Cucurbita pepo

Common Names: cocozelle, field pumpkin, jack-o-lantern pumpkin, vegetable marrow, zucchini

Ethnobotanical Studies

Clinical Trials

Pumpkin seed oil (Cucurbita pepo) versus tamsulosin for benign prostatic hyperplasia symptom relief: a single-blind randomized clinical trial.

Zerafatjou N et al (2021).
BMC Urol.
DOI:
10.1186/s12894-021-00910-8
PubMed:
34666728

Studies

Simultaneous determination of cucurbitacins B, D, and E in Cucurbita seed oils by HPLC-DAD.

Goya-Jorge E, Jorge-Rodríguez ME and Saucedo-Hernández Y (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2394097
PubMed:
39234765

Crosstalk between Ethylene, Jasmonate and ABA in Response to Salt Stress during Germination and Early Plant Growth in Cucurbita pepo.

Alonso S et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25168728
PubMed:
39201415

First report of squash vein yellowing virus naturally infecting cucumber, squash and melon in Jordan.

Hussein A et al (2024).
Plant Dis.
DOI:
10.1094/PDIS-06-24-1264-PDN
PubMed:
39172496

Cucurbit Leaf Crumple Virus (CuLCrV) is Seed Transmitted in Yellow Squash (Cucurbita pepo L.).

Dhadly DK et al (2024).
Plant Dis.
DOI:
10.1094/PDIS-06-24-1330-RE
PubMed:
39151040

Comprehensive metabolomics and chemometrics unravel potential anti-diabetic metabolites of pumpkin (Cucurbita pepo L.) fruits through UPLC-QqQ-MS and GC-MS analyses.

Summary

Scientists analyzed the chemical compounds in different parts of pumpkins and found they can help manage diabetes by inhibiting carbohydrase enzymes and promoting glucose uptake. Pumpkin is a potential functional food for diabetes management.

Diabetes
Abdelmonsef M et al (2024).
Food Res Int.
DOI:
10.1016/j.foodres.2024.114771
PubMed:
39147478

Correction to: A mutation in the brassinosteroid biosynthesis gene CpDWF5 disrupts vegetative and reproductive development and the salt stress response in squash (Cucurbita pepo).

Genetics
(2024).
Hortic Res.
DOI:
10.1093/hr/uhae217
PubMed:
39132642

Map-based cloning reveals Cpgp gene encoding an APRR2 protein to regulate the green fruit peel formation in Cucurbita pepo.

Genetics
Gebretsadik K et al (2024).
Mol Breed.
DOI:
10.1007/s11032-024-01492-7
PubMed:
39130616

Production of set-type probiotic and prebiotic yogurt-like products using Enterococcus faecium and Enterococcus faecalis strains in combination with pumpkin waste.

Kiliç Kanak E and Öztürk Yilmaz S (2024).
Microb Pathog.
DOI:
10.1016/j.micpath.2024.106844
PubMed:
39128644

Negative and sex-specific effects of drought on flower production, resources and pollinator visitation, but not on floral scent in monoecious Cucurbita pepo.

Barman M, Tenhaken R and Dötterl S (2024).
New Phytol.
DOI:
10.1111/nph.20016
PubMed:
39117354

Simulation of early season herbivory via mechanical damage affects flower production in pumpkin (Cucurbita pepo ssp. pepo).

Gray HL et al (2024).
Ann Bot.
DOI:
10.1093/aob/mcae118
PubMed:
39093025

Jasmonate-insensitive mutant jar1b prevents petal elongation and flower opening coupling with parthenocarpic fruit development in Cucurbita pepo.

Gautam K et al (2024).
Plant Physiol Biochem.
DOI:
10.1016/j.plaphy.2024.108923
PubMed:
39002308

Microneedle assisted delivery of the cloned components of cucurbit leaf crumple virus in yellow squash (Cucurbita pepo).

Kavalappara SR et al (2024).
J Virol Methods.
DOI:
10.1016/j.jviromet.2024.114992
PubMed:
38936512

Susceptibility of Yellow Squash and Zucchini Cultivars to the Sweetpotato Whitefly, Bemisia tabaci Gennadius (MEAM1), in the Southeastern United States.

