Cucurbita moschata

Common Names: butternut squash, calabaza, Dickinson pumpkin, golden cushaw, Kentucky field pumpkin, large cheese pumpkin, Long Island cheese pumpkin, neck pumpkin, Seminole pumpkin, Tahitian squash, Tennessee sweet potato, West Indian pumpkin

Ethnobotanical Studies

Clinical Trials

Impact of cucurbit crop management techniques on the foraging behavior of honeybees and hoverflies in Morogoro, Tanzania.

Rweyemamu EW et al (2024).
BMC Ecol Evol.
DOI:
10.1186/s12862-024-02202-9
PubMed:
38233768

Studies

Simultaneous determination of cucurbitacins B, D, and E in Cucurbita seed oils by HPLC-DAD.

Goya-Jorge E, Jorge-Rodríguez ME and Saucedo-Hernández Y (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2394097
PubMed:
39234765

Combining ability analysis of Cucurbita moschata D. in Côte d'Ivoire and classification of promising lines based on their gca effects.

Kouago BA et al (2024).
PLoS One.
DOI:
10.1371/journal.pone.0305798
PubMed:
39172947

Cloning and Direct Evolution of a Novel 7-O-Glycosyltransferase from Cucurbita moschata and Its Application in the Efficient Biocatalytic Synthesis of Luteolin-7-O-glucoside.

Lu C et al (2024).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.4c04444
PubMed:
39161099

In Vitro Studies of Pumpkin (Cucurbita moschata var. Kashi Harit) Seed Protein Fraction(s) to Evaluate Anticancer and Antidiabetic Properties.

Summary

Pumpkin seed proteins have potential anticancer and antidiabetic properties. Extracts showed cytotoxic effects on cancer cells and improved insulin secretion in pancreas cells. Promising for cancer and diabetes management.

CancerDiabetes
Vinayashree S et al (2024).
Plant Foods Hum Nutr.
DOI:
10.1007/s11130-024-01205-7
PubMed:
38951376

Development and Evaluation of Nutritional and Quality Standard of Beef Burger Supplemented with Pumpkin (Cucurbita moschata) Seed Flour.

de Melo FABR et al (2024).
Foods.
DOI:
10.3390/foods13111702
PubMed:
38890933

Archaeobotanical evidence supports indigenous cucurbit long-term use in the Mesoamerican Neotropics.

Domic AI et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-60723-1
PubMed:
38740801

Two Novel Angiotensin-Converting Enzyme (ACE) Inhibitory and ACE2 Upregulating Peptides from the Hydrolysate of Pumpkin (Cucurbita moschata) Seed Meal.

Summary

Researchers used pumpkin seed meal to create ACE inhibitory and ACE2 upregulating peptides. Two identified peptides showed significant ACE inhibition activity and were stable during digestion. These peptides have potential as antihypertensive agents.

COVID-19
Li X et al (2024).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.4c00609
PubMed:
38689562

Genome‑wide analysis of the MYB gene family in pumpkin.

Summary

Scientists identified and analyzed genes in pumpkins, finding them highly conserved and non-uniformly distributed across chromosomes. They respond to hormones and stress, with potential roles in growth and stress regulation. This study lays groundwork for future pumpkin research.

Genetics
Xu M et al (2024).
PeerJ.
DOI:
10.7717/peerj.17304
PubMed:
38680887

Comparing the differences in quality profiles and antioxidant activity in seven pumpkin cultivars (Cucurbita moschata and Cucurbita maxima) at harvest and during postharvest storage.

Immunology
Xu Y et al (2024).
Food Chem X.
DOI:
10.1016/j.fochx.2024.101383
PubMed:
38665625

Inclusion of chia seeds (Salvia hispanica L.) and pumpkin seeds (Cucurbita moschata) in dairy sheep diets.

Robles Jimenez LE et al (2024).
PLoS One.
DOI:
10.1371/journal.pone.0300864
PubMed:
38635849

Effects of Cucurbita Moschata squash (Butternut) seed paste in improving zinc and iron status in children attending Early Childhood Development centres in Limpopo province, South Africa.

Motadi SA et al (2024).
PLoS One.
DOI:
10.1371/journal.pone.0300845
PubMed:
38635826

Optimization of a gluten-free sponge cake formulation based on quinoa, oleaster, and pumpkin flour using mixture design methodology.

Madadi M et al (2024).
Food Sci Nutr.
DOI:
10.1002/fsn3.3977
PubMed:
38628209

Green Extraction of Natural Colorants from Food Residues: Colorimetric Characterization and Nanostructuring for Enhanced Stability.

