Gladiolus dalenii

Ethnobotanical Studies

Aswa River catchment, northern Uganda

Uses: cough; debility; poison

DOI:: 10.1186/s13002-023-00620-5
PubMed:: 37884931

Studies

In vitro study on efficacy of PHELA, an African traditional drug against SARS-CoV-2.

Summary

Researchers investigated an herbal combination of four African medicinal plants known as PHELA as a potential therapy for COVID-19. In vitro testing found that PHELA inhibited > 90% of SARS-CoV-2 and SARS-CoV infection as well as close to 100% of MERS-CoV infection. In silico docking studies showed strong binding energy interactions between compounds in PHELA and SARS-CoV-2 proteins. PHELA has potential as a COVID-19 therapeutic.

COVID-19

Matsabisa MG et al (2022).; Sci Rep.
DOI:: 10.1038/s41598-022-13599-y
PubMed:: 35718800

Medicinal plants species used by herbalists in the treatment of snakebite envenomation in Uganda.

Okot DF et al (2020).; Trop Med Health.
DOI:: 10.1186/s41182-020-00229-4
PubMed:: 32518500

Effects of Gladiolus dalenii on the Stress-Induced Behavioral, Neurochemical, and Reproductive Changes in Rats.

Fotsing D et al (2017).; Front Pharmacol.
DOI:: 10.3389/fphar.2017.00685
PubMed:: 29021759

Gladiolus dalenii lyophilisate reverses scopolamine-induced amnesia and reduces oxidative stress in rat brain.

Immunology Neuroscience

Ngoupaye GT et al (2017).; Biomed Pharmacother.
DOI:: 10.1016/j.biopha.2017.04.061
PubMed:: 28463798

Antidepressant properties of aqueous macerate from Gladiolus dalenii corms.

Neuroscience

Ngoupaye GT et al (2013).; Afr J Tradit Complement Altern Med.
PubMed:: 24653553

Antidepressant-like effects of the aqueous macerate of the bulb of Gladiolus dalenii Van Geel (Iridaceae) in a rat model of epilepsy-associated depression.

Neuroscience

Ngoupaye GT, Bum EN and Daniels WM (2013).; BMC Complement Altern Med.
DOI:: 10.1186/1472-6882-13-272
PubMed:: 24138845

The anticonvulsant and sedative effects of Gladiolus dalenii extracts in mice.

Ngoupaye GT et al (2013).; Epilepsy Behav.
DOI:: 10.1016/j.yebeh.2013.06.014
PubMed:: 23891766

Antifungal activity of crude extracts of gladiolus dalenii van geel (iridaceae).

Antimicrobial

Odhiambo JA et al (2009).; Afr J Tradit Complement Altern Med.
PubMed:: 21304613