Eucommia ulmoides

Ethnobotanical Studies

Studies

Advances in Eucommia ulmoides polysaccharides: extraction, purification, structure, bioactivities and applications.

Review
Sun Y et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1421662
PubMed:
39221141

A salt/salt aqueous two-phase system based on pH-switchable deep eutectic solvent for the extraction and separation of mulberry polysaccharides.

Lei T et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2024.141024
PubMed:
39217751

Phosphate adsorption characteristics of CeO(2)-loaded, Eucommia ulmoides leaf residue biochar.

Yue Y et al (2024).
Environ Pollut.
DOI:
10.1016/j.envpol.2024.124657
PubMed:
39098643

Non-targeted metabolomics and explainable artificial intelligence: Effects of processing and color on coniferyl aldehyde levels in Eucommiae cortex.

Pan Y et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2024.140564
PubMed:
39089015

Effects of Eucommia ulmoides leaf extract on xanthine oxidase and chronic kidney disease induced by adenine in rats.

Song H et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2383993
PubMed:
39049541

Network pharmacology analysis of the regulatory effects and mechanisms of ALAE on sow reproduction in vivo and in vitro.

Zhao L et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118525
PubMed:
38992402

Preparation techniques, structural features, and bioactivities of Eucommia ulmoides polysaccharides: A review.

Review
Yu P et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.133686
PubMed:
38972653

Aucubin Alleviates Chronic Obstructive Pulmonary Disease by Activating Nrf2/HO-1 Signaling Pathway.

Liu T, Li Y and Hu N (2024).
Cell Biochem Biophys.
DOI:
10.1007/s12013-024-01354-1
PubMed:
38967902

Differential responses of the phyllosphere abundant and rare microbes of Eucommia ulmoides to phytohormones.

Shao Q et al (2024).
Microbiol Res.
DOI:
10.1016/j.micres.2024.127798
PubMed:
38964073

Total Flavonoids Isolated from the Leaves of Eucommia ulmoides Augment Peak Bone Mass in Female Rats and Show no Side Effects in Other Organs.

Summary

Scientists studied Eucommia ulmoides, a tree in China known for its medicinal properties. It can prevent osteoporosis and arthritis, and help heal bone fractures. Useful for potential medical treatments.

Phytochemistry
Zhang Y et al (2024).
Curr Pharm Des.
DOI:
10.2174/0113816128298755240613100018
PubMed:
38963117

Investigating the Pharmacological Mechanisms of Total Flavonoids from Eucommia ulmoides Oliver Leaves for Ischemic Stroke Protection.

Summary

Study shows total flavonoids from EUL leaves can protect against nerve damage from ischemia by reducing oxidative stress, increasing cell survival rates, and modulating related pathways, suggesting potential therapeutic effects for ischemic stroke treatment.

CardiologyNeurosciencePhytochemistry
Qin J et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25116271
PubMed:
38892459

Effect of dietary Eucommia ulmoides oliver polysaccharide on immune function and meat quality of Songliao Black Pigs.

Liang Y et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-64257-4
PubMed:
38886454

Untargeted metabolomics revealed the mechanism of aucubin on glucocorticoid-induced osteoporosis in mice through modulating arachidonic acid metabolism.

Arthritis
Wang H et al (2024).
J Pharm Biomed Anal.
DOI:
10.1016/j.jpba.2024.116273
PubMed:
38878451

Polysaccharides from Eucommia ulmoides Oliv. leaves alleviates alcohol-induced mouse brain injury and BV-2 microglial dysfunction.

Summary

EULP from Eucommia ulmoides leaves protects against acute alcohol-induced brain injury by improving neurobehavioral deficits, neurotransmitter damage, and microglial dysfunction. Consider employing EULP as a potential therapeutic agent for alcohol-induced brain damage.

Neuroscience
Li Y et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.132887
PubMed:
38851621

Establishment of an Efficient Protoplast Isolation and Transfection Method for Eucommia ulmoides Oliver.

Hu B et al (2024).
Front Biosci (Landmark Ed).
DOI:
10.31083/j.fbl2905187
PubMed:
38812327

Feeding Eucommia ulmoides extract enhances protection against high-temperature stress in chicks.

