Euphorbia hirta

Common Names: asthma spurge, pillpod sandmat, pillpod spurge

Ethnobotanical Studies

Studies

An investigation of the pigments, antioxidants and free radical scavenging potential of twenty medicinal weeds found in the southern part of Bangladesh.

Sumi MJ et al (2024).
PeerJ.
DOI:
10.7717/peerj.17698
PubMed:
39071122

Using Multiscale Molecular Modeling to Analyze Possible NS2b-NS3 Protease Inhibitors from Philippine Medicinal Plants.

Cordero AMF and Gonzales AA 3rd (2024).
Curr Issues Mol Biol.
DOI:
10.3390/cimb46070451
PubMed:
39057092

In silico and in vitro studies for the identification of small molecular inhibitors from Euphorbia hirta Linn for rheumatoid arthritis: targeting TNF-α-mediated inflammation.

ArthritisImmunology
Velmurugan Y et al (2024).
Mol Divers.
DOI:
10.1007/s11030-024-10900-1
PubMed:
38884873

Antioxidant and Anti-Inflammatory Activity of the Ethanolic Extract of Euphorbia Hirta Leaf Extract: An In Vitro and In Silico Study.

Immunology
Praveen G et al (2024).
J Pharm Bioallied Sci.
DOI:
10.4103/jpbs.jpbs_591_23
PubMed:
38882735

Euphorbia hirta nanoextract as a piezoelectric ultrasonic scaler coolant in gingivitis treatment in a Wistar rat model.

Nuryanti A et al (2023).
J Taibah Univ Med Sci.
DOI:
10.1016/j.jtumed.2023.09.004
PubMed:
37868098

Assessment of plant ecological variability and heavy metal accumulation potential in naturally growing plant species of Pakhar bauxite mine site, Jharkhand, India.

Kumari K, Chakraborty S and Bauddh K (2023).
Chemosphere.
DOI:
10.1016/j.chemosphere.2023.140316
PubMed:
37793547

Leaf and stem anatomical characterization of Euphorbia hirta L., a tolerant species to glyphosate.

Chapeta ACO et al (2023).
J Environ Sci Health B.
DOI:
10.1080/03601234.2023.2177462
PubMed:
36775896

Utilization of industrial waste - Liquid cheese whey for the batch fermentation of lovastatin using Fusarium nectrioides (MH173849) an endophytic fungus: Screening, production and characterization.

Manogaran S et al (2023).
Chemosphere.
DOI:
10.1016/j.chemosphere.2023.137947
PubMed:
36706809

Determination and Quantification of Phytochemicals from the Leaf Extract of Parthenium hysterophorus L. and Their Physio-Biochemical Responses to Several Crop and Weed Species.

Phytochemistry
Bashar HMK et al (2022).
Plants (Basel).
DOI:
10.3390/plants11233209
PubMed:
36501249

Gallic acid a flavonoid isolated from Euphorbia hirta antagonizes gamma radiation induced radiotoxicity in lymphocytes in vitro.

Immunology
Chakka R et al (2022).
J Complement Integr Med.
DOI:
10.1515/jcim-2022-0196
PubMed:
36398419

Protective effect of Euphorbia thymifolia and Euphorbia hirta against carbon tetrachloride-induced hepatotoxicity in Wistar rats.

Balasubramanian B et al (2022).
Drug Dev Ind Pharm.
DOI:
10.1080/03639045.2022.2122985
PubMed:
36268597

Silver nanoparticles synthesized by Euphorbia hirta exhibited antibacterial activity and induced apoptosis through downregulation of PI3Kγ mediated PI3K/Akt/mTOR/p70S6K in human lung adenocarcinoma A549 cells.

Ramachandran R, Parthasarathy R and Dhayalan S (2022).
Environ Toxicol.
DOI:
10.1002/tox.23643
PubMed:
36073799

Interactive deciphering electron-shuttling characteristics of agricultural wastes with potential bioenergy-steered anti-COVID-19 activity via microbial fuel cells.

Summary

In a new study, researchers investigated the potential of certain indigenous herbs from agricultural waste to stimulate bioenergy and biorefinery for developing anti-COVID-19 drugs. Their findings suggested that herbs rich in electron shuttle-steering and virus transmission-resisting compounds could be promising candidates. This study is a preliminary exploration of this topic and highlights potential avenues for further research in developing treatments for COVID-19.

COVID-19
Tsai PW et al (2022).
J Taiwan Inst Chem Eng.
DOI:
10.1016/j.jtice.2022.104426
PubMed:
35756346

Anti-Dengue Screening on Several Vietnamese Medicinal Plants: Experimental Evidences and Computational Analyses.

Thao TTP et al (2022).
Chem Biodivers.
DOI:
10.1002/cbdv.202101026
PubMed:
35698444

Formulation, characteristics and anti-bacterial effects of Euphorbia hirta L. mouthwash.

Iskandar B et al (2021).
J Taibah Univ Med Sci.
DOI:
10.1016/j.jtumed.2021.08.009
PubMed:
35592805

Euphorbia hirta Leaf Ethanol Extract Suppresses TNF-α/IFN-γ-Induced Inflammatory Response via Down-Regulating JNK or STAT1/3 Pathways in Human Keratinocytes.

Immunology
Gil TY et al (2022).
Life (Basel).
DOI:
10.3390/life12040589
PubMed:
35455080

Assessing a Medicinally Important Common Indian Weed Growing in the Arsenic-Affected Areas of West Bengal, India, Considering Its Impact on Human Health.

Mukherjee S et al (2022).
Appl Biochem Biotechnol.
DOI:
10.1007/s12010-021-03754-y
PubMed:
35286592

Phytochemicals of Euphorbia hirta L. and Their Inhibitory Potential Against SARS-CoV-2 Main Protease.

Summary

Scientists investigated the potential of a medicinal plant, used in Asia to treat respiratory disorders, to inhibit the SARS-CoV-2 main protease, a drug target for COVID-19. They used phytochemical mining and virtual screening to assess the potential of 298 phytochemicals for therapeutic use against COVID-19. They found 170 phytochemicals to have comparable or better binding properties for the SARS-CoV-2 Mpro target than known inhibitors. The study reaffirms the potential of the plant and its phytochemicals for COVID-19 treatment and highlights the utility of phytochemical mining and virtual screening in drug discovery.

COVID-19Phytochemistry
Cayona R and Creencia E (2022).
Front Mol Biosci.
DOI:
10.3389/fmolb.2021.801401
PubMed:
35187071

The complete chloroplast genome of Euphorbia hirta (Euphorbiaceae), a commonly used medicinal plant in China.

Genetics
Zhang Y et al (2021).
Mitochondrial DNA B Resour.
DOI:
10.1080/23802359.2021.1945506
PubMed:
34250241

Euphorbia.

Review
(2021).
PubMed:
30000943

Potential Use of Euphorbia hirta for Dengue: A Systematic Review of Scientific Evidence.

Review
Perera SD, Jayawardena UA and Jayasinghe CD (2018).
J Trop Med.
DOI:
10.1155/2018/2048530
PubMed:
29849664