Common Names: English ivy
Alpha-Hederin from ivy or black seed plants shows promise in treating non-small cell lung cancer by inhibiting mTOR, disrupting autophagy, and causing autophagic damage.
Researchers identified an endophytic fungus from Hedera helix L. with potent antimicrobial activity. The isolated compound, spiculisporic acid, showed promising activity against drug-resistant strains. Further investigation could lead to the development of new antibiotics.
Hederagenin, a compound from Hedera helix, has anti-cancer, anti-inflammatory, anti-depressant, and anti-fibrosis properties. This study shows that hederagenin suppresses ovarian cancer cell growth, induces apoptosis, alters mitochondrial morphology, and modulates the protein Drp1 to inhibit cancer progression.
L. leaf extract exhibits antioxidant and antibacterial properties with potential for treating infections, requiring further study to identify active compounds and mechanisms.
COVID-19 can cause neurological complications, including anxiety, depression, MAD, and irreversible dementia, which can harm respiratory, circulatory, and heart function. Clinical trials suggest that phytotherapy, using natural plant materials like valeranon and apigenin, can aid these conditions. The study presents plant materials and their active compounds that can reduce post-COVID-19 complications, particularly those impacting the nervous system.
The current self-management recommendations for COVID-19 involve rest, hydration, and the use of NSAIDs for high fever. Many patients may also use herbal medicines.
Hedera helix (ivy) is commonly used to treat asthma, but its effects on lung histopathology are unclear. This study found that oral administration of Hedera helix reduced goblet cell counts and thickness of basement membrane in asthmatic airways, but dexamethasone was more effective in improving all histopathologic parameters except basement membrane thickness.