Mbata GN et al (2024).
Insects.
DOI:
10.3390/insects15060429
PubMed:
38921145

The transcription factor CpMYB62 controls the genetic network that leads to the determination of female flowers in Cucurbita pepo.

Segura M et al (2024).
Hortic Res.
DOI:
10.1093/hr/uhae115
PubMed:
38919554

Fine mapping and transcriptome profiling reveal CpAPRR2 to modulate immature fruit rind color formation in zucchini (Cucurbita pepo).

Genetics
Ding W et al (2024).
Theor Appl Genet.
DOI:
10.1007/s00122-024-04676-z
PubMed:
38909110

Development of simplified probabilistic models for predicting phytoextraction timeframes of soil contaminants: demonstration at the DDX-contaminated Kolleberga tree nursery in Sweden.

Drenning P et al (2024).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-024-33858-x
PubMed:
38834929

Temperature and soil moisture manipulation yields evidence of drought-induced pollen limitation in bee-pollinated squash.

Gambel J and Holway DA (2024).
Ecol Evol.
DOI:
10.1002/ece3.11400
PubMed:
38832140

The metabolism of amino acids, AsA and abscisic acid induced by strigolactone participates in chilling tolerance in postharvest zucchini fruit.

Wang L et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2024.1402521
PubMed:
38807778

Inoculation of Native Arbuscular Mycorrhizae and Bacillus subtilis Can Improve Growth in Vegetable Crops.

Gebreslassie S et al (2024).
Int J Microbiol.
DOI:
10.1155/2024/9226715
PubMed:
38745889

Archaeobotanical evidence supports indigenous cucurbit long-term use in the Mesoamerican Neotropics.

Domic AI et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-60723-1
PubMed:
38740801

Dieldrin accumulation, distribution in plant parts and phytoextraction potential for several plant species and Cucurbita pepo varieties.

Affholder MC et al (2024).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2024.172968
PubMed:
38705310

Genome-Wide Identification of the WRKY Gene Family and Functional Characterization of CpWRKY5 in Cucurbita pepo.

Genetics
Chen J et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25084177
PubMed:
38673762

Acaricidal Efficacy of Thirty-Five Egyptian Plants Against the Camel Tick, Hyalomma Dromedarii.

Khater HF et al (2024).
Acta Parasitol.
DOI:
10.1007/s11686-024-00801-6
PubMed:
38671280

Winter rye cover crops shelter competent squash phyllosphere bacteria to reduce Pseudomonas syringae pv. lachrymans growth and angular leaf spot symptoms.

Maglione R et al (2024).
Phytopathology.
DOI:
10.1094/PHYTO-08-22-0291-R
PubMed:
38648089

A mutation in the brassinosteroid biosynthesis gene CpDWF5 disrupts vegetative and reproductive development and the salt stress response in squash (Cucurbita pepo).

Genetics
Alonso S et al (2024).
Hortic Res.
DOI:
10.1093/hr/uhae050
PubMed:
38645681

A novel O-methyltransferase Cp4MP-OMT catalyses the final step in the biosynthesis of the volatile 1,4-dimethoxybenzene in pumpkin (Cucurbita pepo) flowers.

Hoepflinger MC et al (2024).
BMC Plant Biol.
DOI:
10.1186/s12870-024-04955-3
PubMed:
38632532

Embryo growth alteration and oxidative stress responses in germinating Cucurbita pepo seeds exposed to cadmium and copper toxicity.

Immunology
Acila S, Derouiche S and Allioui N (2024).
Sci Rep.
DOI:
10.1038/s41598-024-58635-1
PubMed:
38615032

Breaking boundaries: a novel role for CUC genes in sex determination in cucurbits.

Genetics
Pelayo MA and Wellmer F (2024).
J Exp Bot.
DOI:
10.1093/jxb/erae056
PubMed:
38534185

Effect of different salinity on seed germination, growth parameters and biochemical contents of pumpkin (Cucurbita pepo L.) seeds cultivars.

Irik HA and Bikmaz G (2024).
Sci Rep.
DOI:
10.1038/s41598-024-55325-w
PubMed:
38519514

Morphological Analyses and QTL Mapping of Mottled Leaf in Zucchini (Cucurbita pepo L.).

