Embelia ribes

Ethnobotanical Studies

Studies

Medicinal potential of embelin and its nanoformulations: An update on the molecular mechanism and various applications.

Review
Ali A et al (2024).
Iran J Basic Med Sci.
DOI:
10.22038/ijbms.2024.77888.16850
PubMed:
39229578

Synthesis of novel rapanone derivatives via organocatalytic reductive C-alkylation: biological evaluation of antioxidant properties, in vivo zebrafish embryo toxicity, and docking studies.

Immunology
Mariyappan V, Munuswamy-Ramanujam G and Ramasamy M (2023).
RSC Med Chem.
DOI:
10.1039/d3md00564j
PubMed:
38389875

Neuroprotective effects of Embelin in an ethidium bromide-induced multiple sclerosis in rats: Modulation of p38 MAPK signaling pathway.

Summary

Researchers studied the effects of embelin on the p38 MAPK pathway in a mouse model of MS. Embelin showed potential as a therapeutic agent for MS due to its anti-inflammatory properties.

ImmunologyNeuroscience
Anika, Singh S and Rimpi (2024).
Int Immunopharmacol.
DOI:
10.1016/j.intimp.2024.111639
PubMed:
38335654

Embelin: A multifaceted anticancer agent with translational potential in targeting tumor progression and metastasis.

Summary

Embelin from Embelia plants inhibits cancer cell growth via multiple mechanisms, making it a promising anticancer agent supported by scientific literature. Consider its potential for your lab's research on cancer treatment.

Review Cancer
Kamath AJ et al (2023).
EXCLI J.
DOI:
10.17179/excli2023-6590
PubMed:
38234968

Nicotine promotes epithelial to mesenchymal transition and gemcitabine resistance via hENT1/RRM1 signalling in pancreatic cancer and chemosensitizing effects of Embelin-a naturally occurring benzoquinone.

Cancer
Prashanth N et al (2024).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2023.169727
PubMed:
38163613

Synthesis and characterisation of copper acetate mediated oxidative coupled product of naturally occurring hydroxy benzoquinone, embelin and its in vitro and in vivo cytotoxic studies in Dalton Lymphoma ascites tumour cells.

Babu A et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2291822
PubMed:
38134270

Growth inhibitory effect of selected quinones from Indian medicinal plants against Theileria annulata.

Kiriyanthan RM et al (2023).
Exp Parasitol.
DOI:
10.1016/j.exppara.2023.108622
PubMed:
37758051

Embelin targets PI3K/AKT and MAPK in age-related ulcerative colitis: an integrated approach of microarray analysis, network pharmacology, molecular docking, and molecular dynamics.

GastroenterologyImmunology
Javali PS and Thirumurugan K (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2255674
PubMed:
37691456

Isolation and in-silico approach of Modified Embelin derivative from Embelia ribes fruits as anti-Alzheimer agent.

Rupesh R, Mohankumar R and Sabarathinam S (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2255920
PubMed:
37690004

Assessing the Impact of Geographical Distribution and Genetic Diversity on Metabolic Profiles of a Medicinal Plant, Embelia ribes Burm. f.

Raskar S et al (2022).
Plants (Basel).
DOI:
10.3390/plants11212861
PubMed:
36365314

Reviewing the Traditional/Modern Uses, Phytochemistry, Essential Oils/Extracts and Pharmacology of Embelia ribes Burm.

Review Phytochemistry
Sharma V et al (2022).
Antioxidants (Basel).
DOI:
10.3390/antiox11071359
PubMed:
35883850

Plants with potential anti-ulcerogenic activity and possible mechanism of actions based on their phyto-constitutional profile.

Review
Keny ES and Kale PP (2022).
J Complement Integr Med.
DOI:
10.1515/jcim-2021-0264
PubMed:
35152595

Antipsychotic activity of embelin isolated from Embelia ribes: A preliminary study.

Durg S et al (2017).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2017.03.085
PubMed:
28376400

Antidiabetic activity of Embelia ribes, embelin and its derivatives: A systematic review and meta-analysis.

Summary

Embelia ribes (ER) and embelin show promise in treating diabetes mellitus by significantly reducing blood glucose and improving insulin levels in experimental rat studies. Further clinical trials are needed to confirm these findings.

Meta-Analysis Diabetes
Durg S et al (2017).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2016.12.001
PubMed:
27984799

Embelin and Its Role in Chronic Diseases.

Review
Lu H et al (2016).
Adv Exp Med Biol.
PubMed:
27671825

Embelia ribes ameliorates lipopolysaccharide-induced acute respiratory distress syndrome.

Shirole RL, Shirole NL and Saraf MN (2015).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2015.03.009
PubMed:
25818695

α-Glucosidase inhibitors from the stems of Embelia ribes.

Dang PH et al (2014).
Phytother Res.
DOI:
10.1002/ptr.5175
PubMed:
24849650