Foeniculum vulgare

Common Names: sweet fennel

Ethnobotanical Studies

Studies

[Antimicrobial in vitro effects of eight essential oils on Pasteurella multocida and Mannheimia haemolytica from nasopharyngeal swab samples of fattening calves].

Summary

Study tested antibacterial effects of 8 essential oils on P. multocida and M. haemolytica isolates. Lemongrass oil most potent. Different effects seen with agar diffusion and microdilution methods. Important for potential phytotherapeutic treatments.

Salzmann BA et al (2024).
Schweiz Arch Tierheilkd.
PubMed:
39225505

Identification of a novel recombinant polerovirus and other emergent viruses and tombusvirus-like associated RNA species associated with carrot motley dwarf disease in the United States.

Erickson A et al (2024).
Front Microbiol.
PubMed:
39132135

The Mediterranean Species Calendula officinalis and Foeniculum vulgare as Valuable Source of Bioactive Compounds.

Review
Vella FM, Pignone D and Laratta B (2024).
Molecules.
PubMed:
39124999

Determination of Antioxidant, Cytotoxicity, and Anti-human Lung Cancer Properties of Silver Nanoparticles Green-Formulated by Foeniculum vulgare Extract Combined with Radiotherapy.

Summary

Researchers synthesized silver nanoparticles using fennel leaf extract and tested them with radiotherapy on lung cancer cells. The nanoparticles showed potential for fighting cancer. This study may lead to new treatments for lung cancer.

Wu Q et al (2024).
Biol Trace Elem Res.
PubMed:
39107456

Bioinspired chitosan based functionalization of biomedical implant surfaces for enhanced hemocompatibility, antioxidation and anticoagulation potential: an in silico and in vitro study.

Hassan S et al (2024).
RSC Adv.
PubMed:
38952927

The positive impact of honeybee activity on fennel crop production and sustainability.

Ali MA, Al-Farga A and Seddik MA (2024).
Sci Rep.
PubMed:
38937513

Plant beneficial traits of endophytic bacteria associated with fennel (Foeniculum vulgare Mill.).

Shurigin V et al (2024).
AIMS Microbiol.
PubMed:
38919721

Preparation and characterization of fennel (Foeniculum vulgare miller) essential oil/hydroxypropyl-β-cyclodextrin inclusion complex and its application for chilled pork preservation.

Song Q et al (2024).
Food Chem.
PubMed:
38865819

First Report of White Mold Caused by Sclerotinia sclerotiorum on Hymenocallis glauca in Mexico.

Terrones-Salgado J et al (2024).
Plant Dis.
PubMed:
38853333

Antibacterial, antibiofilm, and chemical profiles of Ammi visnaga L. and Foeniculum vulgare mill. Essential oils, and ADMET, molecular docking investigation of essential oils major components.

Khammassi M et al (2024).
Fitoterapia.
PubMed:
38838824

Identification and expression profiling of microRNAs in leaf tissues of Foeniculum vulgare Mill. under salinity stress.

Bravo-Vázquez LA et al (2024).
Plant Signal Behav.
PubMed:
38825852

Enhancing the nitric oxide inhibitory activity using a combination of plant essential oils and mixture design approach.

Marrelli M et al (2024).
Heliyon.
PubMed:
38803904

(-)-Fenchone Prevents Cysteamine-Induced Duodenal Ulcers and Accelerates Healing Promoting Re-Epithelialization of Gastric Ulcers in Rats via Antioxidant and Immunomodulatory Mechanisms.

Araruna MEC et al (2024).
Pharmaceuticals (Basel).
PubMed:
38794211

Cananga odorata L., Illicium verum, and Foeniculum vulgare essential oils impair the reproduction of the cattle tick Rhipicephalus microplus (Acari: Ixodidae).

Gonçalves RRP et al (2024).
Vet Parasitol.
PubMed:
38781832

Evaluating the effects of various ethanolic medicinal plant extracts on metastatic breast cancer proliferation, invasion, and expression of a novel potential drug target; CD82 metastatic suppressor protein, and on in vivo angiogenesis using the ex ovo yolk sac membrane (YSM) assay.

Summary

Researchers screened plant extracts for anti-metastatic properties in breast cancer cells by targeting CD82 expression. Results show potential for multi-system treatment to inhibit metastasis and improve patient outcomes.

Loggenberg S, Twilley D and Lall N (2024).
J Cancer Res Clin Oncol.
PubMed:
38753184

The protective effects of some herbs on mitigating HFD-induced obesity via enhancing biochemical indicators and fertility in female rats.

