Cuscuta chinensis

Ethnobotanical Studies

Studies

Parasitism by Cuscuta chinensis is associated with changes in leaf functional traits and hyperspectral characteristics of Eunymus japonicas.

Zhu J et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2024.1372529
PubMed:
39119505

Atractylodes macrocephala Koidz. and Cuscuta chinensis Lam. extract relieves insulin resistance via PI3K/Akt signalling in diabetic Drosophila.

Summary

Researchers studied the effect of AMK-CCL extract on insulin resistance in a diabetic fly model. Results suggest potential for treating T2DM. Further research warranted.

Diabetes
Li Y et al (2024).
J Tradit Complement Med.
DOI:
10.1016/j.jtcme.2024.01.010
PubMed:
39035690

Exploring the Wound Healing Potential of a Cuscuta chinensis Extract-Loaded Nanoemulsion-Based Gel.

Nitthikan N et al (2024).
Pharmaceutics.
DOI:
10.3390/pharmaceutics16050573
PubMed:
38794235

Research in revealing the effects on Cuscuta chinensis to diarrhea type irritable bowel syndrome based on network pharmacology and molecular docking potential mechanism.

Yang S et al (2024).
Medicine (Baltimore).
DOI:
10.1097/MD.0000000000038113
PubMed:
38728495

Cuscuta chinensis flavonoids alleviate ovarian damage in offspring female mice induced by BPA exposure during pregnancy by regulating the central carbon metabolism pathway.

Summary

Pregnant mice exposed to BPA can have reproductive damage in female offspring. CCFs mitigate this damage by regulating central carbon metabolism pathways and reducing oxidative stress. This study informs on potential BPA reproductive damage treatments.

EndocrinologyPhytochemistry
Zhao Q et al (2024).
Ecotoxicol Environ Saf.
DOI:
10.1016/j.ecoenv.2024.116253
PubMed:
38537475

Cuscuta chinensis Lam. Flavonoids (CCLF) alleviate the symptoms of sepsis-associated encephalopathy via PI3K/Nrf2 pathway.

Phytochemistry
Boxiang Q, Liping S and Tong Q (2024).
Behav Brain Res.
DOI:
10.1016/j.bbr.2024.114887
PubMed:
38499156

Neuroprotective effect of the traditional decoction Tian-Si-Yin against Alzheimer's disease via suppression of neuroinflammation.

Summary

Researchers investigated the therapeutic potential of the herbal decoction Tian-Si-Yin for Alzheimer's disease (AD). Tian-Si-Yin, a traditional Chinese medicine, has been used for dementia and neurological conditions. Its effectiveness for AD and its mechanisms are not yet fully understood.

Neuroscience
Zhou L et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117569
PubMed:
38086513

Involvement of estrogen receptor activation in kaempferol-3-O-glucoside's protection against aging-related cognition impairment and microglial inflammation.

Summary

Kaempferol-3-O-glucoside (K-3-G), a flavonoid in Cuscuta Chinensis Lam., improved cognition and reduced inflammation in aging mice. It activated estrogen receptors (ERs) and inhibited microglial inflammation through ERs, suggesting it could be a therapeutic agent for cognitive decline.

EndocrinologyImmunologyNeuroscience
Liu H et al (2023).
Exp Cell Res.
DOI:
10.1016/j.yexcr.2023.113849
PubMed:
37926343

Astragalin: a food-origin flavonoid with therapeutic effect for multiple diseases.

Summary

This article reviews the natural source, pharmacokinetics, and pharmacological activities of astragalin (AG), a natural flavonoid found in various edible plants. AG has therapeutic effects against several diseases, making it a potential functional food for disease therapy.

Review Phytochemistry
Chen J et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1265960
PubMed:
37920216

Herbal therapeutics for female infertility: A systematic review and meta-analysis: Herbal medicine for female infertility.

Review
Hyun JY, Jung HS and Park JY (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117258
PubMed:
37778518

Guben Xiezhuo decoction inhibits M1 polarization through the Raf1/p-Elk1 signaling axis to attenuate renal interstitial fibrosis.

Liu Y et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117189
PubMed:
37716490

Molecular mechanism of Cuscutae semen-radix rehmanniae praeparata in relieving reproductive injury of male rats induced with tripterygium wilfordii multiglycosides: A tandem mass tag-based proteomics analysis.

Phytochemistry
Han S et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1050907
PubMed:
36874004

An RNA-seq transcriptome analysis for investigating the anti-lung cancer activity of medicinal Cuscuta chinensis Lam plant.