Wang K et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25052491
PubMed:
38473740

Structural and functional characterization of genes PYL-PP2C-SnRK2s in the ABA signalling pathway of Cucurbita pepo.

Genetics
Iglesias-Moya J et al (2024).
BMC Genomics.
DOI:
10.1186/s12864-024-10158-9
PubMed:
38468207

Preliminary assessment of environmental safety (ecosafety) of dextrin-based nanosponges for environmental applications.

Bellingeri A et al (2024).
Ecotoxicol Environ Saf.
DOI:
10.1016/j.ecoenv.2024.116120
PubMed:
38401200

Evaluation of Antioxidant Effects of Pumpkin (Cucurbita pepo L.) Seed Extract on Aging- and Menopause-Related Diseases Using Saos-2 Cells and Ovariectomized Rats.

Summary

Pumpkin seed extract reduces oxidative stress, inflammation, and weight in menopausal rats by boosting antioxidant and vasculoprotective gene expression. Good for menopausal health.

EndocrinologyImmunology
Oh J et al (2024).
Antioxidants (Basel).
DOI:
10.3390/antiox13020241
PubMed:
38397839

First Report of Root Rot Caused by Fusarium incarnatum on Mongolian Snake gourd in China.

Yan L et al (2024).
Plant Dis.
DOI:
10.1094/PDIS-07-23-1424-PDN
PubMed:
38356278

First report of cucurbit yellow vine disease caused by Serratia marcescens on cucurbit crops in Iowa.

Mphande K, Beattie GA and Gleason ML (2024).
Plant Dis.
DOI:
10.1094/PDIS-12-23-2716-PDN
PubMed:
38332492

Identification of ARF genes in Cucurbita pepo L and analysis of expression patterns, and functional analysis of CpARF22 under drought, salt stress.

Genetics
Zhang MJ et al (2024).
BMC Genomics.
DOI:
10.1186/s12864-024-09992-8
PubMed:
38273235

Ameliorative Potential of Pumpkin Seed Oil (Cucurbita pepo L.) Against Tramadol-Induced Oxidative Stress.

Summary

Tossers studied the toxic effects of tramadol, a pain medication, which is commonly used but lacks regulation. The research aims to understand how to protect against its toxicity.

Immunology
Ekpono EU et al (2024).
Dose Response.
DOI:
10.1177/15593258241226913
PubMed:
38234695

Pumpkin seeds (Cucurbita pepo subsp. ovifera) decoction promotes Trichinella spiralis expulsion during intestinal phase via "Weep and Sweep" mechanism.

Summary

This study tested the impact of pumpkin decoction on Trichinella spiralis in mice. Pumpkin decoction, especially when combined with honey, significantly reduced adult worm count, improved immune response, and decreased histological changes. Pumpkin decoction could be a promising alternative treatment for T. spiralis.

Gastroenterology
Saleh AS et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-51616-4
PubMed:
38233460

Deciphering Multi-target Pharmacological Mechanism of Cucurbita pepo Seeds against Kidney Stones: Network Pharmacology and Molecular Docking Approach.

Shahzadi A et al (2024).
Curr Pharm Des.
DOI:
10.2174/0113816128271781231104151155
PubMed:
38213175

Transcriptome-based analysis of candidate gene markers associated with resistance mechanism to Phytophthora melonis that causes root and crown rot in pumpkin.

Genetics
Najafi M et al (2024).
Funct Plant Biol.
DOI:
10.1071/FP23038
PubMed:
38207292

Scanning electron microscopic exploration of intricate pollen morphology and antimicrobial potentials of gourd family.

Summary

This study analyzes the pollen morphology of Cucurbitaceae plants using scanning electron microscopy (SEM) and identifies their antimicrobial potentials. It provides comprehensive analysis and taxonomic understanding of Cucurbitaceae pollen, showcasing their potential as sources for novel antimicrobial compounds.

Antimicrobial
Alhomaidi E et al (2024).
Microsc Res Tech.
DOI:
10.1002/jemt.24485
PubMed:
38189103

Mainstreaming traditional fruits, vegetables and pulses for nutrition, income, and sustainability in sub-Saharan Africa: the case for Kenya and Ethiopia.