Huang Y et al (2024).
Poult Sci.
DOI:
10.1016/j.psj.2024.103827
PubMed:
38801811

Cloning and functional characterization of the peptide deformylase encoding gene EuPDF1B from Eucommia ulmoides Oliv.

Genetics
Wang Y and Zhao DG (2024).
Sci Rep.
DOI:
10.1038/s41598-024-62512-2
PubMed:
38773239

Histochemical studies on the distribution and accumulation of trans-polyisoprene in the rubber-producing plant Eucommia ulmoides.

Ma XF et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.132405
PubMed:
38754661

Eucommia ulmoides Leaves Alleviate Cognitive Dysfunction in Dextran Sulfate Sodium (DSS)-Induced Colitis Mice through Regulating JNK/TLR4 Signaling Pathway.

Summary

Study shows AEEL alleviates cognitive dysfunction in mice with colitis by improving gut-brain interaction, protecting against inflammation and oxidative damage. Potential natural remedy for ulcerative colitis.

GastroenterologyNeuroscience
Lee HS et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25074063
PubMed:
38612870

Polysaccharides from Eucommia ulmoides Oliv. Leaves Alleviate Acute Alcoholic Liver Injury by Modulating the Microbiota-Gut-Liver Axis in Mice.

Gastroenterology
Li Y et al (2024).
Foods.
DOI:
10.3390/foods13071089
PubMed:
38611393

Biological properties and potential application of extracts and compounds from different medicinal parts (bark, leaf, staminate flower, and seed) of Eucommia ulmoides: A review.

Review
Peng M, Zhou Y and Liu B (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e27870
PubMed:
38545153

Effects of Dietary Eucommia ulmoides Leaf Extract Supplementation on Growth Performance, Meat Quality, Antioxidant Capacity, and Lipid Metabolism of Finishing Pigs.

Immunology
Han M et al (2024).
Antioxidants (Basel).
DOI:
10.3390/antiox13030320
PubMed:
38539852

Geniposidic acid alleviates osteoarthritis progression through inhibiting inflammation and chondrocytes ferroptosis.

Immunology
Sun J et al (2024).
J Cell Mol Med.
DOI:
10.1111/jcmm.18228
PubMed:
38520209

Aqueous extract of fermented Eucommia ulmoides leaves alleviates hyperlipidemia by maintaining gut homeostasis and modulating metabolism in high-fat diet fed rats.

Gastroenterology
Duan Y et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.155291
PubMed:
38518640

Physiology and transcriptome of Eucommia ulmoides seeds at different germination stages.

Summary

Study shows plant hormones ABA, GA, IAA play crucial role in seed germination of Eucommia. Understanding this can improve seedling growth and market value.

Genetics
Liu J et al (2024).
Plant Signal Behav.
DOI:
10.1080/15592324.2024.2329487
PubMed:
38493506

Aucubin produces anti-osteoporotic effects under mechanical stretch stress and orthodontic tooth movement.

Huang J et al (2024).
Chem Biol Interact.
DOI:
10.1016/j.cbi.2024.110955
PubMed:
38492842

Promoting the disassemble and enzymatic saccharification of bamboo shoot shells via efficient hydrated alkaline deep eutectic solvent pretreatment.

Hu Q et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.130702
PubMed:
38471607

Development of machine learning models using multi-source data for geographical traceability and content prediction of Eucommia ulmoides leaves.

Zhang Y, Zhu X and Wang- Y (2024).
Spectrochim Acta A Mol Biomol Spectrosc.
DOI:
10.1016/j.saa.2024.124136
PubMed:
38467098

Engineering Bacterial Biofilm Development and Structure via Regulation of Silver Nanoparticle Density in Graphene Oxide Composite Coating.

Wang S et al (2024).
JACS Au.
DOI:
10.1021/jacsau.4c00008
PubMed:
38425932

EuTGA1, a bZIP transcription factor, positively regulates EuFPS1 expression in Eucommia ulmoides.

Shi R et al (2024).
Gene.
DOI:
10.1016/j.gene.2024.148278
PubMed:
38360121

Combination of a Deep Eutectic Solvent and Macroporous Resin for Green Recovery of Iridoids, Chlorogenic Acid, and Flavonoids from Eucommia ulmoides Leaves.

Phytochemistry
Liao Y et al (2024).
Molecules.
DOI:
10.3390/molecules29030737
PubMed:
38338480

Dietary supplementation of water extract of Eucommia ulmoides bark improved caecal microbiota and parameters of health in white-feathered broilers.

