Ichnocarpus frutescens

Ethnobotanical Studies

Studies

Phytochemical profiling and evaluation of the antidiabetic potential of Ichnocarpus frutescens (Krishna Sariva): kinetic study, molecular modelling, and free energy approach.

Summary

This research explored antidiabetic properties of a natural herb using enzyme assay and computational approaches. The herb demonstrated promising inhibitory activity against diabetes-related enzymes, with compounds showing better binding energy than a standard drug. The study suggests that the herb could be used as a medication for type 2 diabetes.

DiabetesPhytochemistry
Kumari S, Saini R and Mishra A (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2248265
PubMed:
37615387

Evaluation of Wound Healing Activity (Excision Wound Model) of Ointment Prepared from Infusion Extract of Polyherbal Tea Bag Formulation in Diabetes-Induced Rats.

Diabetes
Quazi A et al (2022).
Evid Based Complement Alternat Med.
DOI:
10.1155/2022/1372199
PubMed:
35707477

In Vitro Alpha-Amylase Enzyme Assay of Hydroalcoholic Polyherbal Extract: Proof of Concept for the Development of Polyherbal Teabag Formulation for the Treatment of Diabetes.

Diabetes
Quazi A et al (2022).
Evid Based Complement Alternat Med.
DOI:
10.1155/2022/1577957
PubMed:
35600963

Antidiabetic potential of active fraction obtained from methanolic extract of Ichnocarpus frutescens: A possible herbal remedy.

Diabetes
Srujana M, Ramesh R and Nanjaiah LD (2018).
Indian J Pharmacol.
DOI:
10.4103/ijp.IJP_24_18
PubMed:
30636828

Ichnocarpus frutescens (L.) R. Br. root derived phyto-steroids defends inflammation and algesia by pulling down the pro-inflammatory and nociceptive pain mediators: An in-vitro and in-vivo appraisal.

ImmunologyPain
Das N et al (2018).
Steroids.
DOI:
10.1016/j.steroids.2018.09.005
PubMed:
30217788

Facile fabrication of eco-friendly nano-mosquitocides: Biophysical characterization and effectiveness on neglected tropical mosquito vectors.

Govindarajan M, Hoti SL and Benelli G (2016).
Enzyme Microb Technol.
DOI:
10.1016/j.enzmictec.2016.05.005
PubMed:
27866611

Ichnocarpus frutescens Ameliorates Experimentally Induced Convulsion in Rats.

Singh NK et al (2014).
Int Sch Res Notices.
DOI:
10.1155/2014/434179
PubMed:
27379268

Effect of active sub-fraction of Ichnocarpus frutescens (L.) R.Br. in the management of obesity.

Obesity
Saravanan M, Pandikumar P and Ignacimuthu S (2016).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2015.11.031
PubMed:
26602455

Polyphenol extract of ichnocarpus frutescens leaves modifies hyperglycemia in dexamethasone (dex) treated rats.

DiabetesPhytochemistry
Kumarappan C and Mandal SC (2014).
Indian J Physiol Pharmacol.
PubMed:
26215014

Anticancer activity of the roots of Ichnocarpus frutescens R. Br. and isolated triterpenes.

Cancer
Singh NK and Singh VP (2014).
Pak J Pharm Sci.
PubMed:
24374448

Effect of Ichnocarpus frutescens (L.) R.Br. hexane extract on preadipocytes viability and lipid accumulation in 3T3-L1 cells.

Saravanan M and Ignacimuthu S (2013).
Asian Pac J Trop Med.
DOI:
10.1016/S1995-7645(13)60039-5
PubMed:
23608374

Antimicrobial activities of Ichnocarpus frutescens (L.) R.Br. and Hemidesmus indicus R.Br. Roots.

Antimicrobial
Malathy NS and Sini S (2009).
Anc Sci Life.
PubMed:
22557326

Antihyperlipidemic activity of Ichnocarpus frutescens in triton WR-1339-induced and high-fat diet animals.

Saravanan M et al (2011).
Pharm Biol.
DOI:
10.3109/13880209.2011.565477
PubMed:
21591834

Antidiabetic activity of aqueous root extract of Ichnocarpus frutescens in streptozotocin-nicotinamide induced type-II diabetes in rats.

Diabetes
Barik R et al (2008).
Indian J Pharmacol.
DOI:
10.4103/0253-7613.40484
PubMed:
21264156