Common Names: common turmeric, turmeric
Uses: Detoxifying agent (he'a); Vaginal and urethral discharge; COVID-19; Eczema; Skin disorders (he'a); Cough; Detoxifying agent (pu'a roto); Effects of reduced temperature; Flu; Heat rash; Lower abdominal disorders; Menstrual cycle bleeding disorders; Restlessness, irritability, jerk; Stomachache; Urinary incontinence; Urinary tract infection; Vaginal prurit; Wound, cut, burn
Researchers found FITOPROT + PBM reduced OM in head neck cancer patients undergoing RT. It also decreased inflammatory cytokines. Consider using this combo for OM prevention in similar patients.
Traditional Thai medicine Ya-Samarn-Phlae (YaSP) used for wounds, particularly diabetic foot ulcers. Study validates clinical use, identifies chemical markers, and evaluates wound healing properties. Important for evidence-based medicine and development of new treatments.
Scientists analyzed research trends on antioxidants, herbs, and natural compounds for obesity and NAFLD. China, Korea, and USA are main contributors. Key compounds include resveratrol, curcumin, and quercetin. Study provides valuable insights for future research on obesity and NAFLD treatments.
Researchers studied the impact of curcumin on the STAT3 signaling pathway in breast cancer, showing potential for innovative treatment strategies. Crucial for ongoing research to improve BC outcomes.
Researchers found that combining curcumin and near-infrared radiation in photodynamic therapy effectively reduces cell proliferation in glioblastoma cells, without harming healthy cells. This promising approach may lead to improved treatment outcomes for this aggressive brain cancer.
Researchers synthesized hybrid organic-inorganic complexes of copper and cobalt to enhance the bioavailability and solubility of curcumin, a potent natural chemical with anti-inflammatory, antimicrobial, antioxidant, and anticancer properties. This study evaluates their antimicrobial potential against various pathogens.
Researchers studied the role of oxidative stress and acute phase response in coccidiosis in various animals. Dietary additives like Curcuma longa can reduce oxidative damage and improve antioxidant levels. More research is needed for other animal species.
Researchers studied the antiobesity effects of fermented and unfermented turmeric on obese mice. Fermented turmeric showed greater weight loss, improved metabolic parameters, and modulation of gut microbiota, suggesting it may be a promising antiobesity agent.
Curcumin, a compound in turmeric, shows promise as a potent anticancer agent. Nanospheres provide an effective delivery method for curcumin, improving targeting and efficacy in cancer treatment, with minimal side effects.
Folate-modified curcumin nanoparticles show promise in targeting cancer cells with higher efficacy and lower toxicity, based on preclinical studies. Clinical trials needed for confirmation.
Curcumin, a bioactive phytochemical found in turmeric, shows promise in combating age-related neurological diseases due to its antioxidant and anti-inflammatory properties. Consuming curcumin may help prevent cognitive decline and memory disorders in the elderly.
Review explores multifaceted pathophysiology of Alzheimer's disease, including cholinergic, tau protein, Aβ, oxidative stress, and metal ion hypotheses. Herbal interventions show potential for neuroprotection, but face limitations. DHA and Nicotine also show promise. Future research needed.
Researchers identified Cannabis sativa L. as a potent inhibitor of MRSA, with cannabidiol and Δ9-THC showing bactericidal action. This plant-based alternative may help combat antimicrobial resistance in bovine biofilm-associated MRSA infections.
Researchers studied medicinal plants used by indigenous communities in Bangladesh for helminth infections. Discovering phytochemicals with anthelmintic activity could lead to new drugs to combat drug-resistant helminthiases in underdeveloped regions.
Study finds potential benefits of medicinal plants like Curcuma longa, Syzygium aromaticum, and Zingiber officinale in treating rheumatoid arthritis due to antioxidant and anti-inflammatory properties, offering safer alternative to conventional treatments.
Turmeric regulates gut-liver axis to treat hepatobiliary diseases. Safe, effective, with potential clinical benefits. More research needed for clinical application.
TL;DR: Curcumin from turmeric has anti-inflammatory, antioxidant, and potential anticancer effects by interacting with key proteins. Promising for cancer and inflammatory diseases, with growing therapeutic applications.
This study shows that a TCM formula containing AACO has potential benefits for treating chronic heart failure. Consider integrating into lab protocols for further investigation.
Nanoemulsions containing curcumin showed stable characteristics and antibacterial effects against resistant bacteria, enhancing ceftazidime activity and inhibiting biofilm formation. Promising for future clinical trials against multidrug-resistant Klebsiella pneumoniae infections.
Study investigated natural product curcumin's effectiveness in treating Alzheimer's disease. Curcumin has anti-amyloid & anti-inflammatory properties, but poor bioavailability. Novel formulations improve bioavailability, potential treatment option for AD.
Researchers investigated the neuroprotective effects of a formulation containing Bacopa monnieri leaves, Nigella sativa, and Curcuma longa rhizome seeds. This formulation may help protect against oxidative stress and cell death induced by diclofenac, a common anti-inflammatory drug.