Gastroenterology
Lu M et al (2024).
J Anim Physiol Anim Nutr (Berl).
DOI:
10.1111/jpn.13929
PubMed:
38324000

A review of "plant gold" Eucommia ulmoides Oliv.: A medicinal and food homologous plant with economic value and prospect.

Review
Bao L et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e24851
PubMed:
38312592

Extraction and characterisation of kudzu root residue lignin based on deep eutectic solvents.

Han X et al (2024).
Phytochem Anal.
DOI:
10.1002/pca.3328
PubMed:
38279552

Extraction and Purification of Aucubin from Eucommia ulmoides Seed Draff in Natural Deep Eutectic Solvents Using Macroporous Resins.

Liao Y et al (2023).
ACS Omega.
DOI:
10.1021/acsomega.3c08332
PubMed:
38222590

Integrated Transcriptomics and Metabolomics Analysis Promotes the Understanding of Adventitious Root Formation in Eucommia ulmoides Oliver.

Genetics
Du Q et al (2024).
Plants (Basel).
DOI:
10.3390/plants13010136
PubMed:
38202444

Optimization of Flavonoid Extraction from Eucommia ulmoides pollen using Respond Surface Methodology and its biological activities.

Phytochemistry
Zhu J et al (2024).
Chem Biodivers.
DOI:
10.1002/cbdv.202301308
PubMed:
38163260

Dynamic changes of endophytic bacteria in the bark and leaves of medicinal plant Eucommia ulmoides in different seasons.

Liang X et al (2023).
Microbiol Res.
DOI:
10.1016/j.micres.2023.127567
PubMed:
38103467

Network pharmacology and molecular docking elucidate potential mechanisms of Eucommia ulmoides in hepatic ischemia-reperfusion injury.

Summary

Eucommia ulmoides (EU) has potential for treating hepatic ischemia-reperfusion injury (HIRI) through targeting multiple pathways. EU contains bioactive compounds such as quercetin and gallic acid that positively regulate gene expression and apoptotic processes. Key pathways involved include cancer, RAGE signaling, lipid metabolism, and apoptotic pathways.

Cardiology
Ma X et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-47918-8
PubMed:
38001230

Leaf phenotypic variation and its response to environmental factors in natural populations of Eucommia ulmoides.

Gong H et al (2023).
BMC Plant Biol.
DOI:
10.1186/s12870-023-04583-3
PubMed:
37964219

Dietary supplementation of Eucommia leaf extract to growing-finishing pigs alters muscle metabolism and improves meat quality.

Shen Z et al (2023).
Anim Biosci.
DOI:
10.5713/ab.23.0220
PubMed:
37946427

Comprehensive genomic characterisation of the NAC transcription factor family and its response to drought stress in Eucommia ulmoides.

Wang Q et al (2023).
PeerJ.
DOI:
10.7717/peerj.16298
PubMed:
37901460

Beneficial effect and mechanism of natural resourced polysaccharides on regulating bone metabolism through intestinal flora: A review.

Summary

Certain polysaccharides can improve gut microbiota and regulate bone metabolism. Factors like molecular weight and composition influence effectiveness, enhancing bone health. This can guide treatment of bone metabolic disorders.

Review Gastroenterology
Zhou Y et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.127428
PubMed:
37838110

Deciphering the effect of phytohormones on the phyllosphere microbiota of Eucommia ulmoides.

Summary

Phytohormones in Eucommia ulmoides leaves affect plant-microbe communication. Older leaves have lower levels of certain phytohormone components, but a more diverse microbial community. IAA and IP play key roles. The findings offer insights for sustainable agriculture and forestry management.

Gastroenterology
Shao Q et al (2023).
Microbiol Res.
DOI:
10.1016/j.micres.2023.127513
PubMed:
37837828

Efficient separation and production of high-quality rubber, lignin nanoparticles and fermentable sugars from Eucommia ulmoides pericarp via deep eutectic solvent pretreatment.

Yao X et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.127221
PubMed:
37797857

Geniposide stimulates autophagy by activating the GLP-1R/AMPK/mTOR signaling in osteoarthritis chondrocytes.

