Epimedium brevicornu

Ethnobotanical Studies

Studies

Characterizing seed dormancy in Epimedium brevicornu Maxim.: Development of novel chill models and determination of dormancy release mechanisms by transcriptomics.

Genetics
Li P et al (2024).
BMC Plant Biol.
DOI:
10.1186/s12870-024-05471-0
PubMed:
39112934

UV-B Radiation Enhances Epimedium brevicornu Maxim. Quality by Improving the Leaf Structure and Increasing the Icaritin Content.

Li P et al (2024).
Plants (Basel).
DOI:
10.3390/plants13131720
PubMed:
38999560

The carrier function and inhibition effect on benign prostatic hyperplasia of a glucan from Epimedium brevicornu Maxim.

Yan L et al (2024).
Carbohydr Polym.
DOI:
10.1016/j.carbpol.2024.122316
PubMed:
38858029

Comparing the pharmacological effects of the prepared folium of Epimedium brevicornu Maxim. and Epimedium sagittatum Maxim. on kidney-Yang deficiency syndrome and liver injury complications.

Zheng X et al (2024).
Fitoterapia.
DOI:
10.1016/j.fitote.2024.106006
PubMed:
38744386

Prenylated chromones and flavonoids isolated from the roots of Flemingia macrophylla and their anti-lung cancer activity.

Summary

Researchers investigated prenylated flavonoids in Flemingia macrophylla, which regulate the p53 protein. The study aims to identify these compounds, evaluate their activity, establish their structure-activity relationship, and understand their mechanisms. This research can provide potential candidates for the development of antitumor drugs.

CancerPhytochemistry
Wang B et al (2023).
Chin Med.
DOI:
10.1186/s13020-023-00860-3
PubMed:
37996917

AR/RKIP pathway mediates the inhibitory effects of icariin on renal fibrosis and endothelial-to-mesenchymal transition in type 2 diabetic nephropathy.

Summary

Researchers found that icariin, a compound extracted from Herba epimedium brevicornu maxim, can improve nephropathy disease, supporting the traditional use of this plant and suggesting therapeutic benefits for kidney-related issues.

Diabetes
Yao W et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117414
PubMed:
37977422

One new prenylated flavonoid with cytotoxic activity from Epimedium brevicornu maxim.

Summary

Scientists discovered and identified four flavonoids from maxim leaves. One of them showed moderate cytotoxicity against Lewis Lung cancer cells, while the others had weak cytotoxic effects.

Phytochemistry
Zhang H et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2282114
PubMed:
37966979

Icariin induces developmental toxicity via thyroid hormone disruption in zebrafish larvae.

Summary

Icariin, a natural compound from a Chinese herb, was found to negatively affect the development of zebrafish embryos. It disrupted thyroid development and hormone synthesis, indicating potential toxicity. Risk assessments should be done before using ICA in clinical practice.

Endocrinology
Wu M et al (2023).
Food Chem Toxicol.
DOI:
10.1016/j.fct.2023.114155
PubMed:
37898232

Icariin inhibits hypertrophy by regulation of GPER1 and CaMKII/HDAC4/MEF2C signaling crosstalk in ovariectomized mice.

Zhao W et al (2023).
Chem Biol Interact.
DOI:
10.1016/j.cbi.2023.110728
PubMed:
37739049

Icariin-Curcumol promotes docetaxel sensitivity in prostate cancer through modulation of the PI3K-Akt signaling pathway and the Warburg effect.

Cancer
Xu W et al (2023).
Cancer Cell Int.
DOI:
10.1186/s12935-023-03042-1
PubMed:
37660001

Icariin improves learning and memory function in Aβ(1-42)-induced AD mice through regulation of the BDNF-TrκB signaling pathway.

Neuroscience
Wan M et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117029
PubMed:
37579923

Icaritin Promotes Myelination by Simultaneously Enhancing the Proliferation and Differentiation of Oligodendrocyte Precursor Cells.

Yang F et al (2023).
Molecules.
DOI:
10.3390/molecules28155837
PubMed:
37570807

The pharmacological effects and safety of the raw and prepared folium of Epimedium brevicornu Maxim. on improving kidney-yang deficiency syndrome and sexual dysfunction.

Wang K et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1233468
PubMed:
37521477

Evaluate the photosynthesis and chlorophyll fluorescence of Epimedium brevicornu Maxim.

Zaiyou J et al (2022).
Sci Rep.
DOI:
10.1038/s41598-022-24165-x
PubMed:
36376438

Icaritin, a metabolite of Icarrin, Alleviates non-alcoholic fatty liver disease via inhibition of lipogenesis and ER stress.

Yu P et al (2022).
Eur J Pharmacol.
DOI:
10.1016/j.ejphar.2022.175378
PubMed:
36372277

Seed Vigour and Morphological and Physiological Characteristics of Epimedium brevicornu Maxim: In Different Stages of Seed Development.

Li P et al (2022).
Plants (Basel).
DOI:
10.3390/plants11182399
PubMed:
36145800

The complete chloroplast genome of Epimedium brevicornu Maxim (Berberidaceae), a traditional Chinese medicine herb.

Genetics
Zhang Y et al (2020).
Mitochondrial DNA B Resour.
DOI:
10.1080/23802359.2019.1710593
PubMed:
33366659

Simultaneous Preparation and Comparison of the Osteogenic Effects of Epimedins A - C and Icariin from Epimedium brevicornu.

Guo Y, Wang X and Gao J (2018).
Chem Biodivers.
DOI:
10.1002/cbdv.201700578
PubMed:
29451707

STUDY ON THE DIFFERENCES OF MAJOR PHARMACEUTICAL INGREDIENTS IN DIFFERENT PARTS AND PROCESSED MEDICINAL MATERIAL OF EPIMEDIUM BREVICORNU MAXIM IN TAIHANG MOUNTAIN.

Zai-you J et al (2015).
Nutr Hosp.
DOI:
10.3305/nh.2015.32.2.8927
PubMed:
26268128