GeoBotanical: Hypericum scabrum

1.

Effect of Hypericum thymbrifolium BOISS. ET NOE, Hypericum scabrum L. and Eryngium creticum LAM. plant extracts on Leishmania major, Leishmania tropica and Leishmania infantum/donovani strains and their cytotoxic potential.

Ozpinar H et al (2024).; Trop Biomed.
DOI:: 10.47665/tb.41.1.005
PubMed:: 38852132

2.

In vitro antimicrobial and antibiofilm screening of eighteen Iranian medicinal plants.

Summary

Iranian medicinal plants show promising antimicrobial properties, a potential low-cost solution to drug-resistant pathogens with minimal side effects. Crucial for developing new antibiotics.

Antimicrobial

Hamidi M et al (2024).; BMC Complement Med Ther.
DOI:: 10.1186/s12906-024-04437-x
PubMed:: 38549139

3.

Determination of essential oil and biological activities of Hypericum ternatum Poulter and H. scabrum L. species collected from different localities: is H. scabrum an alternative to multifunctional species ST JOHN'S WORT (H. perforatum)?

Summary

The study analyzed the essential oil compositions of certain plant species and their biological activities. The essential oils showed potential in antioxidant, cytotoxic, enzyme inhibitory, and cosmetic/pharmaceutical applications.

Phytochemistry

Akdeniz M et al (2022).; Turk J Chem.
DOI:: 10.55730/1300-0527.3494
PubMed:: 37621346

4.

Three New Xanthones from Hypericum scabrum and Their Quorum Sensing Inhibitory Activities against Chromobacterium violaceum.

Teng LP et al (2022).; Molecules.
DOI:: 10.3390/molecules27175519
PubMed:: 36080284

5.

Bioactive polycyclic polyprenylated acylphloroglucinols from Hypericum scabrum.

Zhou ZB et al (2022).; Fitoterapia.
DOI:: 10.1016/j.fitote.2022.105249
PubMed:: 35798061

6.

Effects of Hypericum scabrum L. essential oil on wound healing in streptozotocin-induced diabetic rats.

Diabetes Phytochemistry

Ibaokurgil F, Yildirim BA and Yildirim S (2022).; Cutan Ocul Toxicol.
DOI:: 10.1080/15569527.2022.2052890
PubMed:: 35373654

7.

Anatomical and Phytochemical Characteristics of Different Parts of Hypericum scabrum L. Extracts, Essential Oils, and Their Antimicrobial Potential.

Antimicrobial Phytochemistry

Ergin KN et al (2022).; Molecules.
DOI:: 10.3390/molecules27041228
PubMed:: 35209017

8.

Antimicrobial Activity and Synergy Investigation of Hypericum scabrum Essential Oil with Antifungal Drugs.

Antimicrobial Phytochemistry

Fahed L et al (2021).; Molecules.
DOI:: 10.3390/molecules26216545
PubMed:: 34770954

9.

Structural Revision of Hyperibrin B and Hyperscabrones H and I by Biosynthetic Considerations, NMR Analysis, and Chemical Synthesis.

Phytochemistry

Wang X et al (2021).; J Nat Prod.
DOI:: 10.1021/acs.jnatprod.1c00458
PubMed:: 34236871

10.

Unusual derivatives from Hypericum scabrum.

Soroury S et al (2021).; Sci Rep.
DOI:: 10.1038/s41598-020-79305-y
PubMed:: 33446755

11.

Nine prenylated acylphloroglucinols with potential anti-depressive and hepatoprotective activities from Hypericum scabrum.

Ma J et al (2021).; Bioorg Chem.
DOI:: 10.1016/j.bioorg.2020.104529
PubMed:: 33339665

12.

Hypolipidemic effects of Hypericum Scabrum extract on the serum lipid profile and obesity in high-fat diet fed rats.

Obesity

Faraji N et al (2021).; Hum Antibodies.
DOI:: 10.3233/HAB-200430
PubMed:: 33136094

13.

Effects of Hypericum scabrum extract on dentate gyrus synaptic plasticity in high fat diet-fed rats.

Omidi G et al (2020).; J Physiol Sci.
DOI:: 10.1186/s12576-020-00747-0
PubMed:: 32209056

14.

Polyprenylated acylphloroglucinols from Hypericum scabrum.

Liu R et al (2017).; Phytochemistry.
DOI:: 10.1016/j.phytochem.2017.06.011
PubMed:: 28675829

15.

Polyisoprenylated benzoylphloroglucinol derivatives from Hypericum scabrum.

Gao W et al (2016).; Fitoterapia.
DOI:: 10.1016/j.fitote.2016.10.003
PubMed:: 27751884

16.

Polycyclic Polyprenylated Acylphloroglucinol Congeners from Hypericum scabrum.

Gao W et al (2016).; J Nat Prod.
DOI:: 10.1021/acs.jnatprod.5b01063
PubMed:: 27280968

17.

Cytotoxic Activity and Apoptosis Induction of Hypericum scabrum L.

Hamzeloo-Moghadam M, Khalaj A and Malekmohammadi M (2015).; Iran Red Crescent Med J.
DOI:: 10.5812/ircmj.19453
PubMed:: 26568855

Hypericum scabrum

Ethnobotanical Studies

Shahrekord, Iran

Studies