Curcumin in turmeric helps reduce oxidative stress, inflammation, and gut issues in chronic kidney disease (CKD) patients. This study examines curcumin's effects on CKD patients undergoing peritoneal dialysis, focusing on oxidative stress, inflammation markers, and toxins from gut bacteria.
This study investigates the anticancer activity of Curcuma aeruginosa essential oil and its nano-formulations. Curcuma aeruginosa has potential in treating diseases and has various properties such as anti-HIV, hepatoprotective, antimicrobial, and anti-androgenic activities. Understanding its anticancer activity could have implications for cancer treatment.
Curcumin, a component of Curcuma longa, shows promise in treating cardiovascular diseases (CVDs) due to its ability to increase nitric oxide (NO) synthesis and impact NO signaling pathways, improving endothelial function and offering anti-inflammatory and antioxidant benefits.
Researchers tested the efficacy of three feed supplements containing different additives (probiotics, turmeric, and fenugreek) on bird health and found that the supplement with fenugreek was the most effective. Further research is needed to explore combinations of these substances and optimal dosages.
Curcumin (CCM) reduces inflammation, cell apoptosis, and oxidative stress caused by intestinal ischemia/reperfusion (I/R) injury. It mediates these effects by inhibiting the Wnt/β-catenin signaling pathway through NKD2 methylation. Promising treatment for I/R injury.
Review explores the pathophysiology of diabetic retinopathy (DR) and the potential of curcumin and β-glucogallin, compounds found in natural sources, to treat and prevent DR. These compounds have shown various health benefits in animal experiments and have been used in traditional herbal medicine.
Researchers studied the potential benefits of turmeric in treating digestive disorders. They found that one of its compounds, curcumin, has anti-inflammatory properties that can help with inflammatory bowel disease.
Curcumin reduces inflammatory markers and affects cellular metabolism in human articular chondrocytes. It targets key proteins involved in pathways related to glycine, serine, and threonine metabolism, pyruvate production, and glycolysis to alleviate osteoarthritis.
Curcumin, found in turmeric, reduces gastric cancer cell growth, migration, and invasion. It suppresses the PI3K signaling pathway, making it a potential therapeutic agent for gastric cancer. Further research is needed for in vivo effectiveness.
This study evaluated the antioxidant and protective properties of certain medicinal plants against oxidative stress in the brain and liver. , , and showed strong effects and could potentially help manage or prevent degenerative diseases.
Combining Nisha and Amalaki can potentially prevent the progression from prediabetes to diabetes. You should care because it offers a natural and effective treatment option for early-stage diabetes.
Curcumin from turmeric has various medicinal qualities and shows anti-cancer properties by impacting biological pathways involved in cancer. Turmimax® has potential as an anti-cancer agent against cervical adenocarcinomas and other cancer types, inducing apoptosis and cell cycle arrest.
This study investigates the potential of native Saudi Arabian plants for treating obesity by identifying phytochemicals that regulate metabolism and reduce fat accumulation, offering natural solutions for obesity treatment.
Scientists studied the impact of herbal medicines on stroke management. Current therapies have limited effectiveness, but herbal medicines could improve outcomes by modulating neuroplasticity. This research addresses the need for novel strategies for stroke treatment.
The study formed a complex of curcumin with Sulfobutyl ether-β-cyclodextrin (SBEβCD) to improve its solubility and bioavailability. The complex showed antimicrobial activity against Escherichia coli and Staphylococcus aureus, suggesting it could be a potential alternative treatment for urinary tract infections.
Various bioactive metabolites found in herbs such as Rosmarinus officinalis and Punica granatum have shown impressive angiotensin converting enzyme (ACE) inhibitory activity. These natural ACE inhibitors could be a potential treatment for hypertension, respiratory distress syndrome, and chronic kidney diseases, but more clinical trials are needed.
Curcuminoids in turmeric boost immunity and help prevent cancer and neurological disorders in humans. They also protect the turmeric plant from salinity stress. Care because they have potential health benefits and plant protection properties.
Encapsulating Curcuma longa oil in chitosan nanopolymer enhances its antibacterial and antifungal effectiveness, inhibiting the growth of harmful bacteria and fungi. This research suggests that encapsulated CLEO could be a promising food preservative, improving its antimicrobial properties.
This study developed a new method using high-performance thin-layer chromatography (HPTLC) to analyze curcumin in different Curcuma species. The results showed different curcumin content between extraction methods and recommended HPTLC for routine quality testing.
This study evaluated the effectiveness of a herbal medicine combined with photobiomodulation therapy and an oral care program in treating radiotherapy-induced oral mucositis and improving patients' quality of life.
Curcuminoids derived from turmeric have shown potential in inhibiting cancer progression and modulating signal transduction pathways, miRNA expression, and biomarkers. Strategies for enhancing bioavailability are explored.
