Hyoscyamus niger

Common Names: black henbane

Ethnobotanical Studies

Clinical Trials

The effect of propolis plus Hyoscyamus niger L. methanolic extract on clinical symptoms in patients with acute respiratory syndrome suspected to COVID-19: A clinical trial.

A study found that a syrup with propolis and Hyoscyamus niger L. extract reduced COVID-19 symptoms like cough, shortness of breath, and sore throat, but not nausea and vomiting.

Kosari M et al (2021).
Phytother Res.
DOI:
10.1002/ptr.7116
PubMed:
33860587

Studies

Elemental Profiling of Common Anti-diabetic Medicinal Plants of Swat and Peshawar Districts of Khyber Pakhtunkhwa (KPK) Province of Pakistan: An Investigation Using PIXE and ICP-OES.

Summary

Study analyzed elemental composition of 16 anti-diabetic plants using PIXE and ICP-OES. Plants contain essential elements such as Zn and Se crucial for glucose metabolism and insulin function. Results support their use in diabetes management.

Diabetes
Zubair A et al (2024).
Biol Trace Elem Res.
DOI:
10.1007/s12011-024-04305-2
PubMed:
39037503

The influence of propolis plus Hyoscyamus niger L. against COVID-19: A phase II, multicenter, placebo-controlled, randomized trial.

Summary

Propolis syrup with Hyoscyamus niger L. extract reduced COVID-19 symptoms, improved oxygen levels, and shortened hospital stays in 140 patients, suggesting it as a potential treatment.

COVID-19
Kosari M et al (2023).
Phytother Res.
DOI:
10.1002/ptr.8047
PubMed:
37992760

Simultaneous quantification of hyoscyamine and scopolamine using HPLC-DAD in four Solanaceae: Hyoscyamus niger, Datura stramonium, Atropa belladonna and Mandragora officinarum.

Piatti D et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2269595
PubMed:
37830795

Evaluation of medicinal plants using laser-induced breakdown spectroscopy (LIBS) combined with chemometric techniques.

Nouman Khan M et al (2023).
Lasers Med Sci.
DOI:
10.1007/s10103-023-03805-2
PubMed:
37365431

Break-induced replication is the primary recombination pathway in plant somatic hybrid mitochondria: a model for mt-HGT.

Gandini CL et al (2023).
J Exp Bot.
DOI:
pii: erad104. 10.1093/jxb/erad104
PubMed:
36928121

Rapid Detection and Determination of Scopolamine in the Leaf Extract of Black Henbane (Hyoscyamus niger L.) Plants Using a Novel Nanosensor.

Mousavizadeh FS et al (2022).
J AOAC Int.
DOI:
10.1093/jaoacint/qsac061
PubMed:
35951765

A novel spray bioreactor for the proliferation of plant callus; Hyoscyamus niger and Arnebia pulchra.

Goojgi ST et al (2022).
Biotechnol Lett.
DOI:
10.1007/s10529-022-03235-0
PubMed:
35182262

Clove Buds Essential Oil: The Impact of Grinding on the Chemical Composition and Its Biological Activities Involved in Consumer's Health Security.

Phytochemistry
Ben Hassine D et al (2021).
Biomed Res Int.
DOI:
10.1155/2021/9940591
PubMed:
34381841

Treatment of opium addiction in persian medicine: A review study.

Summary

Opium addiction is a major public health issue in Iran, where it is the most commonly used illicit drug. This study examined treatment strategies from the perspective of Persian medicine. The search was conducted in Persian medicine books and databases using keywords related to opioids and opium since 2000 AD. Gradual and delayed reduction of opium levels, combined with appropriate spice replacements, was suggested for quitting. The study highlights the potential of traditional medicine in addressing modern public health problems.

Review Neuroscience
Kamali M et al (2021).
J Educ Health Promot.
DOI:
10.4103/jehp.jehp_5_21
PubMed:
34222532

Nixing the nightshades: Traditional knowledge of intoxicating members of the Solanaceae among hallucinogenic plant and mushroom users in Slovenia.

Fatur K and Kreft S (2021).
PLoS One.
DOI:
10.1371/journal.pone.0247688
PubMed:
33617573

Induced mutation breeding for qualitative and quantitative traits and varietal development in medicinal and aromatic crops at CSIR-CIMAP, Lucknow (India): past and recent accomplishment.

Review
Lal RK, Chanotiya CS and Gupta P (2020).
Int J Radiat Biol.
DOI:
10.1080/09553002.2020.1834161
PubMed:
33026919

Insecticidal Activity of Hyoscyamus niger L. on Lucilia sericata Causing Myiasis.

Küpeli Akkol E et al (2020).
Plants (Basel).
DOI:
10.3390/plants9050655
PubMed:
32455988

The Saga continues: Solanaceae May cast too much shade for effective berserking.

Blumenberg A and Horowitz Z (2020).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2019.112327
PubMed:
31639489

Metabolic Characterization of Hyoscyamus niger Ornithine Decarboxylase.

Zhao T et al (2019).
Front Plant Sci.
DOI:
10.3389/fpls.2019.00229
PubMed:
30873201

Forestalling the Epidemics of Parkinson's Disease Through Plant-Based Remedies.

Summary

This review examines six plants, three from European and Asian traditional medicinal systems, for their potential to treat Parkinson's disease. One of the plants (Datura stramonium) is commonly known for its poisonous effects, but all six plants contain compounds with potential neuroprotective and anti-neurodegenerative effects. Specifically, is known for its high antioxidant potential and neuroprotective/anti-apoptotic activity. Complementary and alternative therapies (CAT) are gaining popularity for the treatment of chronic diseases like Parkinson's, which imposes a heavy burden among individuals and economies worldwide.

Review Neuroscience
Banjari I et al (2018).
Front Nutr.
DOI:
10.3389/fnut.2018.00095
PubMed:
30425989

Metabolic characterization of Hyoscyamus niger root-specific putrescine N-methyltransferase.

Geng C et al (2018).
Plant Physiol Biochem.
DOI:
10.1016/j.plaphy.2018.03.001
PubMed:
29549757

Clinical outcomes in children with hyoscyamus niger intoxication not receiving physostigmine therapy.

Doneray H, Orbak Z and Karakelleoglu C (2007).
Eur J Emerg Med.
PubMed:
17968201

Withanolides from hyoscyamus niger seeds.

Ma CY, Williams ID and Che CT (1999).
J Nat Prod.
PubMed:
10543915

Hyoscyamus niger (henbane).

Haas LF et al (1995).
J Neurol Neurosurg Psychiatry.
PubMed:
7629522

Henbane chewing.

Sands JM and Sands R (1976).
Med J Aust.
PubMed:
979798