Huang J et al (2023).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2023.115595
PubMed:
37769389

An integrated process by ultrasonic enhancement in the deep eutectic solvents system for extraction and separation of chlorogenic acid from Eucommia ulmoides leaves.

Meng Y et al (2023).
Ultrason Sonochem.
DOI:
10.1016/j.ultsonch.2023.106588
PubMed:
37690261

Cloning and functional analysis prohibitins protein-coding gene EuPHB1 in Eucommia ulmoides Oliver.

Summary

Prohibitins, like EuPHB1, are important proteins in cells. Overexpressing EuPHB1 in tobacco caused leaves to turn yellow and shrink. This is because it disrupted the hormone and auxin signaling pathways. It also increased energy production in mitochondria, supporting rapid cell division.

Genetics
Xu T and Zhao D (2023).
Gene.
DOI:
10.1016/j.gene.2023.147758
PubMed:
37661028

Geniposide suppressed OX-LDL-induced osteoblast apoptosis by regulating the NRF2/NF-κB signaling pathway.

Summary

Scientists investigated the effect of geniposide, a natural compound from Eucommia ulmoides, on osteoporosis. Geniposide was found to protect against the development of osteoporosis induced by cholesterol accumulation. This research can contribute to the development of potential drugs for treating osteoporosis.

Immunology
Xiao Y et al (2023).
J Orthop Surg Res.
DOI:
10.1186/s13018-023-04125-5
PubMed:
37649066

Antihypertensive activity of different components of Veratrum alkaloids through metabonomic data analysis.

Summary

Tossers studied Veratrum alkaloids, once used to treat hypertension, but abandoned due to side effects. Mechanism remains unclear. Relevant because developing new hypertension treatments is crucial.

Phytochemistry
Zhou Z et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.155033
PubMed:
37647672

CO(2)-responsive deep eutectic solvents for the enhanced extraction of hesperidin from Fertile orange peel.

Wang S et al (2023).
Food Chem.
DOI:
10.1016/j.foodchem.2023.137255
PubMed:
37643516

Dual effect of aucubin on promoting VEGFR2 mediated angiogenesis and reducing RANKL-induced bone resorption.

He Y et al (2023).
Chin Med.
DOI:
10.1186/s13020-023-00786-w
PubMed:
37641047

A Study of Molecular Dynamic Simulation and Experimental Performance of the Eucommia Ulmoides Gum-Modified Asphalt.

Yan S et al (2023).
Materials (Basel).
DOI:
10.3390/ma16165700
PubMed:
37629990

Molecular Identification of Acrossocheilus jishouensis (Teleostei: Cyprinidae) and Its Complete Mitochondrial Genome.

Summary

Researchers used DNA barcoding to identify and expand the distribution range of Acrossocheilus jishouensis. The study also revealed genetic characteristics and nonmonophyly between Acrossocheilus and Onychostoma, providing valuable insights for future research on cyprinids.

Genetics
Lan X et al (2023).
Biochem Genet.
DOI:
10.1007/s10528-023-10501-x
PubMed:
37620638

Smartphone-based electrochemical sensor for cost-effective, rapid and on site detection of chlorogenic acid in herbs using biomass-derived hierarchically porous carbon synthesized by a soft-hard dual template method.

Jiang W et al (2023).
Food Chem.
DOI:
10.1016/j.foodchem.2023.137165
PubMed:
37598652

Aucubin improves chronic unpredictable mild stress-induced depressive behavior in mice via the GR/NF-κB/NLRP3 axis.

Summary

The study examined the therapeutic effect of aucubin (AU), the main component of Eucommia ulmoides Oliv (EUO), on depression in mice. AU improved depression-like behavior by promoting intranuclear expression of glucocorticoid receptor (GR) and inhibiting inflammation-driven cell pyroptosis.

ImmunologyNeuroscience
Liu P et al (2023).
Int Immunopharmacol.
DOI:
10.1016/j.intimp.2023.110677
PubMed:
37523973

Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro.

Summary

Eucommia lignans derived from Eucommia ulmoides Oliver have been found to inhibit the progression of diabetic nephropathy (DN) by reducing inflammation and improving renal function through the AR/Nrf2/HO-1/AMPK axis. This suggests that Eucommia lignans could be a potential treatment for DN.

