Ficus carica

Common Names: common fig, edible fig

Ethnobotanical Studies

Studies

Coordination between water relations strategy and carbon investment in leaf and stem in six fruit tree species.

Piña I et al (2024).
Funct Plant Biol.
PubMed:
39222466

First Report and Molecular Characterization of Umbra-like Virus on Ficus carica Caprifig Trees in Crimea.

Motsar E et al (2024).
Plants (Basel).
PubMed:
39204698

New Insights Concerning Phytophotodermatitis Induced by Phototoxic Plants.

Review
Grosu Dumitrescu C et al (2024).
Life (Basel).
PubMed:
39202761

The synergistic effect of Ficus carica nanoparticles and Praziquantel on mice infected by Schistosoma mansoni cercariae.

El-Attar NA, El-Sawi MR and El-Shabasy EA (2024).
Sci Rep.
PubMed:
39147839

Functions, accumulation, and biosynthesis of important secondary metabolites in the fig tree (Ficus carica).

Review
Wang Y et al (2024).
Front Plant Sci.
PubMed:
39022605

Ficus carica L. (Fig) promotes nerve regeneration in a mouse model of sciatic nerve crush.

Sugita S et al (2024).
FEBS Open Bio.
PubMed:
38942739

Physicochemistry, Nutritional, and Therapeutic Potential of Ficus carica - A Promising Nutraceutical.

Review
Fazel MF et al (2024).
Drug Des Devel Ther.
PubMed:
38831870

Dynamic response of allelopathic potency of Taxus cuspidata Sieb. et Zucc. mediated by allelochemicals in Ficus carica Linn. root exudates.

Li Q et al (2024).
Sci Total Environ.
PubMed:
38823714

Biological activities of fig latex -loaded cellulose acetate/poly(ethylene oxide) nanofiber for potential therapeutics: Anticancer and antioxidant material.

Summary

Fig latex encapsulated in CA/PEO nanofiber scaffold effectively targets cancer cells with minimal harm to normal cells, demonstrating promising potential as a safer alternative to traditional chemotherapy.

El Fawal G, Sobhy SE and Hafez EE (2024).
Int J Biol Macromol.
PubMed:
38750845

Micropropagation and Genetic Fidelity of Fegra Fig (Ficus palmata Forssk.) and Grafting Compatibility of the Regenerated Plants with Ficus carica.

Al-Aizari AA et al (2024).
Plants (Basel).
PubMed:
38732493

Antioxidant Activity and Effectiveness of Fig Extract in Counteracting Carbon Tetrachloride-Induced Oxidative Damage in Rats.

Kebal L et al (2024).
Molecules.
PubMed:
38731494

Natural Sources of Therapeutic Agents Used in Skin Conditions.

Review
Dinu M et al (2024).
Life (Basel).
PubMed:
38672762

First Report of Rust Caused by Phakopsora nishidana on Creeping Fig, Ficus pumila, in South Africa.

Visser B, Boshoff WHP and Pretorius ZA (2024).
Plant Dis.
PubMed:
38625689

Fungal Species Causing Canker and Wilt of Ficus carica and Evidence of their Association with Bark Beetles in Italy.

Gusella G et al (2024).
Plant Dis.
PubMed:
38468134

Combined application of high pressure and ultrasound in fig paste: effect on bioactive and volatile compounds.

Meza-Velázquez JA et al (2023).
Food Sci Biotechnol.
PubMed:
38440688

Revelation of the discrepancy of volatile compounds in fig (Ficus carica) via gas chromatography ion-mobility spectrometry.

Liu X et al (2024).
Food Sci Nutr.
PubMed:
38370055

In planta expression of specific single chain fragment antibody (scFv) against nucleocapsid protein of fig mosaic virus (FMV).

Jahandideh M et al (2024).
J Virol Methods.
PubMed:
38368949

Ozone alters the chemical signal required for plant - insect pollination: The case of the Mediterranean fig tree and its specific pollinator.

