Cissus quadrangularis

Common Names: veldt-grape

Ethnobotanical Studies

Studies

Endophytic fungi from Cissus quadrangularis plant a promising source of bioactive compounds.

Awari VS et al (2024).
Braz J Microbiol.
PubMed:
39207638

Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice.

Summary

Researchers studied the effects of CQR-300 from vining plant on T2DM in mutated mice. CQR-300 reduced blood glucose, insulin levels, inhibited gluconeogenesis, lipogenesis, and oxidative stress. Potential as T2DM supplement.

Kim JW et al (2024).
Front Pharmacol.
PubMed:
39050759

Phytofabrication of biocompatible chitosan-based ZnO nanocomposite aided by Cissus quadrangularis extract enriched with antimicrobial and antioxidant potential.

Summary

Tossers made a chitosan-based ZnO nanocomposite with CQ plant extract. It has potent antimicrobial, antioxidant properties, is biocompatible, and effective against S. aureus, E. coli. Potential for advanced medical applications.

Bharathi VU and Thambidurai S (2024).
Int J Biol Macromol.
PubMed:
38820903

Green Synthesis and the Evaluation of Osteogenic Potential of Novel Europium-Doped-Monetite Calcium Phosphate by Cissus quadrangularis.

Suresh N and Kaarthikeyan G (2024).
Cureus.
PubMed:
38807788

Effects of Cissus quadrangularis L. Powder on Proximate Composition, Physicochemical and Textural Properties of Tteokgalbi.

Lee JJ et al (2024).
Food Sci Anim Resour.
PubMed:
38765287

Self Emulsifying Delivery System of Cissus quadrangularis: Evidence of Enhanced Efficacy and Promising Pharmacokinetic Profile in the Management of Osteoporosis.

Garg J et al (2024).
AAPS PharmSciTech.
PubMed:
38730121

Development of a Cissus quadrangularis-Doped Extracellular Matrix and a Hyaluronic Acid-Incorporated Scaffold for Periodontal Regeneration: An In Vitro Study.

Ganesh S B et al (2024).
Cureus.
PubMed:
38646344

Down-conversion luminescence nanocomposites based on nitrogen-doped carbon quantum dots@bioplastic for applications in optical displays, LEDs and UVC tubes.

Dutt Sharma V et al (2024).
Spectrochim Acta A Mol Biomol Spectrosc.
PubMed:
38402703

Analyzing the Antihyperglycemic Effect of Cissus quadrangularis and Bacopa monnieri on 3T3-L1 Cell Lines.

R K et al (2024).
Cureus.
PubMed:
38380214

Plant-derived natural medicines for the management of osteoporosis: A comprehensive review of clinical trials.

Summary

This study reviewed clinical evidence on using herbal medicine to manage osteoporosis, which is a chronic skeletal disease causing low bone density and increased fracture risk.

Review Arthritis
Karimi SM, Bayat M and Rahimi R (2023).
J Tradit Complement Med.
PubMed:
38223808

Influence of chitosan and Cissus quandrangularis coating on osseointegration in titanium implants in rabbits: A preclinical in vivo study.

Roy TR et al (2023).
J Stomatol Oral Maxillofac Surg.
PubMed:
38065438

Establishing the Callus-Based Isolation of Extracellular Vesicles from Cissus quadrangularis and Elucidating Their Role in Osteogenic Differentiation.

Gupta R et al (2023).
J Funct Biomater.
PubMed:
37998109

Potential Curative Effects of Aqueous Extracts of Cissus quadrangularis (Vitaceae) and Jatropha gossypiifolia (Euphorbiaceae) on Acetaminophen-Induced Liver Injury in Mice.

Guemmogne Temdie RJ et al (2023).
Curr Ther Res Clin Exp.
PubMed:
37869400

Ethnoveterinary Study of Plant-Based Remedies for Treating Diseases in Small Ruminants in Maputo Province, Mozambique.

Summary

Researchers studied the use of plant-based remedies and other treatments for livestock diseases in Mozambique. They found 38 common remedies and emphasized the importance of preserving traditional knowledge for sustainable livestock management.

Barbosa FMA et al (2023).
Evid Based Complement Alternat Med.
PubMed:
37842333

In-vitro Antioxidant, In-vitro and In-silico Ovarian Anticancer Activity (Ovarian Cancer Cells-PA1) and Phytochemical Analysis of Cissus quadrangularis L. Ethanolic Extract.

Summary

Research shows that Cissus quadrangularis, a plant, holds medicinal properties. This information is relevant for making informed decisions in the field of traditional medicine.

Zhao X et al (2023).
Comb Chem High Throughput Screen.
PubMed:
37818574

Lupenone-Rich Fraction Derived from Cissus quadrangularis L. Suppresses Lipid Accumulation in 3T3-L1 Adipocytes.

Lakthan T et al (2023).
Life (Basel).
PubMed:
37629581

Cissus quadrangularis L extract-loaded tricalcium phosphate reinforced natural polymer composite for guided bone regeneration.

Liao L et al (2023).
J Mater Sci Mater Med.
PubMed:
37466722

Fabrication of chitosan nanocomposites loaded with biosynthetic metallic nanoparticles and their therapeutic investigation.

Gracias S et al (2023).
Environ Res.
PubMed:
37437861

A study on antimicrobial and anticancer properties of Cissus quadrangulris using lung cancer cell line.