DiabetesPhytochemistry
Huang Q et al (2023).
Chin J Nat Med.
DOI:
10.1016/S1875-5364(23)60427-3
PubMed:
37517819

Study on the substance basis of the efficacy of eucommiae cortex before and after salt processing for the treatment of kidney-yang deficiency syndrome based on the spectrum-effect relationship.

Wu H et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116926
PubMed:
37479066

Quality Marker Discovery and Quality Evaluation of Eucommia ulmoides Pollen Using UPLC-QTOF-MS Combined with a DPPH-HPLC Antioxidant Activity Screening Method.

Immunology
Guo F et al (2023).
Molecules.
DOI:
10.3390/molecules28135288
PubMed:
37446949

Polyethylene glycol modified graphene oxide-silver nanoparticles nanocomposite as a novel antibacterial material with high stability and activity.

Bao Y et al (2023).
Colloids Surf B Biointerfaces.
DOI:
10.1016/j.colsurfb.2023.113435
PubMed:
37437413

Identification of pancreatic lipase inhibitors from Eucommia ulmoides tea by affinity-ultrafiltration combined UPLC-Orbitrap MS and in vitro validation.

Huang H et al (2023).
Food Chem.
DOI:
10.1016/j.foodchem.2023.136630
PubMed:
37352710

Green synthesis of silver nanoparticles using Eucommia ulmoides leaf extract for inhibiting stem end bacteria in cut tree peony flowers.

Ma Z et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1176359
PubMed:
37324696

Enrichment of the flavonoid fraction from Eucommia ulmoides leaves by a liquid antisolvent precipitation method and evaluation of antioxidant activities in vitro and in vivo.

ImmunologyPhytochemistry
Wu M et al (2023).
RSC Adv.
DOI:
10.1039/d3ra00800b
PubMed:
37313520

Characteristics of endophytic bacteria and active ingredients in the Eucommiae cortex from different origins.

Liang X et al (2023).
Front Microbiol.
DOI:
10.3389/fmicb.2023.1164674
PubMed:
37266017

Identification of a Coprinellus strain and its application in Eucommia ulmoides gum extraction by fermenting leaves.

Yang Y et al (2023).
Biotechnol Lett.
DOI:
10.1007/s10529-023-03396-6
PubMed:
37243777

Feasibility study on the use of "Qi-tonifying medicine compound" as an anti-fatigue functional food ingredient based on network pharmacology and molecular docking.

Wu Y et al (2023).
Front Nutr.
DOI:
10.3389/fnut.2023.1131972
PubMed:
37215213

Asperuloside, the bioactive compound in the edible Eucommia ulmoides male flower, delays muscle aging by daf-16 mediated improvement in mitochondrial dysfunction.

Chen Q et al (2023).
Food Funct.
DOI:
10.1039/d3fo01024d
PubMed:
37212195

Supplementary UV-B Radiation Effects on Photosynthetic Characteristics and Important Secondary Metabolites in Eucommia ulmoides Leaves.

Xiao S et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24098168
PubMed:
37175879

Iridoid from Eucommia ulmoides Oliv. Exerts Antiarthritis Effects by Inhibiting the JAK2/STAT3 Signaling Pathway In Vivo and In Vitro.

Immunology
Tang LD et al (2023).
Evid Based Complement Alternat Med.
DOI:
10.1155/2023/4167906
PubMed:
37123081

Quantitative Detection of Natural Rubber Content in Eucommia ulmoides by Portable Pyrolysis-Membrane Inlet Mass Spectrometry.

Guo M et al (2023).
Molecules.
DOI:
10.3390/molecules28083330
PubMed:
37110564

UHPLC-Quadrupole-Exactive-Orbitrap-MS/MS-based putative identification for Eucommiae Folium (Duzhongye) and its quality-marker candidate for pharmacopeia.

Liu S et al (2023).
J Sep Sci.
DOI:
10.1002/jssc.202300041
PubMed:
37102419

Analysis on the thermal decomposition kinetics and storage period of biomass-based lycorine galanthamine.

Qin C, Ling W and Tian C (2023).
Front Chem.
DOI:
10.3389/fchem.2023.1186711
PubMed:
37090243

The NAC transcription factor family in Eucommia ulmoides: Genome-wide identification, characterization, and network analysis in relation to the rubber biosynthetic genes.

