Larrea tridentata

Common Names: creosote bush, creosotebush

Ethnobotanical Studies

Studies

Rodents consuming the same toxic diet harbor a unique functional core microbiome.

Stapleton TE et al (2024).
Anim Microbiome.
DOI:
10.1186/s42523-024-00330-7
PubMed:
39080711

Natural Immunomodulatory Agents as a Complementary Therapy for Poxviruses.

Summary

Researchers identified polyphenolics and isoquinoline alkaloids as potential antiviral agents against monkeypox virus by targeting viral elements. Natural extracts from traditional plants also show promise. Urgent molecular studies are needed to confirm their anti-poxvirus properties.

Review Immunology
Ali SI and Salama A (2024).
Adv Exp Med Biol.
DOI:
10.1007/978-3-031-57165-7_22
PubMed:
38801589

Plants from Arid and Semi-Arid Zones of Mexico Used to Treat Respiratory Diseases: A Review.

Review
Dávila-Rangel IE et al (2024).
Plants (Basel).
DOI:
10.3390/plants13060792
PubMed:
38592789

Plant-soil microbe feedbacks depend on distance and ploidy in a mixed cytotype population of Larrea tridentata.

Gerstner BP et al (2024).
Am J Bot.
DOI:
10.1002/ajb2.16298
PubMed:
38433501

The desert woodrat (Neotoma lepida) induces a diversity of biotransformation genes in response to creosote bush resin.

Genetics
Greenhalgh R et al (2024).
Comp Biochem Physiol C Toxicol Pharmacol.
DOI:
10.1016/j.cbpc.2024.109870
PubMed:
38428625

Elevated atmospheric CO(2) drives decreases in stable soil organic carbon in arid ecosystems: Evidence from a physical fractionation and organic compound analysis.

Jensen KH, Grandy AS and Sparks JP (2024).
Glob Chang Biol.
DOI:
10.1111/gcb.17175
PubMed:
38337156

Toxin tolerance across landscapes: Ecological exposure not a prerequisite.

Dearing MD et al (2022).
Funct Ecol.
DOI:
10.1111/1365-2435.14093
PubMed:
37727272

In Vitro Antiviral Activity of Nordihydroguaiaretic Acid against SARS-CoV-2.

Summary

NDGA, a compound in Creosote bush leaves, demonstrated inhibitory effects on SARS-CoV-2, including RNA replication and spike glycoprotein expression, at safe cell concentrations. Potential as a COVID-19 therapy.

AntimicrobialCOVID-19
Villalobos-Sánchez E et al (2023).
Viruses.
DOI:
10.3390/v15051155
PubMed:
37243241

Hybridization in the absence of an ecotone favors hybrid success in woodrats (Neotoma spp.).

Klure DM et al (2023).
Evolution.
DOI:
10.1093/evolut/qpad012
PubMed:
36715204

Consumer pressure and supplemental pollination mediate shrub facilitation of a native annual desert plant.

Haas-Desmarais SM and Lortie CJ (2023).
Oecologia.
DOI:
10.1007/s00442-022-05309-2
PubMed:
36607452

Inhibition of Phytopathogenic and Beneficial Fungi Applying Silver Nanoparticles In Vitro.

Vera-Reyes I et al (2022).
Molecules.
DOI:
10.3390/molecules27238147
PubMed:
36500239

Eco-Friendly Reduction of Graphene Oxide by Aqueous Extracts for Photocatalysis Applications.

Verástegui-Domínguez LH et al (2022).
Nanomaterials (Basel).
DOI:
10.3390/nano12213882
PubMed:
36364657

Evolutionary importance of the relationship between cytogeography and climate: New insights on creosote bushes from North and South America.

Vidal-Russell R et al (2021).
Plant Divers.
DOI:
10.1016/j.pld.2021.11.006
PubMed:
36187552

nor 3'-Demethoxyisoguaiacin from Larrea tridentata Is a Potential Alternative against Multidrug-Resistant Bacteria Associated with Bovine Mastitis.

Genetics
Morales-Ubaldo AL et al (2022).
Molecules.
DOI:
10.3390/molecules27113620
PubMed:
35684556

Trio-binned genomes of the woodrats Neotoma bryanti and Neotoma lepida reveal novel gene islands and rapid copy number evolution of xenobiotic metabolizing genes.

Genetics
Greenhalgh R et al (2022).
Mol Ecol Resour.
DOI:
10.1111/1755-0998.13650
PubMed:
35599377

Successes and limitations of quantitative diet metabarcoding in a small, herbivorous mammal.

Stapleton TE et al (2022).
Mol Ecol Resour.
DOI:
10.1111/1755-0998.13643
PubMed:
35579046

Transcriptome characterization of Larrea tridentata and identification of genes associated with phenylpropanoid metabolic pathways.

Genetics
Ali MA et al (2022).
PLoS One.
DOI:
10.1371/journal.pone.0265231
PubMed:
35275977

Characterization of the antibacterial activity from ethanolic extracts of the botanical, Larrea tridentata.

Turner T et al (2021).
BMC Complement Med Ther.
DOI:
10.1186/s12906-021-03344-9
PubMed:
34172064

Cytoprotective effects of creosote bush (Larrea tridentata) and Southern live oak (Quercus virginiana) extracts against toxicity induced by venom of the black-tailed rattlesnake (Crotalus ornatus).

Genetics
Plenge-Tellechea LF et al (2022).
Drug Chem Toxicol.
DOI:
10.1080/01480545.2020.1856864
PubMed:
33297789

Chaparral.

Review
(2022).
PubMed:
31643676

Larrea tridentata Extract Mitigates Oxidative Stress-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells.

Morán-Santibañez K et al (2019).
Antioxidants (Basel).
DOI:
10.3390/antiox8100427
PubMed:
31557847

Polyploidy in creosote bush (Larrea tridentata) shapes the biogeography of specialist herbivores.

O'Connor TK, Laport RG and Whiteman NK (2019).
J Biogeogr.
DOI:
10.1111/jbi.13490
PubMed:
31534296

4,4'-[(2R*,3R*,4R*,5R*)-3,4-Dimethyl-tetra-hydro-furan-2,5-di-yl]diphenol.

Favela-Hernández JM et al (2012).
Acta Crystallogr Sect E Struct Rep Online.
DOI:
10.1107/S1600536812039359
PubMed:
23125788

Larrea tridentata (Creosote bush), an abundant plant of Mexican and US-American deserts and its metabolite nordihydroguaiaretic acid.

Review
Arteaga S, Andrade-Cetto A and Cárdenas R (2005).
J Ethnopharmacol.
PubMed:
15814253

Cytotoxic lignans from Larrea tridentata.

Phytochemistry
Lambert JD et al (2005).
Phytochemistry.
PubMed:
15797607