Lagerstroemia speciosa

Common Names: pride of India

Ethnobotanical Studies

Clinical Trials

Effect of Banaba (Lagerstroemia speciosa) on Metabolic Syndrome, Insulin Sensitivity, and Insulin Secretion.

López-Murillo LD et al (2022).
J Med Food.
DOI:
10.1089/jmf.2021.0039
PubMed:
34726501

Studies

The Efficacy and Safety of DLBS3233, A Combined Bioactive Fraction of Cinnamomum burmanii and Lagerstroemia speciosa Plants on The Endocrine-Metabolic Profile of Women with Polycystic Ovary Syndrome: A Randomized Clinical Trial.

Summary

DLBS3233 from speciosa used for type-2-diabetes in PCOS women. Improves insulin sensitivity, metabolic and reproductive health. Consider for PCOS treatment.

Endocrinology
Hestiantoro A et al (2024).
Int J Fertil Steril.
DOI:
10.22074/ijfs.2023.551350.1283
PubMed:
39033369

Applying Network Pharmacology and Molecular Docking in the Screening for Molecular Mechanisms of Ampalaya (Momordica charantia L.) and Banaba (Lagerstroemia speciosa L.) against Type 2 Diabetes Mellitus.

Summary

Philippines validated herbal medicines (MC) and (LS) have synergistic effects in managing Type 2 diabetes. Mechanisms of compounds in these herbs can inform treatment strategies and potentially reduce the cost of conventional medications.

Diabetes
Rivera RG Jr et al (2024).
Acta Med Philipp.
DOI:
10.47895/amp.vi0.7351
PubMed:
38812760

Comparative transcriptome and metabolite profiling reveal diverse pattern of CYP-TS gene expression during corosolic acid biosynthesis in Lagerstroemia speciosa (L.) Pers.

Genetics
Surendran K, Pradeep S and Pillai PP (2024).
Plant Cell Rep.
DOI:
10.1007/s00299-024-03203-0
PubMed:
38642121

Lagerstroemia speciosa Pers. (Lythraceae) Ethanolic Extract Attenuates Isoniazid-Induced Oxidative Stress and Hepatic Inflammation in Rats.

Immunology
Rohit Singh T et al (2024).
Cureus.
DOI:
10.7759/cureus.51609
PubMed:
38313882

Corosolic Acid Induced Apoptosis via Upregulation of Bax/Bcl-2 Ratio and Caspase-3 Activation in Cholangiocarcinoma Cells.

Jedram O et al (2023).
ACS Omega.
DOI:
10.1021/acsomega.3c07556
PubMed:
38222611

Integrating traditional ecological knowledge into habitat restoration: implications for meeting forest restoration challenges.

Haq SM et al (2023).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-023-00606-3
PubMed:
37559120

Exploring the Antimicrobial, Anticancer, and Apoptosis Inducing Ability of Biofabricated Silver Nanoparticles Using Lagerstroemia speciosa Flower Buds against the Human Osteosarcoma (MG-63) Cell Line via Flow Cytometry.

Summary

This study found that silver nanoparticles synthesized from flower buds have antimicrobial and anticancer properties, making them potential options for biomedical applications.

AntimicrobialCancer
Shashiraj KN et al (2023).
Bioengineering (Basel).
DOI:
10.3390/bioengineering10070821
PubMed:
37508848

The impact of tree species and planting location on outdoor thermal comfort of a semi-outdoor space.

Yang J et al (2023).
Int J Biometeorol.
DOI:
10.1007/s00484-023-02532-1
PubMed:
37500793

The Effect and Safety Assessment of Metformin and DLBS3233 (A Bioactive Fraction of Lagerstroemia speciosa and Cinnamomum burmannii) on Improving Metabolic Parameters in Women with Polycystic Ovary Syndrome.

Summary

This study tested the effectiveness and safety of DLBS3233, a new insulin-sensitizing drug derived from Indonesian herbals, alone and in conjunction with metformin, in women with PCOS and insulin resistance.