Summary

A study was conducted to analyze the medicinal properties of the stem extract from the Cissus quadrangularis plant. The extract showed antimicrobial activity against various microorganisms and displayed potential in inhibiting the growth of A549 human lung cancer cells. In addition, the extract exhibited a dose-dependent reduction in lung cancer cell viability. Further analysis revealed that the IC50 dose, which inhibits 50% of cell growth, was achieved at a concentration of 65.2 μg/ml. These findings suggest that the Cissus quadrangularis stem extract may have potential as a natural anti-cancer agent.

Payani S et al (2023).
Cancer Treat Res Commun.
PubMed:
37379774

Simultaneous Estimation of Quercetin and trans-Resveratrol in Cissus quadrangularis Extract in Rat Serum Using Validated LC-MS/MS Method: Application to Pharmacokinetic and Stability Studies.

Dadge SD et al (2023).
Molecules.
PubMed:
37375211

Decoding the complete chloroplast genome of Cissus quadrangularis: insights into molecular structure, comparative genome analysis and mining of mutational hotspot regions.

Senapati A et al (2023).
Physiol Mol Biol Plants.
PubMed:
37363414

Development of Cissus quadrangularis-Loaded POSS-Reinforced Chitosan-Based Bilayer Sponges for Wound Healing Applications: Drug Release and In Vitro Bioactivity.

Aker SD, Tamburaci S and Tihminlioglu F (2023).
ACS Omega.
PubMed:
37305322

Biofunctionalization with Cissus quadrangularis Phytobioactives Accentuates Nano-Hydroxyapatite Based Ceramic Nano-Cement for Neo-Bone Formation in Critical Sized Bone Defect.

Gupta A et al (2023).
Int J Pharm.
PubMed:
37302672

The effect of Cissus quadrangularis Salisb. extract on maturation of rat mesenchymal stem cells.

Eriani K et al (2023).
Braz J Biol.
PubMed:
37255198

Comparison of Teriparatide and Combination of Cissus Quadrangularis and Dalbergia Sissoo on Bone Healing Against the Control Group in Maxillofacial Fractures: A Randomized Open-label Control Trial.

Pg G et al (2023).
Craniomaxillofac Trauma Reconstr.
PubMed:
36824186

A comprehensive review on clinically proven medicinal plants in the treatment of overweight and obesity, with mechanistic insights.

Summary

This review examines how medicinal plants can help manage obesity, which is a growing global health problem associated with serious health conditions.

Review Obesity
Aziz MA et al (2023).
Heliyon.
PubMed:
36816319

Exosome-Functionalized, Drug-Laden Bone Substitute along with an Antioxidant Herbal Membrane for Bone and Periosteum Regeneration in Bone Sarcoma.

Gupta S et al (2023).
ACS Appl Mater Interfaces.
PubMed:
36749176

Cissus quadrangularis (Hadjod) Inhibits RANKL-Induced Osteoclastogenesis and Augments Bone Health in an Estrogen-Deficient Preclinical Model of Osteoporosis Via Modulating the Host Osteoimmune System.

Azam Z et al (2023).
Cells.
PubMed:
36672152

Evaluation of mutagenic, cytotoxic, mitochondrial dysfunction, apoptotic activity, and acute toxicity of ethanolic extract of Cissus quadrangularis.

Syed AA et al (2023).
Toxicology.
PubMed:
36370889

Identification of Bioactive Pentacyclic Triterpenoids and Fatty Acid Derivatives from Cissus quadrangularis and C. rotundifolia Through Untargeted Metabolite Profiling.

Purohit S, Bohra MK and Jain R (2023).
Appl Biochem Biotechnol.
PubMed:
35511385

Value addition of Cissus quadrangularis stem powder in Ethiopian flat bread: Injera and its effect on Nutritional composition, Sensory attributes and Microbial load.

Kelbore T, Yilma B and Srinivasan B (2022).
J Food Sci Technol.
PubMed:
35250068

Antibacterial Activity of Some Medicinal Plants in Al Baha Region, Saudi Arabia, Against Carcinogenic Bacteria Related to Gastrointestinal Cancers.

Alzandi AA et al (2023).
J Gastrointest Cancer.
PubMed:
34988907

Cissus quadrangularis L: A comprehensive multidisciplinary review.

Review
Bafna PS et al (2021).
J Ethnopharmacol.
PubMed:
34181958

Effectiveness of herbal medicines for weight loss: A systematic review and meta-analysis of randomized controlled trials.

Meta-Analysis
Maunder A et al (2020).
Diabetes Obes Metab.
PubMed:
31984610

Efficacy and Safety of Cissus quadrangularis L. in Clinical Use: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Meta-Analysis
Sawangjit R et al (2017).
Phytother Res.
PubMed:
28165166

A Review of Natural Stimulant and Non-stimulant Thermogenic Agents.

Review
Stohs SJ and Badmaev V (2016).
Phytother Res.
PubMed:
26856274

Hepatoprotective Effect of Cissus quadrangularis Stem Extract Against Rifampicin-induced Hepatotoxicity in Rats.

Swamy AH et al (2012).
Indian J Pharm Sci.
PubMed:
23326004

A review and evaluation of the efficacy and safety of Cissus quadrangularis extracts.

Review
Stohs SJ and Ray SD (2013).
Phytother Res.
PubMed:
22976133