Eclipta prostrata

Common Names: false daisy

Ethnobotanical Studies

Studies

Microbial Biotransformation of 1-Methyl-L-tryptophan into Herbicidal Indole Alkaloids by Endophytic Fungus Nigrospora chinensis GGY-3.

Summary

GGY-3 transformed 1-MT into new and known indole alkaloids using a Friedel-Crafts reaction. Some compounds showed strong herbicidal activity on dicotyledon weeds, comparable to penoxsulam.

Phytochemistry
Wang B et al (2024).
J Org Chem.
DOI:
10.1021/acs.joc.4c01514
PubMed:
39239664

Eclipta prostrata improves alveolar development of bronchopulmonary dysplasia via suppressing the NLRP3 inflammasome in a DLD-dependent manner.

Zheng X et al (2024).
Pediatr Pulmonol.
DOI:
10.1002/ppul.27209
PubMed:
39115441

Ecliptasaponin A protects heart against acute ischemia-induced myocardial injury by inhibition of the HMGB1/TLR4/NF-κB pathway.

Summary

Eclipta prostrata is a Chinese herb with various health benefits, including anti-inflammatory, liver protection, and antioxidant effects. Ecliptasaponin A, found in the herb, shows strong anti-inflammatory abilities, making it beneficial for treating inflammatory conditions.

CardiologyImmunology
Ge S et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118612
PubMed:
39047883

Bithiophene and coumestan derivatives from Eclipta prostrata (L.) L. and their hepatoprotective activity.

Giang LT et al (2024).
J Asian Nat Prod Res.
DOI:
10.1080/10286020.2024.2364912
PubMed:
38869195

Integrated spatial metabolomics and transcriptomics decipher the hepatoprotection mechanisms of wedelolactone and demethylwedelolactone on non-alcoholic fatty liver disease.

Genetics
Chen P et al (2024).
J Pharm Anal.
DOI:
10.1016/j.jpha.2023.11.017
PubMed:
38655398

Enhanced sun protection factor of octocrylene with green tea and bhringraj extracts.

M P, B N and T K (2024).
Cutan Ocul Toxicol.
DOI:
10.1080/15569527.2024.2340440
PubMed:
38608452

Assessment of hemostatic ability of biomaterial based on chitosan and Eclipta prostrata L. extract.

Linh NN et al (2024).
Biomed Mater.
DOI:
10.1088/1748-605X/ad386e
PubMed:
38537280

Ethanol extract of Eclipta prostrata induces multiple myeloma ferroptosis via Keap1/Nrf2/HO-1 axis.

Summary

Study showed Eclipta prostrata, a Chinese plant, has potential anti-tumor effects in multiple myeloma, a difficult-to-treat blood cancer. Could lead to new treatment options for MM patients.

Cancer
Li W et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155401
PubMed:
38507850

Unlocking Therapeutic Potential: Comprehensive Extraction, Profiling, and Pharmacological Evaluation of Bioactive Compounds from Eclipta alba (L.) Hassk. for Dermatological Applications.

Summary

This review explores the extraction, separation, and identification of bioactive compounds from plant for potential use in skin diseases. Research gaps exist, but this weed plant has potential for skincare products, anti-inflammatory agents, and dermatological treatments.

Review Dermatology
Myo H, Liana D and Phanumartwiwath A (2023).
Plants (Basel).
DOI:
10.3390/plants13010033
PubMed:
38202343

Antioxidant and Antiproliferative Activities of Eclipta prostrata (L.) L. Extract and Isolated Compounds.

Summary

A study found that extracts contain two flavonoids with antioxidant properties, particularly in the ethyl acetate extract. The extract also showed potential as an anticancer agent by reducing cell viability and inducing apoptosis.

CancerImmunology
Yang J et al (2023).
Molecules.
DOI:
10.3390/molecules28217354
PubMed:
37959773

Assessment of the Chemical Profile and Potential Medical Effects of a Flavonoid-Rich Extract of Eclipta prostrata L. Collected in the Central Highlands of Vietnam.

Phytochemistry
Phan TKP et al (2023).
Pharmaceuticals (Basel).
DOI:
10.3390/ph16101476
PubMed:
37895947

The mechanism of Qijing Mingmu decoction on cellular senescence of conjunctivochalasis.

Xiang M et al (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-04138-x
PubMed:
37644481

A methanolic extract of Eclipta prostrata (L.) L. decreases inflammation in a murine model of chronic allergic asthma via inhibition of the NF-kappa-B pathway.