Ngigi PB et al (2023).
Front Nutr.
DOI:
10.3389/fnut.2023.1197703
PubMed:
38146328

Comparative RNA-Seq Analysis between Monoecious and Androecious Plants Reveals Regulatory Mechanisms Controlling Female Flowering in Cucurbita pepo.

Genetics
Segura M et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242417195
PubMed:
38139023

Exploring the Chemical Composition of Female Zucchini Flowers for Their Possible Use as Nutraceutical Ingredient.

Castaldo L et al (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12122108
PubMed:
38136227

A miR164 resistant mutation in the transcription factor gene CpCUC2B enhances carpel arrest and ectopic boundary specification in Cucurbita pepo flower development.

Genetics
Segura M et al (2023).
J Exp Bot.
DOI:
10.1093/jxb/erad486
PubMed:
38066672

Evaluation of the cytotoxicity, antioxidant activity, and molecular docking of biogenic zinc oxide nanoparticles derived from pumpkin seeds.

Immunology
Kadir NHA et al (2023).
Microsc Res Tech.
DOI:
10.1002/jemt.24437
PubMed:
38018343

Anthelmintic potential of sulphonamides and Cucurbita pepo seeds extract on Heterophyes heterophyes experimentally infected mice.

Ashour DS et al (2023).
J Parasit Dis.
DOI:
10.1007/s12639-023-01620-8
PubMed:
38009148

Residue dynamics of a contact and a systemic fungicide in pollen, nectar, and other plant matrices of courgette (Cucurbita pepo L.).

Gierer F et al (2023).
Environ Pollut.
DOI:
10.1016/j.envpol.2023.122931
PubMed:
38006995

Use of Insect Exclusion Row Cover and Reflective Silver Plastic Mulching to Manage Whitefly in Zucchini Production.

Rutz T et al (2023).
Insects.
DOI:
10.3390/insects14110863
PubMed:
37999062

Investigation of the effects of different processing methods on the selected nutritional properties of pumpkin and determining the appropriate process for pumpkin yogurt.

Sıçramaz H and Ayar A (2023).
Food Sci Nutr.
DOI:
10.1002/fsn3.3580
PubMed:
37970424

Further Molecular Diagnosis Determines Lack of Evidence for Real Seed Transmission of Tomato Leaf Curl New Delhi Virus in Cucurbits.

Sáez C et al (2023).
Plants (Basel).
DOI:
10.3390/plants12213773
PubMed:
37960129

Investigation of the effect of Bacillus subtilis and Bacillus thuringiensis as Bio-agents against powdery mildew (Podosphaera xanthii) disease in zucchini (Cucurbita pepo L.).

Ünlü E et al (2023).
Microb Pathog.
DOI:
10.1016/j.micpath.2023.106430
PubMed:
37940063

Endophyte Community Changes in the Seeds of Eight Plant Species following Inoculation with a Multi-Endophytic Bacterial Consortium and an Individual Sphingomonas wittichii Strain Obtained from Noccaea caerulescens.

Langill T et al (2023).
Plants (Basel).
DOI:
10.3390/plants12203660
PubMed:
37896123

A Genome-Wide Identification and Comparative Analysis of the Heavy-Metal-Associated Gene Family in Cucurbitaceae Species and Their Role in Cucurbita pepo under Arsenic Stress.

Genetics
Flores-Iga G et al (2023).
Genes (Basel).
DOI:
10.3390/genes14101877
PubMed:
37895226

Molecular identification and development of an infectious cDNA clone of Trichosanthes kirilowii-infecting cucurbit mild mosaic virus.

Genetics
Chen C et al (2023).
Virology.
DOI:
10.1016/j.virol.2023.109891
PubMed:
37826911

Synthesis of dietary lipids from pumpkin (Cucurbita pepo. L) oil obtained by enzymatic extraction: a sustainable approach.

Atsakou AE et al (2023).
3 Biotech.
DOI:
10.1007/s13205-023-03781-y
PubMed:
37822549

Analyzing genomic variation in cultivated pumpkins and identification of candidate genes controlling seed traits.

Summary

This study analyzed pumpkin breeding materials and identified genetic loci controlling seed traits. It found significant variations and mapped 15 loci associated with pumpkin seed traits, aiding commercial breeding and improving seed traits.

