Kalanchoe pinnata

Common Names: cathedral bells

Ethnobotanical Studies

Studies

Kalanchoe pinnata (Lam.) Pers. Leaf ethanolic extract exerts selective anticancer activity through ROS-induced apoptotic cell death in human cancer cell lines.

Cancer
Faundes-Gandolfo N et al (2024).
BMC Complement Med Ther.
DOI:
10.1186/s12906-024-04570-7
PubMed:
39010075

Natural Immunomodulatory Agents as a Complementary Therapy for Poxviruses.

Summary

Researchers identified polyphenolics and isoquinoline alkaloids as potential antiviral agents against monkeypox virus by targeting viral elements. Natural extracts from traditional plants also show promise. Urgent molecular studies are needed to confirm their anti-poxvirus properties.

Review Immunology
Ali SI and Salama A (2024).
Adv Exp Med Biol.
DOI:
10.1007/978-3-031-57165-7_22
PubMed:
38801589

Antioxidant, Anti-inflammatory, and Antimicrobial Activity of the Kalanchoe pinnata and Piper longum Formulation Against Oral Pathogens.

Summary

Formulation of and shows strong antimicrobial activity against oral pathogens, antioxidants, and anti-inflammatory properties. Could be alternative to pharmaceuticals for oral health.

AntimicrobialImmunology
Anandan J and Shanmugam R (2024).
Cureus.
DOI:
10.7759/cureus.57824
PubMed:
38721202

Elucidating the anti-obesity potential of bioactive fractions of kalanchoe pinnata (lam.) leaves extract using a combination of in vitro, in vivo and in silico methods along with characterisation of lead compounds through an HPTLC ms-MS(n) analytical study.

Summary

Scientists isolated and tested anti-obesity fractions from leaves. Fraction F2 showed the most potential, reducing body weight and lipids in obese mice. It contains compounds with binding capability for proteins, suggesting a therapeutic strategy for obesity.

Obesity
Pratap Singh R and Pattnaik AK (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2344183
PubMed:
38656916

Exploring the therapeutic mechanism of potential phytocompounds from Kalanchoe pinnata in the treatment of diabetes mellitus by integrating network pharmacology, molecular docking and simulation approach.

Summary

Researchers studied the bioactive compounds in a medicinal plant for potential anti-type-2 diabetes effects. Identified key targets and pathways through various analyses, showing promise for novel anti-diabetic treatments.

Diabetes
Halayal RY et al (2024).
Saudi Pharm J.
DOI:
10.1016/j.jsps.2024.102026
PubMed:
38550331

Repurposing of Bryophyllum pinnatum for dysmenorrhea treatment: a systematic scoping review and case series.

Zurfluh L et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1292919
PubMed:
38130407

BDMediLeaves: A leaf images dataset for Bangladeshi medicinal plants identification.

Islam S et al (2023).
Data Brief.
DOI:
10.1016/j.dib.2023.109488
PubMed:
37636130

Bioactive Ingredients in K. pinnata Extract and Synergistic Effects of Combined K. pinnata and Metformin Preparations on Antioxidant Activities in Diabetic and Non-Diabetic Skeletal Muscle Cells.

DiabetesImmunology
Ramon P et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24076211
PubMed:
37047182

Corrigendum: Bryophyllum pinnatum compounds inhibit oxytocin-induced signaling pathways in human myometrial cells.

Summary

Unfortunately, this abstract does not provide any information about the study or its findings as it only corrects the DOI of a previously published article. Without the original abstract or article, it is impossible to provide a summary for the general user.

Neuroscience
Santos S et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1141346
PubMed:
36843937

Potential of Kalanchoe pinnata as a Cancer Treatment Adjuvant and an Epigenetic Regulator.

Review Cancer
Hernández-Caballero ME et al (2022).
Molecules.
DOI:
10.3390/molecules27196425
PubMed:
36234962

The Genus Kalanchoe (Crassulaceae) in Ecuador: From Gardens to the Wild.

Vargas A et al (2022).
Plants (Basel).
DOI:
10.3390/plants11131746
PubMed:
35807700

Comparative and Evolutionary Analyses on the Complete Plastomes of Five Kalanchoe Horticultural Plants.

Tian X et al (2021).
Front Plant Sci.
DOI:
10.3389/fpls.2021.705874
PubMed:
34512691

Effects of Bryophyllum pinnatum Administration on Wistar Rat Pregnancy: Biochemical and Histological Aspects.

Hosomi JK et al (2022).
Complement Med Res.
DOI:
10.1159/000517508
PubMed:
34237738

Fungal Chitosan-Derived Biomaterials Modified with Kalanchoe pinnata as Potential Hemostatic Agents-Development and Characterization.

Radwan-Pragłowska J et al (2021).
Polymers (Basel).
DOI:
10.3390/polym13081300
PubMed:
33921117

Effect of Combined K. pinnata and Metformin Preparation on Inflammatory Cytokines in Normal and Diabetic Skeletal Muscle Cells.

Immunology
Ramon P, Sparks J and Omoruyi F (2021).
J Med Food.
DOI:
10.1089/jmf.2020.0078
PubMed:
33179996

Genotoxicity studies with an ethanolic extract of Kalanchoe pinnata leaves.

Saravanan V, Murugan SS and Kumaravel TS (2020).
Mutat Res Genet Toxicol Environ Mutagen.
DOI:
10.1016/j.mrgentox.2020.503229
PubMed:
32928369

Wound healing cream formulated with Kalanchoe pinnata major flavonoid is as effective as the aqueous leaf extract cream in a rat model of excisional wound.

Coutinho MAS et al (2021).
Nat Prod Res.
DOI:
10.1080/14786419.2020.1817012
PubMed:
32924590

Cytotoxic and genotoxic effects of Kalanchoe pinnata (Lam.) Pers. fresh leaf juice in the cultured human blood lymphocytes.

Immunology
Bhavsar S and Chandel D (2022).
Drug Chem Toxicol.
DOI:
10.1080/01480545.2019.1696814
PubMed:
31791148

Local anti-inflammatory activity: Topical formulation containing Kalanchoe brasiliensis and Kalanchoe pinnata leaf aqueous extract.

Immunology
de Araújo ERD et al (2019).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2019.108721
PubMed:
30856538

Stomatal response to blue light in crassulacean acid metabolism plants Kalanchoe pinnata and Kalanchoe daigremontiana.

Gotoh E et al (2019).
J Exp Bot.
DOI:
10.1093/jxb/ery450
PubMed:
30576518

In Vitro Antilithiatic Potential of Kalanchoe pinnata, Emblica officinalis, Bambusa nutans, and Cynodon dactylon.

Sohgaura AK, Bigoniya P and Shrivastava B (2018).
J Pharm Bioallied Sci.
DOI:
10.4103/JPBS.JPBS_18_18
PubMed:
29962797

Gastroprotective and Antioxidant Activity of Kalanchoe brasiliensis and Kalanchoe pinnata Leaf Juices against Indomethacin and Ethanol-Induced Gastric Lesions in Rats.

Gastroenterology
de Araújo ERD et al (2018).
Int J Mol Sci.
DOI:
10.3390/ijms19051265
PubMed:
29695040