Laurus nobilis

Common Names: sweet bay

Ethnobotanical Studies

Studies

Laurus nobilis L. leaves Suppress Alcohol-Related Liver Disease by Exhibiting Antioxidant and Anti-Inflammatory Effects in Alcohol-Treated Hepatocytes and Mice.

Immunology
Lee M et al (2024).
J Med Food.
DOI:
10.1089/jmf.2024.k.0111
PubMed:
39212582

Essential Oils of Laurus nobilis L.: From Chemical Analysis to In Silico Investigation of Anti-Inflammatory Activity by Soluble Epoxide Hydrolase (sEH) Inhibition.

Immunology
Fantasma F et al (2024).
Foods.
DOI:
10.3390/foods13142282
PubMed:
39063366

Effects of Laurus Nobilis Eye Drop on Selenite-Induced Cataract Formation and Oxidative Stress-Related Parameters in Rabbits: An Experimental Study.

Immunology
Palazzo M et al (2024).
Curr Eye Res.
DOI:
10.1080/02713683.2024.2380440
PubMed:
39034665

Effects of Laurus nobilis Leaf Extract (LAURESH(®)) on Oral and Gut Microbiota Diversity in Mice.

Summary

L. nobilis leaves improve human health by altering microbiota. This study examines their effects on oral and gut microbiomes in mice. Important for potential health benefits in humans.

Gastroenterology
Morikawa T et al (2024).
In Vivo.
DOI:
10.21873/invivo.13626
PubMed:
38936916

Biological, phytochemical and molecular docking characteristics of Laurus nobilis L. fresh leaves essential oil from Palestine.

Phytochemistry
Jaradat N et al (2024).
BMC Complement Med Ther.
DOI:
10.1186/s12906-024-04528-9
PubMed:
38851735

The comparison of contribution of GO and rGO produced by green synthesis to the properties of CMC-based wound dressing material.

Karaca ÖG et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.132521
PubMed:
38772457

Combining the pharmaceutical and toxicological properties of select essential oils with their chemical components by GC-MS analysis.

Nilofar N et al (2024).
Chem Biodivers.
DOI:
10.1002/cbdv.202400738
PubMed:
38695450

Effect of Laurus nobilis on bacteria and human transforming growth factor-β1.

Sancer O et al (2024).
Rev Assoc Med Bras (1992).
DOI:
10.1590/1806-9282.20230683
PubMed:
38655992

Incorporating bay leaf extract (Laurus nobilis L.) and determining the quality attributes of Turkish fermented sausage (sucuk).

Benli H, Şahin P and Ağçam E (2024).
Food Sci Nutr.
DOI:
10.1002/fsn3.3929
PubMed:
38628223

Combined Effects of Zein Nanofiber Coating Containing Laurel (Laurus nobilis) and Air Fryer Cooking on Quality Properties of Fish Fillets during Cold Storage.

Ceylan Z et al (2024).
ACS Omega.
DOI:
10.1021/acsomega.3c06318
PubMed:
38434834

Characterization of the Complete Mitochondrial Genome of Wintersweet (Chimonanthus praecox) and Comparative Analysis within Magnoliids.

Genetics
Yu X, Feng Y and Zhang J (2024).
Life (Basel).
DOI:
10.3390/life14020182
PubMed:
38398691

Assessment of metals (Ni, Ba) deposition in plant types and their organs at Mersin City, Türkiye.

Koç İ et al (2024).
Environ Monit Assess.
DOI:
10.1007/s10661-024-12448-x
PubMed:
38369612

Anticandidal effectiveness of greenly synthesized zinc oxide nanoparticles against candidal pathogens.

Maniah K et al (2024).
J Environ Sci Health A Tox Hazard Subst Environ Eng.
DOI:
10.1080/10934529.2024.2315922
PubMed:
38351615

Could the aroma of spices produce a cross-modal enhancement of food saltiness and contribute to reducing salt intake?

Segura-Borrego MP et al (2024).
J Sci Food Agric.
DOI:
10.1002/jsfa.13270
PubMed:
38308484

The microclimate impact of treetop walk based on plant community simulation.

Lin Y et al (2024).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-024-32009-6
PubMed:
38280164

Efficient treatment of oily wastewater, antibacterial activity, and photodegradation of organic dyes using biosynthesized Ag@Fe(3)O(4) nanocomposite.