Summary

Study showed that diets enriched with fennel and coriander reduced obesity risks and improved fertility in obese female rats better than chia seeds and hibiscus. Consider plant-based diets for obesity prevention.

Abdoon ASS et al (2024).
Heliyon.
PubMed:
38726161

Chemical composition and biological activities of essential oils of seven Cultivated Apiaceae species.

Önder S et al (2024).
Sci Rep.
PubMed:
38698117

Co-application of biochar and selenium nanoparticles improves yield and modifies fatty acid profile and essential oil composition of fennel (Foeniculum vulgare Mill.) under cadmium toxicity.

Jahantigh M et al (2024).
Environ Sci Pollut Res Int.
PubMed:
38630399

Efficacy of fennel (Foeniculum vulgare) and anise (Pimpinella anisum) essential oils as anaesthesics in common carp (Cyprinus carpio L. 1758).

Metin S et al (2024).
Fish Physiol Biochem.
PubMed:
38630160

Ethnobotanical survey on herbal remedies for the management of type 2 diabetes in the Casablanca-Settat region, Morocco.

Summary

Study investigates the use of medicinal plants in traditional medicine in Casablanca-Settat region for managing type 2 diabetes. Essential for addressing public health challenge in Morocco.

Arraji M et al (2024).
BMC Complement Med Ther.
PubMed:
38622669

Long-Term Monitoring of the Traditional Knowledge of Plant Species Used for Culinary Purposes in the Valencia Region, South-Eastern Spain.

Belda A et al (2024).
Plants (Basel).
PubMed:
38592810

Polycystic Ovary Syndrome and Oxidative Stress. Natural Treatments.

Summary

Review discusses treatments focusing on oxidative stress in PCOS, crucial for reproductive and metabolic abnormalities. Natural compounds like KH, Foeniculum Vulgare, and minerals show promise in managing symptoms. Important for improving PCOS management strategies.

Motta AB et al (2024).
Curr Med Chem.
PubMed:
38549535

Exploring Trachyspermum ammi and Foeniculum vulgare in Hydroponic System and Compare its Chemical Constituents with Soil-Based Method: A Prospective in Agriculture.

Debnath S and Sharma A (2024).
Recent Pat Biotechnol.
PubMed:
38528667

Chitosan nanoparticles loaded with Foeniculum vulgare extract regulate retrieval of sensory and motor functions in mice.

Bajaber MA et al (2024).
Heliyon.
PubMed:
38352784

Dietary encapsulated fennel seed (Foeniculum vulgare Mill.) essential oil supplementation improves performance, modifies the intestinal microflora, morphology, and transcriptome profile of broiler chickens.

İpçak HH, Alçiçek A and Denli M (2024).
J Anim Sci.
PubMed:
38330242

Antifungal Activity of Thirty Essential Oils to Control Pathogenic Fungi of Postharvest Decay.

Summary

This study evaluated the inhibitory effects of 30 essential oils (EOs) on the growth of fungal pathogens in crops. The EOs showed promising results in completely inhibiting the growth of some fungi and significantly reducing the growth of others. More research is needed to confirm these findings in real-life settings.

Allagui MB, Moumni M and Romanazzi G (2023).
Antibiotics (Basel).
PubMed:
38247587

Profiling the chemical properties of Foeniculum vulgare Mill. and its flavonoids through comprehensive LC-MS/MS to evaluate their anti-motion sickness effect.

Zhao L et al (2023).
Fitoterapia.
PubMed:
38168571

Chemoprofiling and antimicrobial activity of medicinal herbs used in the treatment of inflammatory bowel disease.

Summary

This study evaluated the antimicrobial activity of five herbs used to treat inflammatory bowel disease (IBD) in Saudi Arabia. The herbs showed good activity against E. coli and S. aureus, suggesting their potential as natural remedies for IBD.

Alshahrani A, Ali A and Abdelwahab SF (2023).
Cell Mol Biol (Noisy-le-grand).
PubMed:
38158691

Removal of Methyl Red from Aqueous Solution Using Biochar Derived from Fennel Seeds.

Paluch D et al (2023).
Molecules.
PubMed:
38067516

An extract from the frass of swallowtail butterfly (Papilio machaon) larvae inhibits HCT116 colon cancer cell proliferation but not other cancer cell types.

Summary

This study investigates the chemical components of insect frass from Papilio machaon larvae fed on different plants and their biological activity. It also explores the expression of CYP genes in the larvae's midgut to understand their metabolic system. Care about this because it may reveal potential natural medicines and provide insights into insect metabolism.

Nakano M et al (2023).
BMC Genomics.
PubMed:
38049715

Anethole mitigates H(2) O(2) -induced inflammation in HIG-82 synoviocytes by suppressing the aquaporin 1 expression and activating the protein kinase A pathway.

