stress Caused by Aging and Prolongs Healthspan via SKN-1/Nrf2 and DAF-16/FOXO in Caenorhabditis elegans.

Cho M et al (2023).
Metabolites.
DOI:
10.3390/metabo13020224
PubMed:
36837843

Purification Process and In Vitro and In Vivo Bioactivity Evaluation of Pectolinarin and Linarin from Cirsium japonicum.

Ye Y et al (2022).
Molecules.
DOI:
10.3390/molecules27248695
PubMed:
36557828

Biologically synthesis of gold nanoparticles using Cirsium japonicum var. maackii extract and the study of anti-cancer properties on AGS gastric cancer cells.

Cancer
Mi XJ et al (2022).
Int J Biol Sci.
DOI:
10.7150/ijbs.77734
PubMed:
36263176

The Current State of Knowledge in Biological Properties of Cirsimaritin.

Review
Benali T et al (2022).
Antioxidants (Basel).
DOI:
10.3390/antiox11091842
PubMed:
36139916

Anti-inflammatory effects of the Aralia elata and Cirsium japonicum in Raw264.7 cells and in vivo colitis model in mice and dogs.

Immunology
Kim R et al (2022).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2022.113186
PubMed:
35643063

Plants with potential anti-ulcerogenic activity and possible mechanism of actions based on their phyto-constitutional profile.

Review
Keny ES and Kale PP (2022).
J Complement Integr Med.
DOI:
10.1515/jcim-2021-0264
PubMed:
35152595

Cirsium japonicum var. Maackii Improves Cognitive Impairment under Amyloid Beta(25-35)-Induced Alzheimer's Disease Model.

Summary

Researchers studied the protective effects of an herbal medicine called CJM on mice with Alzheimer's disease (AD). They focused on the ethyl acetate fraction from CJM (ECJM), which has anti-inflammatory properties, and found that it improved the mice's spatial and object recognition memory, as well as their learning and memory abilities. The ECJM also inhibited lipid peroxidation and nitric oxide production, indicating that it improves cognitive impairment by reducing oxidative stress. This study suggests that CJM could be used as a treatment for AD and may have potential as a functional food material.

Neuroscience
Pang QQ et al (2022).
Biomed Res Int.
DOI:
10.1155/2022/4513998
PubMed:
35036433

Efficient discovery of potential inhibitors for SARS-CoV-2 3C-like protease from herbal extracts using a native MS-based affinity-selection method.

Summary

Scientists developed a method for quickly screening active compounds from traditional Chinese medicines (TCMs) that may be effective against the 3C-like protease of SARS-CoV-2. Six common herbs were investigated, resulting in three potential noncovalent inhibitors: baicalein, scutellarein, and ganhuangenin, with IC values of 0.94, 3.02, and 0.84 μM, respectively. This study is promising for finding small molecule leads in TCMs to treat COVID-19.

COVID-19
Zhu D et al (2022).
J Pharm Biomed Anal.
DOI:
10.1016/j.jpba.2021.114538
PubMed:
34929567

Cirsium japonicum var. maackii and apigenin block Hif-2α-induced osteoarthritic cartilage destruction.

Arthritis
Cho C et al (2019).
J Cell Mol Med.
DOI:
10.1111/jcmm.14418
PubMed:
31148341

Cytotoxic phenylpropanoid glycosides from Cirsium japonicum.

Phytochemistry
Shang DL, Ma QG and Wei RR (2016).
J Asian Nat Prod Res.
PubMed:
27308841

Effects and treatment methods of acupuncture and herbal medicine for premenstrual syndrome/premenstrual dysphoric disorder: systematic review.

Review
Jang SH, Kim DI and Choi MS (2014).
BMC Complement Altern Med.
DOI:
10.1186/1472-6882-14-11
PubMed:
24410911

Cirsium japonicum flavones enhance adipocyte differentiation and glucose uptake in 3T3-L1 cells.

Liao Z, Wu Z and Wu M (2012).
Biol Pharm Bull.
PubMed:
22687475