Lauria VBM and Silva LP (2024).
Foods.
DOI:
10.3390/foods13060962
PubMed:
38540952

Molecular markers associated with resistance to squash leaf curl China virus and tomato leaf curl New Delhi virus in tropical pumpkin (Cucurbita moschata Duchesne ex Poir.) breeding line AVPU1426.

Schafleitner R et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-57348-9
PubMed:
38514827

Biosynthesis, Characterization, and Biomedical Applications of Gold Nanoparticles with Cucurbita moschata Duchesne Ex Poiret Peel Aqueous Extracts.

Kaval U and Hoşgören H (2024).
Molecules.
DOI:
10.3390/molecules29050923
PubMed:
38474434

Artificial neural networks optimize the establishment of a Brazilian germplasm core collection of winter squash (Cucurbita moschata D.).

Gomes RS et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-54818-y
PubMed:
38467669

Middle Eastern Plants with Potent Cytotoxic Effect Against Lung Cancer Cells.

Summary

Researchers screened Middle Eastern plants for cytotoxic effects against lung cancer cell lines. Some extracts showed potent efficacy in inducing apoptosis in cancer cells, suggesting potential as alternative cancer treatments. Additional research into these plant extracts could lead to new cancer therapies.

Cancer
Nazeam JA and El-Emam SZ (2024).
J Med Food.
DOI:
10.1089/jmf.2022.0098
PubMed:
38381516

Transcriptomic analysis reveals the molecular basis of photoperiod-regulated sex differentiation in tropical pumpkins (Cucurbita moschata Duch.).

Xue S et al (2024).
BMC Plant Biol.
DOI:
10.1186/s12870-024-04777-3
PubMed:
38317069

Toxicological evaluation of a pumpkin-derived pectin preparation: in vitro genotoxicity studies and a 13-week oral toxicity study in Sprague-Dawley rats.

Kleijn AF et al (2024).
Toxicol Res (Camb).
DOI:
10.1093/toxres/tfae004
PubMed:
38274036

Bioaccessibility of Carotenoids and Polyphenols in Organic Butternut Squash (Cucurbita moschata): Impact of Industrial Freezing Process.

Kamiloglu S et al (2024).
Foods.
DOI:
10.3390/foods13020239
PubMed:
38254540

Effects of including of Japanese Pumpkin Seeds and Pomace in the Diets of Pacific White Shrimp (Penaeus vannamei).

Zancan TD et al (2023).
Animals (Basel).
DOI:
10.3390/ani13223480
PubMed:
38003098

Natural variation in the promoter of FLOWERING LOCUS T-LIKE 2 in pumpkin (Cucurbita moschata Duch.) is associated with flowering time under short-day conditions.

Zhao H et al (2023).
Plant Cell Environ.
DOI:
10.1111/pce.14766
PubMed:
37969013

Further Molecular Diagnosis Determines Lack of Evidence for Real Seed Transmission of Tomato Leaf Curl New Delhi Virus in Cucurbits.

Sáez C et al (2023).
Plants (Basel).
DOI:
10.3390/plants12213773
PubMed:
37960129

Effect of Bioactive Compounds from Pumpkin Powder on the Quality and Textural Properties of Shortbread Cookies.

Ghendov-Mosanu A et al (2023).
Foods.
DOI:
10.3390/foods12213907
PubMed:
37959025

A Genome-Wide Identification and Comparative Analysis of the Heavy-Metal-Associated Gene Family in Cucurbitaceae Species and Their Role in Cucurbita pepo under Arsenic Stress.

Genetics
Flores-Iga G et al (2023).
Genes (Basel).
DOI:
10.3390/genes14101877
PubMed:
37895226

Analyzing genomic variation in cultivated pumpkins and identification of candidate genes controlling seed traits.

Summary

This study analyzed pumpkin breeding materials and identified genetic loci controlling seed traits. It found significant variations and mapped 15 loci associated with pumpkin seed traits, aiding commercial breeding and improving seed traits.

Genetics
Lee CY et al (2023).
Plant Genome.
DOI:
10.1002/tpg2.20393
PubMed:
37776006

In Vivo, In Vitro and In Silico Study of Cucurbita moschata Flower Extract: A Promising Source of Natural Analgesic, Anti-Inflammatory, and Antibacterial Agents.

Summary

This study found that a flower extract has analgesic, anti-inflammatory, and antibacterial properties. It also identified potential therapeutic compounds and supports the traditional use of these flowers for pain and inflammation.