Summary

The study investigated the anti-inflammatory effects of Eclipta prostrata extract in chronic asthma models. The extract showed potential for treating lung inflammation, providing a potential alternative for asthma management.

AsthmaImmunology
Morel LJF et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116930
PubMed:
37487966

First Report of 16SrII Group Related Phytoplasma Associated with Areca Palm Yellow Leaf Disease on Areca catechu in China.

Lin Z et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-03-23-0587-PDN
PubMed:
37467130

Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin.

Hasatsri S et al (2023).
Pharmaceuticals (Basel).
DOI:
10.3390/ph16050685
PubMed:
37242467

Echinocystic acid induces the apoptosis, and inhibits the migration and invasion of non-small cell lung cancer cells.

Summary

Echinocystic acid (EA), a natural compound found in Eclipta prostrata, has shown anticancer properties in previous studies. In this study, EA was tested on non-small cell lung cancer (NSCLC) cells. The results showed that EA inhibited the growth, migration, and invasion of NSCLC cells, as well as induced cell cycle arrest and apoptosis. Further analysis revealed that EA targeted the PI3K/Akt/mTOR pathway. Moreover, EA inhibited tumor growth and induced apoptosis in NSCLC tumor xenografts in mice. These findings suggest that EA could be a potential therapeutic option for NSCLC.

Cancer
Zhu D et al (2023).
Med Oncol.
DOI:
10.1007/s12032-023-02029-2
PubMed:
37202561

Chinese Ecliptae herba (Eclipta prostrata (L.) L.) extract and its component wedelolactone enhances osteoblastogenesis of bone marrow mesenchymal stem cells via targeting METTL3-mediated m6A RNA methylation.

Genetics
Tian S et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116433
PubMed:
37004744

Discovery of the radio-protecting effect of Ecliptae Herba, its constituents and targeting p53-mediated apoptosis in vitro and in vivo.

Cancer
Wu J et al (2023).
Acta Pharm Sin B.
DOI:
10.1016/j.apsb.2022.09.003
PubMed:
36970216

Mathematical Modelling and Statistical Approach in Tannery Wastewater Treatment.

Meenachi S, Kandasamy S and Sukantha TA (2023).
Water Environ Res.
DOI:
10.1002/wer.10851
PubMed:
36889290

Regulation of SIRT1-TLR2/TLR4 pathway in cell communication from macrophages to hepatic stellate cells contribute to alleviates hepatic fibrosis by Luteoloside.

Immunology
Xiu M et al (2023).
Acta Histochem.
DOI:
10.1016/j.acthis.2022.151989
PubMed:
36529079

Effects of Piper betle L. Extract and Allelochemical Eugenol on Rice and Associated Weeds Germination and Seedling Growth.

Choopayak C et al (2022).
Plants (Basel).
DOI:
10.3390/plants11233384
PubMed:
36501422

Punicalagin: a monomer with anti-Eimeria tenella effect from fruit peel of Punica granatum L.

Yang Y et al (2022).
Poult Sci.
DOI:
10.1016/j.psj.2022.102100
PubMed:
36055031

The potential of Brazilian native plant species used in the therapy for snakebites: A literature review.

Review
Konrath EL et al (2022).
Toxicon.
DOI:
10.1016/j.toxicon.2022.08.002
PubMed:
35952835

Wedelolactone facilitates the early development of parthenogenetically activated porcine embryos by reducing oxidative stress and inhibiting autophagy.

Wang XQ et al (2022).
PeerJ.
DOI:
10.7717/peerj.13766
PubMed:
35910774

Biosynthetic studies through feeding experiments in Eclipta prostrata (L.) L. hairy roots.

Lopes AA et al (2022).
Plant Cell Tissue Organ Cult.
DOI:
10.1007/s11240-022-02342-0
PubMed:
35875188

Leaf vein disease in Nelumbo nucifera caused by Nigrospora pyriformis infection in China.

Gong X et al (2022).
Plant Dis.
DOI:
10.1094/PDIS-04-22-0925-PDN
PubMed:
35722915

First Report of 'Candidatus Phytoplasma aurantifolia' Associated with the Invasive Weed Eclipta prostrata (L.) in Taiwan.

Liao PQ et al (2022).
Plant Dis.
DOI:
10.1094/PDIS-03-22-0504-PDN
PubMed:
35442051

Eclipta prostrata (L.) L. (Asteraceae): Ethnomedicinal Uses, Chemical Constituents, and Biological Activities.

Review Ethnobotany
Timalsina D and Devkota HP (2021).
Biomolecules.
DOI:
10.3390/biom11111738
PubMed:
34827736