Dubuisson C et al (2024).
Sci Total Environ.
PubMed:
38354792

Deep eutectic solvent (DES)-assisted extraction of pectin from Ficus carica Linn. peel: optimization, partial structure characterization, functional and antioxidant activities.

Liu H et al (2024).
J Sci Food Agric.
PubMed:
38297410

Aloe vera/Chitosan-Based Edible Film with Enhanced Antioxidant, Antimicrobial, Thermal, and Barrier Properties for Sustainable Food Preservation.

Summary

Scientists investigated the film-forming abilities of gel and chitosan combination for edible food packaging. The films improved the rheological, antioxidant, and thermal properties. Coating fruits with the films reduced microbial growth during storage, suggesting they can preserve fresh products effectively.

Kaur N et al (2024).
Polymers (Basel).
PubMed:
38257041

A Polysaccharide from Ficus carica L. Exerts Immunomodulatory Activity in Both In Vitro and In Vivo Experimental Models.

Ye L et al (2024).
Foods.
PubMed:
38254496

Understanding the Lost: Reconstruction of the Garden Design of Villa Peretti Montalto (Rome, Italy) for Urban Valorization.

Bartoli F et al (2023).
Plants (Basel).
PubMed:
38202385

Elucidating the structural, catalytic, and antibacterial traits of Ficus carica and Azadirachta indica leaf extract-mediated synthesis of the Ag/CuO/rGO nanocomposite.

Fayyaz Z et al (2024).
Microsc Res Tech.
PubMed:
38174385

Advancing understanding of Ficus carica: a comprehensive genomic analysis reveals evolutionary patterns and metabolic pathway insights.

Bao Y et al (2023).
Front Plant Sci.
PubMed:
38155853

Regulatory Effect of Ficus carica Latex on Cell Cycle Progression in Human Papillomavirus-Positive Cervical Cancer Cell Lines: Insights from Gene Expression Analysis.

Summary

Fig latex affects gene expression in cervical cancer cell lines, influencing pathways related to cancer development and progression. This suggests a potential novel therapeutic approach for HPV-related cervical cancer.

Cakir MO et al (2023).
Pharmaceuticals (Basel).
PubMed:
38139849

The Natural Ficus carica L. (fig) Extract as an Effective Prophylactic Antibacterial Agent for Inflammation-Related Infections.

Kim J and Lee D (2023).
Life (Basel).
PubMed:
38137957

Bioactive compound composition and cellular antioxidant activity of fig (Ficus carica L.).

Summary

Fig fruit and leaf phytochemicals were extracted using ultrasound, and their chemical compositions were analyzed. The findings can help determine the health benefits of figs, aiding in the development of functional foods.

Yang Q et al (2023).
J Sci Food Agric.
PubMed:
38115189

X-rays irradiation maintains redox homeostasis and regulates energy metabolism of fresh figs (Ficus carica L. Siluhongyu).

Wang C et al (2023).
Food Chem.
PubMed:
38039865

Lipidomic profiling reveals phenotypic diversity and nutritional benefits in Ficus carica L. (Fig.) seed cultivars.

Irchad A et al (2023).
Front Plant Sci.
PubMed:
38023854

Evaluation of a Fish Gelatin-Based Edible Film Incorporated with Ficus carica L. Leaf Extract as Active Packaging.

Fauzan HR, Ningrum A and Supriyadi S (2023).
Gels.
PubMed:
37999008

Exploring the pharmacological versatility of ficus carica: Modulating classical immunometabolism and beyond.

Saghazadeh A et al (2023).
Pharmacol Res.
PubMed:
37995897

Ficus carica polysaccharide extraction via ultrasound-assisted technique: Structure characterization, antioxidant, hypoglycemic and immunomodulatory activities.

Summary

Researchers optimized ultrasound-assisted extraction to isolate FCPS, a water-soluble polysaccharide from Ficus carica fruits. FCPS showed antioxidant activity, improved insulin resistance, and activated immune response, indicating its potential as an antioxidant source and functional food.