Hasan GG et al (2023).
Bioprocess Biosyst Eng.
DOI:
10.1007/s00449-023-02946-6
PubMed:
38081951

Aqueous extract of Laurus nobilis leaf accelerates the alcohol metabolism and prevents liver damage in single-ethanol binge rats.

Jung JI et al (2023).
Nutr Res Pract.
DOI:
10.4162/nrp.2023.17.6.1113
PubMed:
38053830

Zaluzanin C Alleviates Inflammation and Lipid Accumulation in Kupffer Cells and Hepatocytes by Regulating Mitochondrial ROS.

Summary

Zaluzanin C (ZC), a compound found in plants, has anti-inflammatory and antioxidant effects. It protects liver cells by reducing inflammation, improving mitochondrial function, and enhancing lipid metabolism. ZC could be an effective treatment for liver protection.

Immunology
Jung JW et al (2023).
Molecules.
DOI:
10.3390/molecules28227484
PubMed:
38005205

Bay Leaves Extracts as Active Additive for Food Protective Coatings.

Peña-Ortiz M et al (2023).
Foods.
DOI:
10.3390/foods12203741
PubMed:
37893634

The quality evaluation of the laurel leaf samples sold in the market under the name of "Defne Yaprağı".

Kendir G et al (2023).
Protoplasma.
DOI:
10.1007/s00709-023-01897-9
PubMed:
37816984

Neuroprotective and anti-amnesic effects of Laurus Nobilis essential oil against scopolamine-induced memory deficits in mice brain.

Summary

Laurus nobilis L. (a plant) has been used in Tunisian medicine for treating ailments like rheumatism and neurological disorders. This study explores its potential benefits, which could be useful for your lab's research in finding new treatments.

NeurosciencePhytochemistry
Smach MA et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117151
PubMed:
37689325

Microencapsulation of Laurus nobilis L. Leaf Extract in Alginate-Based System via Electrostatic Extrusion.

Dobroslavić E et al (2023).
Foods.
DOI:
10.3390/foods12173242
PubMed:
37685175

Efficiency of Recovery of the Bioactive Principles of Plants by Comparison between Solid-Liquid Extraction in Mixture and Single-Vegetable Matrices via Maceration and RSLDE.

Naviglio D et al (2023).
Plants (Basel).
DOI:
10.3390/plants12162900
PubMed:
37631112

GABase and glutaminase inhibitory activities of herbal extracts and acylated flavonol monoglycosides isolated from the leaves of Laurus nobilis L.

Shimada A et al (2023).
Z Naturforsch C J Biosci.
DOI:
10.1515/znc-2023-0047
PubMed:
37535009

Anti-Helicobacter pylori, Antioxidant, Antidiabetic, and Anti-Alzheimer's Activities of Laurel Leaf Extract Treated by Moist Heat and Molecular Docking of Its Flavonoid Constituent, Naringenin, against Acetylcholinesterase and Butyrylcholinesterase.

Summary

This study found that moist heat treatment of laurel leaf extract increases the concentration of certain beneficial compounds and enhances its antioxidant, anti-diabetic, and anti-Alzheimer's activities.

DiabetesImmunologyNeurosciencePhytochemistry
Al-Rajhi AMH et al (2023).
Life (Basel).
DOI:
10.3390/life13071512
PubMed:
37511887

Dietary supplementation of Nile tilapia (Oreochromis niloticus) diets with bay laurel (Laurus nobilis): alleviation of oxidative stress and amelioration of immune response, serum biochemistry, and resistance against Aeromonas hydrophila.

Immunology
Swamy JM et al (2023).
Fish Physiol Biochem.
DOI:
10.1007/s10695-023-01210-8
PubMed:
37450203

Control of Listeria monocytogenes in a fresh cheese using aromatic and medicinal plants and enterocin: a comparative study.

Ananou S et al (2023).
Lett Appl Microbiol.
DOI:
10.1093/lambio/ovad076
PubMed:
37401169

Determining the optimum mixture of three essential oils for potato sprout suppression at room temperature storage.

Thoma JL et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1199117
PubMed:
37389299

Erythema multiforme-like allergic contact dermatitis from bay leaves in a home-made natural remedy.