This study used microbiological techniques to identify fungal populations on a deteriorating artwork by Rembrandt. They tested eco-friendly antifungal agents, which effectively inhibited fungal growth. The study offers a nondestructive technique for controlling fungal growth on artworks.
Curcumin, derived from the rhizome, has multiple beneficial effects. It can be made into nanocurcumin for better properties like solubility, stability, and bioavailability.
Curcuma longa (turmeric) was used to synthesize environmentally friendly and economical cobalt oxide nanoparticles. These nanoparticles showed antioxidant, antimicrobial, bioremediation, and anticancer properties.
This study reviewed evidence on turmeric and its compounds' effects on diabetes and metabolic parameters. Findings can help inform treatment decisions for patients with type 2 diabetes, prediabetes, and metabolic syndrome.
Researchers reviewed 21 studies on herbal compounds for liver metastasis inhibition, finding Euphorbia kansui's potential in altering the tumor and liver microenvironments. This could guide future drug development against liver metastasis.
Review finds that plant-based drugs, particularly herbs, used as add-on therapy for COVID-19 show efficacy and safety, potentially enhancing the immune system for treating the virus. (37 words)
Study examines therapeutic potential of antioxidant, anti-inflammatory, immune-stimulating plants against SARS-CoV-2. India leads research, proposes herbal blend for COVID-19 treatment and prevention.
Curcumin, extracted from turmeric, has long been used in traditional medicine for its medicinal properties. A protein called SVCT2, responsible for transporting Vitamin C into cells, is involved in tumor progression and metastasis. However, the impact of curcumin on SVCT2 remains unknown. In our study, we found that curcumin reduced the expression of SVCT2 in cancer cells with wild-type p53. This resulted in decreased cancer cell growth and migration, as well as reduced MMP2 activity. Our findings provide new insights into curcumin's anticancer effects and offer potential therapeutic strategies for treating metastatic migration.
TamaFlex, a herbal supplement, reduces knee joint pain and improves musculoskeletal functions in healthy and osteoarthritis subjects. This study investigates its molecular basis in rat models with induced OA.
In a study on TBI, researchers found that curcumin reduced neuroinflammation, oxidative stress, and neuronal apoptosis in rats. The study demonstrated the effectiveness of curcumin in treating brain injury and suggests it may have therapeutic potential for other neurodegenerative diseases.
A study evaluated the effects of a combination of curcumin and Ginkgo biloba extract on Alzheimer's disease (AD). Results showed that the combination achieved higher levels of curcumin in the brain and plasma, compared to curcumin alone. The combination treatment reversed cognitive impairment induced by AD in rats, with a more pronounced effect on inhibiting various neurological markers and pro-inflammatory cytokines. The combination therapy might be an alternative therapy in the management/prevention of neurological disorders, and future research should focus on synergic effects of herbal drugs.
Curcumin, a natural compound found in turmeric, was investigated for its potential to reduce opioid dependence in rats. The study used immunofluorescence staining and ELISA methods to evaluate cytokine levels, and western blotting to evaluate the expression of μ-opioid receptors. Results showed that curcumin administration significantly attenuated the symptoms of morphine withdrawal syndrome and reduced cytokine levels and inflammation in the prefrontal cortex. Additionally, the expression of μ-opioid receptors was reduced by curcumin. This study highlights the potential of curcumin as a treatment for opioid dependence by targeting neuroinflammation.
Researchers developed a stable, water-soluble form of curcumin, called CDC, which effectively reduces lung injury and inflammation in mice following bacterial exposure. Recently, CDC was found to reduce gene and protein expression of key factors involved in COVID-19 pathogenesis. This review considers the potential of curcumin in treating COVID-19 and bacterial/viral-induced acute respiratory distress syndrome (ARDS) through modulating inflammation.
Curcumin, a compound found in turmeric, has been shown to have neuroprotective properties against neurological disorders. In this study, researchers induced seizures in rats and administered curcumin orally for 17 days. They found that curcumin reduced the number of seizures and protected the rats from brain damage caused by seizures. While curcumin did not prevent seizures or mortality, it attenuated the signs of neuronal damage and inflammation in surviving rats. These results suggest that curcumin may have adaptogen-like effects against brain damage caused by seizures.
Curcumin, found in turmeric, improves symptoms and inflammation in arthritis patients according to recent randomized controlled trials. Relevant for lab decisions.
Scientists are exploring the use of phytochemicals from medicinal plants as potential therapies against SARS CoV-2 and other coronaviruses. They created a library of 110 phytochemicals from different plants and found that ashwagandha and shatavari contained steroidal saponins and alkaloids that could potentially inhibit the virus's hemagglutinin-acetylesterase (HE) glycoprotein receptor. Molecular docking and dynamics simulations suggest that these phytochemicals could mask the active site of the receptor, preventing viral entry into host cells. This approach has potential for developing therapies against future deadly coronaviruses.
Researchers evaluated the effectiveness and safety of Curcuma longa extract and curcumin supplements for osteoarthritis. Findings can inform treatment decisions for the condition.