Huang TL et al (2023).
Environ Toxicol.
PubMed:
37987213

Application of bio-organic amendments improves soil quality and yield of fennel (Foeniculum vulgare Mill.) plants in saline calcareous soil.

Al-Elwany OAAI et al (2023).
Sci Rep.
PubMed:
37963917

Bio-Monitoring of Metal(loid)s Pollution in Dry Riverbeds Affected by Mining Activity.

Cuevas J et al (2023).
Plants (Basel).
PubMed:
37960131

Improved antioxidant activities of spice require enrichment of distinct yet closely-related metabolic pathways.

Summary

The researchers used a reverse association strategy to identify target metabolic pathways for increased production of phytochemicals. They found enrichment of isoprenoids and fatty acids biosynthetic pathways, indicating a need for enrichment of specific metabolic pathways to achieve improved antioxidant effects in spices.

Gandhi S, Saha MR and Dey P (2023).
Heliyon.
PubMed:
37920519

Safety and efficacy of feed additives consisting of essential oils from the fruit and stems of Foeniculum vulgare Mill. ssp. vulgare: Bitter fennel oil for use in all animal species and sweet fennel oil for use in dogs and cats (FEFANA asbl).

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) et al (2023).
EFSA J.
PubMed:
37908453

Describing the Pollen Content in the Gastrointestinal Tract of Vespa velutina Larvae.

Diéguez-Antón A et al (2023).
Animals (Basel).
PubMed:
37835643

Exploring therapeutic targets and drug candidates for obesity: a combined network pharmacology, bioinformatics approach.

Summary

This study investigates the potential of native Saudi Arabian plants for treating obesity by identifying phytochemicals that regulate metabolism and reduce fat accumulation, offering natural solutions for obesity treatment.

Aloufi B et al (2023).
J Biomol Struct Dyn.
PubMed:
37811763

Use of medicinal plants during COVID-19 pandemic in Brazil.

Summary

Study finds 40.2% of participants in a Brazilian city use medicinal plants, primarily for anxiety. Females, non-whites, and lower-educated with higher income and comorbidities were more likely to use. No reported use for treating COVID-19.

da Silva AM et al (2023).
Sci Rep.
PubMed:
37783716

Lower dose of plant substance more effective in repelling Rhyzopertha dominica F . (Coleoptera, Bostrichidae) and Sitophilus granarius L. (Coleoptera, Dryophthoridae).

Izdebska AM et al (2023).
Ann Agric Environ Med.
PubMed:
37772516

New Insights on Primary and Secondary Metabolite Contents of Seven Italian Wild Food Plants with Medicinal Applications: A Comparative Study.

Monari S et al (2023).
Plants (Basel).
PubMed:
37765345

Attenuation of CFA-induced chronic inflammation by a bicyclic monoterpene fenchone targeting inducible nitric oxide, prostaglandins, C-reactive protein and urea.

Summary

Fenchone, found in certain plants, has strong anti-inflammatory properties. In a rat model, it reduced pro-inflammatory markers and improved symptoms of chronic joint inflammation, suggesting therapeutic potential for inflammatory disorders.

Nawaz S et al (2023).
Inflammopharmacology.
PubMed:
37689616

Fennel affects porcine ovarian cell functions: The interrelationships with the environmental contaminant benzene.

Summary

Fennel promotes cell growth and hormone release, while benzene disrupts these processes. However, fennel cannot reverse the effects of benzene on ovarian cells.

Sirotkin AV et al (2023).
Res Vet Sci.
PubMed:
37657392

Bio-organic fertilizers promote yield, chemical composition, and antioxidant and antimicrobial activities of essential oil in fennel (Foeniculum vulgare) seeds.

Summary

The study found that using a combination of poultry manure, Lactobacillus plantarum, and Lactococcus lactis produced high-quality fennel seed essential oil with strong antimicrobial properties, benefiting industrial use.

Abdelbaky AS et al (2023).
Sci Rep.
PubMed:
37626070

Effect of Different Soil Treatments on Production and Chemical Composition of Essential Oils Extracted from Foeniculum vulgare Mill., Origanum vulgare L. and Thymus vulgaris L.

Raffo A et al (2023).
Plants (Basel).
PubMed:
37570990

Chemical Variability of the Essential Oils from Two Portuguese Apiaceae: Coriandrum sativum L. and Foeniculum vulgare Mill.

Machado AM et al (2023).
Plants (Basel).
PubMed:
37514362

Assessment of the Attitudes, Beliefs, and Potential Effects of Nutritional Phytoestrogenic Plant Consumption on Women's Health in Saudi Arabia.

