Dioscorea deltoidea

Ethnobotanical Studies

Studies

An overview on pharmacological significance, phytochemical potential, traditional importance and conservation strategies of Dioscorea deltoidea: A high valued endangered medicinal plant.

Summary

The endangered Wall. ex Griseb. plant from the Dioscoreaceae family is rich in nutrients and bioactive chemicals with potential therapeutic benefits for inflammatory conditions, cardiovascular diseases, immune deficiencies, and more. Its medicinal properties and use in hormone synthesis make it valuable for medicine and commerce.

Review Phytochemistry
Naseem N et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e31245
PubMed:
38826718

Ethnomedicinal Plants and Herbal Preparations Used by Rural Communities in Tehsil Hajira (Poonch District of Azad Kashmir, Pakistan).

Ethnobotany
Jabeen T et al (2024).
Plants (Basel).
DOI:
10.3390/plants13101379
PubMed:
38794449

Bioreactor Systems for Plant Cell Cultivation at the Institute of Plant Physiology of the Russian Academy of Sciences: 50 Years of Technology Evolution from Laboratory to Industrial Implications.

Review
Titova M, Popova E and Nosov A (2024).
Plants (Basel).
DOI:
10.3390/plants13030430
PubMed:
38337964

Synthesis, antioxidant, antiproliferative activity, molecular docking and DFT studies of novel isoxazole derivatives of diosgenin, a steroidal sapogenin from Dioscorea deltoidea.

Summary

Diosgenin derivatives were synthesized and tested for antioxidant and anticancer activity against breast cancer cell lines. Two compounds showed high efficacy, suggesting potential drug candidates.

CancerImmunology
Yatoo GN and Banday JA (2023).
Fitoterapia.
DOI:
10.1016/j.fitote.2023.105621
PubMed:
37524127

The Hypoglycemic and Hypocholesterolemic Activity of Dioscorea deltoidea, Tribulus terrestris and Panax japonicus Cell Culture Biomass in Rats with High-Fat Diet-Induced Obesity.

Summary

This study found that the suspension cell biomass of certain medicinal plant species can reduce weight gain, fat mass, and improve glucose and cholesterol levels in obese rats. It shows potential for safe and effective natural remedies for obesity.

DiabetesObesity
Povydysh MN et al (2023).
Nutrients.
DOI:
10.3390/nu15030656
PubMed:
36771371

Effect of Phytopreparations Based on Bioreactor-Grown Cell Biomass of Dioscorea deltoidea, Tribulus terrestris and Panax japonicus on Carbohydrate and Lipid Metabolism in Type 2 Diabetes Mellitus.

Diabetes
Povydysh MN et al (2021).
Nutrients.
DOI:
10.3390/nu13113811
PubMed:
34836067

Optimization of diosgenin extraction from Dioscorea deltoidea tubers using response surface methodology and artificial neural network modelling.

Nazir R et al (2021).
PLoS One.
DOI:
10.1371/journal.pone.0253617
PubMed:
34288904

Dioscorea deltoidea Leaf Extract (DDLE) Targets PI3K/AKT/mTOR Pathway and Inhibits Ovarian Cancer Cell Growth.

Cancer
Jiao Y et al (2021).
Dokl Biochem Biophys.
DOI:
10.1134/S1607672921020058
PubMed:
33895931

Antihypoxic Action of Panax Japonicus, Tribulus Terrestris and Dioscorea Deltoidea Cell Cultures: In Silico and Animal Studies.

Lagunin A et al (2020).
Mol Inform.
DOI:
10.1002/minf.202000093
PubMed:
32662208

Studies to Elucidate the Effects of Furostanol Glycosides from Dioscorea deltoidea Cell Culture in a Rat Model of Endothelial Dysfunction.

Phytochemistry
Korokin M et al (2019).
Molecules.
DOI:
10.3390/molecules25010169
PubMed:
31906178

[Formation of protodioscin and deltoside isomers in suspension cultures of Nepal yam (Dioscorea deltoidea Wall.) cells].

Khandy MT et al (2016).
Prikl Biokhim Mikrobiol.
PubMed:
29513486

LC-MS determination of steroidal glycosides from Dioscorea deltoidea Wall cell suspension culture: Optimization of pre-LC-MS procedure parameters by Latin Square design.

Phytochemistry
Sarvin B et al (2018).
J Chromatogr B Analyt Technol Biomed Life Sci.
DOI:
10.1016/j.jchromb.2018.02.012
PubMed:
29477069

Synthesis and biological evaluation of novel 3-O-tethered triazoles of diosgenin as potent antiproliferative agents.

Cancer
Masood-Ur-Rahman et al (2017).
Steroids.
DOI:
10.1016/j.steroids.2016.11.003
PubMed:
27864018

Improved diosgenin production in Dioscorea deltoidea cell cultures by immobilization in polyurethane foam.

Ishida BK et al (1988).
Plant Cell Rep.
DOI:
10.1007/BF00272540
PubMed:
24241764

Diosgenin formation by freely suspended and entrapped plant cell cultures of Dioscorea deltoidea.

Robertson GH et al (1989).
Biotechnol Bioeng.
PubMed:
18588206

Improvement of Diosgenin Yield from Dioscorea deltoidea Plant Cell Cultures by Use of a Non-Traditional Hydrolysis Method.

Drapeau D et al (1986).
Planta Med.
PubMed:
17345412