Genetics
Lee CY et al (2023).
Plant Genome.
DOI:
10.1002/tpg2.20393
PubMed:
37776006

Major latex-like proteins show pH dependency in their binding to hydrophobic organic pollutants.

Fujita K et al (2023).
J Pestic Sci.
DOI:
10.1584/jpestics.D23-014
PubMed:
37745171

Green synthesis of zinc and nickel dual-doped cerium oxide nanoparticles: antioxidant activity and cytotoxicity effects.

Summary

Dual-doped cerium oxide nanoparticles (CeO-NPs) were synthesized using zucchini peel extract. They showed increased size at higher temperatures and effectively killed cells at inhibitory concentrations. These nanoparticles also affected the enzymatic activity of SOD and CAT, intensifying CAT activity without affecting SOD activity.

Immunology
Mahmoodi P et al (2023).
Bioprocess Biosyst Eng.
DOI:
10.1007/s00449-023-02920-2
PubMed:
37700115

Ethnobotanical study of nutraceutical plants used to manage opportunistic infections associated with HIV/AIDS in Acholi sub-region, Northern Uganda.

Ethnobotany
Ikinyom N et al (2023).
Trop Med Health.
DOI:
10.1186/s41182-023-00540-w
PubMed:
37658427

QTL mapping and stability analysis of trichome density in zucchini (Cucurbita pepo L.).

Wang Y et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1232154
PubMed:
37636121

Augmentative biological control for squash bug (Hemiptera: Coreidae) using the egg parasitoid, Hadronotus pennsylvanicus (Hymenoptera: Scelionidae).

Boyle SM et al (2023).
Environ Entomol.
DOI:
10.1093/ee/nvad079
PubMed:
37579059

Effect of citric acid on phytoextraction potential of Cucurbita pepo, Lagenaria siceraria, and Raphanus sativus plants exposed to multi-metal stress.

Ibrahim EA et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-40233-2
PubMed:
37567950

First Report of Cucurbit Yellow Vine Disease Caused by Serratia marcescens on Cucurbits in New York.

Rodriguez-Herrera KD et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-06-23-1051-PDN
PubMed:
37486276

First Report of Cucumber Green Mottle Mosaic Virus Infecting Zucchini (Cucurbita pepo) and Wax Gourd (Benincasa hispida) in China.

Sun X et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-05-23-0881-PDN
PubMed:
37467132

Cucurbita pepo contains characteristic proteins without a signal peptide in the xylem sap.

Inui H et al (2023).
J Plant Physiol.
DOI:
10.1016/j.jplph.2023.154038
PubMed:
37413840

Cucurbita pepo seeds improve peripheral neuropathy in diabetic rats by modulating the inflammation and oxidative stress in rats.

Summary

Study investigated the effects of Cucurbita pepo in reducing diabetic neuropathy in rats induced with streptozotocin. Results suggest potential for C. pepo as a treatment option.

DiabetesImmunology
Kaur N et al (2023).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-023-28339-6
PubMed:
37400700

LC-MS Metabolomic Profiling of Five Types of Unrefined, Cold-Pressed Seed Oils to Identify Markers to Determine Oil Authenticity and to Test for Oil Adulteration.

Sumara A et al (2023).
Molecules.
DOI:
10.3390/molecules28124754
PubMed:
37375308

Green synthesis of cerium oxide nanoparticles using zucchini peel extract for cytotoxic and photocatalytic properties.

Mahmoodi P et al (2023).
Bioprocess Biosyst Eng.
DOI:
10.1007/s00449-023-02888-z
PubMed:
37326639

Characterization of rice straw lignin phenolics and evaluation of their role in pollen tube growth in Cucurbita pepo L.

Mankoo RK, Kaur J and Chahal GK (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2225126
PubMed:
37322891

The Effects of Coriandrum sativum L. and Cucurbita pepo L. against Gastrointestinal Parasites in Swine: An In Vivo Study.

Băieş MH et al (2023).
Microorganisms.
DOI:
10.3390/microorganisms11051230
PubMed:
37317204

First Report of Cucurbita Blossom Blight and Fruit Rot Caused by Choanephora cucurbitarum in Mexico.

