Colchicum autumnale

Common Names: autumn crocus

Ethnobotanical Studies

Studies

Inhibition of CYP1A1 Alleviates Colchicine-Induced Hepatotoxicity.

Huang R et al (2024).
Toxins (Basel).
DOI:
10.3390/toxins16010035
PubMed:
38251251

Comprehending interaction mechanism of natural actives of Colchicum autumnale L. for rheumatoid arthritis using integrative chemoinformatic approaches.

Summary

This research investigates natural compounds from L. for their potential use in treating rheumatoid arthritis (RA). Through molecular docking and simulations, compounds β-sitosterol and colchicine show promising binding energies and stability, suggesting they could be effective anti-RA medications. Care because new treatment options for RA could be discovered.

Arthritis
H S S et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2294177
PubMed:
38116745

Colchicum autumnale intoxications: experience of the Poisons Information Centre, Austria 2002-2018.

Arif T et al (2023).
Clin Toxicol (Phila).
DOI:
10.1080/15563650.2023.2272572
PubMed:
37917169

Evaluation of anticancer effect of colchicum autumnale L. Corm on breast cancer cell.

Summary

Study evaluated anticancer effect of colchicum autumnale L. Corm on breast cancer cells. Medicinal plants could potentially prevent and inhibit breast cancer. Important for lab decisions on cancer research.

Cancer
Falahianshafiei S et al (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-04189-0
PubMed:
37805533

Beware of accidental ingestion of Colchicum autumnale mistaken for Allium victorialis.

Nara T et al (2023).
Acute Med Surg.
DOI:
10.1002/ams2.854
PubMed:
37261376

Inhibition of STAT3 phosphorylation by colchicine regulates NLRP3 activation to alleviate sepsis-induced acute lung injury.

Immunology
Liu Y et al (2023).
Inflammopharmacology.
DOI:
10.1007/s10787-023-01199-9
PubMed:
37115345

No physiological costs of dual sequestration of chemically different plant toxins in the milkweed bug Spilostethus saxatilis (Heteroptera: Lygaeidae).

Espinosa Del Alba L and Petschenka G (2023).
J Insect Physiol.
DOI:
10.1016/j.jinsphys.2023.104508
PubMed:
37011856

Toxicity Profiling and Antihyperuricemic Activity of Goubion: A Polyherbal Formulation.

Sadia H et al (2023).
Evid Based Complement Alternat Med.
DOI:
10.1155/2023/7088628
PubMed:
36846052

Design, synthesis and biological evaluation of a novel colchicine-magnolol hybrid for inhibiting the growth of Lewis lung carcinoma in Vitro and in Vivo.

Li Z et al (2022).
Front Chem.
DOI:
10.3389/fchem.2022.1094019
PubMed:
36583151

Colchicine of Colchicum autumnale, A Traditional Anti-Inflammatory Medicine, Induces Apoptosis by Activation of Apoptotic Genes and Proteins Expression in Human Breast (MCF-7) and Mouse Breast (4T1) Cell Lines.

GeneticsImmunology
Adham Foumani E et al (2022).
Cell J.
DOI:
10.22074/cellj.2022.8290
PubMed:
36377214

First report of meadow saffron breaking virus on wild Colchicum autumnale from a stricly protected Natura2000 site at a Hungarian National Park.

Ágoston J et al (2022).
Plant Dis.
DOI:
10.1094/PDIS-08-22-1787-PDN
PubMed:
36320137

Functional characterization of a Colchicum autumnale L. double-bond reductase (CaDBR1) in colchicine biosynthesis.

Review
Xiong Z et al (2022).
Planta.
DOI:
10.1007/s00425-022-04003-0
PubMed:
36214872

Determination of Colchicine in Pharmaceutical Formulations, Traditional Extracts, and Ultrasonication-Based Extracts of Colchicum autumnale Pleniflorum (L.) Using Regular and Greener HPTLC Approaches: A Comparative Evaluation of Validation Parameters.

Alqarni MH et al (2022).
Plants (Basel).
DOI:
10.3390/plants11131767
PubMed:
35807719

Multidirectional analysis for a colchicine poisoning case revealed detail cause of death and its mechanism.

Okuda K et al (2022).
Leg Med (Tokyo).
DOI:
10.1016/j.legalmed.2022.102092
PubMed:
35643042

Sequestration of Defenses against Predators Drives Specialized Host Plant Associations in Preadapted Milkweed Bugs (Heteroptera: Lygaeinae).

Petschenka G et al (2022).
Am Nat.
DOI:
10.1086/719196
PubMed:
35580225

Acaricidal Activity of Colchicum autumnale (autumn crocus) Extract against Hyalomma spp. In vitro.

Norouzi R et al (2021).
Arch Razi Inst.
DOI:
10.22092/ari.2020.128349.1411
PubMed:
34223728

Observations on the Use of Colchicum Autumnale in the Treatment of Gout, &c.

Review
(1826).
Med Chir Rev.
PubMed:
29917753

Modeling the Colchicum autumnale Tubulin and a Comparison of Its Interaction with Colchicine to Human Tubulin.

Spasevska I et al (2017).
Int J Mol Sci.
DOI:
10.3390/ijms18081676
PubMed:
28767055

[Colchicum autumnale].

Miyazaki S et al (2014).
Chudoku Kenkyu.
PubMed:
24724352

Colchicum autumnale agglutinin activates all murine T-lymphocytes but does not induce the proliferation of all activated cells.

Immunology
Bemer V et al (1996).
Cell Immunol.
PubMed:
8806807

Colchicine poisoning.

Review
Hood RL et al (1994).
J Emerg Med.
PubMed:
8207152