ImmunologyPain
Hossain MR et al (2023).
Molecules.
DOI:
10.3390/molecules28186573
PubMed:
37764349

Chemical and physical properties of winter squash and their correlation with liking of their sensory attributes.

Moreno SR et al (2023).
J Food Sci.
DOI:
10.1111/1750-3841.16771
PubMed:
37755684

A pathogenesis-related protein 1 of Cucurbita moschata responds to powdery mildew infection.

Guo WL et al (2023).
Front Genet.
DOI:
10.3389/fgene.2023.1168138
PubMed:
37593115

Evaluation of Antidiabetic and Antioxidant Activities of Fruit Pulp Extracts of Cucurbita moschata Duchesne and Cucurbita maxima Duchesne.

DiabetesImmunology
Suwannapong A, Talubmook C and Promprom W (2023).
ScientificWorldJournal.
DOI:
10.1155/2023/1124606
PubMed:
37398913

Genome-wide characterization of long terminal repeat retrotransposons provides insights into trait evolution of four cucurbit species.

Genetics
Liu HN et al (2023).
Funct Integr Genomics.
DOI:
10.1007/s10142-023-01128-7
PubMed:
37393305

Identification of a Major-Effect Quantitative Trait Loci Associated with Begomovirus Resistance in Cucurbita moschata.

Verma N et al (2023).
Phytopathology.
DOI:
10.1094/PHYTO-07-22-0240-FI
PubMed:
37352896

Impact of Cucurbita moschata resistant rootstocks on Cucumis sativus fruit and Meloidogyne incognita development.

Zhen X et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-02-22-0319-RE
PubMed:
37272044

Alternative Splicing of NAC Transcription Factor Gene CmNST1 Is Associated with Naked Seed Mutation in Pumpkin, Cucurbita moschata.

Genetics
Shen Q and Weng Y (2023).
Genes (Basel).
DOI:
10.3390/genes14050962
PubMed:
37239322

Comprehensive analyses of microtubule-associated protein MAP65 family genes in Cucurbitaceae and CsaMAP65s expression profiles in cucumber.

Genetics
Liang M et al (2023).
J Appl Genet.
DOI:
10.1007/s13353-023-00761-z
PubMed:
37219731

First report of tomato leaf curl New Delhi virus infecting several cucurbit plants in China.

Gu Q et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-01-23-0180-PDN
PubMed:
37081636

Pro‑differentiating compounds for human intervertebral disc cells are present in Violina pumpkin leaf extracts.

Lambertini E et al (2023).
Int J Mol Med.
DOI:
10.3892/ijmm.2023.5242
PubMed:
37026516

Genome-wide identification of NHX (Na(+)/H(+) antiporter) gene family in Cucurbita L. and functional analysis of CmoNHX1 under salt stress.

Genetics
Shen C et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1136810
PubMed:
36998676

Understanding the Impact of High-Pressure Treatment on Physico-Chemical, Microstructural, and Microbiological Aspects of Pumpkin Cubes.

Rinaldi M et al (2023).
Foods.
DOI:
10.3390/foods12061280
PubMed:
36981207

Genome-wide characterization and expression of DELLA genes in Cucurbita moschata reveal their potential roles under development and abiotic stress.

Genetics
Luo W et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1137126
PubMed:
36909418

Assessment of the variability of the morphological traits and differentiation of Cucurbita moschata in Cote d'Ivoire.

Seka D, Kouago BA and Bonny BS (2023).
Sci Rep.
DOI:
10.1038/s41598-023-30295-7
PubMed:
36878922

Effects of different planting distances and fertilizer use on the remediation of farmland contaminated with Cd by intercropping Cucurbita moschata and Amaranthus hypochondriacus L.

Chen W et al (2023).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-023-26076-4
PubMed:
36854940

Genome-Wide Identification of BES1 Gene Family in Six Cucurbitaceae Species and Its Expression Analysis in Cucurbita moschata.

Genetics
Xu M et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24032287
PubMed:
36768611

CUCUME: An RNA methylation database integrating systemic mRNAs signals, GWAS and QTL genetic regulation and epigenetics in different tissues of Cucurbitaceae.

Genetics
Li X et al (2023).
Comput Struct Biotechnol J.
DOI:
10.1016/j.csbj.2023.01.012
PubMed:
36698975

Comparative assessment of Cucurbita moschata seed polypeptides toward the protection of human skin cells against oxidative stress-induced aging.

