Heliopsis helianthoides

Common Names: smooth oxeye

Ethnobotanical Studies

Studies

Integrative analysis of transcriptome and metabolome provides insights into the mechanisms of leaf variegation in Heliopsis helianthoides.

Genetics
Qin H et al (2024).
BMC Plant Biol.
DOI:
10.1186/s12870-024-05450-5
PubMed:
39085772

Pathogenic Isolates of Rhodococcus fascians from New Hosts in the United States.

Putnam ML and Miller M (2006).
Plant Dis.
DOI:
10.1094/PD-90-0526C
PubMed:
30786616

Evaluation of lignans from Heliopsis helianthoides var. scabra for their potential antimetastatic effects in the brain.

Summary

Researchers isolated six compounds from the roots of a plant called Heliopsis helianthoides var. scabra and tested their effects on brain tumor metastasis formation. Two of the compounds, helioxanthin (3) and (7E)-7,8-dehydroheliobuphthalmin (4), inhibited the migration of melanoma and brain endothelial cells. Compound 3 also reduced the adhesion of melanoma cells to the brain endothelium and enhanced the barrier function of the blood-brain barrier. These findings suggest that compounds 3 and 4 have the potential to interfere with different steps of brain metastasis formation and to enhance the barrier function of cerebral endothelial cells.

NeurosciencePhytochemistry
Hajdu Z et al (2014).
J Nat Prod.
DOI:
10.1021/np500508y
PubMed:
25479041

Identification of endocannabinoid system-modulating N-alkylamides from Heliopsis helianthoides var. scabra and Lepidium meyenii.

Hajdu Z et al (2014).
J Nat Prod.
DOI:
10.1021/np500292g
PubMed:
24972328

Prairie forb response to timing of vole herbivory.

Sullivan AT and Howe HF (2009).
Ecology.
PubMed:
19537554

Planting densities and bird and rodent absence affect size distributions of four dicots in synthetic tallgrass communities.

Martínez-Garza C et al (2004).
Oecologia.
PubMed:
14986097