Endocrinology
Hidayat ST et al (2023).
Int J Womens Health.
DOI:
10.2147/IJWH.S409685
PubMed:
37424700

Identifying potent inhibitory phytocompounds from Lagerstroemia speciosa against SARS-Coronavirus-2: structure-based virtual screening.

Summary

Researchers found that 24-methylene cycloartanol acetate may inhibit envelope viroporin protein and RNA-directed RNA polymerase, while sitosterol acetate may target SARS-CoV-2 main protease, spike glycoprotein, and human receptor ACE2. Further testing is needed to confirm their safety and effectiveness as potential therapeutics. (63 words)

COVID-19
Singh Dagur H et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2205942
PubMed:
37170794

Antibacterial, Antioxidant, Larvicidal and Anticancer Activities of Silver Nanoparticles Synthesized Using Extracts from Fruits of Lagerstroemia speciose and Flowers of Couroupita guianensis.

Cancer
Babu V et al (2022).
Molecules.
DOI:
10.3390/molecules27227792
PubMed:
36431893

Lagerstroemia speciosa Ameliorated Blood Pressure in LNAME Induced Hypertension in Experimental Rats through NO/cGMP and Oxidative Stress Modulation.

Cardiology
Aleissa MS et al (2022).
Biomed Res Int.
DOI:
10.1155/2022/5894416
PubMed:
36262977

Antibiofilm and Quorum Sensing Inhibition (QSI) Potential of Lagerstroemia speciosa Leaves Extract.

Zafar F et al (2022).
Dose Response.
DOI:
10.1177/15593258221132080
PubMed:
36262717

Photosynthetic Parameters and Oxidative Stress during Acclimation of Crepe-Myrtle (Lagerstroemia speciosa (L.) Pers.) in a meta-Topolin-Based Micropropagation System and Genetic Fidelity of Regenerated Plants.

Ahmad N et al (2022).
Plants (Basel).
DOI:
10.3390/plants11091163
PubMed:
35567164

Bioactive compound from Lagerstroemia speciosa: activating apoptotic machinery in pancreatic cancer cells.

Cancer
Goyal S, Sharma M and Sharma R (2022).
3 Biotech.
DOI:
10.1007/s13205-022-03155-w
PubMed:
35371901

Acute and sub-acute oral toxicity Lagerstroemia speciosa in Sprague-Dawley rats.

Alkahtani S et al (2022).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2021.11.005
PubMed:
35280577

Flood signals in tree-ring δ(18)O and wood anatomical parameters of Lagerstroemia speciosa: Implications for developing flood management strategies in Bangladesh.

Rahman M et al (2022).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2021.151125
PubMed:
34688736

By restoring autophagic flux and improving mitochondrial function, corosolic acid protects against Dox-induced cardiotoxicity.

Cardiology
Che Y et al (2022).
Cell Biol Toxicol.
DOI:
10.1007/s10565-021-09619-8
PubMed:
34296331

Lagerstroemia speciosa (L.) Pers., ethanolic leaves extract attenuates dapsone-induced liver inflammation in rats.

Immunology
Rohit Singh T and Ezhilarasan D (2022).
Drug Chem Toxicol.
DOI:
10.1080/01480545.2021.1945079
PubMed:
34225555

Lagerstroemia speciosa (L.) Pers., ethanolic extract attenuates simultaneously administered isoniazid- and dapsone-induced hepatotoxicity in rats.

Rohit Singh T and Ezhilarasan D (2021).
J Food Biochem.
DOI:
10.1111/jfbc.13830
PubMed:
34155655

A Review of Natural Stimulant and Non-stimulant Thermogenic Agents.

Review
Stohs SJ and Badmaev V (2016).
Phytother Res.
DOI:
10.1002/ptr.5583
PubMed:
26856274

Adverse effects of herbal medicines: an overview of systematic reviews.

Review
Posadzki P, Watson LK and Ernst E (2013).
Clin Med (Lond).
PubMed:
23472485

Lagerstroemia speciosa extract inhibit TNF-induced activation of nuclear factor-kappaB in rat cardiomyocyte H9c2 cells.

Cardiology
Ichikawa H et al (2010).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2009.12.033
PubMed:
20045454