Common Names: common hop, common hops, hops
Researchers found that hop bitter acids from hops improved lipid and carbohydrate metabolism in obese mice, stabilizing glycemia levels and weight gain while enhancing antioxidant capacity and brain health. This suggests potential benefits for managing obesity-related complications and cognitive decline.
Ag-based nanoparticles were synthesized using plant extracts on cotton fabric, showing excellent antifungal and antibacterial activity. Stable and non-toxic, they are promising for medical applications.
Quantified 60 bitter compounds in hops using LC-MS/MS method. Found differences in dry-hopped vs. non-dry-hopped beer profiles. Shows how brewing techniques affect beer bitterness. Important for hop-forward beer production.
Hop extract shows strong antimicrobial activity against oral bacteria, including MRSA. Contains flavonoids and phloroglucides that increase antibiotic efficiency. Promising for oral care and potentiating traditional antimicrobials.
Plumbagin and xanthohumol combo shows strong anticancer activity in pancreatic cancer models by affecting BCL2 levels, leading to increased survival in mice. Potential new treatment option.
Researchers synthesized iron oxide nanoparticles using spent hops extracts, evaluated their antioxidant properties, and found that modification with DMSO extract improved antibacterial activity against Gram-positive bacteria. Important for potential applications in antimicrobial and biomedical fields.
Xanthohumol (XN), a compound in hops, has health benefits. A study found that XN does not significantly change gut microbiota composition, but does affect individual taxa and bile acid metabolism in an enterotype-dependent way. Individual responses to XN vary, suggesting personalized effects on gut health.
Humulus lupulus extracts contain various molecules with antimicrobial, antioxidant, and anti-inflammatory properties, such as polyphenols, α-acids, β-acids, and hydrocarbons. Understanding these components helps harness the plant's medicinal benefits.
This study explored compounds from hops as potential antiviral therapies against the Oropouche virus. The beta acids showed the strongest inhibitory potential in post-treatment assays, and xanthohumol showed high affinity for the virus. Lys92 and Arg33 had the highest affinity with the protein.
Xanthohumol derivatives were tested for their ability to kill cancer cells. Compound 8 was the most effective, inhibiting cell migration and inducing apoptosis. It could potentially be a promising anti-cancer treatment.
Compounds from the hop plant, including xanthohumol, have strong antiviral effects. XN specifically shows promise in inhibiting the main protease of SARS-CoV-2. This could be valuable for developing potential treatments against COVID-19.
Scientists developed a mixture of plant extracts that showed potential in preventing and treating viral respiratory diseases. The mixture exhibited antioxidant, cytoprotective, immunomodulating, and antiviral properties. Activation of Nrf2 may contribute to its cytoprotective effects. Further studies are needed to explore its nutraceutical applications.
Study finds differences in antioxidant activity of hop extracts from different genotypes, no correlation with chemical components. Compound interactions have greater influence on activity than individual compounds.
Xanthohumol (XN) is a compound that can potentially fight breast and lung cancer. This study explores its effects using a unique 3D cell culture technique.
Licorice root extract, specifically Glycyrrhiza inflata (GI), shows promise in preventing breast cancer in high-risk postmenopausal women. This natural product has high aromatase inhibition potency, which is important for suppressing estrogen and preventing cancer growth. Phytoestrogens found in licorice, such as liquiritigenin, also inhibit aromatase and reduce uterine growth in vivo. Liquiritigenin further decreases RNA translation, protein biosynthesis, and metabolism in breast tissue, and slows down cell proliferation. These findings suggest that liquiritigenin could be an effective preventive measure for breast cancer in high-risk postmenopausal women.
Research has revealed potential herbal medicines for treating mild mood disorders, but with unclear active components. The microbiota-gut-brain axis offers new avenues for treatment and prevention of mood disorders.
COVID-19 can cause neurological complications, including anxiety, depression, MAD, and irreversible dementia, which can harm respiratory, circulatory, and heart function. Clinical trials suggest that phytotherapy, using natural plant materials like valeranon and apigenin, can aid these conditions. The study presents plant materials and their active compounds that can reduce post-COVID-19 complications, particularly those impacting the nervous system.