Liu C et al (2023).
Front Nutr.
DOI:
10.3389/fnut.2022.1091499
PubMed:
36687694

Analysis of bioactive compounds present in different crude extracts of Benincasa hispida and Cucurbita moschata seeds by gas chromatography-mass spectrometry.

Phytochemistry
Muzahid AA et al (2022).
Heliyon.
DOI:
10.1016/j.heliyon.2022.e12702
PubMed:
36685362

Grafting to Manage Infections of the Emerging Tomato Leaf Curl New Delhi Virus in Cucurbits.

Mastrochirico M, Spanò R and Mascia T (2022).
Plants (Basel).
DOI:
10.3390/plants12010037
PubMed:
36616164

Abscisic Acid Mediates Salicylic Acid Induced Chilling Tolerance of Grafted Cucumber by Activating H(2)O(2) Biosynthesis and Accumulation.

Zhang Y et al (2022).
Int J Mol Sci.
DOI:
10.3390/ijms232416057
PubMed:
36555697

Effect of Leaf Trichomes in Different Species of Cucurbitaceae on Attachment Ability of the Melon Ladybird Beetle Chnootriba elaterii.

Saitta V et al (2022).
Insects.
DOI:
10.3390/insects13121123
PubMed:
36555032

Unconventional Extraction of Total Non-Polar Carotenoids from Pumpkin Pulp and Their Nanoencapsulation.

Pinna N et al (2022).
Molecules.
DOI:
10.3390/molecules27238240
PubMed:
36500333

Phosphine gas in the dark induces severe phytotoxicity in Arabidopsis thaliana by increasing a hypoxia stress response and disrupting the energy metabolism: Transcriptomic approaches.

Kim K et al (2023).
J Hazard Mater.
DOI:
10.1016/j.jhazmat.2022.130141
PubMed:
36241498

Characterization of cultivated pumpkin (Cucurbita moschata Duchesne) landraces for genotypic variance, heritability and agro-morphological traits.

Ezin V, Gbemenou UH and Ahanchede A (2022).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2022.02.057
PubMed:
35844434

GWAS Reveals a Novel Candidate Gene CmoAP2/ERF in Pumpkin (Cucurbita moschata) Involved in Resistance to Powdery Mildew.

Alavilli H et al (2022).
Int J Mol Sci.
DOI:
10.3390/ijms23126524
PubMed:
35742978

Coleoptera claws and trichome interlocking.

Salerno G et al (2022).
J Comp Physiol A Neuroethol Sens Neural Behav Physiol.
DOI:
10.1007/s00359-022-01554-1
PubMed:
35616716

In vivo pharmacokinetic study of a Cucurbita moschata polysaccharide after oral administration.

Li F et al (2022).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2022.01.111
PubMed:
35090937

Pumpkin (Cucurbita moschata) HSP20 Gene Family Identification and Expression Under Heat Stress.

Hu Y et al (2021).
Front Genet.
DOI:
10.3389/fgene.2021.753953
PubMed:
34721541

Effect of dietary pumpkin (Cucurbita moschata) seed meal on layer performance and egg quality characteristics.

Vlaicu PA and Panaite TD (2022).
Anim Biosci.
DOI:
10.5713/ab.21.0044
PubMed:
34293842

Genome-Wide Characterization and Expression Analysis of CAMTA Gene Family Under Salt Stress in Cucurbita moschata and Cucurbita maxima.

Genetics
Yuan J et al (2021).
Front Genet.
DOI:
10.3389/fgene.2021.647339
PubMed:
34220934

Screening of Cucurbita maxima and Cucurbita moschata Genotypes for Resistance Against Meloidogyne arenaria, M. incognita, M. javanica, and M. luci.

Genetics
Aydınlı G, Kurtar ES and Mennan S (2019).
J Nematol.
DOI:
10.21307/jofnem-2019-057
PubMed:
34179793

Morphological and Molecular Identification of Seedborne Fungi in Squash (Cucurbita maxima, Cucurbita moschata).

Moumni M et al (2020).
Plant Dis.
DOI:
10.1094/PDIS-04-19-0741-RE
PubMed:
32223640

Near-infrared spectroscopy in vegetables and humans: An observational study.

Kahn RA and Anyanwu A (2018).
Eur J Anaesthesiol.
DOI:
10.1097/EJA.0000000000000855
PubMed:
30020143

Cucurbita moschata Duch. and its active component, β-carotene effectively promote the immune responses through the activation of splenocytes and macrophages.

Immunology
Kim HY et al (2016).
Immunopharmacol Immunotoxicol.
DOI:
10.1080/08923973.2016.1202960
PubMed:
27315229