Elagib H et al (2023).
Cureus.
PubMed:
37496541

Seaweed extract and arbuscular mycorrhiza co-application affect the growth responses and essential oil composition of Foeniculum vulgare L.

Rasouli F et al (2023).
Sci Rep.
PubMed:
37488427

First Report on the Synergistic Interaction between Essential Oils against the Pinewood Nematode Bursaphelenchus xylophilus.

Faria JMS et al (2023).
Plants (Basel).
PubMed:
37446999

Extraction, characterization of polyphenols from certain medicinal plants and evaluation of their antioxidant, antitumor, antidiabetic, antimicrobial properties, and potential use in human nutrition.

Summary

Dietary medicinal plants are highly valuable in alternative medicine, with disease-preventing and healing properties that can improve overall well-being and reduce disease risk, revolutionizing healthcare.

Mueed A et al (2023).
Front Nutr.
PubMed:
37415912

Incredible Combination of Lifestyle Modification and Herbal Remedies for Polycystic Ovarian Syndrome Management.

Summary

Researchers reviewed the use of yoga and herbal remedies for polycystic ovarian syndrome (PCOS), a common hormonal disorder. These alternative therapies can help improve symptoms and quality of life, offering a holistic approach to PCOS management. Further research is needed to validate these findings.

Balkrishna A et al (2023).
Evid Based Complement Alternat Med.
PubMed:
37383339

Behavioral and Electrophysiological Study on Eight Japanese Papilio Species with Five Hostplant Volatiles and Linalool.

Inoue TA et al (2023).
J Chem Ecol.
PubMed:
37378686

Essential oils and extracts of plants as biocides against microorganisms isolated from the ruins of the Roman city of Conímbriga (Portugal).

Mateus DMR et al (2023).
Environ Sci Pollut Res Int.
PubMed:
37326731

Effect of Essential Oils of Apiaceae, Lamiaceae, Lauraceae, Myrtaceae, and Rutaceae Family Plants on Growth, Biofilm Formation, and Quorum Sensing in Chromobacterium violaceum, Pseudomonas aeruginosa, and Enterococcus faecalis.

D'Aquila P et al (2023).
Microorganisms.
PubMed:
37317124

Alfalfa, Cabbage, Beet and Fennel Microgreens in Floating Hydroponics-Perspective Nutritious Food?

Fabek Uher S et al (2023).
Plants (Basel).
PubMed:
37299078

The effects of purslane (Portulaca oleracea) and fennel (Foeniculum vulgare Mill) hydroalcoholic extracts on the functional parameters of human spermatozoa after vitrification.

Torkamanpari M et al (2023).
Clin Exp Reprod Med.
PubMed:
37258100

Validation of γ-radiation and their effect on phenolic compounds, antioxidant activity, and microbial load of fennel (Foeniculum vulgare) seeds and cinnamon (Cinnamomum verum) sticks.

Ahmed SM and Hassan AB (2023).
Food Sci Nutr.
PubMed:
37051350

Cholinesterase Inhibitors from an Endophytic Fungus Aspergillus niveus Fv-er401: Metabolomics, Isolation and Molecular Docking.

Hamed AA et al (2023).
Molecules.
PubMed:
36985531

Nanosuspension of Foeniculum Vulgare Promotes Accelerated Sensory and Motor Function Recovery after Sciatic Nerve Injury.

Bajaber MA et al (2023).
Metabolites.
PubMed:
36984831

Evaluation of the Anti-Metastatic Effect of Foeniculum Vulgare on the Protein Expression of HSP 70 & 90 in Balb/c Mice with 4t1 Model of Breast Cancer.

Sadegh Roudbari L et al (2023).
Asian Pac J Cancer Prev.
PubMed:
36974535

Enhanced antimicrobial and antioxidant properties of Nano chitosan and pectin based biodegradable active packaging films incorporated with fennel (Foeniculum vulgare) essential oil and potato (Solanum tuberosum) peel extracts.

Sadadekar AS et al (2023).
J Food Sci Technol.
PubMed:
36908350

In Vivo Antiphytoviral and Aphid Repellency Activity of Essential Oils and Hydrosols from Mentha suaveolens and Foeniculum vulgare to Control Zucchini Yellow Mosaic Virus and Its Vector Aphis gossypii.

Taglienti A et al (2023).
Plants (Basel).
PubMed:
36903936

Essential Oils from Apiaceae, Asteraceae, Cupressaceae and Lamiaceae Families Grown in Serbia: Comparative Chemical Profiling with In Vitro Antioxidant Activity.

