Incarvillea sinensis

Ethnobotanical Studies

Studies

Incarvine C and its analogues inhibit the formation of cell cytoskeleton by targeting Rac1.

Zhao P et al (2024).
Bioorg Chem.
DOI:
10.1016/j.bioorg.2024.107512
PubMed:
38833990

Shade Increased Seed Yield and Quality of Incarvillea sinensis var. przewalskii.

Wang Y et al (2023).
Plants (Basel).
DOI:
10.3390/plants12162934
PubMed:
37631146

Linking key dimensions of plant phenotypic diversity. A commentary on: 'Mating systems and life history'.

Pannell JR et al (2021).
Ann Bot.
DOI:
10.1093/aob/mcab023
PubMed:
33758904

Characterization of the chloroplast genome and its inference on the phylogenetic position of Incarvillea sinensis Lam. (Bignoniaceae).

Genetics
Wu X, Li H and Chen S (2021).
Mitochondrial DNA B Resour.
DOI:
10.1080/23802359.2020.1860722
PubMed:
33659649

Do annual and perennial populations of an insect-pollinated plant species differ in mating system?

Ma Y et al (2021).
Ann Bot.
DOI:
10.1093/aob/mcaa178
PubMed:
33035305

[Response of understory species distribution of Robinia pseudoacacia plantation to environmental factors in loess hilly region, China.].

Wu HF et al (2019).
Ying Yong Sheng Tai Xue Bao.
DOI:
10.13287/j.1001-9332.201911.002
PubMed:
31833676

Natural product incarvillateine aggravates epileptic seizures by inhibiting GABA(A) currents.

Summary

Incarvillateine is a natural compound known for its pain-relieving properties. However, researchers have discovered that it worsens epileptic seizures by inhibiting a type of receptor in the brain called γ-Aminobutyric acid type A (GABA). The researchers conducted experiments on frog eggs and hippocampal slices, and also injected incarvillateine into the brains of rats. They found that the compound inhibited GABA currents and synaptic transmissions, leading to an increase in epileptic activity. This study sheds light on the molecular effects of incarvillateine and its potential negative impact on patients with epilepsy.

Neuroscience
Bian X et al (2019).
Eur J Pharmacol.
DOI:
10.1016/j.ejphar.2019.172496
PubMed:
31242440

Gram Scale Syntheses of (-)-Incarvillateine and Its Analogs. Discovery of Potent Analgesics for Neuropathic Pain.

Pain
Huang B et al (2016).
J Med Chem.
DOI:
10.1021/acs.jmedchem.6b00132
PubMed:
27022999

Seasonal variation in the mating system of a selfing annual with large floral displays.

Yin G et al (2016).
Ann Bot.
DOI:
10.1093/aob/mcv186
PubMed:
26721904

Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis, and possible involvement of the adenosine system.

Phytochemistry
Wang ML et al (2015).
Sci Rep.
DOI:
10.1038/srep16107
PubMed:
26527075

Phylogeographic analysis reveals significant spatial genetic structure of Incarvillea sinensis as a product of mountain building.

Chen S et al (2012).
BMC Plant Biol.
PubMed:
22546007

Development of polymorphic microsatellite markers for Incarvillea sinensis (Bignoniaceae).

Yu HY et al (2011).
Am J Bot.
DOI:
10.3732/ajb.1100052
PubMed:
21821586

A novel macrocyclic spermine alkaloid from Incarvillea sinensis.

Phytochemistry
Chi YM et al (2007).
J Asian Nat Prod Res.
PubMed:
17454308

Pharmacological study on the novel antinociceptive agent, a novel monoterpene alkaloid from Incarvillea sinensis.

Phytochemistry
Chi YM et al (2005).
Biol Pharm Bull.
PubMed:
16204962

A monoterpene alkaloid from incarvillea sinensis.

Phytochemistry
Chi YM et al (2005).
Chem Pharm Bull (Tokyo).
PubMed:
16141592

Structure-antinociceptive activity studies of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis.

Phytochemistry
Nakamura M et al (2001).
Planta Med.
PubMed:
11301854