Garcia-Estrada RS et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-04-23-0748-PDN
PubMed:
37311232

Lessons learned from metabolic engineering in hairy roots: Transcriptome and metabolic profile changes caused by Rhizobium-mediated plant transformation in Cucurbitaceae species.

Genetics
Almeida A et al (2023).
Plant Physiol Biochem.
DOI:
10.1016/j.plaphy.2023.107797
PubMed:
37302255

Divergent responses of generalist and specialist pollinators to experimental drought: Outcomes for plant reproduction.

Gambel J and Holway DA (2023).
Ecology.
DOI:
10.1002/ecy.4111
PubMed:
37243967

First report of Watermelon Crinkle Leaf-Associated Virus (WCLaV) -1 and WCLaV-2 infecting straightneck squash in the United States.

Jailani AAK, Iriarte FB and Paret ML (2023).
Plant Dis.
DOI:
10.1094/PDIS-01-23-0079-PDN
PubMed:
37102729

Combined Chemical and Ecotoxicological Measurements for River Sediment Management in an On-Land Deposit Scenario.

Bedell JP et al (2023).
Arch Environ Contam Toxicol.
DOI:
10.1007/s00244-023-00997-0
PubMed:
37097447

First report of tomato leaf curl New Delhi virus infecting several cucurbit plants in China.

Gu Q et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-01-23-0180-PDN
PubMed:
37081636

The expansion of agriculture has shaped the recent evolutionary history of a specialized squash pollinator.

Pope NS et al (2023).
Proc Natl Acad Sci U S A.
DOI:
10.1073/pnas.2208116120
PubMed:
37011184

Genome-wide identification of NHX (Na(+)/H(+) antiporter) gene family in Cucurbita L. and functional analysis of CmoNHX1 under salt stress.

Genetics
Shen C et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1136810
PubMed:
36998676

Characterization of the USDA Cucurbita pepo, C. moschata, and C. maxima germplasm collections.

Hernandez CO et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1130814
PubMed:
36993863

Small RNA Profiling of Cucurbit Yellow Stunting Disorder Virus from Susceptible and Tolerant Squash (Cucurbita pepo) Lines.

Genetics
Kavalappara SR et al (2023).
Viruses.
DOI:
10.3390/v15030788
PubMed:
36992495

Fungicide Dissipation Kinetics and Dietary Exposure Risk Assessment in Squash Fruit and Leaf.

An D et al (2023).
Foods.
DOI:
10.3390/foods12061291
PubMed:
36981217

Interspecific hybridization for transfer of hull-less seed trait from Cucurbita pepo to C. moschata.

Kaur B et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-29935-9
PubMed:
36944656

In Vivo Antiphytoviral and Aphid Repellency Activity of Essential Oils and Hydrosols from Mentha suaveolens and Foeniculum vulgare to Control Zucchini Yellow Mosaic Virus and Its Vector Aphis gossypii.

Phytochemistry
Taglienti A et al (2023).
Plants (Basel).
DOI:
10.3390/plants12051078
PubMed:
36903936

Role of Phytotherapy in the Management of BPH: A Summary of the Literature.

Review
Antoniou V et al (2023).
J Clin Med.
DOI:
10.3390/jcm12051899
PubMed:
36902686

Effect of Thermal Pretreatment on the Physiochemical Properties and Stability of Pumpkin Seed Milk.

Yu M et al (2023).
Foods.
DOI:
10.3390/foods12051056
PubMed:
36900573

The In Vitro Anticoccidial Activity of Some Herbal Extracts against Eimeria spp. Oocysts Isolated from Piglets.

Bǎieş MH et al (2023).
Pathogens.
DOI:
10.3390/pathogens12020258
PubMed:
36839530

Physiological and Transcriptomic Analyses Revealed That Humic Acids Improve Low-Temperature Stress Tolerance in Zucchini (Cucurbita pepo L.) Seedlings.

Li H et al (2023).
Plants (Basel).
DOI:
10.3390/plants12030548
PubMed:
36771631

The ethylene receptor mutation etr2b reveals crosstalk between ethylene and ABA in the control of Cucurbita pepo germination.