Gladikostić N et al (2023).
Plants (Basel).
PubMed:
36840093

Nephroprotective Effect of Fennel (Foeniculum vulgare) Seeds and Their Sprouts on CCl(4)-Induced Nephrotoxicity and Oxidative Stress in Rats.

Barakat H et al (2023).
Antioxidants (Basel).
PubMed:
36829884

Exploring fennel (Foeniculum vulgare): Composition, functional properties, potential health benefits, and safety.

Rafieian F et al (2023).
Crit Rev Food Sci Nutr.
PubMed:
36803269

In utero and postnatal exposure to Foeniculum vulgare and Linum usitatissimum seed extracts: modifications of key enzymes involved in epigenetic regulation and estrogen receptors expression in the offspring's ovaries of NMRI mice.

Pourjafari F et al (2023).
BMC Complement Med Ther.
PubMed:
36788561

A Comparative UHPLC-Q-Trap-MS/MS-Based Metabolomics Analysis to Distinguish Foeniculum vulgare Cultivars' Antioxidant Extracts.

Crescenzi MA et al (2023).
Molecules.
PubMed:
36677955

Safety and efficacy of a feed additive consisting of a tincture derived from the fruit of Foeniculum vulgare Mill. ssp. vulgare var. dulce (sweet fennel tincture) for use in all animal species (FEFANA asbl).

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) et al (2023).
EFSA J.
PubMed:
36620493

Synergic effects of some plant-derived essential oils and Iranian isolates of entomopathogenic fungus Metarhizium anisopliae Sorokin to control Acanthoscelides obtectus (Say) (Coleoptera: Chrysomelidae).

Lak F et al (2022).
Front Plant Sci.
PubMed:
36570934

Elevated CO(2) concentration induces changes in plant growth, transcriptome, and antioxidant activity in fennel (Foeniculum vulgare Mill.).

Jo NY et al (2022).
Front Plant Sci.
PubMed:
36570891

Phytochemical Profile of Foeniculum vulgare Subsp. piperitum Essential Oils and Evaluation of Acaricidal Efficacy against Varroa destructor in Apis mellifera by In Vitro and Semi-Field Fumigation Tests.

Bava R et al (2022).
Vet Sci.
PubMed:
36548845

Characterization of fennel germplasm for physiological persistence and drought recovery: Association with biochemical properties.

Hosseini ES et al (2023).
Plant Physiol Biochem.
PubMed:
36516537

Antigiardial Activity of Foeniculum vulgare Hexane Extract and Some of Its Constituents.

Domínguez-Vigil IG et al (2022).
Plants (Basel).
PubMed:
36079594

Binary Synergistic Combinations of Lavender and Fennel Essential Oils with Amoxicillin.

Karadağ AE et al (2023).
Planta Med.
PubMed:
35789993

Foeniculum vulgare Miller, a New Chemotype from Montenegro.

Božović M et al (2021).
Plants (Basel).
PubMed:
35009044

Correlation between insulin-like growth factor 1 gene expression and fennel (Foeniculum vulgare) seed powder consumption in muscle of sheep.

Shahsavari M et al (2023).
Anim Biotechnol.
PubMed:
34783639

Fennel (Foeniculum vulgare Miller) for the management of menopausal women's health: A systematic review and meta-analysis.

Meta-Analysis
Lee HW et al (2021).
Complement Ther Clin Pract.
PubMed:
33725577

Foeniculum vulgare seed extract exerts anti-cancer effects on hepatocellular carcinoma.

Ke W et al (2021).
Food Funct.
PubMed:
33502415

Foeniculum vulgare as Valuable Plant in Management of Women's Health.

Review
Mahboubi M et al (2019).
J Menopausal Med.
PubMed:
31080784

Fennel.

Review
(2022).
PubMed:
30000852

Herbal Medicine for Oligomenorrhea and Amenorrhea: A Systematic Review of Ancient and Conventional Medicine.

Review
Moini Jazani A et al (2018).
Biomed Res Int.
PubMed:
29744355

A review of effective herbal medicines in controlling menopausal symptoms.

Review
Kargozar R, Azizi H and Salari R (2017).
Electron Physician.
PubMed:
29403626

Anti-Aging Potential of Phytoextract Loaded-Pharmaceutical Creams for Human Skin Cell Longetivity.

Review
Jadoon S et al (2015).
Oxid Med Cell Longev.
PubMed:
26448818

Foeniculum vulgare Mill: a review of its botany, phytochemistry, pharmacology, contemporary application, and toxicology.

Badgujar SB, Patel VV and Bandivdekar AH (2014).
Biomed Res Int.
PubMed:
25162032