Wang W et al (2023).
Ultrason Sonochem.
PubMed:
37956509

Virtual screening, pharmacokinetics & MD simulation study of active phytoconstituents of Ficus Carica Linn. against PPAR-γ in diabetes mellitus.

Summary

This study evaluated bioactive compounds from a small tree against PPAR-γ, a target for diabetes management. Quercetin-3-o-rutinoside and other compounds showed potential as anti-diabetic agents and may act as PPAR-γ agonists.

Deshpande N S, Dwivedi PSR and Revanasiddappa BC (2023).
J Biomol Struct Dyn.
PubMed:
37948295

Diurnal decline in photosynthesis and stomatal conductance in several tropical species.

Suwannarut W, Vialet-Chabrand S and Kaiser E (2023).
Front Plant Sci.
PubMed:
37941668

Ficus carica Latex Modulates Immunity-Linked Gene Expression in Human Papillomavirus Positive Cervical Cancer Cell Lines: Evidence from RNA Seq Transcriptome Analysis.

Summary

Fig latex has potential therapeutic properties against HPV-positive cervical cancer, enhancing the expression of genes involved in immune surveillance and antigen presentation. This could aid in the clearance of early-stage cancer and contribute to the development of safer treatment modalities.

Cakir MO et al (2023).
Int J Mol Sci.
PubMed:
37686451

A surface multiple imprinting layers membrane with well-oriented recognition sites for selective separation of chlorogenic acid from Ficus carica L.

Luo Z et al (2023).
Food Chem.
PubMed:
37683463

In Vitro and In Vivo Anti-Psoriasis Activity of Ficus carica Fruit Extracts via JAK-STAT Modulation.

Lee JH and Lee MY (2023).
Life (Basel).
PubMed:
37629529

The Phenolic Composition and Antioxidant Properties of Figs (Ficus carica L.) Grown in the Black Sea Region.

Summary

This study analyzed the phenolic composition and antioxidant properties of different varieties of fig fruits. The dark purple species had the highest total polyphenol content and total antioxidant capacity, while the purple species had the highest flavonoid content and DPPH radical scavenging activity.

Bayrak Ç et al (2023).
Plant Foods Hum Nutr.
PubMed:
37605067

The Potential Roles of Ficus carica Extract in the Management of COVID-19 Viral Infections: A Computer-Aided Drug Design Study.

Summary

Researchers sought alternative methods to traditional drug discovery due to its high costs, time constraints, and low success rates. This could lead to safer, more effective therapies while saving resources.

Hamed M et al (2023).
Curr Comput Aided Drug Des.
PubMed:
37594095

Fig Tree-Induced Phytophotodermatitis: A Case Report on the Perils of a Hobby.

Pinto AR, Machado Cunha I and Rebelo Gomes E (2023).
Cureus.
PubMed:
37581161

In silico study on antidiabetic and antioxidant activity of bioactive compounds in Ficus carica L.

Summary

Study investigated the inhibitory potential of 10 phytochemicals on amylase enzymes through molecular simulations. Results could inform the development of diabetes treatments.

Raman APS et al (2023).
J Biomol Struct Dyn.
PubMed:
37545143

Evaluation of bioactive compounds from Ficus carica L. leaf extracts via high-performance thin-layer chromatography combined with effect-directed analysis.

Agatonovic-Kustrin S et al (2023).
J Chromatogr A.
PubMed:
37541060

Antibacterial and Antibiofilm Activity of Ficus carica-Mediated Calcium Oxide (CaONPs) Phyto-Nanoparticles.

Khan AU et al (2023).
Molecules.
PubMed:
37513425

First report of Ceratocystis ficicola causing wilt disease on common fig (Ficus carica) in Italy.

Habib W et al (2023).
Plant Dis.
PubMed:
37408125

Metabolomics and genetics of reproductive bud development in Ficus carica var. sativa (edible fig) and in Ficus carica var. caprificus (caprifig): similarities and differences.