Dermatology
Martínez-Fernández A et al (2023).
Contact Dermatitis.
DOI:
10.1111/cod.14327
PubMed:
37105538

Interaction of Laurusides 1 and 2 with the 3C-like Protease (M(pro)) from Wild-Type and Omicron Variant of SARS-CoV-2: A Molecular Dynamics Study.

Summary

Laurusides, compounds found in bay laurel, have potential as COVID-19 treatments. Molecular simulations found they interact well with both SARS-CoV-2 and the Omicron variant, suggesting their usefulness as antiviral therapies.

COVID-19
Autiero I and Roviello GN (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24065511
PubMed:
36982585

Plant-Based Antioxidants for Prevention and Treatment of Neurodegenerative Diseases: Phytotherapeutic Potential of Laurus nobilis, Aronia melanocarpa, and Celastrol.

Review Neuroscience
Pilipović K et al (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12030746
PubMed:
36978994

A novel biosynthesis of MgO/PEG nanocomposite for organic pollutant removal from aqueous solutions under sunlight irradiation.

Mohammed Mohammed HA et al (2023).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-023-26422-6
PubMed:
36928702

Safety and efficacy of a feed additive consisting of an essential oil from the leaves of Laurus nobilis L. (laurel leaf oil) for all animal species (FEFANA asbl).

Phytochemistry
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) et al (2023).
EFSA J.
DOI:
10.2903/j.efsa.2023.7875
PubMed:
36908566

Predicting of the current and future geographical distribution of Laurus nobilis L. under the effects of climate change.

Akyol A et al (2023).
Environ Monit Assess.
DOI:
10.1007/s10661-023-11086-z
PubMed:
36897509

Evaluation of daily Laurus nobilis tea consumption on anxiety and stress biomarkers in healthy volunteers.

Chbili C et al (2022).
Arch Ital Biol.
DOI:
10.12871/000398292022343
PubMed:
36881915

Investigation of Molecular Mechanisms Involved in Sensitivity to the Anti-Cancer Activity of Costunolide in Breast Cancer Cells.

Cancer
Choi YJ et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24044009
PubMed:
36835418

Corrigendum to "Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement of mitochondrial biogenesis - Possible implication in pharmacotherapy" [Mitochondrion 59 (2021) 190-213].

DiabetesGenetics
Bourebaba N et al (2023).
Mitochondrion.
DOI:
10.1016/j.mito.2023.01.008
PubMed:
36725392

Evaluation of the Effect of Alcoholic Extract of Laurus Nobilis Leaves on Blood Biochemical Parameters and Histological Changes in the Liver and Kidney among Female Wistar Rats Treated with Depakene (Sodium Valproate).

Shnewer Mahdi Al-Turfi Z et al (2022).
Arch Razi Inst.
DOI:
10.22092/ARI.2022.357272.2011
PubMed:
36618289

Chitosan and Essential Oils Combined for Beef Meat Protection against the Oviposition of Calliphora vomitoria, Water Loss, Lipid Peroxidation, and Colour Changes.

Phytochemistry
Farina P et al (2022).
Foods.
DOI:
10.3390/foods11243994
PubMed:
36553736

Verification of exposure to chemical warfare agents through analysis of persistent biomarkers in plants.

de Bruin-Hoegée M et al (2023).
Anal Methods.
DOI:
10.1039/d2ay01650h
PubMed:
36524843

Chemical Composition, Antioxidant, Anti-Diabetic, Anti-Acetylcholinesterase, Anti-Inflammatory, and Antimicrobial Properties of Arbutus unedo L. and Laurus nobilis L. Essential Oils.

Summary

The study assessed the chemical composition, antioxidant, anti-diabetic, antibacterial, anti-inflammatory, and anti-acetylcholinesterase activity of two plant essential oils. Both oils were found to have significant biological effects, including inhibiting carbohydrate-hydrolyzing enzymes and antimicrobial activity. One oil was found to be a better inhibitor of acetylcholinesterase and the other showed a greater anti-inflammatory effect. In vivo studies confirmed the anti-inflammatory effect. The study highlights the potential of these oils as natural drugs with significant therapeutic properties.