Iglesias-Moya J et al (2023).
Physiol Plant.
DOI:
10.1111/ppl.13864
PubMed:
36718078

Molecular characterization of a novel gammacarmovirus infecting cucurbits in India.

Neeraganti DK et al (2023).
Arch Virol.
DOI:
10.1007/s00705-022-05643-z
PubMed:
36653663

A New Benzothiadiazole Derivative with Systemic Acquired Resistance Activity in the Protection of Zucchini (Cucurbita pepo convar. giromontiina) against Viral and Fungal Pathogens.

Spychalski M et al (2022).
Plants (Basel).
DOI:
10.3390/plants12010043
PubMed:
36616170

Effect of Leaf Trichomes in Different Species of Cucurbitaceae on Attachment Ability of the Melon Ladybird Beetle Chnootriba elaterii.

Saitta V et al (2022).
Insects.
DOI:
10.3390/insects13121123
PubMed:
36555032

Tendril Anatomy: A Tool for Correct Identification among Cucurbitaceous Taxa.

Abbas N et al (2022).
Plants (Basel).
DOI:
10.3390/plants11233273
PubMed:
36501313

Jasmonate-deficient mutant lox3a reveals crosstalk between JA and ET in the differential regulation of male and female flower opening and early fruit development in Cucurbita pepo.

Cebrián G et al (2022).
J Exp Bot.
DOI:
10.1093/jxb/erac468
PubMed:
36453889

Inter and intraspecific variability of dieldrin accumulation in Cucurbita fruits: New perspectives for food safety and phytomanagement of contaminated soils.

Affholder MC et al (2023).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2022.160152
PubMed:
36395833

Interactions of airborne graphene oxides with the sexual reproduction of a model plant: When production impurities matter.

Zanelli D et al (2023).
Chemosphere.
DOI:
10.1016/j.chemosphere.2022.137138
PubMed:
36343732

Correction: Extract from Cucurbita pepo improves BPH symptoms without affecting sexual function: a 24-month noninterventional study.

Theil G et al (2022).
World J Urol.
DOI:
10.1007/s00345-022-04132-x
PubMed:
36056928

Transcriptomic Analysis Reveal the Molecular Mechanisms of Seed Coat Development in Cucurbita pepo L.

Xue Y et al (2022).
Front Plant Sci.
DOI:
10.3389/fpls.2022.772685
PubMed:
35283914

Impact of microplastics on growth, photosynthesis and essential elements in Cucurbita pepo L.

Colzi I et al (2022).
J Hazard Mater.
DOI:
10.1016/j.jhazmat.2021.127238
PubMed:
34844356

Antiparkinsonian activity of Cucurbita pepo seeds along with possible underlying mechanism.

Summary

Researchers in Pakistan investigated the potential anti-Parkinson's activity of a methanolic extract of Cucurbita pepo (MECP) seeds. Using a rat model, they found that the extract improved motor functions. They also noted dose-dependent increases in catalase, superoxide dismutase, and glutathione levels, as well as decreases in malondialdehyde and nitrite levels. Molecular docking simulation suggested that certain phytoconstituents could bind to the active site of acetylcholine-esterase (AchE), a protein involved in the disease. Additionally, gene expression analysis revealed upregulation of alpha-synuclein and downregulation of TNF-alpha and IL-1beta. Finally, ADMET analysis predicted that selected phytochemicals exhibited moderately acceptable pharmacokinetics and toxicity. Overall, the results suggest that MECP could potentially ameliorate Parkinson's symptoms and may be a lead remedy for treatment.

Neuroscience
Saleem U et al (2021).
Metab Brain Dis.
DOI:
10.1007/s11011-021-00707-6
PubMed:
33759084

Tracing back the origin of pumpkins (Cucurbita pepo ssp. pepo L.) in Mexico.

Castellanos-Morales G et al (2019).
Proc Biol Sci.
DOI:
10.1098/rspb.2019.1440
PubMed:
31409251

The role of Cucurbita pepo in the management of patients affected by lower urinary tract symptoms due to benign prostatic hyperplasia: A narrative review.

Review
Damiano R et al (2016).
Arch Ital Urol Androl.
DOI:
10.4081/aiua.2016.2.136
PubMed:
27377091