Marcotuli I et al (2023).
Front Plant Sci.
PubMed:
37360723

Polygalacturonase gene family analysis identifies FcPG12 as a key player in fig (Ficus carica L.) fruit softening.

Wang Y et al (2023).
BMC Plant Biol.
PubMed:
37316788

Synthesis and Bioactivity of Isoflavones from Ficus carica and Some Non-Natural Analogues.

Nchiozem-Ngnitedem VA et al (2023).
J Nat Prod.
PubMed:
37253120

The inhibitory potential of chemical constituents of Ficus carica targeting interleukin-6 (IL-6) mediated inflammation.

Mansoor HUH, Ahmed A and Rasool F (2023).
Cell Biochem Funct.
PubMed:
37222443

Keeping Healthy in Your Skin-Plants and Fungi Used by Indigenous Himalayan Communities to Treat Dermatological Ailments.

Haq SM et al (2023).
Plants (Basel).
PubMed:
37050200

First Identification of Fig Virus A and Fig Virus B in Ficus carica in Italy.

Amoia SS, Chiumenti M and Minafra A (2023).
Plants (Basel).
PubMed:
37050129

Chemical Constituents and Antidiabetic Activity of Dichloromethane Extract from Ficus carica Leaves.

Lin L and Zhang Y (2023).
Diabetes Metab Syndr Obes.
PubMed:
37041932

Purification and characterization of a serine protease from the fruit of Ficus carica cultivar Masui Dauphine.

Tokonami M et al (2023).
Biosci Biotechnol Biochem.
PubMed:
37037773

Floral scent of the Mediterranean fig tree: significant inter-varietal difference but strong conservation of the signal responsible for pollinator attraction.

Cao L et al (2023).
Sci Rep.
PubMed:
37024518

Cubic nanoparticles as potential carriers for a natural anticancer drug: development, in vitro and in vivo characterization.

Abdou R et al (2023).
Drug Deliv Transl Res.
PubMed:
37010791

Influence of environmental conditions on the production of nutraceuticals in Italian edible plant landraces.

De Rossi S et al (2023).
Food Res Int.
PubMed:
36869496

Ficus carica (Linn.) Leaf and Bud Extracts and Their Combination Attenuates Type-1 Diabetes and Its Complications via the Inhibition of Oxidative Stress.

El Ghouizi A et al (2023).
Foods.
PubMed:
36832834

Industrial Application and Health Prospective of Fig (Ficus carica) By-Products.

Review
Rasool IFU et al (2023).
Molecules.
PubMed:
36770628

Latex derived from Ficus carica L. inhibited the growth of NSCLC by regulating the caspase/gasdermin/AKT signaling pathway.

Baohong L et al (2023).
Food Funct.
PubMed:
36762489

Genome-wide in silico identification of glutathione S-transferase (GST) gene family members in fig (Ficus carica L.) and expression characteristics during fruit color development.

Review Genetics
Liu L et al (2023).
PeerJ.
PubMed:
36718451

Food packaging composite film based on chitosan, natural kaolinite clay, and Ficus. carica leaves extract for fresh-cut apple slices preservation.

El Mouzahim M et al (2023).
Int J Biol Macromol.
PubMed:
36716844

"Phytophotodermatitis as a clinical problem and as a therapeutic option: case report and review of the literature".

Mansilla-Polo M et al (2023).
Photodiagnosis Photodyn Ther.
PubMed:
36693457

A comprehensive perspective of traditional Arabic or Islamic medicinal plants as an adjuvant therapy against COVID-19.

Summary

This study explores the potential of Traditional Arabic or Islamic medicinal plants as adjuvant therapy for COVID-19. Six medicinal plants with antiviral and immunomodulatory properties were studied, suggesting they could be used to control symptoms and possibly lead to a COVID-19 medicinal synthesis. However, further evaluation is advised before using these plants as therapy. No evidence-based medication to combat COVID-19 currently exists despite multiple vaccine strategies.

