Clematis chinensis

Ethnobotanical Studies

Gongcheng County, Guangxi, China

Uses: Bruise, rheumatic bone pain, hyperostosis, fallopian tube obstruction

DOI:: 10.1186/s13002-022-00544-6
PubMed:: 35729593

Yi people, Mile, Yunnan, China

Uses: Lumbosacral pain, traumatic injury

DOI:: 10.1186/s13002-024-00656-1
PubMed:: 38395900

Studies

Phenolic glycosides and indole alkaloids isolated from the roots and rhizomes of Clematis chinensis and their anti-inflammatory activity.

Summary

Six unknown compounds were discovered in Clematis chinensis, along with known compounds. Some compounds showed significant anti-inflammatory activity, reducing the secretion of inflammatory factors by inhibiting the NF-κB signaling pathway.

Immunology Phytochemistry

Jiang HB et al (2023).; Phytochemistry.
DOI:: 10.1016/j.phytochem.2023.113832
PubMed:: 37598991

The complete chloroplast genome sequence of Clematis chinensis Osbeck.

Genetics

Guo S et al (2022).; Mitochondrial DNA B Resour.
DOI:: 10.1080/23802359.2022.2148823
PubMed:: 36451970

Huangqin Qingre Qubi Capsule inhibits RA pathology by binding FZD8 and further inhibiting the activity of Wnt/β-catenin signaling pathway.

Zhou W et al (2023).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2022.115886
PubMed:: 36336221

Clematichinenoside AR inhibits the pathology of rheumatoid arthritis by blocking the circPTN/miR-145-5p/FZD4 signal axis.

Arthritis

Wang X et al (2022).; Int Immunopharmacol.
DOI:: 10.1016/j.intimp.2022.109376
PubMed:: 36279670

The multi-omics and analysis to reveal thermal processing enhanced anti-rheumatoid arthritis efficacy of Radix Clematidis in rats.

Arthritis

Jiang SQ et al (2022).; J Pharm Biomed Anal.
DOI:: 10.1016/j.jpba.2022.114760
PubMed:: 35421778

Thermal and wine processing enhanced Clematidis Radix et Rhizoma ameliorate collagen Ⅱ induced rheumatoid arthritis in rats.

Arthritis

Jiang SQ et al (2022).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2022.114993
PubMed:: 35032583

Two new terpenes from the aerial parts of Clematis chinensis Osbeck.

Phytochemistry

Ye S et al (2022).; Nat Prod Res.
DOI:: 10.1080/14786419.2021.1889541
PubMed:: 33615918

Uses, chemical compositions, pharmacological activities and toxicology of Clematidis Radix et Rhizome- a Review.

Review

Lin TF et al (2021).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2021.113831
PubMed:: 33476714

Clematichinenoside AR Alleviates Foam Cell Formation and the Inflammatory Response in Ox-LDL-Induced RAW264.7 Cells by Activating Autophagy.

Immunology

Diao Y et al (2021).; Inflammation.
DOI:: 10.1007/s10753-020-01375-x
PubMed:: 33151398

10.

Clemaichinenoside protects renal tubular epithelial cells from hypoxia/reoxygenation injury in vitro through activating the Nrf2/HO-1 signalling pathway.

Feng J et al (2020).; Clin Exp Pharmacol Physiol.
DOI:: 10.1111/1440-1681.13219
PubMed:: 31785117

11.

A botanical drug composed of three herbal materials attenuates the sensorimotor gating deficit and cognitive impairment induced by MK-801 in mice.

Summary

Researchers investigated the effects of a botanical drug derived from three plants on schizophrenia-like behaviors induced by MK-801. The drug has been used to treat rheumatoid arthritis in Korea. The study found that the herbal complex extract improved cognitive function and reduced the symptoms of schizophrenia-like behaviors in mice. These results suggest that the botanical drug could potentially be used to treat schizophrenia in humans.

Neuroscience