AntimicrobialImmunologyNeurosciencePhytochemistry
Al-Mijalli SH et al (2022).
Life (Basel).
DOI:
10.3390/life12111876
PubMed:
36431011

Phytochemical profile and anthelmintic effects of Laurus nobilis essential oil against the ovine nematode Haemonchus contortus and the murine helminth model Heligmosomoides polygyrus.

Phytochemistry
Sebai E et al (2022).
Vet Parasitol.
DOI:
10.1016/j.vetpar.2022.109835
PubMed:
36306627

Cinnamtannin B-1 Inhibits the Progression of Osteosarcoma by Regulating the miR-1281/PPIF Axis.

Jia J et al (2023).
Biol Pharm Bull.
DOI:
10.1248/bpb.b22-00600
PubMed:
36273900

Effect of multifactorial free and liposome-coated of bay laurel (Laurus nobilis) and rosemary (Salvia rosmarinus) extracts on the behavior of Listeria monocytogenes and Vibrio parahaemolyticus in silver carp (Hypophthalmichthys molitrix) stored at 4 °C.

Genetics
Aala J et al (2023).
Environ Res.
DOI:
10.1016/j.envres.2022.114478
PubMed:
36206926

Adsorptive removal of hazardous dye (crystal violet) using bay leaves (Laurus nobilis L.): surface characterization, batch adsorption studies, and statistical analysis.

Isik B et al (2023).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-022-22278-4
PubMed:
35915311

Laurel essential oil: biological activities and application for semolina preservation against the red flour beetle Tribolium castaneum (Tenebrionidae).

Phytochemistry
Haouel-Hamdi S et al (2023).
Int J Environ Health Res.
DOI:
10.1080/09603123.2022.2093338
PubMed:
35765827

A Review of the Botany, Volatile Composition, Biochemical and Molecular Aspects, and Traditional Uses of Laurus nobilis.

Review
Paparella A et al (2022).
Plants (Basel).
DOI:
10.3390/plants11091209
PubMed:
35567209

Biological control of Citrus brown spot pathogen, "Alternaria alternata" by different essential oils.

Grati Affes T et al (2023).
Int J Environ Health Res.
DOI:
10.1080/09603123.2022.2055748
PubMed:
35322739

Bay Laurel (Laurus nobilis L.) Essential Oil as a Food Preservative Source: Chemistry, Quality Control, Activity Assessment, and Applications to Olive Industry Products.

Review Phytochemistry
Ordoudi SA et al (2022).
Foods.
DOI:
10.3390/foods11050752
PubMed:
35267385

Artecanin of Laurus nobilis is a novel inhibitor of SARS-CoV-2 main protease with highly desirable druglikeness.

Summary

Researchers conducted a study to find natural compounds from medicinal plants that could inhibit the main protease (M) enzyme of SARS-CoV-2, which is critical for the virus's life cycle. They identified artecanin as the most potent compound with excellent safety and drug properties through virtual screening and molecular dynamics simulations. Artecanin has the potential to be used as a natural inhibitor to prevent or mitigate COVID-19.

COVID-19
Al-Shuhaib MBS et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2022.2030801
PubMed:
35067202

Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement of mitochondrial biogenesis - Possible implication in pharmacotherapy.

DiabetesGenetics
Bourebaba N et al (2021).
Mitochondrion.
DOI:
10.1016/j.mito.2021.06.003
PubMed:
34091077

Laurus nobilis, Salvia sclarea and Salvia officinalis Essential Oils and Hydrolates: Evaluation of Liquid and Vapor Phase Chemical Composition and Biological Activities.

Phytochemistry
Ovidi E et al (2021).
Plants (Basel).
DOI:
10.3390/plants10040707
PubMed:
33917630

Biomedical effects of Laurus nobilis L. leaf extract on vital organs in streptozotocin-induced diabetic rats: Experimental research.

Diabetes
Mohammed RR et al (2020).
Ann Med Surg (Lond).
DOI:
10.1016/j.amsu.2020.11.051
PubMed:
33520200

Laurus nobilis leaf extract controls inflammation by suppressing NLRP3 inflammasome activation.

Immunology
Lee EH et al (2019).
J Cell Physiol.
DOI:
10.1002/jcp.27434
PubMed:
30387132