CancerGenetics
Maimaiti A, Xu J and Shi L (2022).
Br J Nutr.
DOI:
10.1017/S0007114522003865
PubMed:
36468438

Identification of a Hydroxygallic Acid Derivative, Zingibroside R1 and a Sterol Lipid as Potential Active Ingredients of Cuscuta chinensis Extract That Has Neuroprotective and Antioxidant Effects in Aged Caenorhabditis elegans.

Summary

Researchers studied the effects of two traditional Chinese medicine plants, and found that both extracts improved short-term memory, mechanosensory response, and resistance to oxidative stress in a model organism. Chemical analyses showed the presence of bioactive compounds, including zingibroside R1, which was responsible for the observed health benefits of . A hydroxygallic acid derivative and sterol lipid were also present in the most bioactive fraction of , but hardly in . These findings suggest that has overall anti-aging effects on the model organism and provide insight into the specific components responsible.

ImmunologyNeuroscience
Sayed SMA et al (2022).
Nutrients.
DOI:
10.3390/nu14194199
PubMed:
36235851

Dodder-transmitted mobile systemic signals activate a salt-stress response characterized by a transcriptome change in Citrus sinensis.

Genetics
Duan S et al (2022).
Front Plant Sci.
DOI:
10.3389/fpls.2022.986365
PubMed:
36046588

The Effects of Lycium chinense, Cuscuta chinensis, Senna tora, Ophiopogon japonicus, and Dendrobium nobile Decoction on a Dry Eye Mouse Model.

Yang CC et al (2022).
Medicina (Kaunas).
DOI:
10.3390/medicina58081134
PubMed:
36013601

Molecular Processes of Dodder Haustorium Formation on Host Plant under Low Red/Far Red (R/FR) Irradiation.

Pan H et al (2022).
Int J Mol Sci.
DOI:
10.3390/ijms23147528
PubMed:
35886875

Cuscuta chinensis Lam. Protects Against Light-Induced Retinal Degeneration: Therapeutic Implications for Photoreceptor Degenerative Disorders.

Wu H et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.904849
PubMed:
35754507

A multi-dimensional liquid chromatography/high-resolution mass spectrometry approach combined with computational data processing for the comprehensive characterization of the multicomponents from Cuscuta chinensis.

Phytochemistry
Wang M et al (2022).
J Chromatogr A.
DOI:
10.1016/j.chroma.2022.463162
PubMed:
35635871

Hyperoside: A review on its sources, biological activities, and molecular mechanisms.

Review
Wang Q et al (2022).
Phytother Res.
DOI:
10.1002/ptr.7478
PubMed:
35561084

Study on Active Components of Cuscuta chinensis Promoting Neural Stem Cells Proliferation: Bioassay-Guided Fractionation.

Wang H et al (2021).
Molecules.
DOI:
10.3390/molecules26216634
PubMed:
34771043

Predicting the potential distribution of the parasitic Cuscuta chinensis under global warming.

Ren Z et al (2020).
BMC Ecol.
DOI:
10.1186/s12898-020-00295-6
PubMed:
32386506

Therapeutic Anabolic and Anticatabolic Benefits of Natural Chinese Medicines for the Treatment of Osteoporosis.

Review Arthritis
He J et al (2019).
Front Pharmacol.
DOI:
10.3389/fphar.2019.01344
PubMed:
31824310

Antagonistic Effect of Cuscuta chinensis on a Rat Model with Unilateral Cryptorchidism.

Qin D et al (2019).
Med Sci Monit.
DOI:
10.12659/MSM.916893
PubMed:
31493333

Cuscuta chinensis and C. campestris Attenuate Scopolamine-Induced Memory Deficit and Oxidative Damage in Mice.

Lin MK et al (2018).
Molecules.
DOI:
10.3390/molecules23123060
PubMed:
30467292

Selected hepatoprotective herbal medicines: Evidence from ethnomedicinal applications, animal models, and possible mechanism of actions.

Review Ethnobotany
Ali M et al (2018).
Phytother Res.
DOI:
10.1002/ptr.5957
PubMed:
29047177

Cuscuta chinensis Lam.: A systematic review on ethnopharmacology, phytochemistry and pharmacology of an important traditional herbal medicine.

Review Phytochemistry
Donnapee S et al (2014).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2014.09.032
PubMed:
25281912

Differentiation of Cuscuta chinensis and Cuscuta australis by HPLC-DAD-MS analysis and HPLC-UV quantitation.

He X et al (2011).
Planta Med.
DOI:
10.1055/s-0030-1271186
PubMed:
21674437