Hemidesmus indicus

Ethnobotanical Studies

Studies

From nature's bounty to drug discovery: Leveraging phytochemicals and molecular approaches to combat multi-drug-resistant (MDR) tuberculosis.

Review
Nalam SM et al (2024).
Indian J Tuberc.
DOI:
10.1016/j.ijtb.2023.08.007
PubMed:
39067943

Optimization of ultrasound-assisted extraction of bioactive chemicals from Hemidesmus indicus (L.) R.Br. using response surface methodology and adaptive neuro-fuzzy inference system.

Vellur S et al (2023).
Food Sci Biotechnol.
DOI:
10.1007/s10068-023-01351-9
PubMed:
38222910

Evaluation of the Efficacy of a Neem Extract-Based Herbal Ointment, Herbal Antioxidant, and Propolis on Oxidative Stress Related to Oral Ulcers: An Interventional Animal Study.

Immunology
Patel A et al (2023).
Cureus.
DOI:
10.7759/cureus.48542
PubMed:
38073963

Antibacterial activity of 2-hydroxy-4-methoxybenzaldehyde and its possible mechanism against Staphylococcus aureus.

Arunachalam K et al (2023).
J Appl Microbiol.
DOI:
10.1093/jambio/lxad144
PubMed:
37422440

An In Silico Molecular Modelling-Based Prediction of Potential Keap1 Inhibitors from Hemidesmus indicus (L.) R.Br. against Oxidative-Stress-Induced Diseases.

Vellur S et al (2023).
Molecules.
DOI:
10.3390/molecules28114541
PubMed:
37299017

HR-LCMS and evaluation of anti-diabetic activity of Hemidesmus indicus (anantmool): Kinetic study, and molecular modelling approach.

Summary

This study identified Hemidesmus indicus as a potential source for antidiabetic medications. The herb showed high extractive yield and inhibited carbohydrate hydrolytic enzymes. Molecular modeling techniques confirmed its potential as an inhibitor of alpha-amylase and alpha-glucosidase, suggesting it could be developed as a lead for type-2 diabetes medications.

Diabetes
Kumari S et al (2023).
Comput Biol Chem.
DOI:
10.1016/j.compbiolchem.2023.107896
PubMed:
37263051

Photosynthesis of silver nanoparticles embedded paper for sensing mercury presence in environmental water.

Dharshini KS et al (2023).
Chemosphere.
DOI:
10.1016/j.chemosphere.2023.138610
PubMed:
37028721

Elicitor mediated enhancement of shoot biomass and lupeol production in Hemidesmus indicus (L.) R. Br. ex. Schult. and Tylophora indica (Burm. F.) Merrill using yeast extract and salicylic acid.

Pathak AR et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2022.2119388
PubMed:
36059233

Methanolic extract of Hemidesmus indicus root augments the antibacterial and antibiofilm activity of amoxicillin and clindamycin against methicillin-resistant Staphylococcus aureus of bovine origin.

Sannat C et al (2022).
Lett Appl Microbiol.
DOI:
10.1111/lam.13825
PubMed:
36053759

Analysis of the chemical composition of root essential oil from Indian sarsaparilla (Hemidesmus indicus) and its application as an ecofriendly insecticide and pharmacological agent.

Phytochemistry
Narayanankutty A et al (2021).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2021.08.028
PubMed:
34867028

Box-Behnken design avenue for development and validation of high-performance thin-layer chromatography method for estimation of rutin in Hemidesmus indicus.

Phytochemistry
Shrivastava S and Daharwal SJ (2022).
Biomed Chromatogr.
DOI:
10.1002/bmc.5236
PubMed:
34469592

Exploration of plant products and phytochemicals against aflatoxin toxicity in broiler chicken production: Present status.

Review
Umaya SR, Vijayalakshmi YC and Sejian V (2021).
Toxicon.
DOI:
10.1016/j.toxicon.2021.06.017
PubMed:
34228958

Exploring the endogenous potential of Hemidesmus indicus against breast cancer using in silico studies and quantification of 2-hydroxy-4-methoxy benzaldehyde through RP-HPLC.

Cancer
Bansod AA et al (2021).
3 Biotech.
DOI:
10.1007/s13205-021-02768-x
PubMed:
33968579

Repression of Polyol Pathway Activity by Hemidesmus indicus var. pubescens R.Br. Linn Root Extract, an Aldose Reductase Inhibitor: An In Silico and Ex Vivo Study.

Haroon HB et al (2021).
Nat Prod Bioprospect.
DOI:
10.1007/s13659-020-00290-w
PubMed:
33284412

Hemidesmus indicus L. Br.: critical assessment of in vitro biotechnological advancements and perspectives.

Review
Nandy S et al (2020).
Appl Microbiol Biotechnol.
DOI:
10.1007/s00253-020-10851-1
PubMed:
32910270

Indian sarsaparilla, Hemidesmus indicus (L.) R. Br. ex Schult: tissue culture studies.

Review
Kher MM et al (2020).
Appl Microbiol Biotechnol.
DOI:
10.1007/s00253-020-10714-9
PubMed:
32535696

Hemidesmus indicus induces apoptosis via proteasome inhibition and generation of reactive oxygen species.

Turrini E et al (2019).
Sci Rep.
DOI:
10.1038/s41598-019-43609-5
PubMed:
31076590

Antiosteoporotic effect of Hemidesmus indicus Linn. on ovariectomised rats.

Desai S et al (2017).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2017.01.031
PubMed:
28119100

In vitro anti-angiogenic effects of Hemidesmus indicus in hypoxic and normoxic conditions.

Turrini E et al (2015).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2014.12.010
PubMed:
25560668

Hemidesmus indicus induces apoptosis as well as differentiation in a human promyelocytic leukemic cell line.

Ferruzzi L et al (2013).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2013.02.009
PubMed:
23500881

The bioactive and therapeutic potential of Hemidesmus indicus R. Br. (Indian Sarsaparilla) root.

Review
Das S and Bisht SS (2013).
Phytother Res.
DOI:
10.1002/ptr.4788
PubMed:
22887725

Natriuretic and saluretic effects of Hemidesmus indicus R. Br. root extracts in rats.

Gadge NB and Jalalpure SS (2011).
Indian J Pharmacol.
DOI:
10.4103/0253-7613.89833
PubMed:
22144781