Review COVID-19
Ahmed SI et al (2023).
Saudi J Biol Sci.
PubMed:
36684115

Effect of Kaolin clay and Ficus carica mediated silver nanoparticles on chitosan food packaging film for fresh apple slice preservation.

Mouzahim ME et al (2023).
Food Chem.
PubMed:
36652798

Comparison of Two Varieties Fig (Peggy Red and Green) Peel Extracts by Liquid Chromatography-Tandem Mass Spectrometry Analysis and for Neuroprotective Efficacy in Caenorhabditis elegans.

Summary

Researchers analyzed the ethanol extract of Peggy Red and Green fig peel through LC-MS/MS to determine its phytochemical components and neuroprotective effects. They found 50 compounds including phenols, flavonoids, and anthocyanins with antioxidant properties. Peggy Red had higher antioxidant activity and was able to reduce toxicity in Alzheimer's transgenic CL4176 by decreasing the aggregation of amyloid-beta and increasing antioxidant enzyme activities. The results suggest the potential of Peggy Red peel extract as a new drug source against AD.

Liu S, Xiao C and Wang F (2023).
J Med Food.
PubMed:
36595373

Bioengineered synthesis of phytochemical-adorned green silver oxide (Ag(2)O) nanoparticles via Mentha pulegium and Ficus carica extracts with high antioxidant, antibacterial, and antifungal activities.

Shahzad Shirazi M et al (2022).
Sci Rep.
PubMed:
36513776

Establishment of Arthrobotrys flagrans as biocontrol agent against the root pathogenic nematode Xiphinema index.

Wernet V and Fischer R (2023).
Environ Microbiol.
PubMed:
36354014

A systematic review on potential anticancer activities of Ficus carica L. with focus on cellular and molecular mechanisms.

Review Cancer
Morovati MR et al (2022).
Phytomedicine.
PubMed:
35952577

A novel breathable package system to improve the fresh fig (Ficus carica L. 'Dottato') shelf life.

Attilio M et al (2023).
J Sci Food Agric.
PubMed:
35751906

Ingenious application of ethylenediaminetetraacetic acid disodium to improve the extraction yield of psoralen in fig (Ficus carica L.) leaves.

Zhao C et al (2023).
Nat Prod Res.
PubMed:
34546825

Comparative anticancer activities of Ficus carica and Ficus salicifolia latex in MDA-MB-231 cells.

AlGhalban FM, Khan AA and Khattak MNK (2021).
Saudi J Biol Sci.
PubMed:
34121859

Ficus carica assisted green synthesis of metal nanoparticles: A mini review.

Review
Patil SP et al (2020).
Biotechnol Rep (Amst).
PubMed:
34094890

Commodity risk assessment of Ficus carica plants from Israel.

EFSA Panel on Plant Health (PLH) et al (2021).
EFSA J.
PubMed:
33519991

Characterization of proteases activities in Ficus carica cultivars.

Nishimura K et al (2020).
J Food Sci.
PubMed:
32027028

Enzymes inhibitors from natural sources with antidiabetic activity: A review.

Review Diabetes
Alam F et al (2019).
Phytother Res.
PubMed:
30417583

The effects of Ficus carica on the activity of enzymes related to metabolic syndrome.

Mopuri R et al (2018).
J Food Drug Anal.
PubMed:
29389556

Ficus carica L. (Moraceae): an ancient source of food and health.

Review
Barolo MI, Ruiz Mostacero N and López SN (2014).
Food Chem.
PubMed:
24996314

1-Cyclo-hexyl-6,7-dimeth-oxy-1,4-di-hydro-naphthalene.

Chen SY et al (2014).
Acta Crystallogr Sect E Struct Rep Online.
PubMed:
24940252

Ficus carica L. (Moraceae): Phytochemistry, Traditional Uses and Biological Activities.

Mawa S, Husain K and Jantan I (2013).
Evid Based Complement Alternat Med.
PubMed:
24159359