Genetics
Zhang S et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1030298
PubMed:
37077635

Extraction of Eucommia ulmoides gum and microbial lipid from Eucommia ulmoides Oliver leaves by dilute acid hydrolysis.

Gao R et al (2023).
Biotechnol Lett.
DOI:
10.1007/s10529-023-03377-9
PubMed:
37071384

The chromosome-level genome of Eucommia ulmoides provides insights into sex differentiation and α-linolenic acid biosynthesis.

Genetics
Du Q et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1118363
PubMed:
37063180

Two Complete Mitochondrial Genomes of Leptobrachium (Anura: Megophryidae: Leptobrachiinae): Characteristics, Population Divergences, and Phylogenetic Implications.

Zhou Q et al (2023).
Genes (Basel).
DOI:
10.3390/genes14030768
PubMed:
36981038

Surface modifications of titanium dental implants with strontium eucommia ulmoides to enhance osseointegration and suppress inflammation.

Immunology
Sun AR et al (2023).
Biomater Res.
DOI:
10.1186/s40824-023-00361-2
PubMed:
36927570

Pharmacological network analysis of the functions and mechanism of kaempferol from Du Zhong in intervertebral disc degeneration (IDD).

Wang X et al (2023).
J Orthop Translat.
DOI:
10.1016/j.jot.2023.01.002
PubMed:
36909862

Intelligent Eucommia ulmoides Rubber/Ionomer Blends with Thermally Activated Shape Memory and Self-Healing Properties.

Wang Q et al (2023).
Polymers (Basel).
DOI:
10.3390/polym15051182
PubMed:
36904423

Network Pharmacology Combined with an Experimental Validation Study to Reveal the Effect and Mechanism of Eucommia ulmoides Leaf Polysaccharide against Immunomodulation.

Cui E et al (2023).
Foods.
DOI:
10.3390/foods12051062
PubMed:
36900578

Genome-wide identification and expression analysis of MADS-box transcription factors reveal their involvement in sex determination of hardy rubber tree (Eucommia ulmoides oliv.).

Genetics
Zhang X et al (2023).
Front Genet.
DOI:
10.3389/fgene.2023.1138703
PubMed:
36896236

Chondroprotective Mechanism of Eucommia ulmoides Oliv.-Glycyrrhiza uralensis Fisch. Couplet Medicines in Knee Osteoarthritis via Experimental Study and Network Pharmacology Analysis.

Arthritis
Wang P et al (2023).
Drug Des Devel Ther.
DOI:
10.2147/DDDT.S397185
PubMed:
36875721

Fermentation performance of oleaginous yeasts on Eucommia ulmoides Oliver hydrolysate: Impacts of the mixed strains fermentation.

Gao R et al (2023).
J Biotechnol.
DOI:
10.1016/j.jbiotec.2023.02.009
PubMed:
36868409

Establishment of Male and Female Eucommia Fingerprints by UPLC Combined with OPLS-DA Model and Its Application.

You J et al (2023).
Chem Biodivers.
DOI:
10.1002/cbdv.202201054
PubMed:
36790137

Structural characterization and anti-osteoporosis effects of polysaccharide purified from Eucommia ulmoides Oliver cortex based on its modulation on bone metabolism.

Song J et al (2023).
Carbohydr Polym.
DOI:
10.1016/j.carbpol.2023.120601
PubMed:
36746570

Potential therapeutic drug targets and pathways prediction for premature ovarian insufficiency -Based on network pharmacologic method.

Endocrinology
Ju S et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.116054
PubMed:
36526095

Traditional application and modern pharmacological research of Eucommia ulmoides Oliv.

Review
Huang L et al (2021).
Chin Med.
DOI:
10.1186/s13020-021-00482-7
PubMed:
34362420

Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet.

EndocrinologyPhytochemistry
Peng MF et al (2021).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2021.113947
PubMed:
33617969

Aucubin Protects Chondrocytes Against IL-1β-Induced Apoptosis In Vitro And Inhibits Osteoarthritis In Mice Model.

Immunology
Wang BW et al (2019).
Drug Des Devel Ther.
DOI:
10.2147/DDDT.S210220
PubMed:
31631977

Eucommia ulmoides Oliver: A Potential Feedstock for Bioactive Products.

Review
Zhu MQ and Sun RC (2018).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.8b01312
PubMed:
29745662